May 2026 Q&A | Retatrutide, Testosterone, Autoimmune, and Beyond

0:00 Hey everybody, this is Hunter Williams. I hope you're doing amazing wherever you might be in the world. Today is the May, 2026 Q and A video. So I have tons and tons of questions. Actually printed them off because I like reading these when I print them all here and I've got them grouped by category. so I am going to do my best to get through all these and have my pen because some of them are similar so don't need to go over them. twice, but I have grouped them by category. So we are going to dig into the questions. As always, before I get started on this, if you want to submit questions, that will be on my links page.

0:34 You can always click on the links pages that's in the description, and then you can scroll down and it'll have a little place that you to submit a question to me that goes to a email inbox that I have set up that i go through and look through all these it also gets put onto a document that. I then take and am able to now use all of the large language models to organize them by theme and then I can go. Through and answer the question so. We're going to jump into that today. Obviously, if you want to work directly with me and have me actually answer your question in a private message or in the forum,

1:06 join the Axion Collective. As always, make sure you're on the email list because with censorship, that is the best place to stay in touch with. Me, obviously I have all of my socials up right now, but you never know when they are going because I think in this industry, it's only a matter of time, not a manner of if they're going to get taken down. But I'm gonna stay positive and we're gonna make sure that we keep all of the ones that I currently have up. Without further ado, let's get into it. Also, Before I forget, I did make an AI tool. So I basically have this AI bot, but I guess that it is only trained on my material.

1:41 What I was able to do is I took all of the videos I've ever made and I uploaded it into this tool that I built myself. And basically it will answer your question as if it were the video's meaning that only draws on that data set. It's not like ChatGBT or Grok or Claude. in the sense that it only answers if I've answered that question or talked about your question in a video. And so if you asked it, you know, like what color are unicorns on Mars? It's not going to know. It is not gonna come up with an answer like most of the AIs will.

2:11 So if want to check that out, it's pretty cool. and go play around with that. So I've heard from a lot of people and they say they really like it so far and I have seen some of the answers. Obviously I tested it a bunch myself and the answer seemed to be pretty good. It's not going off the reservation and saying things that I don't talk about. Um, it literally will just match whatever your question is to anytime I talked about that in the video, whether it's a podcast, solo video Q and a video live stream, whatever, they will answer that so without further ado, let's start it.

2:42 First one, pretty relevant to my life right now. Kathleen says, GOP's infertility and mid twenties woman wanting to lose weight before pregnancy. I do think this is something you've probably heard the term ozempic baby. And so I think GOPs are definitely enhancing fertility on the female side. The male side, I think is yet to be determined how well that's doing. We know transiently, some of the GOPs seem to raise testosterone levels in guys that are obese. I don't think it's do anything into guys who are actually healthy from a weight standpoint. You're not getting a bump in testosterone from the GLP, but in women does seem enhancing fertility outcomes in Protocol wise,

3:19 I would just say use whatever you need to to lose the weight, to get to your goal weight. But then also too, stop the GLP once you get pregnant. I don't think it's probably the best thing to be on the glp while pregnant, although I know people are doing that and it doesn't seem like it is causing any problems, but I personally, hopefully, fingers crossed when my wife does get pregnancy, she will be discontinuing a GLp, albeit she's on a low dose. Next question is from Macaulay. He says, uh, GLP one constipates me what to do instead.

3:49 I mean, you could obviously go off of the GLPs. My recommendation would be a probiotic, a prebiotic, fiber supplement in addition to the pre biotic. And then also make sure you're on a really good dose of magnesium because that will help as well. Honestly, magnesium citrate, I always tell people there, everyone has a threshold dose. Of magnesium, such rate that we'll work for you. It might be 300 milligrams, might 600 milligrams. Might be 1200 milligrams be 2,500 milligrams, it might be 5,000 milligrams. At some level, you will evade constipation with magnesium citrate.

4:21 Again, that's going to be uncomfortable, but I would rather be comfortable and not constepated than constapated and uncomfortable. So that would be my recommendation. But honestly, those things right there usually help speed things along. Also too, for people that do have sort of like gastric imping issues, apple cider vinegar, aloe juice, glutamine and lemon juice. If you just make a little concoction of those together, they work really well. And I do that myself sometimes. All right. Hunger increased on reddit with no loss.

4:52 I talk about this a lot. When it comes to hunger increasing on Reddit, it's probably because you're in an energy deficit. The easiest answer for me is if you want to, you can go up on the dose. Now that doesn't mean it is going to fix the hunger in all cases, but in a lotta cases it seems like the two to four milligram dose in lot of people makes them hungrier. Once they get over the four-milligram dose, that does not have the same effect. But some people does. And I always say you can always add in a little bit of trisapatite with your red atriotide. You can also add a bit coagulantide, you always can add some tesofensine. We forget about teso-fensinine and how good that is.

5:23 So that would be my recommendation there. This is a good question from Dan. He says, when we look at dopamine and reward pathway effects across red aterus and sema, are there differences? In my opinion, what it seems like is that the GLP-1 pathway seems to be modulating the dopamine the most. And so higher doses of semaglutide, because obviously that's just GLp-one, seem like they are going to cause more of the issues with dopamine. Thus higher doses of turzapetide seem like it would cause less than semaglutide milligram for milligram and retrutide, same thing,

5:57 milligram from milligram, probably less. However, a lot of people can get dopamine issues with all three of them. So really comes down to a person. I think the GLP-1 receptor in my experience is what is causing most of the dopamine down regulation in people that end up having issues. Some people, that's actually a really good thing because it keeps them from being addicted to whatever they're addicted But when we talk about dopamine, it seems like Reta seems to be the least affecting of dopamine. Although still affecting it, TERS a little bit more, and obviously semen glutide the most. But I've talked to people that have taken all three that had issues.

6:27 So you kind of have to use it. And then when Dopamine and what we can do, like if you want to stay on the GLP, we could obviously use something like a tesofensine to help. There's actually L-tyrosine that could help, 5-HTP could be beneficial, 9-MeBC could beneficial. So there are things that are dopamine increasing type supplements that you can use. Next question from El or Eli, excuse me, is RETTA the best GLPs for fit and carnivore protein heavy trainees doing body recomp?

