My Day at Fountain Life and a Peptide Discussion with Dr. Bill Kapp

0:09 Hey everybody, this is Hunter Williams. I hope you're doing amazing wherever you might be in the world. Today I have a little bit of a different video, but I promise I think you are going to like it. Now a couple months ago, a company called Fountain Life reached out to me and they had seen some of my videos on peptides and wanted to talk to be about potentially integrating peptide into their membership program and I started to look into them.

0:39 I was like, wow, this actually seems pretty cool. And the more I dug into him, I'm like wow. This is a company. It's actually backed by Tony Robbins and Peter Diamandis. They have an amazing medical director. His name is Dr. Bill Capp. and I start to do more research and was wow this is really cool they do very, very interesting diagnostic testing. If you know me, you probably know I am not the first person to jump on board for every diagnostic test because I think a lot of times Some of those may not necessarily lead us astray, but they may cause more worry than they do good.

1:13 But the more and more I spoke with Fountain Life and talked to some of their doctors and talk to the people that work there, I was like, wow, this is a really cool program. They wanted to bring me in to help them understand peptides better for their members and how to get better access to peptide for the members. But in doing so, they also wanted me to go through their membership program and really experience what it was to be a member. So what I'm going to do in today's video is actually show you a video of me at their facility in Orlando, Florida.

1:44 They have a few different facilities around the country, but I actually went through the first day as a member in their program. And I want you to understand this is not a paid advertisement. I am helping Fountain Life. integrate peptides into how they work with their members and in return they are showing me their membership program and how it looks and what it Looks like to go through that and the process we're going to be documenting what I go Through as part of that membership Program so today's video it's going to be twofold. It's gonna be first about 10 minutes of me going through their diagnostic program.

2:16 So if you're watching the audio version, you may want to watch the video version of that for those 10 Minutes. And then the second half is going be about a little over an hour long. And it's actually a podcast with myself and the medical director and CEO of Fountain Life, Dr. Bill Kapp. And what we do in the podcast is we go deep on the history of peptides as well as how to best use peptide today. But then also where peptids are headed in future because as you guys have probably heard, it is going to maybe get a little bit weird with peptidies in

2:47 a future. I think everyone is gonna be okay. In 2026 it might look a bit different than it has looked in past. So that's what we cover in the podcast. Overall, this video will probably end up being somewhere around an hour and a half. So a little bit longer than most of my videos, but I think it'll be valuable nonetheless. And as we head into 2026, one of the things I'm going to be focused more on doing is doing guest podcast interviews where either I interview podcast guest or I go on other people's podcasts and talk about peptides.

3:18 I promise I will still do my solo content where I am doing deep dives on different peptide hormones and things of that nature. But as I continue to grow my content ecosystem and I'm investing heavily in doing much higher quality video content and audio content, part of that will be having other subject matter experts in and around the field of field peptides and hormones to bring to you guys to not only bring a different perspective, but then also to kind of have a one plus one equals three effect to where we bring another amazing mind in the world of peptide.

3:48 I bring my unique area of expertise just from the research world, and we combine those together to hopefully make really, really good and informative content for you guys. So sit in, strap up. Today's gonna be a little bit different. The first 10 minutes, again, I recommend watching the video. You can still listen to the audio. What I'm gonna do is take the 10 minute of myself going through Fountain Life's membership program, the day one where they walk me through all the diagnostic testing. And what I'm gonna continue to do over the course of the next year as I make more content with Fountain Life is to bring to you what is revealed through

4:22 my testing and then what plan maybe to with some peptides to address, if anything, that is found in that testing. And I actually got back the first round of test results and I think they were good and they're actually pretty interesting that confirmed some of things in my own personal medical history that peptide have really helped address and hormones have helped really address Going forward again. This is not a paid advertisement or anything like that I hope that watching through watching this you become acquainted with fountain life and maybe end up reaching out to them But by no means am I pushing that or something like I just want you to understand that they have an amazing membership program

4:57 that really does a lot of good things for their members in terms of helping them understand their own health and and helping them build a personal dashboard where they can evaluate their blood work and their MRIs and all these different things that we do from a diagnostic testing standpoint into one place. What was really cool for me to see is that all of the testing that I did with the four hours that i was there doing my testing on the first day would be seven or eight different places that I would have to go to specialist and go into all these very unique fields of medicine to try to get into one place.

