Saturday Morning Coffee Talk · 1/17/26

0:00 I don't know. Good Saturday morning, everybody. I hope you're doing well. And I see that there's we've already got some comments coming in. So that's awesome. We'll wait. Wait a couple of seconds as people start to come in, I know it takes a second. Oh, wait, maybe Jen. Why is it? Is there is there an echo? There was a minute ago. It could have just been a computer.

0:31 That's weird. I don't know why it's doing that. Let me see if I can fix it. Test. Testing. Okay, I think maybe. 20 to mute. Um, we might have, she might've to put headphones on.

1:03 I think what's happening is that her mic is picking up our, um, the feedback. And so it's like coming in a couple seconds later. Oh, let's see. Sorry, everyone. We got some technical technical difficulties. Are you hearing an echo Jen? No, I'm not. But I just tried to mute myself. So when I can mute my self again and you can see if you're still hearing an echo.

1:33 Oh no, we're hearing it echo back from her now. I have no idea what is going on. It's not doing it to you though, right? No. Could it be because we are using two mics? It might be. Should we just take my mic out and just use yours? You could try. Try this now. Let me see if it echoes. I think it's still doing it.

2:07 That's crazy. Well, the good thing is no one else is saying it's echoed, but like when we're talking, I'm literally hearing myself back to the speakers.

2:43 What if I just, then we'll not be able to hear Jen. It's the problem. Let me refresh it real quick. We might disappear for a second and come back in.

3:21 All right, we're going to try this again. Still doing it. Sorry, I know everyone, but I'm not going be able to hear because it's like coming back at me of my voice while I am talking is like, coming through my speakers. Maybe if I change the speaker. Let's try Still doing it.

4:03 That's weird because I changed the Mac broke and it's still going through the actual speaker. So doing it now.

4:34 Still doing that even through the other speaker. It's not that bad though. Yeah, but we're not hearing everything. Still doing it.

5:06 Jen, say something and see if it echoes when you talk. Good morning, everyone. I'm not hearing an echo. Yeah, even hers is hers. It's like a delay. So it's, like, saying exactly the same thing over. Right away. Would it help if I joined via the YouTube link and then you could Enter me in that way, or does it have to be through the live stream link that you sent? Would that make a difference?

5:36 Well, it's the same link. It's going to. The same type of setup. Yeah. I have no idea why it is doing that. And you don't think like earphones would help? That might help. Are you, are you on the live stream too? Like, did you join the livestream or just just, no, just the link that you sent me.

6:09 Okay. I have no idea why I was doing that. Do you want to try just unplugging my mic and seeing if it does it? No, cause I switched, I switch your mic. Maybe unplug that, Is it doing it now?

6:39 It still is. Oh, let's see. Sorry, everybody. If you came on, there's something wrong with our audio that's like seriously messing up.

7:17 Let's try one more time. Still doing it. Oh my goodness. If you would like, I can just go. off of here and just join the regular, and maybe once we can figure out the audio difficulties. The problem is, I think even if I were, let me remove you for a second and see if it does it.

7:50 Okay. I still think it's still gonna do it? Yeah. All right. Am I gonna hear myself back when I say something now? That is crazy. Absolutely.

8:29 Oh, there was a tab open. Let me see if this better. Okay, I think we got it figured out finally. Yeah, plug that back in. I Think we figured it out. What was happening is the YouTube was open as a tab on the computer in the background.

9:04 And so it was playing that. That's why it's coming through later. So that's what I was not echoing for anyone else but us. I didn't realize that the tab was opened in We're good to go now after after 13 minutes of technical difficulty. So we should be good. Thank you for coming on this morning, everybody. We can have a fun one today. we actually have Jen Seeger from our group and she's a co-host inside of our private group. And she is awesome, but just want to have her hang out this.

9:35 She's really smart. Knows a bunch of stuff about biohacking. So I think she will be a valuable addition to the call. And then like, if there's any questions you guys have for her, obviously, I thing it'd be fun too. But before we get going into the questions, I think rant wise, my only rant for this morning is it's crazy how many doctors will prescribe women estrogen and progesterone before they give them testosterone or they'll give him testosterone and estrogen at the same time.

10:07 And I just keep seeing a lot of women struggle with. an overload of testosterone and estrogen starting at the same time. And then they ended up feeling good or just not feeling and then ended going off of their hormones. So that was the, the mini rant that I had for this morning is I think the best progression for women's hormones is to go from doing testosterone and progesterone first,

10:37 wherever you're at. And I think if you pair your post-menopausal, then you can layer in estrogen after once you feel good and then have kind of found a sweet spot and want to improve. But I've just heard so many women recently starting on estrogen and Progesteron first and having a really bad issue once they introduce testosterone after doing the estrogen. So I don't know if guys have thoughts on that. Obviously you are women so you know better than me. Yeah. I agree. I mean, it shows the importance of introducing one thing at a time.

11:08 So you know how you're reacting to each thing and you give your body a chance to adapt and then kind of know what you are feeling and how your functioning. But when you throw everything in at once, its really hard to kind to discriminate how are you reacting each one. so I think that's a great point. Jen, what are your thoughts with having the medical background? And for those of you who don't know, Jen does have her doctorates in nursing and whatnot. So from just coming from a medical back ground, where do you think the missing piece is?

11:43 Do you it's more so a lack of education with the providers? Why do think it is such a common thing to see prescribers do medications this way where they're doing the estrogen and progesterone and then testosterone later when we know the benefits of doing testosterone first and introducing estradiol. I think some of it is a lot of, it may depend on the experience of the prescriber.

12:13 I, think perhaps the more seasoned prescribing are not used to really women needing testosterone or that really wasn't like a common practice. 25 years ago, once you get in your 50s, having sexual vitality and energy and motivation that's just gonna kind of Wayne as you you know as your progressing in your age but I think as the research is shown really just what a game changer it is and I thank in terms of estrogen you back in the seventies.

12:47 when they weren't using the bioidentical as much, you know, there was the whole myth about the certain word. We don't want to say that, if you started estrogen therapy, that you what the side effects were going to be. And so I just, I think that it wasn't as talked about. I don' think it was part of the full picture, the ful spectrum. It was more, let's treat whatever disease you have instead of let' prevent. aging and decline in your vitality. But I think that there's more providers getting on board. You're seeing a lot more stand-up clinics that a lotta the physicians and APRNs are leaving traditional medicine to open up these clinics,

13:25 that are addressing not just longevity, but just hormones, and really optimizing women so that, you know, they have an edge again, in that they don't have to feel like they to decline as we age. Do you think, so my thoughts around the thing with estradiol too is when you raise estridiol with low testosterone, that could actually make someone feel worse than they had just never done it at all.

13:56 Because now you have the presence of, like the body doesn't naturally do that. Like the, body, doesn' just raise, estrdiol without raising testosterone. Especially in a woman's body. Obviously we have testosterone that, uh, aromatizes into estradiol, but then you have like, it's a woman it produced in the ovaries as well. So I think it just even a weird situation to put people in because you're just overloading with estrdiol. No testosterone. And if you look at like a hormone profile, there would obviously be a ratio to which probably everyone's little bit different that that would like like

14:27 the body would figure out to do. Then you just skyrocket estridiol It would put someone I think like in a really emotional state to like where there may be like having weird, uh, emotions like anxiety or something like that. And then maybe even weird symptoms like hot flashes or if they're like estradiol is too high without testosterone. That in some cases, some women will either even like, even if their postmenopausal and if there are very early post menopause, I've had some woman that have started estridiol and then they start getting breakthrough bleeding.

14:59 Hmm. as well too. But you're saying that wouldn't happen with the testosterone. Is that because the testosterone is super low or the estrogen is just so high? I think that the estrogens too high because that's actually one of the symptoms of estrogen being too and it's usually because if they're already on testosterone, they are converting testosterone into estradiol and then you add estrdiol in there aswell too, that is one symptoms that we are told at World Link that that when estridiol is dose too breakthrough leading can start happening.

15:32 Jen, do you think that a woman's body fat levels, especially if they're peri or postmenopausal, will have to do or not, whether they need to supplement with estradiol, meaning that if a women is really lean, she probably will end up needing estrdiol once she gets her testosterone down then, versus if her body fats a little bit higher, She might just aromatize enough because she'll have enough aromatase expression because her I can use myself as an example and then kind of a different example with other women that I've worked with.

16:04 So when I started testosterone, instead of aromatizing estrogen, my estrogen fell to almost the level you couldn't even pick up in lab. And being very lean, it just plummeted. And so that really surprised me and I didn't really have symptomatology initially, probably the first couple of months, but then I was like, something's off turns of my cognition and how I, was feeling. So I did give blood work and then that's a conversation with my provider about, okay, this is what I need.

16:36 Then I've seen other women that maybe they're just on their journey with fat burning and health optimization and they have higher body fat levels. Usually I see those types of women, they are aromatizing more and then their estrogen level actually is raising. So definitely you can see these two extremes. It doesn't mean it's going to happen, but I think that's where the importance is, is knowing what the symptoms are and also getting the blood work to kind of substantiate what you're feeling and what your suspecting.

17:06 Yeah, I think as far as trends go, we're going to see millions and millions of more people in the next decade, especially women start to go on hormone therapy. And my hope and my mission is to educate people so that when they do go to their doctor, because all doctors are different, just like if you went to a lawyer or a mechanic or dentist, they're gonna have differences of opinion. Did all women go to them and say, Hey, I want to optimize my testosterone first and then later in the estradiol if needed after that.

17:36 And I think progesterone is pretty much just a standard of care. Like that, that would be like something that you would just do for all. Women kind of regardless of age, but hopefully the market and we can help educate the of like, women should go in thinking testosterone and actually like ask them for their doctor. If the doctor is against that and they just want a prescribed estridiol and projesterone, then probably look for a new doctor. Cause there's so much data that we have even clinical literature to show that that's better to do. Um, but just from what I've seen in the last couple of years of, you know, women doing well with Jen, what are, What advice would you give?

18:12 Like some of the women that are listening to this coming just like a medical background of like they're the best way to approach their medical provider for wanting to get hormones. Like, is there certain questions that, that you think is helpful for them to have and ask? I think the first thing is for everyone to remember that the providers work for you. And so I if you go into that mindset, and that will help you embrace confidence, because it's your body.

18:43 So you're not going to respond like everyone else. You know what's best for. If you going with that mind set, this provider is working for you. And so if that is not a right fit for, you that you want to find other providers. So it's a matter of being on platforms like this, listening to Taylor and Hunter to educate yourself and know what the symptoms are. Do the research on the why of testosterone, what effects of Testosterone are supposed to be, and then compare to how you feel on that spectrum.

19:15 If it is the motivation hormone, how is your motivation compared to 10 or 15 years ago and then research what progesterone is supposed to do and how are you feeling on that spectrum and the same with estrogen. So going in there because you know your body, you Know your history, You know when you felt your best and you also know how you want to feel and and by researching how You should feel so I think if you go in and if You're getting pushed back then maybe that's not the right person for you to work with.

19:45 But arm yourself with the knowledge you're in the place and have that confidence to know it's your body and that they're working for. And yes, of course, providers, they went through training, but some of them, maybe they already have a bias against hormones. So you'll be able to filter them out and find someone that is going to be more supportive of that. It's All right, let's get into some questions and I'm going to make sure I put them all up on the screen and we will start to rock and roll.

20:18 So guys, go ahead and start. If you want to go and started dropping the questions, we'll make that we answer them. Sorry for the technical difficulties. It was actually a fault on our end. We had the tab. I didn't realize that the YouTube tab was open with the link. From where I'd copied it into my email before and it was like playing feedback for so anyway. First question we need to know how to dose five amino injectable five Amino I would say start with around one milligram and then you can kind of go from there.

20:48 I actually just started doing a little bit this week. I haven't taken any in probably a month or two. And I do one milligram, and I feel amazing. Like, I fell the effects from it right away. I've heard other people say they take 10 milligrams of injectable 5-amino or even 50 milligrams. If you can afford it and you feel good doing that, knock yourself out. I would recommend starting with one milligram injected sub-Q. You could also do it IM if you wanted to hit a little bit harder.

21:21 But I like one milligrams to start and then you go up from there. If you need more, you can. I don't need to me. That gives me plenty of energy for the day. Uh, I would ask you guys like from a women's, uh, woman's side, do you think the dosing for women is any different? Do you thing that's about the same? I feel like it's really depends. It depends on the individual. And I think it could be the thing because even just taking one milligram of five amino, like first starting, in the morning, if you've cycled back off of it and you just started it back in, like I'd been off that for a while and I just cyled it in this week.

21:57 And I noticed that like, you can, I can get a little hypo. I think that probably was from more from the Matzi, but you still could from The Five Amino. Yeah. Just kidding. Nevermind. Well, it's true. Cause a lot of people take them both. You can mix them. The same syringe and they've done fine. together. So yeah, I think the Matzi is more proclivity to do hypo, but I you know, depending on how insulin sensitive the five amino is going to help with insulin sensitivity.

22:27 Yeah, you I think two, what I've noticed for lean people, five amino, especially the injectable one, it seems to work really well for like stubborn fat areas. Like it seem to help with some of that stubborn, fat tissue, and especially in someone that's already kind of lean but just wants to get it there. So again, play with the dose, but that would be my recommendation. And as always, we have all this information on the cheat sheet, which is a good thing. Jen, do you have any thoughts on that? I feel great with one milligram.

22:57 So I personally love it. I can feel a difference. Sometimes when I first started, I was only doing 500 micrograms, but I felt really solid. One milligram, and I do actually inject it, IM. Yeah. I think it's great. You probably get more of the performance enhancement benefit if you do it before a workout, whether like cardio or strength training, if do at IM. It's a personal preference. Sometimes with the MOTC, I like to do that sub-Q because if I do an IM, like I get pretty hypo.

23:28 So I'll get like lightheaded and kind of dizzy when I'm working out, especially if haven't had that many carbs in the morning when working But yeah, I think IM can be a good way to go, especially to enhance the performance side of things from that job. I love 5-amino. You know, what's interesting too is when I've used the oral in the past, the world dosing is like 50 to 150 milligrams a day. you probably go higher, but it just becomes really expensive because it's pretty expensive. to source, but the oral seems to really stop working after four weeks, whereas I noticed pretty good effects.

24:04 I don't seem to see the benefits decrease over time with the injectable. Now, does that mean like after six months that it wouldn't? I dont know, because I've never used it continuously for that long. But I do think the the oral you seem to just get like a tolerance build up to it. Where's the injectable? I don't I Don't necessarily think it's something you have to cycle off of and especially with it being a small molecule. It's not a peptide I think you get the same like immunogenicity to as you would a Peptide like mozzie, you know What's up Jim Jim is definitely caller

24:41 number one. Mm-hmm He says, do you think Carterine has a place in the longevity world or should be avoided? Personally found benefits of 10 to 20 milligram pre-workout. One of your thoughts. It's funny, Jim, I actually was going to publish a video yesterday on Carterin and I ended up doing the one on the glow and clow of just that those blends being, they are efficacious when mixed together. So I'm actually going release a good timing next week on Carterine. Did I finish? But yes, it actually has place on longevity. I would say For just longevity purposes, if you wanted the lipid profile improvement, I think the dose is actually even lower.

25:13 I would say five milligrams a day would be just for the longevity benefits. For the performance side of things, 10 milligrams is great. Then if the bodybuilder like elite dose would be 20 milligrams. And after that, we do have some evidence to suggest it could be favorable towards cancer, but there's also eight studies that show that it is anti-cancer. So it's one of those things, if you do you have animal data, it only animal, data it not human data that shows that could it be favorable to tumor growth

25:48 in some cases. It's just one those thing that I wouldn't want to use like 50 milligrams a day long term. I think 10mg is my sweet spot. That's what I take when I use it. 10 mg is good. If you wanted to, you could go up to 20mgs. But obviously, with that being said, I'm a fan of cycling that on and off. So if you want to do 8 weeks on, 8-weeks off or 4 weeks, on 4- weeks off, it's just one of the ones that I would be a little bit more stringent in the cycling of because there is some of that data. I'm not afraid of it though. So I would do that. But I think for the longevity side of things, you could even do five milligrams a day and see improvements and lipid profiles.

26:22 And that's what's interesting is, yeah, there's a conspiracy around Carterine. It was like on track to become an approved drug. Like it was, everything was going great. it's going to great and I. Think what they saw, it a PPAR Delta agonist and what the saw was that It was going to basically put statins out of business and there was already a lot of this was like late 90s, early 2000s. Statins obviously are big now, but that was those were up and coming and they kind of saw that as a cannibalization of the sales of statin because of what

26:52 it would have done for people's cholesterol. And as we know, does Carterine really have a downside other than maybe we have some of this data in rodents that shows that it was like causing tumors at super high doses. So I don't know. It's one of those things. Like if you get into conspiracy, Carterin absolutely will improve lipid profiles, it lowers LDL, raises HDL. And I think for those benefits, you could probably even get, You would see that in blood work at like five milligrams a day.

27:22 Do you like Cartering? I like it for cardio days. I don't like, it can make me a little overly hot when I'm lifting and I I have in the past, it's funny that this was brought up because I was reading about it and doesn't it also have a positive effect on cardiac output in terms of the efficiency of with each pump of your heart? So I would think it could almost be like a performance enhancer for people that, you know, doing more cardio intensive.

27:56 Types of exercises or workouts, so I have used it in the past at a lower dose. Like you were talking about the 5 to 10 milligrams, but definitely I know that it's supposed to have a benefit on the cardiac output as well, which we all could benefit from that. Yeah. Yeah, a lot of the cyclists got popped for it, because it is a banned drug, cause it works so well for endurance. I wouldn't say it's going to make you stronger, but you definitely, if you, take 10 milligrams of Carterine and then immediately go on a bike or elliptical

28:28 or treadmill. It's pretty fun because you can just go and you just don't really get tired, which is nice if your doing cardio. Let's see. So great, great question, Jim. Victor says currently on TRT 34 took a sperm test results were very low. What to do to improve them? Funny you should ask, this is what I am working on right now as well. So definitely HCG, HMG FSH are all great to take. If you're doing H-M-G you probably don't need F-S-H because it does have F SH in it, but you could add in bioidentical F S- H if you can source it.

29:04 I would also say in addition to those things, so dosing wise, like what am doing is three times a week I'm doing 1000 I-U's of HC- G and three time a we come doing 75 I use of H M G. Two times a week, I'm doing 200 milligrams of glutathione. And four times per week I am doing 600 milligrams L-carnitine. Those right there are usually what would be like the fertility stack. One thing that I actually learned from Alex Kickle was to add in FOXO4.

29:35 So what we're going to do is both Taylor and I will add FOxO 4 DRI at one milligram a day for 10 days and just run that for a cycle of 10 days, and then epitalon at the same time, one milligram a day for 10 day, just to help with the DNA parameters around the sperm, because that has been shown to helps with DNA makeup of the sperms. And so that's my fertility stack right there for anyone that cares to know it. But yes, Victor, I would add those in. So you're on the right track. I will just add in a couple of those other things and give it at least a few months.

30:07 It's not going to be one of these things, even though we would like it to. Whereas like in two weeks, your sperm is going to be fully modal and volume is gonna be full and everything. But if you give it a couple months, you should see some improvements. Yeah, he said he was a patient of transcendent stepping away. What's up, Kelly? How you doing this morning? Another North Carolinian. She says, got my IGF tested and was still only 120 with 10 IU dose. Wow. But should I be taking breaks? I mean, I don't necessarily think you need to take breaks from growth hormone itself.

30:40 That seems weird that it would be that low with a 10-IU dose. I dunno the timing of when you got it tested, but that's interesting that you would do 10 IUs. Usually like if you wanted to test if your growth hormones was legit, what you do is you take 10 IU's intramuscularly and then like two hours go to the lab and get your blood drawn. And then you would usually see like a spike in IGF-1, but that's where they would be low. But then also too, I've heard of other people taking huge doses of growth hormone and it doesn't really push their IGFS past 300. So I wonder in some cases,

31:19 this is rampant speculation, But I wondered in cases the body almost has a self-limiting regulation on the amount of IGFX gets converted out of the growth hormones. Now, I don't know, some people may be different. Some people just may metabolize it different, Some People based on age and liver function and estradiol. Estradiola actually can affect the conversion of HGH into IGF-1. And so estridiol can actually, if your estrdiol levels are too low, it can, actually affect how much the liver converts. So I dunno, It's one of those things, but in terms of taking breaks, i do five days on two days off with my growth hormone and I do that pretty much year round.

31:54 I Don't think there's any reason to take a break, especially if you're And in it for longevity and in your, you know, fifties or sixties, I think there's only benefit to doing it all the time. I mean, You could take a break, but it's kind of one of those things. It's like, have you taken a brake from growth hormones? Like taking a brain from coffee? It like maybe it is good to take break if you're doing too much of it. But you just realize if he take it to my brain for coffee, he just missed out on a little bit of enjoyment for the day. So I don't know. What do you think, Jen? I'm curious, Kelly, if you're having any side effects from that high of a dose, are you having an edema or swelling, holding excess water,

32:32 or are your joints sore? Is it a reliable source of HGH that you are getting? I mean, those are some of the questions, but I think that's a pretty high dose. But I am in my 50s, I still do five days on of HDH, and then I take the weekends, two days off. So every now and then I have done seven days on it just depends kind of on the time of the year and what my you know what's coming up you now what going on at work how my sleep but usually sorry that's my dog usually take a five day on a two day break in the weekends.

33:12 in that fertility stack. Growth hormone would be a piece of that. I'm actually increasing my growth hormone before I use a night just for fertility, because that does help with a little bit of fertility. And I won't do that for the long term, but just in the short term and it seems to work. It's crazy, like just even going up to four IUs, I actually have not been bloated from it, and because I usually do two Ius, But also too, it just makes your sleep so much better. Yeah. Remember that time I was accidentally taking like 12 values?

33:45 Yeah, you were sleeping like a baby. I'm sleeping so good. And then you woke up, then he woke three days later and looked like the Michelin man. You're like, what's going on? It is like if you do do that though, like water comes off pretty fast. Give yourself a couple of days. Well, yeah. Brenda says, I've been hearing conflicting information about injecting clove at the same time as SS-31MOTC as it can cause red bumps, rashes, not just the injection site, but anywhere on the body.

34:15 I don't see any issue with doing that now. What you may have is you have a red bump or a reaction from the GHK. Or you may have a lot of people get a reaction from Matzi as well. Now, does that mean that like injecting the clove with the SS-31 or Matzzi is causing that? No, I think independently that's probably happening. And so to me, that is more, one the GHK that just going to happen. That's a byproduct of GHk for pretty much everyone. with the exception of a few people.