7:01 I think it is, although I would be leery of doing the carnivore diet on Reddit or a keto diet, on reddit. And here's why you want to do that. That works for you by all means, please do. I really stay away from getting preachy on diet because I'd think different diets work for different people. You should do what you. However, when we take a compound that slows down digestion, it has beneficial to have fiber alongside that compound. Also, when we look at carnivore diets, keto diets.

7:31 What are they typically heavier in? Fats. When you have a lot of fats that also slows digestion. And so I have seen in my own experience and people that I've worked with, People that have carbohydrates, particularly clean carbohydrates fruits, vegetables, rice, potatoes, that actually helps their digestion feel better. Their body is more insulin sensitive because of the peptide and they don't have the issues. Whereas if you're eating 300 grams of fat per day with no fiber, that is going to dramatically slow digestion on top of digestion that has already slowed

8:07 from the peptide. And so in my opinion, that does not the best thing. However, you got to do what's best for you. In some people, the diet is the better for them. It would just be something that I would reconsider if you are doing that diet and you're introducing a GLP peptides because we are not dealing with the same tool set or same sample set as we would be if a person was not on those peptids. And so that's my opinion around that, but got to do what works best for you. Karen says five weeks of RETA titrated to 1.75 milligrams, appetite suppression is gone.

8:42 Young low body fat female up the dose, add category or switch to TURS. Well, I always like to remind people a lot of times the hunger is there for a reason. And especially if someone is low-body fat, they are inducing a caloric deficit. You're having a blowback when we look at ghrelin and leptin to which the body is going to start sending signals through those ghrelin and Leptin hormones. that you need to eat. And in a lot of cases, that's what's happening is we're burning more calories. We're usually eating less. So the body is trying to signal you, hey, I need some food here. That's oftentimes what is happening.

9:12 Obviously, you can either eat more food. A lot times you could eat food and you still lose weight. It kind of sounds common to it, but you eat a little bit more, and then you're actually burning calories, so I think that is a good strategy. You can obviously add coagulantide, which works on a different pathway via amylin to suppress appetite. Or you could add trisapatite, switch to trizapatide, whatever you want to do. So kind of depends, but those would be my recommendations. Karen says, lost access to semaglutide. Started retitrutide at two milligrams, no results, and I need to lose 100 pounds.

9:44 Unfortunately, for someone that needs to loose a hundred plus pounds, you really are going to have to increase the dose. And I think this is where we talk about the higher doses of retritrutite of trzapatitide the eight, 10, 12 milligram dosing. This would be the appropriate use case for those. So I make no illusions that someone could take two milligrams of Rettutide, they need to lose a hundred pounds. They're probably not going to loose the weight as fast as they want to. I think they'll still lose weight, but they will probably have to titrate over time. Over an eight to 12 week window up into those higher doses to get the results that they Beth said, can you add Mazdootide to 1.25 milligrams of Ritrutide

10:19 for more glucagon? Yeah, you definitely could. I have not done that. And I've not combined those two specifically, but you probably could, I would just be aware, probably going to get an increase in heart rate alongside that, so just to be advised that that's possible. But I will not have such an issue doing that let's see, talked about that already. Dwayne says 61 year old started Reta was on digestive enzymes with delayed gastric emptying. Do enzymes hinder RETA? No, I would say they are actually very beneficial.

10:49 So in my experience, use digestive, enzymes, every single meal. Now, whether or not that's a good thing. I don't know, but I've been doing that for years, even before GLPs, just because they help my stomach and help digestion. Especially if you are eating more protein seems like I absorb the protein better, maybe that is anecdotal on my part. But I would say that digestive enzymes are very beneficial alongside of a GLP. It's actually something I don't really talk about probably enough of how beneficial digestive, enzymes can be with your GLPs. Also another compound called betaine, similar to digestive.

11:20 Enzymes works really well. And I take that all the time. So great question. Next one. Uh, sorry, I'm just going through some of these that we already talked about. Kiva says I did an eight week, read a cycle now off what to do to keep momentum until next cycle. So kind of the same thing, you can keep doing it. You can come off of it, You. Can throw in a different one, like a tesofensine, Like a coagulantide like an or for Gleapron and go from there.

11:52 And so you don't always have to come after eight weeks. I would need to know more situationally there, but those are kind. Of what I. Would think. Question here, someone switched from TERS to RETA and they had really bad anger, anxiety, and irritability, even just at 400 micrograms. Went back to Ters-Aptide and was fine, loved the Reta otherwise. Why? It's interesting, it could be just obviously if you're doing final Tters-aptide in the Reta, the difference is the glucagon. So potentially something there, whether it was the calorie deficit, whatever it is, energy deficit.

12:24 Uh, your body didn't like that. So I would, when I hear anger, anxiety, and irritability, I'd like to think, okay, hormonally, what's going on there? And potentially maybe there was a negative cascade hormonaly created. That would be my only guess, guesstimate there. Um, but again, if you do good on trisapatite, don't think there's any shame on using trizapatide over red trutide. I always tell people, you can get all the fat loss you need on Trisapatite alone. Greg 58 years old, lost 90 pounds over three years. Good job. And then plateaued type two diabetic on Manjaro.

12:55 What is the best for fat loss and muscle regain? First thing I'm always going to tell people is hormone optimization, particularly if you lose that much weight. There is a neuroendocrine cascade that is created through your hormones that usually down regulates from losing that weight because the body was in our starvation period. that would be my recommendation for fat loss and muscle gain long term is to have hormones in check. And then obviously you can go to a growth hormone peptide and then potentially something like Amatsi to help as well.

13:26 Um, Henrik says, why do GLP stop working when you cycle off and back on cycles per year off SS 31? What is my longevity stack? Well, we'll get into the longevity snack, but I will say when people cycle of GLPs, obviously a lot of these people are regaining the weight. I think it's a of things. One, you're just not going to burn as much calories and eat less when they're off of a GLp. Kind of makes sense, right? But I will say a lot of these people are not foundationally addressing their hormones, their thyroid, and all the other things that would help them stay

13:56 lean once they get to their goal weight. And so again, do we want to rely on a GLP? I plan on taking GLPs for the rest of my life. However, I would say, a lotta times these are people not doing the foundational things. And this is good because I get so many questions about this and it's definitely a thing of like, when I cycle off a GLP, nothing else is working. In a lot of cases, these people are not on testosterone, they're not thyroid, or a growth hormone peptide or on MOTC or SS31. And so when all those things are in place, typically they tend to do better coming off the GLPs.

14:29 Then you can go down to cycling a micro dose of a glp throughout the year and get the benefits without having to high doses. Stacy said, 10 weeks on Reddit, last few shots got red and itchy with risk and sensitivity. Do you have an allergy to stop? Well, with the itchiness, it potentially could be an analogy to it. I would say the skin sensitivity is something I've experienced and I know a lot of people experience in higher doses. And usually it's around that 10 week mark that tends to kick in. Why it happens, I don't know. We don't really know yet.

14:59 There's nothing I could find in the research to indicate as to what is going on there. However, I have seen topical magnesium do really well for people. So that would be something I would look at if you are bothered by the skin sensitivity, because that worked for me and I've heard it work well, for other people too. Ray Shell says, doctors mixing GLP-1 with B12 or BPC in the same syringe opinion. I think the B-12 is probably fine. Bpc, I haven't seen anything to confirm or deny whether it is stable with that. Although I do think that a lot of compounding pharmacies are doing this to get around the quote unquote patent on the GLPs.

15:33 The interesting thing about patents on GLPS is that they were all discovered and originated from the NIH. NIH is taxpayer funded. Now, Eli Lilly brings those drugs to market and then commercializes them, but they were all discovered and originated from a taxpayer funded organization. So it's kind of funny the amount of money that's made on GLPs when it was actually American tax dollars that discovered the drug. Stick that in your pipe and smoke it and a little bit of food for thought there, But kind-of funny how this all works, isn't it?

16:06 Marcy says, GLPs cause anhedonia for me, tried semiturs, read a low dose. What to use for fat loss? Well, if you were going to remove GLP's from your stack because of the anhendonia, there are things that I mentioned earlier around dopamine that you could think you can try. But we talk about anhadonia. Testofensine, I think could be a great thing. Some people get anhedonia on chagrelin tides, some people don't, so maybe we could try that. And I would say from there, there's obviously MOTC, growth hormone peptides.

16:36 There's BAM15, SLU, PP332, albuterol. If you go to a video I have, it's called the non-GLP fat loss tier list. They're not GLPs to help with fat losses as well. actually says, do you need to be fasted when taking FOX04DRI? Seems to me beneficial. I don't know if there's a definitive answer on that. But do we need go off of all the other peptides while taking Fox04 DRI.

17:07 My personal experience is that you don't need to be off of all of your other peptides. I guess in theory, because it's a senolytic, you want to work on your cells with other peptides when you're clearing out senescent cells, but I don' know why that would matter because if you are working on other cells that are not senesen, and the FOXO4 is clearing our senencent cell, I do not know you need be all over or off all other Peptides, so I'm not sure where that came from, But in my experience I've used FOxO 4 in short cycles along with some of my other peptide and I felt the effects and it seemed to worked fine.

17:38 Oral vitamins recommended while on Reta from Pamela, I will say definitely a daily multivitamin. I use Thorne right now. Definitely taurine, definitely some magnesium, Definitely lots and lots of electrolytes, and definitely fish oil, vitamin D3, K2, which I would do anyway. So basically the answer is everything that you would without RETA you'd want to do, but you may need to supplement a little bit more, especially when it comes to the electrolyte. Sabina says on 30 milligrams of desiccated thyroid after one reticycle T4 lower, second cycle isn't working.

18:10 Did red affect thyroid? It definitely can. And so, uh, I don't know what the T four number was here, but it definitely and so that's where you may need to bump up to 60 milligrams, which is more of the standard dose of armor or desicated thyroid. So that would be my recommendation. Microdosing red at one milligrams per week for longevity stack, low dose, Tesso, fencing at 160 micrograms for energy. Don't get lift from red. Yeah, I think that's a great thing. You can definitely get a lot of energy from Tessa fency. And you may need to go up to higher to 250 micro grams though.

18:45 Question here about TURS versus RETA in women. Studies show women lose more on TIRS interaction with estrogen. Potentially, I don't know. I think that's one of those things, like maybe that just playing out. Don't think we have enough data yet, but maybe. Have talked about that in the past of like the sex differences on GLPs. Seems like sometimes women need more, sometimes men need though. So I really think it just depends on the person. Um, question on GOPs and sex and libido, does it affect it? Yeah. And a lot of people, because, uh, in my opinion, the dopamine, it can definitely do it.

19:16 Although I've seen it the opposite to where a lotta people have an increased libidio and a lots of times it's cause they're getting rid of inflammation in the body. So it kinda goes both ways. All right, let's move on to some hormones and HRT. Um. Rebecca says 53 year old told not a TRT candidate. Well, I don't think that's probably accurate from your doctor, but anyway, SHBG is 55 free T is low. How to lower SHPG and raise free tea.

19:48 The easy answer would be, you can take Boron and zinc typically would do it. But I, uh, don' know why someone would not be a Trt candidate a lot of times you'll hear this for people. If they have had a history of cancer, they're not candidate, But in a lotta cases that might be the best thing for them. So, um, that would my answer there. A lot of these are just asking where to find a doctor, which I'll have more info on coming soon because I'm working on a company on that. Joseph says, for male fertility, I have low T benign pituitary adenoma off TRT for nine months told to try to kiss pepta and PT-141.

20:22 You could try that, but I would actually add an HCG and HMG though for those specific things. Laurie asked about kiss-peptin for men and women, hormone regulation of female fertility. I would say, and I've been experimenting with this, Taylor and have a little bit ourselves. Kiss-Peptin 30 minutes before sexual intercourse does seem to help with fertility, so we've trying that. Fingers crossed, we'll see what happens. But it does help. It is not a long-term solution for hormone replacement. So fertility, potentially enhancing, yes.

20:54 But in terms of getting our hormones where we need them to be, I don't see that as a long-term solution. And also a lot of people, too, get a libido boost from kisspeptin as well. So you could try it for that. Dane says 30 year old male narcolepsy and IBS training for high rocks can excessive work cause low free T and in obviously in this case it's drug tested so they don't want to use TRT. So how would I raise free tea? Honestly, I would do as much as I could to lower the nervous system stress which is happening a lot of times in over training and also to injectable carnitine

21:31 if you couldn't use testosterone for any reason or any other performance enhancing drug. L-Carnitine is not banned by any bodies that I know of. So you could do that. And that would probably be the best answer. I guess you can try Testogen too, because it's technically not a banned, but I don't know that it does that much. Ashley says 56 year old female on HRT training five times a week. Her levels or hormone levels dropped drastically patch versus cream. Um, should she increase her progesterone from 200 milligrams?