5:33 And they're able to do that in one that you can also then see on a dashboard that also interacts with AI to help you better understand your results. Obviously there is a very generous and very welcoming hand holding component with the doctor and with medical professionals at Fountain Life. That's it for this one. As always, check the links down in the description. I'll have the email list and then some other info about Fountain Life down there. But strap in, I think this is going to be a really cool one, and I'm going take you through the Fountain Life diagnostic process and what that looked like.

6:06 And then I will lead into the podcast and we're going talk about some really things with Dr. Bill Capp in a podcast. Hey, what's up, guys? It's Hunter Williams. Hope you're doing amazing wherever you are in world. You probably notice a little bit different of a background and camera setup, but I am actually here at Foutain life in Orlando, Florida. Hey guys, I'm here at Fountain Life. Just walked in, it's 7.07 in the morning. We're getting started early. Hey, good morning! Still in The Center Director, welcome.

6:36 Hunter, nice to meet you. Nice to be here as well. It's really cool so far. Sounds like we have an action-packed day. we're gonna do some diagnostic testing to get some health markers and everything, so. So, Welcome to Fountain Life! Oh wow. Gonna be having an amazing day set up for you, a lot of discoveries. I feel like I am in a future. Yeah, there you go. So to start with, we'll have you change into scrubs. It's just to make sure that there's no metal bits on any of your plumbing for any is the imaging.

7:08 We'll you go ahead and take a look at the menu. And this is your call button. Just ring whenever you're ready to get started. All right, so lots of healthy options here. Maybe try to stay away from all the sweet stuff. I don't know everything yet that I'm going to do, but I am really excited. It looks very legit, very very advanced. Really cool, the setup here is amazing. The hotel that I come into is right next to the building. So you just walk over and get started early in the morning.

7:38 But so far it looks really cool. I'm excited to learn more from some of the people I am going to be working with today about some diagnostic testing around longevity and some those parameters that you guys love to look at and keep up with as we are aging. All good? Good? Yes, yeah, good to go. We'll be starting with the MRI, so that'll the longest portion of your testing. All right, sounds like we're gonna be doing the MRI first.

8:08 Get that out of the way. I think I've only had one MRI done before. They're very loud from what I remember. Don't know if that's how they are now, but this one will be fun. With the M.R.I. you get a lot of pretty cool data that you wouldn't be able to see otherwise like on a blood work panel or something of that nature. Hey, good morning. How you doing? I'm Hunter. Nice to meet you. All Right, thank you I had one, it was probably like 12 or 13 years ago, back when I played college football, and it's just like C for an injury there,

8:40 so. You'll be in scanner for about an hour. Okay. Through the tube. The first 40 minutes is dedicated brain imaging from head down. that one while holding your breath several times. The last 15 minutes is dedicated brain imaging. So we go back, take a look at your brain, some detailed imaging to collect information for possible abnormalities like aneurysms. And we'll also collect some 3D volume data that we send to AI for a brain health report.

9:15 Hey, how you doing? I'm Hunter. Nice to meet you. I am Chris, I will do your bone density test today. All right. This test is going to measure the strength of your bones to see if you're at any risk for a fracture. We'll do a body mass index at the end of this test. And we're also going measure them out of fat you have in your body. Okay. In regular fat. Thank you Have a good day. Hey Hunter, nice to me too. Hey, how you doing?

9:45 Good. Hunter. Nice to meet you. Just go ahead and sit down. First thing that we're going to do in here is going be an EKG. It's going give us some information about the electrical activity of your heart. Get your blood pressure next. So I mentioned that the CT scan of your coronary arteries is a little different from an MRI or a regular CT scans. So this one involves the use of iodinated contrast dye. Okay. It's a clear liquid substance that's going to go through the IV that I'll place in your arm and it's gonna just help highlight everything on the scan.

10:16 Now we'll do the fun part where I stick you and place that IV in you arm. We have a pretty comprehensive panel here. