Thymosin Alpha-1: 2025 Update on My Favorite Immune Peptide

0:09 Hey everybody, this is Hunter Williams. I hope you were doing amazing wherever you might be in the world today. Today I'm doing a bit more of a simple recap slash update video on Thymus and Alpha One. For a couple of reasons. One, it is October 30th of the filming of this video. So I'll probably be released next week in November. This is typically the time of year people start to get the runny noses, the colds, flus, what have you. And time is not for one is an absolute must, at least in my household to have on hand for those things.

0:43 Then also too, just because I think as we progress in the research world and most of you guys that follow me and listen to this stuff are on the fringes. I would say shame on you for being on I'm just kidding, but we're on the fringes and there's all these amazing things that come out and that we were talking about and then are kind of on cusp of discovering, which is awesome and it's so cool. But a lot of times we forget the basics and thymusinophil-1 is one of those basic five or 10 peptides that a newbie would be so excited to see in their life.

1:18 A lot in the research world have been using it and we have it, and know what it does. But I want to do a recap video because I think a lot of times when we get away from the basics, we fail to realize like how powerful some of these compounds really are. And when I went back through and just made a slide deck and some research on thymus and alpha one, I was like, man, you forget all the amazing things that it does. Some of the data even behind it has a peptide that we have. I wanted to a video to update that. So obviously we're heading into that time of year where this is on everyone's mind and you may or may hopefully not going down to the local Walgreens or

1:54 CVS and getting whatever they have there. You could maybe have them as an Alpha one on hand to provide you with some protection from whatever, you know, is floating around out there this time year, where everyone tends to get sick. That being said, as always, check out the link in the description. I should have the links down there to sign up for the peptide cheat sheet. That is a new version of peptides cheat that I made this September. It has a lot of updates on different blends and things that are out there. So check that out. And then also too, don't forget to make sure that you're on the email list again, That is the best way to stay connected with me.

2:32 Right now I'm publishing stuff on Spotify. That seems to be going totally fine so far, but if anything were to happen in the future, the place to follow me is on the email list so that if I do have to start a new social media platform, start new YouTube channels, starting new Instagrams, whatever it is, you're there. So you were connected to me because that is only the only channel I own. And I know it's annoying to have do that, But it helps make sure that you can stay in contact with Me. Should you want to actually Be doing so. All right, that's it. Let's hop into the slides and today we're gonna talk about thymus and alpha-1.

3:02 Alright, let's get into it, thymosin alpha 1. This is going to be a comprehensive guide to how thimus alpha one acts as an immune system modulator. Just to give you a little bit of background, TA1, which is what I usually call it is a 28 amino acid peptide hormone originally isolated from the thiamus gland, Which obviously shrinks as we age. and this naturally-occurring immune system modulator has emerged as a fascinating therapeutic agent with wide-ranging clinical applications, all the way from cancer treatment, which you may not have known about, to viral infections, and today we're going to talk about that.

3:37 Just to give you a background, it was actually first discovered in the mid-1960s, how many people walking in the face of the United States right now know about thymus alpha 1 and what it could do for them if they are worried that they're going to get sick or if the feel a sickness coming on or even if their sick and they can use it and again this was developed in 60s by a guy named Alan Goldstein as part of thimus and fraction 5 and in 1977 TA1 was finally purified as the act of a component exhibiting 10 to 1000 times the activity of crude thiamus fraction.

4:09 A synthetic form called thymalfazin or the trade name Zadaxin was developed for clinical use and has been approved in over 35 countries across the world for various indications. And it's endogenously produced by the thiamic epithelial cells and present in other tissues like spleen, lung, kidney, and blood at lower levels. Again, when we talk about endogenous peptides, thimusalpha-1 is another endogeneous peptide that although I couldn't really find any data around this, we would venture to guess as we age because the thymic gland shrinks and does not perform as well, that there would be lower levels of it.