22:03 I think injections are always going to be the best way, whether it's testosterone or estradiol. I always think injection tool better and you can potentially experiment. Every woman is going be different. Some women need 100 milligrams of progeterones. Someone men need 800 milligrams or progessorone. So I would just, I was just experiment with it, but if you're not sleeping well, Next one, 64 year old female want to inject tea, but your approach won't suit me. Gel only grows facial hair, need libido and energy. I don't know why the approach wouldn't suite you.

22:34 Reach out to me and I could probably help you find a doctor that will give you injectable testosterone as a woman because it seems to really help in most cases. John says, 63 year old slim fitness enthusiast, should I take DIMM, which is basically a herbal aromatase inhibitor. So it's not as strong as the chemical aromatase, inhibitors like an Astrazole or like Aromacin or Tamoxifen or whatever. But should take dim? I personally would not. I don't know that taking dim is going to do anything.

23:05 It's really going boost your testosterone. Sure. it does reduce the expression of aroma taste, but I think that metformin is a better aromatase inhibitor for people that are trying to get the intended effect. And not only does it not harm you like the aromates inhibitors does, but it makes you healthier. So that would be my recommendation for that specific. Talked about that one.

23:35 So we've got a perimenopausal woman, low estrogen, progesterone, blood work, but no symptoms. Already on T, get ahead of menopause. Yeah, I would say if you're already on testosterone, definitely start progesterone. You might not need the estrogen but you very potentially well, especially if your already taking testosterone and it's low. And so I will say potentially you want to add in estrogen. But definitely progeserones before you would do the estrogens, see how you feel and then potentially add an estradiol on top of that.

24:06 40s to 50s perimenopausal woman undecided on HRT and peptides, where to start, how much blood or how to much start with blood tests first. Obviously get your blood work done first, that's going to kind of lead you into the right direction that you need to. But my opinion is to to testosterone before we start a bunch of different peptide. I think GLPs are probably fine to, you know, but it's, again, it not going fix the foundation. So I like doing that, Oh, wow. So Shane is a 47-year-old male starting TRT.

24:38 Game day, I guess game day men's health told him starting at 60 milligrams a week. Friend said to start at 250. What should I do? My current testosterone is 225. I definitely would not do 60mg a weak and here's why. This is something I feel like I've talked about before. Probably not enough though. When it comes to testosterone, 60 mg a week. Here's what, in my opinion, that's going to do to you. your total testosterone is 225 right now. So not bad, but, or excuse me, it is bad but it can be fixed. It is that, I mince my words there.

25:09 Is bad. You want to be fix. Here's what will happen if you start 60 milligrams a week, you're going to shut down your natural production but your totally testosterone will stay at 226 probably because you are not going be getting enough to actually reach therapeutic levels. I don't know why doctors do this. And I know game day is a franchise, so like they probably have different doctors practicing different ways at each one. I don't know why they do this though, because it's kind of, what you're doing is you are shutting down your natural production by taking exogenous testosterone, but then you aren't taking enough to get the levels to where you going to feel good.

25:40 So I think net you just look, you not changing anything. You are just shutting your production with a small dose of testosterone that is not going make you feel better and then just feel the same and you have shut down you natural productions. My opinion, like your friend told you, is to go up to 200-200mg per week and go from there. It's really sad I highlighted this one because I wanted to talk about this because this is what's going on. I think even 100 milligrams to 120 milligrams a week is a lot of times too low because you shut down your natural production and it doesn't get your levels

26:12 into therapeutic ranges. So I like to start guys at 200 milligrams per week. If that's too high, you can always back down the dose. But in a lot of cases, that's actually exactly where they need to be. And I know really good doctors that I learned that from and that sort of practice because they started 200, but it's too high. You can always take it down. But if you start at 60 and it is too low, then you don't feel better. Then you're like, well, I go up. I'll go to a hundred. Do I feel anything? No. 120. do I fell anything. Maybe. Okay. and then, you go in this like six month long process where you basically just wasted your time. So start it 200. Go up and down from there is how I like to think about it.

26:46 All right, let's move on to some GH peptides and talking about IGF. All Right, common question that I get all the time. So Katia says systemic reaction to Tessa and most GH Peptides except IGFLR3, permanent, potentially. What I would do is move to growth hormone because most people with growth being bioidentical can use, especially in the case of a woman, half an IU, one IU per day and do really well on that. And it's going to work better than all of the GH peptide.

27:16 That's kind of, I mean, it's not the answer a lot of people want to hear, but that's like, okay, if you have this immune reaction to these, we'll just take the real thing and most people don't have any bad reaction. You will have to figure out your dose. All right. Frank says taking three, I use a GH five days a week TRT 15 milligrams daily. Should I bump the GH to three and a half to four? I used for fat loss kick or restart AOD. I don't know that going up from three to. Four I us is really going to do that much more for FatLoss. And so I would probably add in some of the GLPs maybe sure if you want to the AOT, maybe a MOTC, uh, may be an SLU, Maybe a BAM 15. Uh,

27:54 and then kind of go from there. So, Anya says young female using IGF to rebuild muscle 20 to 50 micrograms pre post workout to three times a week, six to 12 months, reasonable daily only. No, that's reasonable, except for the fact that it's six or 12 month. What I would actually do is just do that in like four to six week cycles. And you could probably go up on the dose closer to like 100 micro grams per dose. doing it pre and post workout. And so like you would build up to like maybe the total daily dose would be 200 micrograms on those two to three days per week.

28:29 But the reason is I think after four to six weeks, you really don't get that much of an effect. I like to cycle that one off just because IGF levels will go systemically and we don t want to artificially inflate those for a very long period of time because we just don' t really know what's going to happen from there. Lauren says liquid MK777 versus pill form. Is there a difference in absorption? My experience, there's not. I just take the pills because a lot of times the liquid tastes nasty. So I think you can get whatever one you want and then just go from there. Again, MK 777, I make no illusions that we have clinical data on that.