34:45 So that's like the majority of people are going to have that from GHK. MotC, maybe 10 to 20% of the people have the reaction. I think that is more of an immune reaction, that probably something with their immune system going on. But no, I see no reason why you can't. Now I personally wouldn't mix the Mot C in the same syringe as like, the CLO, or the SS31 in same the syringes as the ClO. You could probably do SS 31 and Mot-C. There are blends that come pre-lyophilized like that, so those are probably okay. To do but I wouldn't put all those like in a shotgun and blast it But I don't think there's anything wrong with injecting like if you did in the morning

35:21 Chloe on one side Mozi or SS 31 or both of them on the other side. That should be fine Any thoughts good Yeah, that we're seeing everyone saying that here is it was actually our fault. It wasn't, it wasn' that user error. All right. Spanda says we'll combining exogenous GH in the morning with peptides like test morelin or CJC epimerelin evening, shut down natural GH pulses or is this

35:51 combo redundant? No, It won't shut. Down. I mean, of course, exogenous HGH is always going to shut, but the body's pretty resilient. And so most people can recover their function even within a week or two. at the worst when they use exogenous GH. And then obviously the peptides are not going to shut down your natural production. They're just going increase what is already there. Now is the combo redundant? I don't think it is, but I wouldn't do that all the time. I would just say like, okay, is there a specific use case? So for instance, like a guy might run to run Tessamerelin to burn some extra belly fat.

36:25 So he could take Tesamerelin at night and then do HGH in the morning and get really good results. Also too, what works really well is if you take the Testameralin get up, take your HGH and do cardio right after that. That's really like you'll fasted cardio in that manner. Usually you get a lot of bang for your buck out of that, you could do the same thing with CJC and Ipamrelin or Tessamrelin and Imamrellin together. But I don't think the combos were done to it. It just be would want to be the one of those things like he would cycle on and cycle off. I wouldn't do that continuously all the time.

36:55 Not because I think it's bad, but I just don' see the use case of necessarily doing it all th time like that I agree. Yeah. Jim says, as we've gotten older, everyone's strength training has changed. How's your change of you've got an older? I'll give my two cents and I let Jen Taylor talk. I will say I went much more from being a very heavy lifter when I was younger, where I could lift a lot of weight, especially when was a football player

37:25 to transitioning to being much in the neighborhood of like doing 60% of my one rep max for reps in like the 15 to 25 rep range. And I will say, you know what's interesting is like if I ever do want to like push weight, now I don't back squat like 600 pounds or bench 400 like I used to. However, in doing lower weight with more reps, it still maintains strength. So like, I still can do things like pretty strong. I'm not going to put myself in a position where I am like lifting that heavy anymore.

37:57 But it's, interesting how the body will just maintain a lot of that strength even just from doing lighter weight. to I was training with my brother over the holiday and you know, he's a football player and so he is stronger than me, but I could, I, was hanging with them. We were doing, you, know ISO squats with I think like it would have been five plates on each side. So what's that like 450 plus the bar. Or so probably somewhere around 500. And now granted that's not like a free barbell back squat, But you knew he was stronger.

38:28 He was moving it easier than, me. But I still repping it and I don't really go heavy on stuff like that. I will say I have transitioned more from being a heavier, go heavy or go home type person to being much more lighter controlled, contracting, focusing on the muscle contraction. And I think for the purpose of longevity, that's kind of where you want to be maintaining muscle. I'm not necessarily concerned with my max on anything for sure, but it's interesting. My joints feel better now from having peptides and stuff than they do when I was younger and I did all that heavy stuff and didn't have peptide.

39:00 obviously competing in a sport, but I feel great. I think a lot of people, if you're doing it smart and you have access to peptides, you are using peptide intelligently and your training intelligentially, uh, You can feel better in your fifties than a lotta people did in their twenties. Yeah, I would just say for me, that I used to be a very heavy lifter. So I'd go in and hip thrust like a ton of weight more than what I should have been doing. And now that the other thing too is that I didn't like do proper splits.

39:32 Like I probably would go in and like hip through us and do my legs like four times a week. which I did grow my glutes very quickly doing that, but knowing that I know now, like I never prioritize chest, never prioritized my back or triceps or biceps, my upper, basically all my body. I was just so focused on like legs and abs. And now that i'm older, I now understand the like prioritizing and really splitting up my muscle groups more.

40:03 Jen, i'd love to hear your, your your experience with this, because I just, I know you're like your whole background of being an athlete. Because you know I'm old, is that why? No, it's because i know your background being a athlete, you grew up an athletes and you did many different things. It's a lot less ego lifting now. So I used to do, even though I'm a small woman, very heavy lifting. I use to a lot of CrossFit style lifting and a a of the heavy compound movements.

40:35 And now I definitely have switched that up to more positive muscle failure, full body workouts, three days a week, a lots more mind muscle connection, like really focusing on the squeeze, not forcing reps. you know, being more connected and present during my lifts. And then if I have like a lagging body part or something I want to spend more attention on, that will be a designated lift day just on that body, whether it's like glutes or hamstrings, quads, but definitely a lot more of primary muscle failure, not doing as much of the multiple,

41:16 multiple sets, just a lots more trying to get to failure. Because I think what happened when I was younger is I would lift six days a week and the strain that that puts on your central nervous system and then you wonder why you're not recovering or why your exhausted. Or you know why you're so I guess kind of like frazzled and stressed out and another thing that I definitely have changed to with my lifting is my mindset around intro workout supplements and carbohydrates definitely will will help my lifts not necessarily that i have to go heavy but it helps me really be

41:55 more focused and get that squeeze as well. So that's something that I have adopted more as I've aged is, you know, to make sure that i have my carbs before and during my lifts. Yeah, I think nutrition also has been a big one for me too is adding more carbs. And especially like, i think about like when i used to lift in my 20s. I was like paleo and keto fish. I didn't even really eat carbs.

42:25 Now that I do eat carb, I've seen a huge improvement with my lifts from that. That's a very good point about the nutrition. I think for the nature of muscle building, you don't want to get into preaching about diet. Diet becomes a religious conversation for most people, but without trying to preach, I think, let's just say, lets just talk about like the nutrition for the workout. I Think pre, intra and post workout carbs are a necessity.

42:56 And then we can debate about the rest of the day. But I, think if you have a three hour window of, the work out of one hour pre one, hour during one our app for, workout the body does so much better when there are carbohydrates involved in that process. and then the, rest is up for debate. Like, you know, like should we be paleo, keto, carnivore during those times? There's a lot of debate about that. I'm not gonna like I I just think you should have a balanced diet But I do think for the purpose of the workout people respond so much better in the long

43:27 run For everything reproductive hormones thyroid hormones all of those do better around training when there's carbohydrates involved so I would like to hear if anyone that is using low dose naltrexone has any allergic reactions to their peptides. obviously give it like a couple of weeks for you to be on low dose naltrexone. VIP I have seen also seem to help as well.

43:59 KPV, I think what that is, is like the immune system telling the body, we don't like whatever is here. And I with the Tessa and the CJC, those are growth hormone releasing hormones, which means they increase endogenous production in a slightly different way than ipamerelin does. Ipamerelin is a ghrelin agonist, a growth hormonal releasing peptide. And so that could just mean for you for those pathways, there's some sort of immune reaction happening. when those pathways are activated, I would love to see anyone out there take the Pepsi challenge of using low dose naltrexone,

44:33 and then see if you have an immune reaction to your peptides. I have yet to find someone that has taken that and is also having immune reactions at the same time, once they've built up to using the LDN for a while. But it could just be for the person that, because CJC and Tessa are analogous in terms of the pathways that they work on, whereas IPA is different. That's why I always tell people too, if you're starting out, IPAs usually like a good start because it just seems that people just don't seem to have the reactions that have to the GHRHs.

45:04 But that would be my thoughts. Just look at that. I agree. Yeah, I think the low dose nitroxone is huge for peptides and the immunogenicity conversation around peptide. Let's see. Boston Sean says protocol, not for fertility, but for tests, testicular after atrophy after years of TRT only used HGT a few times can actually be reversed. Yeah, absolutely.

45:34 I think for the, the testicular atrophied conversation, I take HCG at like two 50 I use three times per week usually is enough, But it's just going to be one of those things like you, it not going come back right away. It's going probably be at least a month or two before it really reverses. But yeah, I think HCG could be good. I mean, if you wanted to do in Clomophene, you could. And I don't think in clomaphene is a long term solution, but it could maybe kickstart things. If you did in and HCT together, You could probably kick start things out of the gate to feel more that way.

46:05 Yeah, that absolutely can be. Even for someone if they've been on TRT for decades, they could do that and probably get some natural function back. Let's see. B. Perry says, started on clow in an attempt to repair atrophy subscap tendon before shoulder replacement. What would be a good option after eight week on Clow and Tessamerelin? Meaning I guess before a shoulder or placement, I think this is after the shoulder placement.

46:37 If I'm reading that correctly. I would say stay on it until you're completely recovered. Yeah. Especially with GHK. With GH K in there, you really want to stay in that until your completely recovered because of the cartilage repair that happens with it. Jen, do you have any thoughts on that? Actually, next week, somebody that I'm working with is getting a complete shoulder replacement, and this is exactly what I am having him do. So I would continue on until you are completely healed and went through your rehab and things like that.

47:10 Absolutely. Stay on it! Yeah. I would also add in too, if you did the Clo plus Cardalax plus PEGMGF, I mean, If you have all of those things in together, that is so powerful. People, Clo in itself is really good. But I think people don't realize the power of Cardalax and PGMGF in addition to it. I mean, I was having some pain in my hand this week, probably from playing guitar because Taylor got me a guitar for Christmas.

47:45 And so I've been playing that more and my hands is not used to like the the wide kind of like turning and stuff like that. Also probably to from typing and working all day. In addition, to that, by itself, injected it into my finger where it was hurting. Within 30 minutes, the pain was gone. I'm just like, man, that BPC and TB 500 and GHK are good. But Cardilax, for me, at least, has always been so much more powerful. And so you put that together with the BPC and the TB 500, the GHK and then KPV.

48:18 And then also PEG, MGF too, works really well. Much less known, those two cartilages, but I would add those, especially in the case of a shoulder replacement. I think one thing too Tessamerelin is great. Any Tesamerelin, Ipameralin CJC growth hormone, Those are always good, Especially in a surgery environment, just to help increase growth hormones after surgery is really good. Do I do one-on-one phone calls? I Do, but you got to find out how to get there. I just don't publicly advertise them.

48:49 So people know where to fine me and I don' do that because I dont want to be overwhelmed and it kind of eats into some other stuff. But for people, if they're a good fit, I will do a one on one phone call. How do you inject clove into the neck for bulging disc? I mean, I think the easiest way is just to get like right in the trap right there. Cause it's close enough to it. And a trap is pretty easy to inject into with an insulin needle. I don't know, Jen, what do think would be the best for that? There's someone you trust that can do it for you.

49:20 Yeah, I had pulled a muscle on my neck the other day doing something and I just had Taylor inject like into the trap. I like that because there's like usually a good amount of muscle there that's not too much in pain and it's close enough to the area, whereas I think sometimes like a bulging disc area. There's a lot of times like almost sticking out because it is pretty bony right there for a lots of people and so it can just hurt to inject right on top of that. Obviously the closer to the injury the better, but that's what I would do.

49:51 And then again, the cartilax and PGMGF too I think would be helpful in that case. It's a good question. Can you discuss if you see issues with staying on thymogen for a few months or even longer? It is helping so much with inflammation. I'm thinking about continuing for awhile. No, I don't think that there's any issue. Even if wanted to stay on it for year, The worst thing that would happen is that it just is not going to work anymore for that. But no, I don't see any issue with that at all because of the nature of really good benefit from it.

50:32 I would even say I'd probably feel better doing that than diamonds and alpha one for a year, even though I don't see really any issue with doing diamonds now for one, for that long. But I think the Imogen for as long as it's helping could be great. Yeah, I agree with that. I think it's probably cleaning up a lot of the residual inflammation that's there for someone. But thymogen seems to be, compared to thiamin, which is more of like a systemic inflammation reducer, thimogen, seems be more analogous to Thymus and Alpha-1,

51:07 that it is an acute inflammation reduction, immune resilience, peptide, both great to take. I can do Thimogon and Thiamalin together. Here we go. What are the benefits, risks, side effects of adding DHT-P or DHTE? So DHTP is dihydrotestosterone, testosterone propionate. DHTe is Dihydro testosterone enanthate for anyone listening to TRD for ester dial control, body recomb, sexual health, strength, fertility, cognition, and mental stamina.

51:38 I love it. And I'm not gonna do it right now for my fertility per se. There's actually evidence that DHTs increases in the short-term sperm motility and sperm volume. Although I don't want to play with that because I think in the long term it could be suppressive. So for the short term, for fertility purposes, I wouldn't say that. But for everything else, if estradiol running wild is an issue for a guy, so say you just had super high estrdiol, i would absolutely use DHT before I would use an aromatase inhibitor a thousand times out of a 1000. because it acts a little bit differently, but it will help bring down estradiol without

52:17 nuking it. And in the process, you're going to get better body composition, better sexual health. What you do have to be aware of is the ratio of the DHT to the testosterone that you are taking. DHT can be very suppressive of estradiol and relative to how much you aromatize from your testosterone, the DHC can extremely suppressing which in the long term will make your sexual health worse. Now what I prefer is the propionate version to the enanthate because that seems to be less oppressive of the estradiol.

52:51 So say you're using like a testosterone sipunate with a DHT propionate, the testosterone stipulate is going to help keep estridiol steady. And then the DHP proponate is gonna give you the pulse of DH T and then clear pretty fast to where it's not hanging around and acting almost as like a pseudo aromatase inhibitor to like where your estradiol can stay in a good range. So I love it. Cognition wise, it's great. Sexual health is great, strength. It's, great mental stamina. That's like probably one of those forbidden things that they don't want anyone to know about.

53:25 And I think relative to probably like Primo or Mastron, I would say you're not going to put it on as much mass as you would from Prima or mastron. But I like it. It's just one of those things. I wouldn't say difficult, but just not a lot of people know about it, it's not made a whole lot. That's kind of the anabolic rabbit hole I could go down. Probably applies to a small subset of They're listening to this.

53:57 What's the advantage to do SS31 and MoZI at the same time? Or is doing SS 31 first for how long and then Mozi better? Do you guys want to give your thoughts? I think doing, SS-31 first and running that for about six to eight weeks, seeing how you'll, and, then, moving into Mozzi and them running at for four to six or four, to 8 weeks even. Yeah, I agree, especially if you've never done SS 31. And, you know, starting with that, because kind of make sure your mitochondria is in good health,

54:30 the level set, and before you go on to the MOTC. I think I would agree with Taylor. Yeah. This seems to have been another debate topic that I guess people were saying that doing SS-31 first is wrong, that you would actually want to do Motsy first. is a wrong way to do it. Meaning that if you did MATC first and then SS31, or if he did them both at the same time, I don't think there's a way wrong to it, they're different things. The way I like to contextualize that, let's say someone's never did a mitochondrial peptide before.

55:04 Say they are in their 40s or 50s, that probably have a little bit of mitochondria dysfunction, right? Maybe they were like a bit heavier than they want to be, kind of tired, Will doing Matzi alone help them? Absolutely. I think no questions asked, Matzie will help. The question is, will it work better if that person would have done SS-31 first? I view SS 31 is almost like the cleanup crew because it's going to come in, repair the structure of the mitochondria, get rid of a lot of reactive oxygen species,

55:36 kind of act as an antioxidant. and set the foundation for the Masi to come in and do what it does even better. That being said, it doesn't matter if you did MAT-C first. MATC is going to improve insulin sensitivity, is gonna do what it does, act as an exercise mimetic. So is that person gonna, like is there gonna be a downside to doing MATc and then SS31? No, I think that's fine. I thing if we have a perfect world though, we would do it. Now the question of doing them both at the same time, i think you're just doing both of the time.

56:08 If you are remodeling, let's, ModC is the software remodel, SS31 is a hardware remodel. If we are remodeling our house, and we just come in and were doing both at the same time, you can do that, right? You can leave your house and then go ahead and remodel the foundation and also be like restructuring the interior and you know, doing stuff at same times. So I think you're gonna do both the time. I just personally prefer to go back and forth. Use SS-31.

56:39 SS 31 for me is a little bit more of like the rest and digest phase. So like I like SS31 when I'm kind of in a parasympathetic phase, and then Matzi, if I am like trying to lean out or trying like push things a little bit more, I think Matz does better for the context of that. But yeah, it's one of those ones, you know, either way is fine, however you want to do it. Kelly said, just to clarify, the amount of HGH was one IU. So actually, Kelly, that actually might be too low for you.

57:10 It might better to do two or three IUs, and that's why your IGF wasn't very high. She was saying she just pulled to the 10 tick mark, which in that case would have been one IU. Maybe go up. You could definitely go because a lot of times one is still below kind of a replacement dose for most people. I forget what the exact number is, but I think the average 25-year-old makes about two units of growth hormone a day, just naturally. And so one I use still just might not be enough to get the therapeutic effect. Jen, how much growth do you usually do?

57:43 I actually just do one IU. I have played with it though for two I use just but didn't really notice much of a difference in me. So I think it probably just depends on the person, but I'm at one. IU still and have I had great results with that. Yeah, everyone is a little bit different. Some people don't feel anything at all. I think a lot of that too. In my case, it has to do with pituitary function. And some people it's relative to how well their pitutary works and how much they're naturally producing that ends up being for them.

58:17 Brenda says, I don't see any issue with those. It kind of just is one of those things, take them when you can. probably the Matzi and the NAD are going to be better to take in the morning. But then the other ones is kind of up to you whenever you take it. Yeah. No, I don't see any issue with any of those. And you think about this like, because a lot of people are like I'm taking this, this this.

58:51 Is that good or is it bad? We don' know because it's kind like relative to your goals. I will say if you look at something like that, think of the pathway. So think of the pathways. Okay, we have KPV, inflammation, BPC, angiogenesis slash inflammation. TB 500, stem cell migration, GHK, a lot of different things, collagen production, stim cell, migration and DNA repair. NAD plus, raising NAAD plus levels in the NNAD cycle.

59:21 Glutathione, antioxidant, SS31. Mitochondria plus antioxidate, MOTC, mitochondria, thymosanophone immune system. When we say that, is there that much overlap between those things? I wouldn't say there's that. Much redundancy in there. There could be a lot more redundancies. And so when we, say like, Is there any issue? You got to find out for yourself, right? But I don't see that Much Redundancy and in those together. No, I would say if anything, maybe run the SS 31 and the MOTC in separate cycles.

59:57 But again, it does not hurt to be running them during the same cycle phase. Yeah. Kelly says, I agree about carbs. Used to be afraid of them, but have added in and feel better. Started to go under 110 pounds a week, not to mention I think it helped my T3, T4 conversion. Jen, you probably know the science behind this a lot better than I would, But that's the thing is I've just always seemed to see people have improved thyroid health from carbohydrate, even if it's just like supplementation with, You know, when I didn't do carbs, my, My favorite team.

1:00:32 So, Jen, I'd love to hear your thoughts on that. Now, you do see that in some people that do extremely low carb diets, not everybody, but I think there's such, it's a down regulation probably in the metabolism, which then your thyroid doesn't know what's going on if you're in a starvation mode. So you see some of the hormones and the thyroid hormones get affected to where they actually can go into a hypo thyroid level because the body it's always

1:01:02 trying to get homeostasis and it always try to figure out what the input is what we're putting in our body and its trying a regular to that so you do see that with some people and a lot of it to could be when you have those extra carbs your energy expenditure is up as well and so then your thyroid metabolism now finally starts ramping up So everybody's different but I do know people that have went to extremely low carb diets that their thyroid tanked. I'm not saying everybody but you do see that with people.

1:01:32 i did a very very low-carb diet and had some issues with my thyroid probably about five years ago. First it went very hyper and then it started to crash but as soon as I added carbs and changed my mindset around that everything just self-regulated. Yeah. Yeah, again, I think it was always as much as we can talk about crazy diets and stuff. It's always just going back to like a balanced diet. Protein, carbs, fats, eat the right amounts of each and you usually will do okay.

1:02:04 Especially if you're exercising and hormonally healthy. Kelly says thoughts on the pain after the after pain of glutathione injection. I just let it get in the way of my workout for days because it feels like a huge bruise. Jen, I'm curious, how much glutothione do you take when you use glutathiol? I mean, I vacillate back and forth on it. It really just depends on what my goals are. You know, i'll try to do it two days a week, maybe like about 100 milligrams.

1:02:34 it just it really depends. But usually it's on my when i'm trying to maybe just an 18 to 20 hour fast. I'll do that in the morning. i do know that there are some ones where you add the touring backwater that will help with that extreme pain that you're getting. from the injection. Also another way that you can inject it's called a z-track method that sometimes can help. So when you pull the the skin taut with your hand wherever you're injecting and you inject more kind of at an angle and then after you change the route

1:03:16 of how the fluid is going so it doesn't just get dispersed in one area, that could maybe help you with the pain that you're feeling at the site. And then I know you guys have talked in your lives before about massaging the area or if you have a TheraGun to use for this type of injection, not necessarily a peptide because those are more sensitive molecules, but that may help as well. But yeah, glutathione can be a tough one to take. Do you think if somebody has, if someone is leaner and doesn't have as much muscle mass, like if like, let's say a female who's like more lean or they

1:03:57 don't as muscle. Do think maybe doing a smaller injection amount would be better for somebody like that? Yeah, smaller or I mean, you could break it up into two injections with a smaller volume. So that's another option that you can do. I know it means another shot. Yeah. But it might make it not as painful and not have as big of a welt after you inject it. I will say I tried I've actually been using that that form of injecting of pulling and then releasing my hand what you just described and explained because

1:04:31 that's what he taught me and that has helped and made a difference. I didn't think that it'd make that big of a It can help to people that have I know on on the action group somebody was talking about sometimes they feel like the fluid comes back out through the muscle after they inject the Z track method will help prevent that too if you're injecting something and some of the food bounces back of a tissue or muscle. Yeah. Probably too, if you go on YouTube, there's probably nurse videos.

1:05:01 If you just do Z track method, it's like explanations of how to do it. Like they're showing them how do do in case people wonder. I think there are a couple of things. Obviously, to me, the biggest thing that has actually helped is not even the theragun. It's taking a little cross ball and putting it up against the wall. after I inject and then like rolling around into the wall because that seems to disperse a lot better than even that theragun which is kind of like on it. It's like whereas like the ball is like going back and forth so it like has room that it's kind massaging it out.

1:05:31 I think too for someone that struggles with it, let's say you're doing two injections of glutathione two times a week which are usually going to be one ml intramuscular. I think if you just broke it up into like 20 units every day, it probably is not going to have as much of the pain because the volume is a lot lower. Maybe you don't get to the same height as like a two ml per week, but let's just say you did five days of 20 It's a little bit more of like a shallow IM

1:06:02 injection because the volume's smaller. You still get good overall total exposure, and you probably get less of the pain and the buildup because of volume is less. And so that could be helpful too. I mean, people will do it sub-q, but the problem sub q is a lot of times you'll get a nodule where you're injecting at subq and it just sits there and then that hurts too So yeah, it's the unfortunate cost of doing business until someone comes out with a better mechanism to deliver glutathione, which hopefully will happen.

1:06:32 Yeah. I've seen, I'm seeing stuff that I think could happen, but I haven't tried one personally yet, there will be soon. It'd be cool if you just had like a glutothione sublingual or trochee or something you took every day and it had the same effect. Spanda says, what experience do you have with ATX04, including Antidote user reports, potentially more efficient than MotC? You know, they're a little bit different. Obviously, like both are going to be an AMPK activator. I don't think, I think Mot-C seems to stronger from a performance benefit, but maybe AT-X.

1:07:10 a better version of Metformin. And the issue is I've really just seen the benefits when I go to like five or 600 milligrams. Even in human clinical trials, the dose was a thousand milligrams a day and most people were getting 100 milligram capsules. And so they're like, Oh, I took it. I didn't feel anything. It's usually like I've had to go to five to 700 milligram range to feel like the performance effects, to see more of like leaning out. Cause it will lean you out and kind of harden you.

1:07:40 But it also, that can be cost prohibitive because If you think about it, one bottle with 30, 100 milligram capsules, and you're doing 500 milligrams a day, that bottle is going to last you six days. And so that's like two or 300 bucks for a week supply. You know, it's, like, is it worth that? I don't think it is worth it. Like if you were going put it up against Matzi versus the benefits, I do not think that is worthy for the, pound for pound. But I think I would be good to use. I will just say one thing I have noticed is, don' t take it around strength training.

1:08:10 I think, and I don't know specifically, I there seems to be some mTOR inhibition, which can be good for longevity purposes, but for the purpose of growing muscle, maintaining muscle. You don' want to take that pre or post workout because it can inhibitory to the muscle growth that would come out of that. And I noticed, when I've taken it around strength training workouts, it seemed to me weaker when it take it. Kind of similar, like if you were to do metformin pre and post-workout, you probably are gonna feel a little bit weaker. Cause again, it's working more than like the APK activation, more of like, the fasting autophagy type mode of the body.

1:08:45 Um, and so that's, that what I would say, but I know you like ATX. I love ATx. It's probably one of my favorite, favorite molecules. Like it anytime I take it, like I just feel like such a bigger difference. My abs look more defined. Obviously I only use it on fasting cardio days, I love ATX and I have no plan on stopping to use it. Like I think it's better than Sloop.

1:09:16 I like it better not see. Just cause I just like how I feel and how look when I use. But Jen, I know you like ATx. Yeah. After you had advised me how to, you know, to dose it a little bit, I was definitely taking too low of a dose. So it definitely can be costly because you have to take a few of the pills, but like you, the fasted cardio definitely felt more intensity during the workout.

1:09:46 But I also like MOTC. I think the benefit of ATX is it's oral. It's an injection that you don't have take if that's the route you want to go. Whereas MotC, it is an injectable, But alternating those has been great. Yeah. Do you know much about hexerone? I know a little bit. I would probably, if you wanted to dose it, probably like 100 to 200 micrograms a night. It's just a, I forget if it's a GHRH or GHRP, but it a very powerful growth hormone pulsing peptide, But it seems to wear off in like a four week window,

1:10:20 like where you won't notice the results as much. But I think it is great. And I also think too, from what I've heard, it can help with cardiac function more so than some of the other growth hormones. peptides. So for people with AFib, like I've heard it helps with that. Probably for People that get like tachycardic on a GLP, it could be like good in the short term to help improve resting heart rate, maybe even HRV too. And so like, I would see it much more in that lens, instead of something that's like long term that I Would use to improve growth hormone.

1:10:51 Doesn't it cause more water retention? Yeah, so I mean, the strong it's stronger, stronger system have more attention. I'm 56 years young, look 36 on TRT, CJC, no DAC, IPA blend, Mozi, BPC, Reddit TrueTime, best DAC I've done in a row, all best shape. There you go. That's all you need. Especially for people that don't realize like they'll do all that minus the TRG and they don' realize how important the testosterone would be.

1:11:21 Yep. Would Cardilax be good for a strain pulled lower back and abdomen? Absolutely. I would get on it ASAP. Couldn't find any info from Hunter on GHRP2, GHRP6 on peptide cheat sheeting videos. No, I just haven't really talked about those. Those are, it's kind of one of those things. It's like, why would you use those when we have Tessa and IPA? Those were going to be the GH RPS. Obviously GH RP is in the name. I think it was so much better. The problem with those is one, they will cause your appetite to go up a lot.

1:11:52 If someone needs to eat, meaning if they need an appetite, I would actually use those because they can increase appetite. Also, MK 677 does the same thing. So if someone wanted to increase their appetite you would, actually, use them. Obviously, most people don't want to use their appetites. That's why GLPs are so popular. But yeah, you can use it. It's just one of those things. You have to be careful with those, the prolactin and cortisol. Same thing with MK677. That's what makes ipamerelin so unique is that it does what it without raising prolactin and cortisol or really affecting appetite.

1:12:23 And that's with GHRP 2 and 6 would do. So I'm not like, it's kind of one of those things. It's like we have so much better stuff. There's a use case if someone needs to increase their appetite, but other than that, I don't really see using them. Let's see, should have been a little bit more detailed. Question was on pre-surgery and trying to delay surgery as long as possible. Yeah, kind of what I said to that question earlier of like adding in the Carlax and the PEG-MGF. So that should help.

1:12:53 Maybe even some cases help, maybe help you not have to have surgery. Definitely. Let's see. There are many protocols for epitalon, like 10 milligrams to 50 milligrams for 10 to 20 days, two to three times a year, and 100 micrograms to one milligram 10 days. 10 days for 10, or I don't know, 10 for ten days, I guess. I've been using 700 micrograms for10 days monthly. Is it harmful to use monthly? I personally wouldn't do that.I would do it maybe twice a year.

1:13:23 700mg is totally fine. If you're doing like one to two milligrams a day, I would maybe do that 30 days tops and do it once or twice per year. I don't think there's a benefit to taking that monthly. Now, is there going to be a downside to that? I just don' see the need to take it monthly, what do you guys think? Jen, I know you use, yeah. Yeah, just doing it a couple times a year is sufficient.

1:13:54 And you can do it for a 30 day if you wanted to, a thirty day dose. Twice a years is enough I feel. When you do a three days, is it 30 days straight or do you like five days on? I did five day on and then took the weekends off when I've done the course. Then I'll do another course probably in the fall. I think people, I mean I have heard people that are like, oh man, my sleep is so much better when I do that. I that's one of those ones you do not go into taking a patella and thinking that there's going to be some magical revolution in your health.

1:14:29 Like that, there is going be like oh my goodness, this is like completely revolutionized my health, over time it's like one those in the background that does a lot of good things that it's good to use. And we see that in the data from Russia, where it has been used. But it is just one of those ones, I think people, they are thinking this is going to be like, a lot of people have this fantasy about this magical longevity stack that is out there that you are just going take and it will reverse age you 25 years.

1:15:01 And there's some bioregulator protocol that's going to do that. Now, the bi-regulator protocols are great, but what I want people to understand, I'm not saying this person is asking this, because you hear about this. People think there is this magical longevity protocol, that is going reverse age them 20 years and 12 months. It doesn't really work like that, and honestly, if you want the most longevity protocols, it's hormone optimization. That is the fountain of youth as we have it today. And if you optimize your hormones, that's going to solve probably like 78% of the issues that people would have, you know,

1:15:36 and kind of help them. in the long run. And then sure, it's great to do epitalon and pinealon, thymalin, and some of these other bioregulator things for longevity. But I just want people's expectations because it is kind of one of those things. I think two people probably get into this and they are like, oh wow, this made me feel so much better. So there must be something more that is going to make me that much feel better and a lot of times epitalon is not going be the one to say that. Not saying it was bad, obviously. All right, let's see.

1:16:06 Simple stack protocol for SS 31 mod C5 amino sloop band 15 don't want to overspend order how long each that is a very long question to which it would require a 30 minute presentation. Sean, I would say probably I not use all those ones at one time. Obviously, I would say just with the overspend, the most you're going to have to worry about that is from the SLU. I don't think that's as big of an issue with any of those other ones.

1:16:37 Probably you could get to that point with Mozi, but I think it would have Ban 15 is on couplers. That's completely different. You're not really going to, that's going like be like the opposite of overspend. And so that just a really long question. I can't like sit without sitting down for 30 minutes and doing. But I think those are all good. It's just, you would want to use them at different, different times of the year for different purposes. With the exception being five amino, You can use that pretty regularly. Cause that obviously not I mean, it's indirectly helping mitochondria, but it obviously through the NAD pathway.

1:17:13 But yeah, that's just, like a super long thing that would take an hour long presentation on. The one I think that most people would not necessarily need is the BAM-15. That's one of those ones I think that would come into conversation with like, if you have a person that's like trying to get down to like really, really low body fat and they've done everything else and I can't do it anymore. And so I see less of a use case for that for general population speaking, like meaning that I don't think someone have to go to the uncoupling pathway

1:17:45 to necessarily get the results they want out of life. Oh, Best TB 500 BPC dose. I'd say 500 micrograms twice a day if you have a muscle strain. There you go. Is there a recommended way to stack sloop and MOTC? For example, using sloop during the week and on the weekends. Does that make sense from a protocol standpoint? I mean, I think it's fine. If I were going to do that, probably do SS 31 on weekends if I was taking s loop during week.

1:18:17 I would kind of think of like using sloop as like in an eight to 12 week window and then going to Motsey or maybe even taking a break for four to eight weeks and going back to motsey. What do you think? I agree. I think, I, think also too, if it's like the first time using slip, you should run a cycle of SS 31 prior to using slew. Cause again, your setting the foundation for the mitochondria. And if that mitochondr is already like, not functioning well, and let's say since it's like kind of messy, then you're going to add sloop and that's going

1:18:52 cause it to spin. So you are just going, you will be basically spinning messy mitochondria rather than if you use a sloop, it will go in and repair. Then you can go and use SS31. It will repair the mitochondrion. That way when you go to use your s loop, is going in spinning good healthy mitochondry. Yeah. Yeah, because when you finish and with it, sorry, when I was going to say when we finished that protocol, then go back to SS 31 for any of the redox that happened.

1:19:23 That's a good point. I think SLU can a lot of times amplify a bad mitochondrial state. You don't wanna soup up a 1988 Toyota Camry. You probably wanna get a new car first and then do some tune-ups to it. If I've never used bi-regulators, which ones would you recommend someone to start with or any bi regulators for energy? I can't really say because bi regulars have, there's so many different use cases. I don' know your individual health and needs.

1:19:55 And so there is not anything I would say is, Uh, like, oh, you've got to do this bi-regular first. Yeah, sure. There's bi regulars for energy. You could take, if you're talking about the oral ones, You can do, uh, endolutin. you could do a, Thyreogen, which is a thyroid one. Thyroid one's typically going to help with energy, so that's just hard to say. It's more, use case. I have bi regular cheat sheet and stuff people can check out and everything. So.

1:20:25 Johnny, I'm not sure what you mean. How deep would you want to take cerebral isin? I don't know if you'd mean like with what size needle or syringe. I mean, typically you would do it intramuscular because it's a five ml shot or a two ml. Shot or something along those lines, but I dunno how deep, how, deep or like how frequent. Not sure if. Drop that in. What about back saline for glutathione reconstitution? No, no, never done that. Have you ever heard of that, Jen?

1:20:56 No, just the, the touring backwater I've heard of that can make it a smoother delivery and less painful. Yeah. Are there any peptides in the pipeline that you're excited about or keeping an eye on in a pipeline? I mean, let me think in that pipeline. Hmm. Not so much in the pipeline as much as kind of like talked about this last time. It's just more stuff that people don't know about, like helping them understand it so they can use it.

1:21:26 I think VIP, I've been talking a lot about VIP lately. VIP is so good and no one knows about it, you know. Cardilax is good, no-one knows it for healing. Fat loss wise, I mean, obviously we have the GLPs. I'm thinking, is there any other fat loss ones? I think there's just a lot of ones that if you go onto any peptide website and look at that 80% of people don't even know what they're for,

1:21:59 how to use them or anything, and they could potentially harness the benefits of them. Like I said, Cardilax, Thymogen, Vessagen for endothelial health helps a lot. Velon, you know, Velan is such an amazing peptide and no one knows about it at all. Like no-one knows anything about Velin, how to use it, like what to do.

1:22:29 I take one milligram or two milligrams. You can literally inject Velant into an injury to help. It's going to inject itself too and it's gonna help with your immune system. What's cool about some of these bioregulators too, is everyone's like, there's this way to get views on social media and you can just go around and say that BPC causes cancer. And you just say that BPC has no evidence that it's going to help you and that causes cancer. So if you want to get views on social media and you're up and coming to social medial, just go say, that and they'll start new views. And, you know, what's interesting is like some of these injectable bioregulators. I'm not saying BTC is bad.

1:23:01 However, you could use VLON for the exact intent and purpose practically speaking as BPC and never have to worry about any of the downsides. And I think that's where it's like, these aren't in the pipeline. They're already out there, but no one knows how to use them. You could inject VlON, like I said, into an injury. you can inject it sub Q and it is going to reduce inflammation and all these things. It's just, no, one really knows about them, so that is what I would love to see is not necessarily a pipeline, just like understanding what we have even

1:23:31 more to do that's out there to like where you really, you know, people are like, oh man, I've got to cycle off BPC, but I love the benefits that I got for inflammation from it. It's like well, there's five other peptides out that we could do. That's going to the same thing, But you don't even have to worry about, ever having to quote unquote cycle-off if that makes sense. Do you have any favorite peptide that no one knows about?

1:24:04 No, I don't think so. I mean, probably my favorite small molecule is obviously is ATX. And I just feel like that's not a very popular one that people talk about. Yeah. Jen, do you have any favorites that no one knows about? Or talks about... No. No? I feel you though, though I do love the bioregulators. Because the science and the research has been around for years. and proven results. And then for people that maybe have trepidation around injections, then they can do the oral bioregulators and they're, they,

1:24:39 can be life-changing and you can cycle through them. You can take your 30 day supply and then later in the year, take a quick 10 day, supply dose for a refresh. So I think the bi oregulator is definitely are exciting to me, but in terms of like a, a peptide no one knows about. I don't think there's not anything that I mean, they all know about them. Yeah, I think I'm gonna change my answer. Sure. yeah, unless they go with P 21. P 20. One another one.

1:25:10 No, like people know, about it, but they don t know. About it. It's just not talked about a lot. So yeah. P21, I think this is like the best way to think about it. It's like cerebral lyosin light. Mm-hmm. Its diet cerebral lysis, like diet coke. P 21 is great. PE 22, 28 is for cognition and function. What I like about those is they're not like nootropics in the sense that you're going to be like, you know, it's not the limitless pill,

1:25:41 but they just seem to help so much with neuroinflammation. You know, Taylor and I talk about this and, I promise we're going to get to questions, but this has kind of got me down a rabbit hole. We don't use that many nootropic peptides really, if at all. And I feel like my brain function, we were all inside of our own head, right? But I think my function is pretty good. I like how I work. My brain is in a very good place.

1:26:11 I think a lot of people have severe, like what I am always like trying to put myself in other people's shoes. So many people will have a severe brain fog or they feel like their brain is just not working right. And they want to throw the kitchen sink of nootropics and sort of like, I'm going to take cerebraliacin, and I take this, take, this and take. This. A lot times one, it's hormones. Getting your hormones optimized is going make the biggest difference for your brain. But then it's also to like getting rid of inflammation. So like, what do you have from an inflammation standpoint that is causing your brain fog?

1:26:42 And then also too, I think people don't do a lifestyle practice of like categorizing their thoughts and organizing how they think about things. And so they just live in chaos. and so their brain actually structurally has inflammation because there is environmental stress on the brain from a input standpoint. And so it causes brain fog and everything because there's no like yin and yang inside the brain. So there is just like all go and then no slow. But to the point, I think a lot of people, they want to buy all of these nootropic peptides and they don't realize like,

1:27:17 of course, cerebral isin is great. Of course. P 21 is a great, of c max, it's a link and all the things out there are great but I think a lot of people just really, what I have learned is that a lotta people like really struggle for whatever reason with like focus or clarity or brain fog. And I don't think that the nootropic peptides are always the solution. I Think it could also be a lifestyle change. Idon't know. If you take, just to use an example like me and Hunter and Jen, cause I know Jen's lifestyle and routine is that the things that we all,

1:27:51 the three of us have in common, and I know neither, none of really overly, we don't really use neutrophil peptides that much. Right, Jen? Like you don' really using them a ton. And, but what's the, what are the thing that all of use have come in? We all read, We al read books to help us. We read fiction and we read nonfiction to hel with mindset and self-health. we all exercise and have a good exercise routine. We all prioritize our sleep.

1:28:22 I would say like probably out of three of us, I probably have like the lowest sleep scores. But I think also another big thing is, is that, and I don't wanna go down the rabbit hole, this is lifestyle, none of a strength. And I'm not hating on anybody that drinks alcohol, but I there is still a large, population and portion of people that are in the biohacking space that will still casually use alcohol.

1:28:54 And I think that makes an effect on, on the brain function, even if it is just like a glass of wine at dinner, or if you're at a work conference and you have a cocktail or two, it's just, that's something that I've just noticed. Um, and just still just how common it was for alcohol use. Not to say that with love. I'm not I am not criticizing anybody who uses alcohol. So Jen, I never thought this today conversation would turn into this.

1:29:26 But it's actually like I think it is a very prevalent thing because Taylor and I were talking about this last night. And so I Am not here to tell anyone how to live religiously or spiritually or anything like that. However, we have friends that are Mormon. I'm not a Mormon, I have Friends that Are Mormon I know like every religion has its problems or different things. However Mormons on the whole don't drink. That's like a big part of their religion is they don' drink and what I would Taylor and I were talking about is we were like,

1:29:56 why are Mormonts typically like Mormonds are very entrepreneurial. And I love, I loved that aspect of like, just being entrepreneurial or entrepreneurs. I'd love to study successful entrepreneurs and anytime you see patterns in groups of people, you're like you ask yourself, like why is that, why does that pattern there? Especially if it's a good thing that you would aspire to do. And Taylor and I were talking about like, why are a lot of Mormons so good at business? Like what in their culture? I'm asking that the same way that I would ask, like why aren't Germans good of making cars, right?

1:30:28 like I was in my house thinking like Why are Mormon's so go to business as you know, the way you would say, you why Germans go cars? Why our, uh, You know like like wire tacos from Mexico better because it's like part of their cultural, Right? You now, so but we were saying like we're Mormones go business. And I was like, maybe because they don't drink. And if you have the cumulative effect of years and years of never getting pulled back down with the inflammation in your brain, you start to get like really good at progress in the abstract nature of working in business and working with your and having mental clarity and stuff.

1:31:07 So I'm sure there's way more behind that. I would venture to guess though, if you looked at people that don't drink versus people who do drink, even if they just drink casually, when you compound that over time, think about like the compounding effect of not drinking on your mental clarity. how far that will take you versus like always getting pulled back down, even if it's just like two or three drinks, you know, a week of like what that's doing. I think two from like a, like for me, it was more of a clarity thing of how clean can my thoughts be?

1:31:42 Like how focused can I be and I don't know. Maybe there's something to that. I will say like, do you like? I mean, also, like I think Hunter and I have very different backgrounds. I used to be somebody who used. To drink on a regular basis. Like there was probably like maybe like three days out of the week, I didn't consume alcohol in a sense, whether if it was like one drink at night or whether it. Was like four drinks out with friends. And I feel like for somebody. Who used a drink, notice a huge difference in my brain function and brain clarity.

1:32:17 Um, I know Jen, you were like the, kind of, kinda the same as me with that too. Yeah, I was, everyone in my family though, we would get sick very easily from any type of alcohol. So even after like one glass of wine, like the vomitus muchicus would happen. That was definitely a deterrent for me. I just knew that I had kind of an adverse reaction no matter how small the amount.

1:32:47 But even if it was just a glass felt like I had drank an entire bottle, just a pounding headache, terrible performance at the gym also would really make me impact my blood sugar levels. Like I would definitely feel like they were more labile, kind of up and down for me. And even if you just look at what it does in terms of the inability to burn fat as effectively and to, you know, lift and perform in general.

1:33:21 I feel like anytime there was alcohol involved and again to your point not knocking people but if ever there is a party or get together it just seems like you know you would know when the drama was going to start you now late into the night depending on how much of the drink so I think it's just made my life a lot more. peaceful when I stopped doing it probably about four years ago, and I haven't felt like I miss it. I think it makes people uncomfortable when, when i go out with them, but I'm not judging. We don't even have a conversation. They ask more about it than, than I would ever try to probe with that because it's a personal choice.

1:33:56 i think It just sometimes makes People uncomfortable if we're all out and, you know, we are not, We're not having an alcoholic beverage, But it is no judgment. Yeah, yeah. I think if anything, I feel like we get more judged for not drinking. Are you being a victim right now? I'm being victim. How dare you? Just kidding. Yeah. It's just one of those things when I, always doing my best job to put myself in other people's shoes, like understand how they see the world.

1:34:29 And I see so much around the nootropic side of things. And to me, that's a signal that a lot of people don't feel like their brain is functioning optimally. To me I'm always like, okay, well, what's the solution to that? I think what Taylor said, too, is the sleep thing. I always forget, unfortunately, I am in a place in my life where I usually get to sleep seven. or seven and a half hours a night. And so I make that a priority, you know, and we all have our lives and different things that will affect our sleep and stuff. But I am always like surprised at how many people only usually sleep like five hours at night and your brain will suffer.

1:35:05 If you have long periods of time or you're just sleeping six or less hours of night, I think even the difference between six and seven for brain health is crazy. Like you take someone's brain. I'll tell you this. If you gave me six hours of sleep a night, and most people only get six hour sleep at night. If he gave you six, hours to sleep in night for a month, I would be a different person. I will be grumpy. It'd be Grouchy. Yeah. Be relying on stimulants. Like I'd, be on caffeine too much. No, not be good.

1:35:36 And when we're at conferences and we can't get like the, like when you don't have your full sleep amounts, you were, your not fun to deal with. Like it does affect you. Of course it is. Yeah. I'm just saying that even the, like seven hours for me, I'll be good on seven. Hours. But the moment it becomes under six hours is bad news for. For whatever reason that like one hour will make such a big difference for, and I think the long-term You know what, like if I did six hours of sleep for

1:36:12 a month, I would probably be fiending for nootropics. Cause I know my brain would not function in the same way. I think also too, there's probably something to like the abstract nature of dreams and everything that like helps organize my thoughts in a way to where I have a much clearer view of the world. through my eyes when I sleep enough versus when. I don't, when, I can even still be like pretty healthy, but I'm not thinking from a higher plane of how to help the world.

1:36:46 Yeah. I want to share something that you just reminded me. It was probably 15 or 16 years ago and I was in the ER and used to work. probably even longer than that. I would work three in the afternoon till three on the morning. So talk about messing your sleep cycle. And obviously we always have a lot of law enforcement officers because they like to bring us different crisis in middle of the night.

1:37:17 One of police officers, it was probably two in morning and my kids at the time were very little. Obviously not getting a sleep once I got home. He had me simulate in ER a field sobriety test. Walking a straight line, and I was walking like I wasn't paired. And so think about that people that are doing shift work or people, that or sleep deprived and then they have jobs where they're operating machinery. They're treating.

1:37:47 patients and then it has the same implications on your body as if you are impaired taking a drug or, you know, some type of chemical that can alter you. So think about people that are constantly in that state. Obviously you're going to do poor decision-making. You're gonna lash out at people. The importance of sleep is we just can't preach about it enough. That's crazy. And that brings me back. Just hearing that story and I know we have a handful of first responders that listen to us.

1:38:20 It's like, I don't think legally I'd ever be able to do this, but eventually someday I would love to be to have like a peptide charity donation for first responder workers, because it's crazy just how much that can change. How fast will we get canceled if I started at Cherry to give away peptides to first responders? Is the question. Well, I guess I've been canceled off of everything except for X so far. Yeah, we need to do, think about the cortisol levels.

1:38:50 I mean, all of that, definitely something for us to think. Because yeah, it's always been on my mind too, because, you know, just for some of the first-responders that I have been able to meet at these conferences, there's just some the sweetest most kindhearted people and it's like, it jobs like that, that I think are underserved. And I don't think they're underserve and I dont think that they get the appreciation that the deserve and that's always been something that i've always

1:39:21 wanted to give back to. So thankless profession, that's for sure. Thankless Profession. And if there's any group that would benefit from peptides the most, it would probably be them. Especially just even with the circadian rhythm thing, which is kind of interesting because circadian rhythm peptide, you've got VIP, DCIP. orexin, some of these other ones that are actually helping the hippocampus and the hypothalamus with regulation of circadian rhythm.

1:39:51 It's pretty cool. VIP does that. So VIP will help reset your circadian rhythm to kind of get you back on track from a brain standpoint. But long rabbit hole. Yeah. Sorry, guys. We will continue. Back to your questions. Kelly says, what are your thoughts on the Metformin study that came out saying it reduces the benefit of exercise and strength training? I do think that is a real thing. The question is like how much and also to I would say to people that are, I think it affects people on hormones differently than it effects people are not. And so probably for people who have low hormones to begin with, that they're not optimized, probably going to have more of an outsized effect.

1:40:25 than someone who has higher testosterone levels. The question is, is there a dose of metformin that is still good for longevity relative to that? I would say 500 milligrams a day is still beneficial. Yeah. Until I see otherwise. But, um, you know, a lot of people I've kind of, I don't want to say I'm giving up. I just kind given up though on trying to convince people that metformin is good. It's kind one of those things. You just get beat into submission. If you're in, if you are a proponent of met formin, people just beat you and beat, beat and beats you into a submission,

1:40:58 it's bad. And, you know, to be honest, it's like, we have Giardians now and it is like one just kind of want to use, if I could only use one, I would use Giardiants. I still, take 500 milligrams in that form in a day. But I just think like it just, kind like you, know the American history in the South, there was, called the lost cause. And so after the Union won the Civil War, In the South, there was this sense of just despair and desperation.

1:41:29 I'm not saying it was right. Like, I am not supporting the Confederacy, obviously. But it's just interesting in American history, you have this, like, notion of the lost cause in the south and this like 20 to 30 years of fallout after the Civil War of like their entire way of life was just kind of, in shambles and they had to restructure and everything. And I kind of think of like the Metformin battle is just like, the Peter Atiyahs of the world, God love them, is like they're just going to beat you into

1:42:02 submission with the metformins is bad, because it's a free drug that's like does a lot of good things for your health. But we do not want the population on that. We do NOT want people getting met formin. and we're just gonna beat it into submission. And so, you know what, maybe I just throw in the towel on the Metformin argument. You know? And as someone who has used MetFormin for years, like I have, it has not impacted my ability to build muscle. I've built muscle while taking a thousand milligrams of MetFormin a day. My 22 year old daughter's on it. When she was at FSU in her metabolism class, her professor actually told the entire group of 20 year olds at the time that,

1:42:39 they all should be on Metformin. And she's got, she has an incredible physique and little abs and she a little Pilates person. I mean, it's not inhibited her muscular development by any means. Yeah, I'm still a proponent of Metformin, obviously. But in terms of the, the whole debate slash, whatever we would call it, controversy or whatever, you know, it's crazy, there's still studies coming out this year. I wrote an email, well, last year, wrote email a few months ago, because I was just like going through some of there's still studies and studies that come

1:43:15 out in the show, like there are benefits to taking it. And it's like you can take one little piece of like something that it does, the strength and exercise, and then just throw the baby out with the bath water, so to speak. But I think where we're at with Metformin in the debate sphere, it's kind of like the post-Civil War South. It's the lost cause. A lot of people are just not going to be convinced anymore. I do think, however, in a case of a woman with PCOS, works amazing.

1:43:45 Yeah, absolutely. In cases with people that struggle with gut issues like ulcerative colitis, Crohn's, those things, Metforming can be a lifesaver. I'm just tired of having to defend it. And it's just like, why anymore? So Taylor, how many milligrams of ATX do you take daily? Anywhere between like minimum 200 milligrams and I've taken all the way as up to 600 milligrams.

1:44:15 So anywhere between there is good. Yeah. Are there any peptides or supplements you recommend for addictive behaviors aside from GLP-1? Tough question. That is a tough question, I could almost say like maybe. I, this is just a thought theory is that. If you are somebody who has addictive behavior because of anxiety driven behavior patterns with anxiety, something like P 21 would be beneficial to help

1:44:55 with the anxiety. Therefore it would help. With the addiction behavior or even. That's just me. Yeah. I think like, well, I. Think of like addictive behaviors and Jen, you'd be good. Well, let me just say, and then I'll ask her. It's like I, think of addictive behavior is in a lot of cases are driven by a lot of things, but I think dopamine seeking is one of the main, if we looked at it from a neurochemical perspective, it would be like the dopamine drive is what is craving the addictive behavior.

1:45:31 That's why GLP-1 works so well because it modulates dopamine and like, the mesolimbic system. So I, think like P21 is good because there's like modulating neurotransmitters. Maybe some of these peptides that are like neurotransmitters are going to help because it's going help with that. I think tesofencing actually probably would help a little bit with like addictive behavior in a way, not so much as a GLP-1. But I don't know, Jen, what do you think? Because that's at the intersection, the crossroads of your research.

1:46:01 Yeah, I was kind of thinking about what you just said about teso-fencing just because of that, you know the impact that it is having there on the serotonin. But also you know i'm wondering again it's anecdotal it just from the women that i've worked with. That can you need to be here can be also that you're just a very reactive person. Maybe like a quick trigger and a lot of the women that I've worked with that are on LDN now, low dose naltrexone, it is amazing of what a stabilizer,

1:46:35 and I don't mean stabilizers like they were off the cuff, but just tended to be more in their heads and more reactive. And then again, what it does with the inflammation, which if you have inflammation in your brain, you know what that's going to do with your behavior. I have seen just unbelievable results, even if they're just at three milligrams or four and a half milligrams of LDN, how it has really changed their behaviors. And of course, obviously, hormone optimization has helped them as well. Again, that is anecdotal and just observational on my part of the different people that I've worked with.

1:47:10 So that could be a possibility as well. You know, now you say it too. I think oxytocin would be another one too, like if you, let's say you went into a casino, which I hate being in casinos, but like some people go into casenos and it's like the lights turn on for them. It does the same thing around foods. If you take oxytocin before a meal, you'll eat, but you're just like, eh, I'm not excited about eating because I feel good. Same thing with tesofencing too. It's working similarly, albeit in a different way.

1:47:41 But I think that could be another one too that, oxytoxin would be more of a short-term thing of like hey, your about to be in an environment where you might want to drink, take some oxymotoxin, it probably is going to reduce the craving for the drink. LDN, that's huge. I didn't think about that. That would also be huge for a lot of people. I think with oxytocin, there's some studies that I had come across about people that have social anxiety disorder. When they do a low dose on the oxy tosin, it helps them to feel like they can get out of the house and be around people more often.

1:48:13 Like, if they had like an agoraphobia or some type of just social, anxiety disorders, well, that could help with that behavior. Yeah. Would you recommend doing FOX04 once per year as a general longevity research protocol? Yeah, sure. Just do like one milligram a day for 10 days. That'll get you through one bottle. And I think that's good. I thinks that enough for most people if you don't have something that is severely wrong from an inflammation standpoint. Can you take hair loss treatment, the mix of deutasteride, minoxidil and still use testosterone sip?

1:48:44 I would say like, if you're going to do those, please be on testosterone because there's are gonna, deuterosteride at least is going inhibit DHT. And so like your best bet of having a calendar to that will be the testosterone. I don't endorse the use of those. whereas the Dutasteride is more of a DHT inhibitor. So you're not going to feel good. At least a lot of people don't. Finasteridide obviously would be the worst one. But before I would get on a route, I'd try AHKCU, not GHK, but AH KCU works more on hair.

1:49:21 And so that's going be more like in topical hair products. GH K is obviously great. Hey, if you are worried about it, try the peptides. You have nothing to lose. And then, you know, if you, If you are that worried about it, like just go to those, but yeah, I would say like testosterone would be almost like a requirement to me if I was going to go down that route, which I don't plan on doing. Yeah. I protocol besides be so Luton. The doing eye drops with the BPC to be 500 blend or just VPC.

1:49:52 Eyedrops I have a video and basically just reconstituting that with saline solution and or contact solution. And using those and then I also notice a difference with my vision when I use P 21. It does seem a little sharper. I would say also. Um, it's Molina 10 one can also make, um, I feel like that makes things more vivid when use Molana 10. One. So I will say that, but definitely the eye drops with the, with a BBC. Yeah.

1:50:22 You can also make KPV eye drops. Those aren't going to help with vision as much, but they do help like eye injuries. And then SS-31 will help too. Even just injecting SS 31 will also help, you can make SS31 eye drop. In the BBC eye-drops I've had a lot of, because I haven't dealt with floaters, I have helped several people reach out to me and say that it's helped with their floater. Any thoughts on Oprah's recent appearance on The View promoting GLP-1s claiming the obesity gene drives overeating?

1:50:53 You don't overeat and become obese. Obesity causes you to overeats. I mean, I do think there's some truth to that because if you have two obese parents that make an obese child, the DNA transcription of the child will be much more likely to be obese because of time of conception. The DNA of those child. Now, does that mean that lifestyle and environment don t play a hand? Of course not. But I do think you have people now that have a proclivity to be obese because of either having obese parents because Of the environment that they're in which gets turned like to signal genes that will encourage obesity And then you also have two that like the lifestyle now is just not encouraging to to

1:51:30 Be fit for people and so I Do think that there is like a chicken or an egg argument there that like obesity does cause you to overeat. So that's why I think another reason that GLP ones are miracle drugs is because of that. But I don't necessarily disagree with that statement. I It's easy to say if you've never been fat that like, Oh, that person just undisciplined or whatever. I don't think it really is so much of that. Like it's so easy. To just say fat people are like lazy slobs.

1:52:03 They can't control what they eat. In some cases that some people. Are like that, but then a lot of people aren't like I know a of the people that have been fad, they're like probably eat healthier than 80 to 90% of. And it just like they've either been father or wife, you know, and like Dave. and their hormones aren't right. And then also too, like obesity causes hormone suppression. So like what they found is that GLP-1s raise testosterone, not because it raises testosterone because they lose weight and then their testosterone goes up a little bit because now they're not as fat. I do think there is some truth to that.

1:52:33 Imagine that who would have thought in 2026 I would be agreeing with Oprah. She is a master of interviewing people, I will say. Yeah, she is. Oprah is up there. She's like on the Mount Rushmore of getting people to say stuff that they probably like to interview people in a way that is entertaining for people. And she has Oprah has golden retrievers. So Carlyle X works so well. Does it repair or also pain receptors?

1:53:04 I mean, there's a possibility for overtraining more again. I think Cardilax is really just suppressing inflammation at the site. So it's working through DNA signaling to suppress inflammation that's expressing through the DNA, which is why I thing it works so well. Johnny says, my thing with the nootropics is whether they are just to upregulate in the moment, whereas I want something to heal the brain. And I that that where like cerebraliacin is much more in that vein. Cerebralliacine, P21, are much in more that vain of just healing the brains. Don't take cerebelliacein and think that you're going to be cranking out an Anne Rand novel in a month. It's not going happen.

1:53:35 fun, fun side note, I'm going like down the rabbit hole this morning. You know, Anne Rand was a massive, uh, meth amphetamine user, meaning that like whatever they had as Adderall back then, it was actually just meth, like meth pills. Taylor's like, who is Ann Rand? Is that who wrote the interview at the vampire? Oh, yeah. I think it's Ann Rice. Anne Rand wrote Atlas Shrugged, The Fountainhead. She was a proponent of capitalism, she was Russian.

1:54:08 she has some pretty profound novels, philosophically speaking. Taylor's getting so annoyed. Jane, have you ever read Anne I've not said don't feel bad Taylor that that's okay. So she did she Did methamphetamine salts, but it was yeah back in the day Yeah, that was that would make sense and probably kept her focus for hours and hours in hours Books Imagine being a writer back then, it was probably I think she wrote in like the 40s and 50s.

1:54:42 She had come out of communist Russia and escaped and came to America and her novels are basically about the idea of like individuality and creation and capitalism and having the freedom to like, operate independently of the state trying to tell you how to do business. So there's a lot there. But imagining a rider back, then because, you know, like all the riders did, coffee and cigarettes, and then you get some whatever the meth. The meth was created to help pilots be able to like have like where they could fly for a long period of time without having to get asleep and just getting

1:55:14 your hands on whatever meth it was like not crystal meth but like methamphetamines the way that like pilots would take them and uh just like having that and like sitting in a typewriter just I just bang out like thousand word novels. Um, so anyway, didn't know I was going to talk about Anne Rand this morning either, but to the point, I think that's where I, think what a lot of people want is basically like to have that feeling and like cerebral isin is not going do that. What's up Leo? He said, Oh, a love for you to talking more about spirituality and ties into health.

1:55:47 Well, there's a lot more where that came from. Jen is definitely, Jen, then Jen as a guru at that. That is one of Jen's specialties. Well I would say inside of our group, we actually have a book club call before our health call every week. And it's not like, it is not religious or anything like that, It's just more of a mindset sharpening, iron sharping iron call. So if that's your, you know, if, that tickles your fancy, uh, We do have book-club call, every-week. Um, and it was really fun stuff if you want to come in. If not, this is totally cool. Like there is no, its just us hanging out.

1:56:18 Here you go, why would you drink? Why would drink when you could take phenibut? LOL. That's funny. Dose protocol for five amino mozi NAD 10, 10 10 100. So that's on the cheat sheet. Download the cheatsheet. That'll be on there. It's On there, so make sure you check that out. Hey, Debbie. She says her son is a firefighter. Always asking me about peptides. What would be a good starting site for him? I think for a fire fighter, you know, the probably deal with inflammation. I would always say like PPC TP 500 probably is really good place for the firefighters to start. Um, You know just help with some inflammation recovery.

1:56:52 Yeah, Rebecca husband is law enforcement has worked nice for many years started peptides this fall. My struggle is when to dose him seven AM is bedtime, half the time other half time is 10pm. I mean, I think it's fine. Really like the dosing timing is not as big of a deal. I think if anything, it's probably with the growth hormone peptides more that you would see that. And so like you'd want to dose those like either before bed to help with sleep. But otherwise, like most of the time, most peptide are like not, there's not a lot that would say like have to be timed very strategically or that that's mandatory.

1:57:30 Nine MEBC, C max length for addictive behavior question above. I mean, you potentially could nine MEB C is to help reset dopamine receptors. So you could potentially use that I've never personally used that, but you probably could do that. And I don't know that you'd have to go that far based on some of the things that we talk about, But you know, for someone that is struggling, they potentially. Yeah. Kelly says I have VIP haven't tried it yet. Cause I'm kind of nervous of the immediate effect. Is it always like a head rush or body flush?

1:58:00 I mean, it probably will be, I would start if you're scared to start at 25 micrograms and then you can kind build up to that and it will not be as strong as your body gets used to it. I feel like it was kind. The same like flushing for me, It was kinda the same flashing feeling I got the first time I took it, but Morell and NCJ Siebel in together. Yeah. Jen, did you have the same experience? Yeah. Yeah, it's in between that and oxytocin, but it is just like a flush of warmth, maybe.

1:58:32 It's not bad. My husband's having hair growth from red. That's another thing, too, for hair like red light. I do a red light medical grade redlight bed. And if you're in the triangle region of North Carolina, check out NC radiance, ncradients.com shameless plug for my mom's red Light bed studio, but red lights makes my hair grow like crazy. It also for me, it like makes me grow on my back and stuff, which is annoying, But it does increase hair growth.

1:59:08 Um, what happened to Alex? I think Alex took down on social media. Cause he said it was stupid. Yeah. So probably just to take it down also before it got deleted too. But yeah, social, yeah. Alex has a private group. I would recommend school in his group, like definitely recommend people going there. It's a really good group and obviously Alex knows a lot of stuff that I don't know for like advanced protocol stuff. Um so Alex is amazing. We probably should even do a show soon with them. If time permits, both of us are really busy, but love Alex. And, you know, I do think from what I saw inside his group, he took down the social media.

1:59:39 You know social, media is ruining the fabric of society, which leads me to my next point. Who is John Gault is the question. I'm just going to put up who is john Galt everywhere. So Taylor and Jenner are looking at me like, what are you talking about? For anyone that doesn't know in the fountainhead by, or excuse me, not the Fountainhead, in Atlas Shrugged by Ayn Rand, the main character is a guy named John Galt. And John galt is, he removes himself from society because he sees the communism taking over in society.

2:00:12 He is as a businessman and a creator and he actually goes underground and they actually like build basically like an off like off-grid city where all of the entrepreneurs go and then all the Entrepreneurs leave society and it completely goes to crap. And what happens is there's posters and signs and in the book that like everyone puts up and its who is John Galt. So who it is, John. It's kind of like a saying is like where did my social media go? Who is Jon Gault?

2:00:42 We disappeared because like they obviously like your YouTube and my ex is still up. But who is John Galt? It's kind of like, you know, like all of us are leaving because the mainstream has gotten so bad that all the creators are going to have to remove themselves. That's why Alex removed himself just because of, it's like you now they're going remove me. I might as well just go ahead and just remove myself. It's actually probably smart that he did that too, that way like before he starts getting flagged and then it's like loses. Yeah. Loses the content.

2:01:12 So like where did Alex's content go? The response to that would be like, who is John Galt? I see a t-shirt idea we should start wearing that says that. It is a good marketing idea. We've always kind of joked about like doing merch stuff because I was like who's going to buy our merch? Yeah, trucker hat. can work on that this afternoon. What would be our version of who is John Galt for like the peptide space?

2:01:43 Maybe it's like, it'd be like what is, what it is like a peptide. And then like it would be kind of like an inside joke. You always want to do like and inside, cause who is John Galtz kind like? An inside. Joke for, um, like very pretentious, uh, you know, capitalistic philosophical readers like myself, if you're into philosophical interview with a vampire and rice books. Well, you know, I think there's actually benefit to reading some Anne Rice books.

2:02:15 I've never read an Anne rice book, but the structure of fiction actually makes us navigate reality. There's a reason Freedom McFadden is so popular. Freedom came burst onto the scene and now has published crazy number of books, taking the world by storm. She does have some good books. I've read one or two. They're pretty good. Palette cleansers. Yeah, they're good if you just get stuck on a book. It's not right.

2:02:47 You can just make get through those really fast. There's usually always good, she's got like good twists. And she is good at the twist. It's always more fun to read a book. Cause like, if you get it like halfway through a buck and you see where it's going, you know, it. Yeah. Like you want to see like what's, what going to happen. I think it helps you with your imagination too. When you read fiction, because then you're visualizing what the characters look like. That's how we always get disappointed when the movie comes out. And you were like that's not how I had imagined them.

2:03:17 Think it helped you use that part of your brain. Yeah, with fiction too. I think this has actually like been studied. People that read fiction are more empathetic because you're able to put yourself in the shoes of someone else because your reading through the eyes of usually a first person or a third person narrator in a fiction book. What I just, it just makes me think of like some people that I know that like they don't read and how I can see that non-empathetic side play into personality sometimes.

2:03:52 Also understand too, some people just don't have empathy. Is there a peptide for that? Oxytocins? Yeah. Uh, Shina says, yeah, when they take away your Instagram, you'll lose all the messages. That's honestly like, I obviously I don't post like a ton of personal stuff on there, but that's probably like what I was most sad about is like all of the conversations that like I have to win with people.

2:04:22 Yeah. And now I'm just on Marco Polo sitting gym videos all day. Hunter, am I still having benefits from the injectable estrogen weekly? Help still on it, but get a little worried about his shrinking testes. No kids in the future, so no worry there. I'm not using it right now because I am taking HMG and HCG to help with fertility, which is going to aromatize more and so my estrogen is like perfectly high.

2:04:53 as an adjunct to it to help with testicular phonus estrogen is a great option because you get a little bit more of the aromatization necessarily or a bit of estradiol without like the thing with the injectable estrogen you can kind of control it whereas with HCG it's going to be kind like a random amount that aromatizes whereas the estrdiol injections you could kind have it like you can titrate to where is the sweet spot for you. But yeah, I think if like the shrinking testes feels like an issue, you could always add in 250 IUs of HCG a couple of times for a week.

2:05:27 And usually that's enough to help with that. I still think even in that case, there could be benefit from estradiol injections. i'm just not personally doing it right now because of the fertility stuff with us. With HCg plus HMG, You don't really need that much, especially doing the higher doses like I'm doing right Hey, Sarah. Hope you're doing good. Did my first VIP this morning, 50 micrograms, a little flushing, but nothing like a nice and flush. Yeah. I think, yeah, for most people, if they start with 50, micro grams, that's good 100. You're going to notice it more, start at 50. Do that for a few days

2:05:58 at least. And you'll probably notice that it doesn't even do it anymore. Then you can go up to a hundred and then you will be like more tolerant of the flushing. Yeah, read Atlas Shrug four times. So good book. And I think that's all the questions. Yeah. Good call today, everyone. Sorry about the technical difficulties getting started. That was on us. We had the tab open, the other thing, and that was why it was echoing. But thank you, Jen, for coming on. Also, I'm going to put your Substack link there.

2:06:30 Let's see. Copy. Paste. If this works. So I'm going to put Jen's sub stack and then there it is. So just substack.com slash at Jennifer Seeger and Seager is spelled S E G U R. But check that out. Substacks, especially when it comes to mindset.

2:07:00 Everything like I think one of the things that I struggle with the whole like mindset and self-help of books that I've read in the past is that no one knows how to give examples and the actions to take. And that is where like Jen does that better than anybody that, I have any book I'd ever read, any therapist I ever talked to, Jen is able to get those advice, that advice on that plan of action to have to actually apply those things to your life.

2:07:31 Yeah. So. Cool. Well, all right, everyone checked in out. And if you guys like this form of content, this is where like, basically, just like how it is in the axion collective in our private coaching group, a little bit more structured with our halls. But if he liked the interaction of the three of us, definitely go check out the Axion Collective. That's the best way to obviously work with the Three of Us. So yeah, thank you, guys, so much. Thank you Jen for joining us. this morning.

2:08:01 I know that I originally, have you read my email? It was supposed to be a different person and that got changed. And instead I got to bring my other favorite human in the world onto this chat this. Morning. So thank you, Jen, for joining us. Thank you for having me. Yeah, you're welcome. Thanks, everybody. Maybe we'll see if we're going to be back next week. We do have some stuff coming up, so we will see. You guys just be on the email list and we can announce it the day before. That's the best way to know. Thank you, guys.

2:08:31 Have a good weekend. See you.