4:45 Hence, we could potentially, whether we're using it for an acute issue or not, supplement with thimus alpha 1 periodically just to receive some systemic benefit again with our immune system and with the thyme and gland. When we look at regulatory, thymicinophiline was actually an FDA orphan drug. It was designated for malignant melanoma and chronic active hepatitis B, D George syndrome, and hepatocellular carcinoma in the U.S. Like I said, across the world, it's used in over 35 countries and has approved as a drug there in a lot of cases for chronic hepatites B and hepatite C

5:21 and as general immune enhancer in immunodeficient states. And it's not broadly FDA approved for common use in the US, but used worldwide in treatment regimens and clinical studies for immune related diseases. Again, I think too, we'll hint at this when we talk about autoimmune disease. Diamond top one is absolutely something. It wouldn't be the only peptide I would use for sure, But it is something that we can work to modulate the immune system, especially when you have an overactive immune systems. Let's look at the innate immune activation mechanism behind TA1.

5:51 It exerts its effects by broadly modulating the immune system through multiple molecular and cellular pathways. It interacts with toll-like receptors, which are called TLRs, on immune cells and binds to TLr3, Tlr4, and Tlr9, then triggers downstream signaling through IRF three and NF kappa B pathways which activates immune responses. And through these TLR mediated effects, TA1 activates dendritic cells and natural killer cells, which are crucial components of the innate immune system.

6:24 All of that scientific jargon and fancy language to say that thymus and alpha one is stimulating the body's natural immune defenses. It's not working as necessarily like an anti-fungal and anti microbial and antiviral. it's up regulating our body innate defenses to help our immune system fight off whatever's out there. And I think when we think about the concept of disease, and we think about this model of sickness and infection and illness, you can kind of think of it in one of two ways.

6:56 And one being, okay, I need to have a direct counter attack to whatever is going on, or two, i can actually give my body the tools to now be in a better state to fight off whatever infection or whatever virus or that is causing my illness. And I think when we look at that, long-term, we're going to be much better. One, because we are not going have the side effects of some of these drugs that may do things, for instance, like antibiotics. They may the intended effect, which is killing bacteria, but what else is it going do to the body?

7:27 And you could extrapolate that across multiple drug classes and multiple drugs for different sicknesses. When we look at Thymus and Alpha 1, we're going to the foundation and we go to foundation of the immune system and activating that immune systems so the body can heal itself. And ultimately that's what we want to focus more on. Let's look this T cell enhancement and adaptive immunity. So first we have T-cell maturation. Thymosophone stimulates differentiation and maturation of T cell precursors in the thymus by restoring depleted T-cell populations in immunosuppression.

7:59 And then we have a TH1 response promotion, which means that it skews immune response toward TH-1 profile by elevating interleukin-2 and interferon gamma production, enhancing cell-mediated immunity. And then we have enhanced cytotoxicity, which means that thymicinophiline boosts natural killer cell and cytotoxic CT lymphocyte responses, forming stronger antiviral and anti-tumor defense mechanisms. And again, instead of trying to attack a virus or attack a tumor directly with a drug, we are actually improving the immune system.

8:32 And there's also why we'll talk about this later. It's approved as an adjunct to some of these things that are anti-tumor, chemotherapy, things of that nature, and we will talk that. Let's look at its antigen presentation and antiviral effects. How does it cause viruses to go away? Thymosinoph 1 upregulates expression of major histocompatibility complex class 1 molecules and beta 2 microglobulin on cell surfaces.

9:02 What that means is this enhanced antigen presentation makes it easier for T cells to recognize and eliminate infected or malignant cells. And again, I know that sounds like a mouthful, but basically what ThymusNelphin1 is doing is making it easy for t cells, to recognise and to eliminate the infected and malignate cells and again if we think about this as a signalling molecule, we're upregulating the ability to do things so that the body can actually go and do what it does best, which is get these things out. It also, fun fact, increases intracellular glutathione levels, it also creates an antiviral state that reduces viral replication,

9:40 and higher glutathiol levels have been linked to inhibition of influenza virus replication demonstrating the peptide's indirect antiviol mechanisms. Again, indirect, but still powerful nonetheless. And when we talk about glutothione plus, that's enough of one. That is a powerful stack for immunity. A lot of people know glutathione is more of like a detox thing for the liver, which is true. But if we raise glutothione levels, it's going to help the immune system. Again, do what it does best. Let's look at immune balance and then also some of the anti-inflammatory properties.

10:11 Thymosophone can induce mechanisms of immune regulation that prevent overactive inflammation. By activating TLR9 on dendritic cells, TA1 increases expression of something called Indoleumine 2,3-Dioxygenase, IDO. But basically what happens is that Thymosinophil-1 stimulates pathogen clearance and tumor surveillance. And then by promoting regulatory T-cells in IL-10 production, we have inflammation control that prevents harmful hyperinflammation and cytokine storms,

10:41 which again, then feeds back into a healthier immune system. Again, you wouldn't think of thymosinoffil 1 as necessarily an anti-inflammatory peptide, but because of the cascade of things happening in the body, it is having an antioxidatory effect. Let's look at some of these anti-tumor effects. And again, people love to talk about peptides and cancer and causing tumors and everything and whatnot. To that, I will say, okay, yes, it's theory versus practice.

11:11 Yes, you could say that basically like when we're saying that I'm not disagreeing with those people, but it is like saying Mountain climbing leads to death or can result in death. Yeah, obviously, but it can also lead to physical fitness. It can lead, to improved enjoyment in life. Do I go mountain climbing? No. But people do that and they're perfectly fine if they know what they are doing. I think we say that about peptides. Yes, people that mountain climb are putting themselves at risk for injury, But it doesn't result, in injury.

11:45 And so when we talk about peptides causing cancer, it's kind of like saying, well, these pathways are causing certain things if we max out that pathway, but maybe a peptide is not even doing a fraction of enough to even stimulate whatever is happening there. Now let's look at the anti-tumor and antioxidant effects. Thymosophone demonstrates direct anti-tumor actions. It can inhibit proliferation of certain cancer cells and induce apoptosis, which is the death in tumor cell lines, including leukemia, lung cancer, melanoma, and breast cancer.

12:15 There is evidence to show that it does that in those specific diseases. It also increases activity of antioxidant enzymes like catalase, superoxide dismutase and glutathione peroxidase. And by reducing oxidative stress and DNA damage, it creates an environment less favorable for tumor growth and protects normal tissues from inflammatory injury. Again, I would tell anyone that let's say you're quote unquote at risk for a tumor or at-risk for cancer. Thymosophil-1 not only is directly go after those things if they're present, but it also creates the environment, the body where they are not going to

12:50 be good. which means I think it's smart to use cyclically through the years to add to quality of life, life extension, health span, you name it. Because again, it is creating an anti-inflammatory environment in the body to which those things can't really take a foothold. And then even if they are there for whatever reason, because of your lifestyle or just things that you may be genetically predisposed to or whatever, is going to kind of reverse that environment. Again, does that really well. Let's look at some data around cancer immunotherapy and hepatocellular carcinoma with thymacin alpha one plus the treatments,

13:25 which are called Linvatinib and centinalimab. People had a 16 month overall survival with this hepatic cellular carcinole and only 11 months without. And again, They still ended up passing away, but on average they lived five months longer. They also had a 55.8 objective response rate versus 34.7 in the control group with the regular medication in addition to the the only had a 34% response

13:55 rate versus the thymus and alpha 1 plus the regular medication at a 55.8 response. And then three years survival rate post operative hepatocellular carcinoma patients with thimus an alpha one had 68.4% three year survival rates versus 49% without the treatment, which when we do the math, that's about a 20% increase in people that lived longer. That is statistically significant enough to me to say, hey, okay, thymosophone above and beyond whatever this person was doing is statically significant

14:29 in helping reduce, recover, and hopefully eliminate cancer. and then an unresectable advanced hepatocellular carcinoma, adding thymus alpha-1 to the treatment significantly improved patient outcomes without adding any sort of significant toxicity. Let's look at melanoma and solid tumors. Thymis alpha 1 earned orphan drug designation for advanced melanomas due to its T cell enhancing effects. Clinical trials in non-small cell lung cancer showed improved overall survival when added to chemotherapy or radiotherapy.

15:00 And pilot studies in metastatic renal cell carcinoma indicated immune-related tumor control benefits when combined with existing treatments. Again, I think that's what's interesting is that in a lot of cases, dimosomal 1 is serving as an adjunct to kind of serve as immune system booster. Does it mean that it is directly responsible for the cancer? No, but it's at least giving the body a fighting chance. Beyond direct tumor response, TA1 reduces chemotherapy toxicity and improves quality of life. And I would tell people, chemotherapy has to be something that you and a family member decide on for yourself if that's what you're gonna do.

15:35 I can't really speak to that, I don't know enough. Family members that have done chemotherapy, is that what I'd have probably done? Probably not. However, it is devastating to the person and it basically takes their life and again the question is like well is it better to do that to not who's to say but it makes that person miserable and when we look at supporting the immune system with diamonds and alpha-1 they experience higher immune cell counts fewer infections less neurotoxicity and better performance status And by mitigating chemo-induced immune depression, thymosinophiline allows better treatment

16:08 tolerance and potentially improved outcomes. And again, if you are going to go that route, which again has got to be everyone's individual decision, I would at least take them as an alpha one to help with it. Let's look at some viral infections. We have hepatitis B and C. In the 1990s, TA1 plus interferon alpha achieved 40.6% complete response in HPV patients with 26.5% that just had extended interferons alone. There we see a 15% increase in the response patterning from just the standard medication for hep B and hep C.

16:43 And then again, it was confirmed in meta-analyses. Combination therapy of TA-1 plus the approved treatment for Hep B & Hep C outperformed interferon alone and achieving viral suppression. With advent of direct acting antivirals, TA1 use has declined but remains valuable in special cases. Again, I think if we can extrapolate that, not everyone has hep-B & hep you know, compassion for those people that do. But if we look at some of the viral load that people may be under, how can we use thymus and alpha 1 to defend it?

17:13 I think it gets really, really underlooked when we talk about using it. Let's look HIV and AIDS. Thymis and Alpha 1 has been investigated as an adjunct therapy for HIV infection, particularly in patients on Anti-retroviral therapy with low CD4 counts and while it doesn't attack HIV directly, it enhances T cell number and function. And clinical studies found that TA1 plus ART led to improved immune reconstitution with increases in CD 4 plus T-cell counts, and reduced viral load. Evidence shows stimulation of thymic output of new T cells as measured by rising T Cell receptor excision circles.

17:48 Lots of fancy words to say that people with HIV and AIDS, in addition to the treatment they're already receiving, the time is not for one helps modulate their immune system better. Now let's say it. Well, as of the of this being up, my YouTube channel is on up. So let us talk about COVID-19. And I'm gonna give you my thoughts on this. Early in 2020, Chinese clinicians indicated or it concluded thiaminzonopha and treatment protocols for hospitalized COVID-19 patients. The rationale was preventing T cell exhaustion and restoring immune balance. And some uncontrolled reports suggested TA1 could raise lymphocyte counts and help patients recover from severe COVID.

18:21 Now I have seen this play out in the real world. Yes, it obviously does. However, when we look at rigorous study results, a large multi-center COA study found no clear benefit of thiavinzanopha 1. After adjusting for baseline severity, time to stop one treated patients had higher non-recovery rates and mortality. Results may reflect confounding factors or that late intervention during cytokine storm doesn't reverse the course. Now, what I want to talk to you about is let's look at COVID and let us look all the other treatments that the standard approved COVID vaccine.

18:53 They were all basically manipulated to show that they don't do anything. You can look Ivermectin, you could look whatever else out there That was not the vaccine was manipulated to look like that. It didn't help. Now, again, people don't know about thymus and alpha one. People don' want to inject things. So thimus alpha 1 was never going to be something that was taking hold like ivermectin was. However, in practice, thamus, alpha1 had a massive benefit, anecdotally speaking, based on the experience of people that I know that were suffering from

19:23 COVID or whatever you want call the whole COVID debacle. Point being is that Thymus Alpha-1 absolutely helps boost the immune system to which if someone is suffering from COVID, is it going to solve everything? Is it gonna cure everything. Maybe, maybe not, but at the very least it is going help the downstream processes that boosts the system, to help body fight off whatever it. Again, there's other peptides that are outside the scope of this video that you could add on to Thyrmus Alpha 1 to really help with COVID. I never really made anything around that because I didn't want to get kicked off of social media, which, hey, it ended up not really mattering,

19:58 right? But I think when we look at that and we looked at the data around it, like everything else, there was kind of a blackout on some of these alternative therapies that help. But there is, even in some those studies that were used in China, evidence suggests that it helped. When we look at sepsis and critical illness, small trials in China reported that adding TA-1 to standard sebsis care significantly reduced mortality, especially deaths from multi-organ failure. The 28-day mortality was around 9% lower in treatment groups. And then in the large British Medical Journal study in 2025, it failed to show significant benefit.

20:34 However, the hazard ratio for death was essentially one with authors concluding no clear evidence for routine septis use and meta-analysis suggest potential benefits in high-risk subgroups Probably with low active immune systems and research may clarify specific populations like immunosuppressed substance patients could benefit from thymus and alpha-1 therapy. Now, I wanted to put this in there because when you start to look up data on dimosanalpha-1, what you will see is that it, quote unquote, enhances the vaccine response. Now you could probably imagine how I feel about vaccines.

21:04 You could imagine what I think about the vaccines, however, there is evidence to suggest practical use of dimsananf1 as a vaccine adjuvant to improve immune responses, particularly in populations with weaker immunity, such as the elderly or immunocompromised individuals. Studies show elderly adults who received TA-1 had higher antibody titers and seroconversion rates to flu vaccine compared to the vaccine alone. And also it's been used to improve responses on patients on dialysis or with low immune function, helping non-responders achieve protection in hepatitis

21:34 B vaccines. Now, why do I talk about that? Okay, so you look at the nature of a vaccine and this is not about vaccine. I actually hate talking about vaccines because it really does no one any good because we fight over the same things that don't really matter. I'm so politically polarized, which I can't stand because it's like, I don' care politically about anything, right? But When we look at the immune system, what is going on with a lot of people's immune systems in response to vaccines? It's over-activating the system which causes a lots of these bad responses that we see.

22:07 Thymus-alpha-1 acts as an immune-system modulator, meaning that it helps bring the immunity system back into balance, which is why in the case of vaccines over taxing the immune system and causing bad responses, it works is because it brings that immune modulation back into balance. Now, the reason I even wanted to put this in here was not to talk about vaccines. It was to about, well, if it does that nicely with vaccines, imagine what it would do without vaccines? It would actually do the same thing that we are trying to get out of vaccines which is to protect ourselves from illness.

22:42 And again, vaccines don't necessarily raise the body's innate defense systems. In a lot of cases, it will suppress it long-term, as we've seen in the last five years. However, Thymus Alpha 1 does do that. And I wanted to put this in there because you're probably already on board, if you are watching this video, with not getting the flu vaccine, right? But you could go to your mom, aunt, uncle, brother, sister, whoever, and say, hey, instead of getting a flu vaccination, maybe take some Thymos Alpha-1 and see how it does. Take your shots, take the shot of Thyrmus Alpha One and not the Flu shot.

23:15 But if you have someone that is gung-ho on getting their flu vaccine every single year, like some people are, you can say, hey, we used time to send off a one. And in my opinion, it's going to help reduce some of those negative side effects of which there are many that come from vaccines. Again, I point this out to say that For goodness sake, if someone's going to take a vaccine, at least give them thymus and alpha one with it. But hey, maybe let's try thimus alpha 1 to get the same intended effect, which is immune protection and immune surveillance andimmune strength that will

23:45 serve us to stave off whatever it is we're trying to stay away from. And I wanted to point that out because it does come up in the data that it actually enhances vaccine response, Which makes sense because if you look at Vaccines and what they're doing, they are over-activating the immune system, which causes that, and Thymacinophil-1 helps bring it back in balance. As far as dosing goes, what you could do is I would just say for standard chronic dosage, it's going to be a 1.5 milligram subcutaneous twice weekly dose. This is what was used. They actually use 1 .6. I don't know where they got 1 6 instead of 1 5, but it was using hepatitis and cancer trials for six to 12 months.

24:19 Peak plasma levels reach one to two hours with a two and a half to three hour half life. For acute illness protocols, short-term intensive regimens like sepsis or COVID-19 or the flu, I like 1.5 mg once or twice daily. I don't think you need to go over 3 mg daily total. Usually 1,5mg twice a day seems to work well and whenever I get a sickness or anything flare up early this year I got a cold because I was traveling a lot. And that's what I was doing. And it definitely helped lessen the severity of the cold.

24:49 Again, it's one of those things you may still get sick, but the question is how sick? Is it sick to the point of being knocked out for a week? Are you good in one or two days? Or does it prevent you from going to hospital if you have COVID or whatever? And then cancer adjuvant dosing, they will do one and a half to 3.2 milligrams twice weekly during chemotherapy or immunotherapy cycles. Some melanoma studies use one milligram per meter square twice a weekly, which equates to around that depending on the person's body size. There you can see that the dosage is kind of where you need it to be.

25:21 I think if you were just using it for immune balance, you're not sick or anything. One and half milligrams, two times a week, totally fine. If you feel like you're getting sick or you are sick, one and a half milligrams, two times per day is good. And then again, if you were doing chemotherapy, that's typically what they're doing. You could probably even go a little bit higher, but I don't think much higher. At least in the data that I see is going to have any sort of outside benefit to that dose. One of the most attractive things about thymus nalpha-1 is its strong safety profile.

25:52 Again, as a naturally occurring peptide, endogenous in every human body is generally well tolerated, even with long-term administration. The most frequent side effects are ejection site related. Now this one, most of time is gonna sting a little bit. You'll get local irritation, redness, or mild discomfort that typically resolve quickly. And systemic side-effects are very rare. and again, because it's a immune modulating peptides, we're not really having like a histamine response or anything like that to this. But there's no significant organ toxicity or severe adverse events reported in trials. The main contraindication is hypersensitivity and caution and deliberately immunosuppress patients like organ transplant recipients where immune activation

26:28 could theoretically increase rejection risk. Again, very rare case, but just be careful there if that's What is, just to sum up the clinical evidence, again, there's 35 countries with approval, 68% survival rate for hepatocellular carcinoma patients versus 50% controls, and 40% response versus 25% in the hepatitis B and C patients. And the current body of evidence spans preclinical experiments, clinical trials, in real world use. Again, we have a lot of human data on this.

26:59 For whatever reason, other countries seem to think it's way better than the United States does. Go figure. But just for future things, look for large control cancer trials. I think it would be good there. Viral disease applications. Obviously, I Think if you know whether or not we're going to get that in the mainstream, who knows, but we could use that for ourselves in The research world. And again, just looking at aging and immune senescence, i think again when we look at endogenous peptide production over time declining in people, we Look at anti aging, when you look At the immune system, using thymus and alpha-1 alongside thiamylin would be really good for cellular senescence and

27:32 anti-aging purposes. But when we look at it, just think of thimus alpha 1 as an immune system modulator. If you are immunosuppressed, it's going to help bring up the immune to where we need it to be. if you're autoimmune or over-activated immune, which is a lot of times what's happening in auto-immune disease, will help to bring it back into balance. So again, help modulate the system It does that amazingly well. It really helps people from a variety of angles, but especially when we look at those use cases.

28:03 And that is it for the slides. and there you have it folks. That is the 2025 update to Thomas and Alpha 1. Hopefully it was helpful, entertaining, and even informative and educational all at the same time. But I think again, when you look it, it's so powerful and so good to use in so many different use-cases. I want to make this video right now, just timing wise, because again, we're heading into that flu and cold season. Don't go down to the Walgreens or the CBS and get their procedure there. Get some thiaminacin alpha-1. Use it prophylactically, meaning that you would use it beforehand.

28:36 If you feel like a cold is coming on, or even if you're sick, get some and use them because it usually will help mitigate the risk. of getting sick, but then also when you're sick getting the illness to become more severe. I love Thymacinophil-1. It is absolutely one of the peptides I keep in my house at all times. No questions asked because you never know when it's going to come up. And again, I think when we look at the use cases, they're so far and wide. I think what we will probably see into the future if I had a crystal ball is more people gravitating towards using this periodically, not necessarily for any sort of illness or anything, but just to protect themselves.

29:08 Again, a lot of times I'll even use it before I travel, knowing that my immune system is going to be suppressed from traveling, from the lack of sleep, and from bombardment of EMF, which I didn't even get into. But I thought myself the one's going help with all that. Again, thank you guys so much in closing. I just want you to know I have the best audience in the world. The people, the amount of support that I get from you, guys, it really makes this a dream come true for me. To know that what I'm doing is helping people and whatever platform it is, wherever the information gets out. It is truly an honor and a blessing to bring this to you guys.

29:39 So thank you so much. Whatever you do to support, whether it's just watching this, it is liking, commenting, using my code on things, helping share it with a friend, going to the Dropbox video or the Spotify feed, sharing that with the friend. That's how we get this information out there because this will never be picked up on the mainstream. Maybe I'll get my YouTube channel Mac, maybe I won't, but it's not gonna be data that gets picked up by the algorithm and just naturally put out there. It really will come from the groundswell of you guys helping share this. And again, it not about me, or how many followers I have or anything like that.

30:09 Its about sharing this information and making people's lives better. So in closing, thank you, guys, for doing that, I love you and I will see you in the next one. Peace.