29:03 This is literally just anecdotal experience. So just know when you're taking that, it worked really well. I liked it better than MK 677. But we haven't no papers, no rodent papers. No human papers so we don't really know what it is. We don' really have any verification. It's just kind of one of these things that made its way into the research world and now we it out there and it's circulating. Cat says running IP on CJC, no DAC five on two off dinner at six 30 asleep at nine. Okay. To set alarm to inject four hours after dinner. Sure.

29:33 If you want to, I think you, if you eat dinner nine, it's fine to take right before bed. That should be enough time to help with that. There is, that makes me think there is this question about, If you're on a GLP and you are taking a growth hormone peptide with the GLPs slowing gastric emptying, do now you have to wait extra long to take your growth on peptides because your digestion is slowed. I don't think it's that big of a deal to be honest. Like if you were waiting two hours, you probably fine. You just want to make sure that your insulin and blood sugar are coming back to normal. So check your bloodsugar.

30:04 If it is back normal, your probably find you want circulating levels of insulin to lower because obviously that's more helpful. But I think its one of those things. Obviously, You want it to be as close to a fastest state as possible. What I really wouldn't, I wouldn' worry about it that much to the point of it not working. All right. Let's talk some injury healing and recovery. Frank says confused about injury stacks. There's too many options. Your go-to protocol. Pretty much all injury questions can be answered like this. Take the clove blend with cartilax at one to two milligrams and PEG-MGF at 200 or 400 micrograms.

30:41 Those six peptides right there will do wonders for injury. So much even more beyond BPC and TB 500 alone. You have the KPV, the GHK, cartillax and the PEgMgf. Michael says for skin removal surgery after 100 pound Reta assisted weight loss, what would be a healing stack pre and post? Um, I would do those ones just there that I talked about. So CLO plus carlax plus P E G F would my answer.

31:11 Um. Talked about that one, another surgery question. Paula says, healing peptide differences. So when would you use VIP, KPV and VLON instead of BPC and TP 500? I think VIP and vlon would be more in like the systemic chronic issues like autoimmune, rheumatoid arthritis things. KP V going to work good in any situation, but for Vlon and VIP there are a little bit more VIP more on the inflammation,

31:41 Vlond more the immune side of things, So you could use those for healing, but it would be more like on the chronic healing mold type issues, autoimmune type, issues and things like that. Speaking of which, let's talk about some autoimmune issues. So John says, for thymosophil-1 for rheumatoid arthritis, when on a T cell biologic, can you use that? Yeah, I think you would be fine. Obviously you want to talk with your doctor, but I that would fine to use there. Brad says on TERS, GHK, BPC, NAD, CLO, MOTC, feel great but don't know which is working.

32:17 Yeah, I don't know what the question was there. Sorry, that one might not have got summarized right. Then he says autoimmune episode. I Chelsea says, alopecia, ariata, and scops psoriasis on clove, GHK topical, TA1, blends versus individuals, microdose, GLP instead of metformin. I would definitely say a micro dose of GLPs. You could still use met formin if you want to.

32:47 For the psoriasis, I will try topicle ivermectin in this case. It seems to work well. Could also try some topacle KPV to see if that works well in addition to the GH K. So those would be the first things that I wouldn't add on and see of those work. Let's see. Autoimmune protocols for lupus and RA. I think the standard answers are going to be thymus, nalphal-1, KPV, LL-37, thimalin. And in a lot of cases too, those people need hormone replacement.

33:17 People don't understand how many times someone has lUPUS, RA, MS, and a lotta times those are severely deficient in hormones. So the peptides obviously will be very beneficial, but I would say get your hormones checked as well. Recurring theme of today. I know it gets annoying when I talk about that, but I do always want to like, make sure I contextualize that around those things because hormones do so much. Uh, Dylan says that myself one for immune function, I just had a keloid removed. Does Thomas not for one cause fibrosis or am I confusing with TB four?

33:47 I think you are confusing what Thomas and beta four, it does not cause fibrosis. It would be anti-fibrotic in that case. So I would think both would beneficial in the case of a key load. Someone is all right. Let's talk about some cognitive issues. So Tammy says she's studying for an exam stack of C max length, a hexa and nine M E B C thoughts. I think those are all amazing. And I those will help a lot. Uh, the only thing you may want to add in is new pepped, but uh, I this could all be beneficial. Alyssa asked about Atomax, C-Max, or P-21, what each does.

34:20 So Atomex is kind of an enhanced version of CMAX. It's going to be a stronger version. P21 think about that as more of like a neuromodulator, so it's not going be an eutropic. I kind think of P 21, this is not chemically true, but I think it is like, a light version because to me it works very similar, um, just more like light versions of it. Um, and so that would be my recommendations there. Those are only cognitive ones, not too much on those. So about some cosmetic ones, which is not my area of expertise.

34:50 As always, I tell people to talk to my wife about that. And, uh, again, could use some help in that department too. So I do not claim to really know anything about cosmetic stuff, nor to be a walking billboard for those things. However, do my best to answer questions. Michael says, how to reverse growing hair. I will say me when I take oral and injectable GHK, it does seem too dark in my hair, especially because sometimes when they take my lan tan and my own, that can cause my hair to be a little bit lighter or get graze. So that would be my recommendation for that.

35:20 Causey says peptide for thinning hair for my sister can be, a lot of things in the case of a woman, it could be their thyroid function. It could, be uh, nutrient deficiency. Uh, could an androgen thing. And so my first thing that I tell people is get your thyroid checked. A lot times if the thyroid is slowed down, that could cause hair loss. If you're supporting the, thyroid with desiccated thyroid or thyroid by a regulator, That can, can very beneficial. Same thing if your hair is falling out on a GLP. A lot of times that's because the GLPs is shutting down thyroid function because you are starving yourself and you need to replace some of that to help

35:53 with hair loss. Sherry says a six year old female on red has started glow, wants to have a loose skin from 20 pound weight loss. Is there a peptide for a lose skin? Unfortunately there's not. And to go back to the question earlier about the skin removal surgery, in a lot of cases you might just have to cosmetic surgery to get rid of the excess skin. Laura says I got a melasma started after Melanotan 1 spread after a tanning salon visit. Why? I don't know why specifically this does happen in some people.

36:24 So this is why I say start with a really low dose of Melantan. See what it does. In some cases, glutathione does help with the melasma. I would recommend you could do a topical glutothione or injected glutethione, but it doesn't seem to help those. All right. Let's move on to some heart health questions. So Sasha asked for a stack for endothelial repair and blood pressure issues. I'd say a GLP is obviously going to help a lot with that. And SGLT2 is going help with a that and then I would say Vessagen will help.

36:58 That's the blood vessel bioregulator. ARA290 could be potentially beneficial and even BPC-TB500 could beneficial as well. Marlan says on Rizuvus statin for 25 years, I want alternatives. Turzin red are helping, but afraid to drop the staten. Well, obviously don't be afraid of drop this stat. And if you're hormonally optimized, if your taking desiccated thyroid, which also helps with lipid profiles and you taking GLP, those things are all you have to do. So you don' have fear not taking cholesterol medicine.

37:29 Then also too, you could take some citrus bergamot, a supplement. I would do that like 500 to 1000 milligrams per day and then go from there. You should be well on your way. Talk to a ton of people, that's what they do, their cholesterol is fine. Let's see. Peptides for heart disease in women, really the ones that I just talked about would be good there. Jade asked about POTS and MCAS post-COVID or long COVID, felt great on TERS, stack for Pots.

38:01 Issues, I think SS31 could be really beneficial for people with POS because there does seem to be some mitochondrial dysfunction there, and I would even say maybe a little bit of VIP too, All right. Let's see. Talk about some bone and joint health issues. So I get asked a lot about osteoporosis. I'm going to kind of combine all of these into this. A lot of people have osteoperosis, sarcopenia, muscle wasting, bone density issues, hormones almost always will help fix a growth hormone peptides do really

38:41 well in this category. We do see clinical data around increasing bone density with the growth of peptide. So I'd say that would be my next thing. And interestingly enough, VIP has actually been shown to help with bone intensity as well. I think that could be one that's potentially for someone that is suffering from osteoporosis that you could add in to escalate or expedite things to get healthier. All right. I get asked a lot. So I'm going to cross the section off.

39:11 Get asked about tinnitus and I will always be the first person to say, I don't know. Uh, when it comes to tennitus, is I have never seen one peptide that really is healed tannitis. Um, actually, and this is probably from having a ton of concussions. Sometimes I have a low level ringing in my ears. And so, um, tinnitus is one of those ones. If I knew a way to fix it, I would definitely talk about it. But I don't know that there's any peptide that really helps with tennitus. So unfortunately I know people have severe tannitis. Um, you could try cerebellitis and I've heard of people doing that.

39:41 Maybe it'll help. find a peptide to help with tinnitus, let me know. So I haven't tried one yet, but probably due to a lot of concussions I had when I was younger, that is something that not all the time, sometimes I do have ringing in my ears. I wouldn't say it's to the point of even really being noticeable a lotta times, it is just something I don't want to go tell people. Like I always just say, I could go make stuff up. Hey, go take BPC for tennitus or whatever and come up with some reasons why it would help, Do that.

40:14 And I never want to do that, but I just don't know of anything that actually helps with tinnitus, unfortunately. If I do, I'll tell you. So about thyroid health. I had a question. Is it okay to take thyroid bioregulator if on T3 and T4? I think so. You may not even need as a high dose after taking those. Definitely fine to use those, Believe I have underdiagnosed thyroid since starting RETA.

40:45 That is very common. And so I would say get your thyroid checked. If your free T3 is not over 3.5, then you probably need some thyroid support, especially if you were on Reta. There's this new compound called MA5 mitoconic acid. Is it best for mitochondria? I don't know. I will be looking more into that. So for all you researchers out there, get on it. Let's go find out about MA five and see if it's out. They're, I didn't even know if he can source it anywhere yet. What are your thoughts on rapamycin? I like rapomycin, I think it's age dependent.

41:15 I don't think anyone really needs it before their 50s or 60s. Uh, do you think you could do it once a week on a rest day to potentially improve, uh, longevity? But I also have so much out there now. that we might not need rapid myosin. I think if you look at SGLT2s with a GLP with metformin, you might need rapamycin on top of it, but I don't think it's harmful. For me, where I get kind of sketchy about it is that it does inhibit mTOR, and so if we're inhibiting mTor, obviously there's the potential that that could

41:48 suppress muscle. And I think when we look at longevity, we obviously want muscle for longevity. So that would be the reason I would tend to like have hesitation about it. But I will say there is evidence that rapamycin induces menstruation and ovulation again in menopausal mice. If you're an older woman, I could potentially be beneficial for fertility too, if you feel like that might be something that you or not the best with, if you are like in your forties and late fortys and still want to have children, that could potentially be an outlet or something that you could experiment with.

42:23 Phoebe asked if epitalon is okay and someone with type two diabetes. Yes, I think that is absolutely fine. It could be beneficial. Obviously you want a GLP, lifestyle change, but I'm thinking it'd be All right. Uh, is there a difference for matzi and dosing for males and females? I don't think so. I always just recommend people start with the lower dose of Matzi. And if you don' feel anything good, that's okay. You can always up the dose. But if start 5 milligrams or 10 milligrams, guess what? It might be too strong. you might have anaphylactic shock. might end up needing an EpiPen.

42:53 and you may have to go to the hospital. So always build up to those higher doses. Me personally, I dont go over one to two milligrams per day, but you want to over. to five milligrams or 10 milligrams, or whatever it is. And that's fine. If you want to do that, I personally don't. However, when you're starting out, please just start low because I've seen so many people have a bad response. So there's all the dosing of, Hey, you take five milligram three times a week or wherever. Totally fine if you wanna do, that I just personally know. All right, let's just move into some miscellaneous things.

43:29 B733 dosing, I like 300 or 600 micrograms. That is a peptide that seems to lower blood pressure and have anti-fibrotic effects. I've used it, can't say I felt anything different, but I did like it. It did seem to have an antiinflammatory effect when I used. So I do like B 733, very lesser known peptides, there is some data with it helping directly with blood-pressure and then being antifibrodic as well. All right. Dada as a pre-workout research suggests two to three times a week, not every session thoughts.

44:01 I think that's good. If you overdo it with DADA, you can potentially, one, just push yourself too hard. And then also two, I just think it's one of those things I like to cycle stuff. So do it two or three time per week but you don't need to do every day in my opinion. I would say Dada like, it makes me aggressive. It doesn't make me angry or anything, but it does make more aggressive in a workout sense. I don't get like angry, But I do get more agressive when I take Dara, which I think for a work out could be a good thing. Someone asked me about ACE167.

44:33 So ACE 167 is a drug that is an oral peptide that's being studied right now. I think it's in phase two human trials. None of the data that I could find is public on it, but there are research companies that are selling it. What you would take is like 2.5 to 5 milligrams per day of it In the rodent trials that we do have public data on, it increased cholesterol synthesis in the testes, which then doubled testosterone. So that would be pretty cool if it was doing the same thing in humans. But at this point, I just, we don't know what we, don' know.

45:04 And so I would love to see more people that have used it, tell me about it. I don''t need to use it and right now fertility is important to me. circumspect in that regard around my testes and what is going on down there. But if you're daring enough to go get it, I would love to hear your feedback on it and how it's working. I do know it is being studied in humans right now. We just don't know because the biotech company that is making it which I believe is the same one that made ACE031, which is a myostatin inhibitor,

45:35 and ACE083, which I've used them for, and those seem to work pretty well for myostatin inhibition. All right, just going through some of these miscellaneous ones. I always get asked about teens and peptides. We're actually going to talk about that on a Reader Mailbag episode, so stay tuned for that, that Taylor and I are going release very soon. Can you stack ters and reddit at microdoses? Yes, absolutely. Kelly says, peptide for prostate issues, I like one to two milligrams per day of Vesilute, V-E-S-I-L-U-T- E.

46:08 and one to two milligrams per day of Prostomax. I've actually used those just myself, and I don't have any prostate issues, but I will say my bladder flow and just overall how you feel when you urinate as a man was very much improved from doing those. So fortunately for me, PSA is really low, prostate volume, all that's good for when I had it measured. But I would say there was improved bladder-flow enhancement for those, so I think for guys that do have BPH or things of that nature,

46:38 Do two to three times per year that cycle of 30 days, one to two milligrams of Prostomax and Desolute, both per day. Works wonders. I love it. And I give it my thumbs up and plan on probably doing that at least once a year for me, even though I'm in my thirties. Jose asked if the NAD plus mod C5 amino blend is worth it for a 300 pound person on reddit or weight. Uh, yeah, I would say absolutely. In that case, you were probably going to vastly benefit from taking that. I will definitely add it onto the redditor. Just get normalized to the writer first, and then also understand that you probably are going have an increased heart rate from,

47:13 taking all those at the same time. So use it with caution and just be careful. This is a question I get asked all the time. Be good to talk about this here on the cheat sheet when it shows AM and PM. Does that mean twice a day or once? It's up to you. Actually, the top of the cheat sheet, which is on the newer one, so you can download the new one if you want. I just say, when it says AM slash PM, you could do them both or you just choose one. And so for instance, like a peptide that would have that with would be Tessamerelin.

47:44 So you do Tesamerelin AM and PM. You can do it only AM or only PM I'd say use your discretion, but if it's on there, it basically means you would do both if wanted to. Or you could choose one if you want to do. So just do what's ever convenient for you. But if it's on there, it is basically saying yes to both. I know that's annoying, but that my philosophy. And I wanted to be able to put that on. There should be like, Hey, you can do testimonial and you do it AM and PM AM or PM and choose. Um, Why is NAD plus the only peptide reconstituted at 100 milligrams per milliliter?

48:21 Well, I would do glutathione that as well, but N80 plus, because of the nature of it, a lot of times you need more water to dissolve it and then you do it. And it comes out to a hundred milligrams. Brian asks for my core stack of test, HGH thyroid metformin Jordians, RETA and SS31. Do you rotate any of those or year round? So the ones that rotate probably SS 31 with some matzi or some humanin, maybe the Reta like I'm trying Masdutat right now instead of Rete just to see how that does. But the test HGH thyroid and the met formin Jardians stay on those all year around.

48:53 So great question. I know Brian has been paying attention with a question like that. Blends like glow and clode do the peptides are great each other sometimes peptide two times a week, but blends force daily Yeah, so I made a video about this you can go look it up if you want to watch a 45 minute video About the science behind that but as it stands right now It does seem that Chloe and glow are fine together when you mix them in a vial And so i use those personally and have gotten great results Right just going through

49:27 some of these already talked about Let's see. That's why those says, uh, I would love to bring the message to us Hispanic audiences. Yeah. Feel free. I always tell people with my content, um, that's the best way to say this. So I want you to take my contact and share it, cut it up, share with other people. If you want to dub it into Spanish by all means, take that. Um, you know, it's interesting, just as, this is like a little philosophical tangent here.

50:02 back in the day, you had like Napster and Limewire and those things. And there was this huge fight over content. Like if you were a musician or whatever of like trying to keep the content gated and as we've transitioned, I kind of view, cause I was like a child of the early internet age, was born in 1993. So like I view content as like the more people that have access to my content, Like that's a good thing for me. Like it only is beneficial for. So if people are pirating my content, that actually makes me happy.

50:33 Now, do I want you to pirate my. No, I. Want you. But for instance, like, the way that I think of like when I'm writing books, Like I never write a book to make money on it. I write. To have people to basically have like a low cost way or a zero cost. Way to have access to the information for And in the newer economy, like if you look back to like LimeWire and Naps for those days, they were trying to prevent those companies from monetizing the content.

51:03 And obviously like that has gone away. We have like Spotify and iTunes and these things now and artists make monies in different ways. I'm not like a musician, but when it comes to my content, dub it, share it with people. Like I want my contents to be all over the internet, especially when you're someone that's the risk of being shut down. it constantly. Like I want my content shared all over the internet. So when it comes to my stuff, like feel free to do whatever with it. If you wanted to like share it on channels, do, whatever. I will say like, obviously like books, if you want to buy them on Amazon, support them.

51:33 But I know like my book. You can go on any of the book websites and download the PDF of my book. I don't care because I make hardly any money on my books because the royalties are so small. Like I want people to take it and then do with it. And then me as an entrepreneur, I will find ways to monetize my content that are not necessarily through people paying for my contents. So I think the best thing you can do is like someone that's a creator is just make content and put it out there. And then all of the goodwill will come back to you. If you're smart about how you monetize that, there are ways to do that.

52:03 For me, that is why I have my private group. So like all the content I put on the internet is out, and then I'll have content inside of my group that people pay for. Guess what? If someone really wanted to, they could probably take that content out of their group and pirate it and share it. But what they can't replace is the access to me inside of the private group. And so again, that's just my kind of philosophy. Maybe that'll evolve as AI and things like change the economy. Cause I think that something that we're up against, but anyway, long tangent, uh, yes, you do have my permission to dub it and share it with Hispanic audiences.

52:33 I used to speak Spanish pretty well. Definitely a little rusty, um, don't expect any Spanish videos coming soon because sometimes it's hard enough to pronounce all a lot of these peptide worlds or peptides words in the peptid world. Um, let's see, just going through, getting closer to the end here. Traveling with peptides, it stacks with them without check bags, not a plan when you can't bring them. Um I always check my peptide in my check bag and I usually always have a checkbag.

53:05 I know people bring it through TSA and they just tell them it's personal medication and the don't usually have issues, but I just don' like to risk it and most of the time I have check back anyway. Uh, Lori asked about reconstituting a hundred milligrams of GHK with one ML of backwater, the bottle too small. I like my GH K to be somewhere in the neighborhood of like 25 to 50 milligrams per milliliter.

53:36 And so, um, Even if you get it down to like 10 milligrams per milliliter, it's even a little bit better because it usually stings less. So just the thing to remember with GHK is like typically the more concentrated the peptide, more it is going to sting. GHk is usually lots, many times bigger in terms of the amount of peptides in the bottle. Like GH K is in a 50 to 100 milligram bottle, whereas like most peptides are in a 10 milligram bottle. And so the same amount of water is actually going to be a different concentration than most peptides and GHK by itself stings,

54:10 but it's concentrated. So it might sting even more. I like to dilute it down even in that case. Is a four millimeter, 32 gauge needle long enough for sub-Q? Yeah, I think so. I like a 31 gauge, like six millimeter. Yeah. That should be, W should fine for a sub Q. Filtering peptides, is it necessary? Is there damage from forcing it through a micron filter? As they're lost in the filter. I don't think it's necessary if you trust your supplier, but if it doesn't, it is a good idea.

54:40 Is there damage? I do not know. There may be, specifically. If there is some loss in the filter, yes, there will be some. So understand that you're not going to have as much because some does get lost in filter. Not the peptide concentration, the actual amount of peptides, you do lose some in a filter because it gets filtered through. In my opinion, I've done it before, and I also trust where I get mine from. Courtney asked for endotoxins and research peptides as glutathione help reduce them.

55:11 It potentially could reduce. Well, what it would do is it, would assist your body in eliminating and detoxifying against them, so I would say there's that. If you are worried about it. I personally am not worried, about endo toxins in mine, but I realized that that is a potential threat for a lot of people. Marcia asked about my updated take on hydrogen water. office fridge. Sorry, I went away from the mic. I know people do not like when I go away for the Mike got this little stuff right here.

55:43 It's called mind, body matrix, hydrogen rich water. Drink this throughout the day. Usually drink like three or four of those per day and I also like the hydrogen tabs. Um, there's a guy named Alex Tarnova or turnover. Forgive me, Alex. If I'm mispronouncing your last name, he's kind of like a godfather of, uh, molecular hydrogen. So he has got some, some good stuff if you look him up. But, um, yeah, love, Clean Omega 3 brand. I think I use Wild Alaskan Peak EPA, peak fish oil, I get it from Sprouts and Amazon.

56:18 It comes in an amber bottle. Seems to be working pretty good. Jen asked about a healthy vape mentioned on the show. So I've been using a carbon 60. I guess it's a vaPE pen. It's kind of just like a little inhaler. Has carbon-60 ATP and glutathione in it. But I really liked that. If I do that like 30 minutes before cardio and do cardio, it feels like I'm just coasting through my cardio. So I think that's called Nano Genesis Labs. I don't have an affiliate code, unfortunately, I probably should. But I really like that stuff. Just picked it up at A4M this spring. Works pretty cool.

56:48 Still take C60 though, from shopc60.com. Do have a code there, 110. Love Carbon 60, but it's cool, so you can just hit that pen before cardio. And it doesn't seem to have like negative lung effects or anything, because it's just like a little water droplet inhaler. So you can inhale it through the pen, then blow it out through your nose. But it does work well. And I love that. Then lastly, someone recommended that I use 11Labs to calm my voice for reading my book. which I am looking into now. And so hopefully for my new book that I'm working on and even my old book to which, I do not have an audio book released yet.

57:22 It's actually funny because Amazon sent me an email and they're like, Hey, do you want to use our AI voice colon? I don't think it's 11 labs that Amazon uses. Maybe it was built on their engine or something. But they just, as an author, they sent. uh, because they saw that my Kindle book and my paperback was not inaudible, that they did have AI voice stuff now. So for the sake of time and brevity, I probably will do that just because the AI voices are pretty good and you can actually clone your own. And, um, the more time I would spend recording my books is the less time that I could spend, recording videos. I'm kind of in a catch 22 of like, Hey, yeah, could do, but then it also too.

57:54 There's only so many hours in the day, doing that. And if it's 90% is good for me, that would be worth it just to be able to have more people exposed. Cause there are certain people that will only listen to the audio Burke version and not read it. So that is it for this Q and a made it through all those videos as always. Thank you guys so much. I didn't look at that we're right in our. Thank you guys so much. These are awesome. The fact that I get this many questions and I have to condense them down and sort and filter through is amazing. And hopefully you, guys enjoy this watching it as much as I enjoy making them.

58:26 But as always keep submitting those questions. I do have that AI chat tool now. So hopefully that thing is learning on the content and training and getting even better because it's supposed to improve upon itself. But thank you guys so much. Just in closing, like the fact that I get to do this is a dream come true for me. So love each and every one of you, guys. Thank you for all the support, whether it's sharing this content, using my codes at places, being on the email list, be inside my private group. It goes so further than you know in helping me, so thank guys, I'll see you in the next one and we'll be back in some more videos and then another Q&A

58:59 next month in June. Peace.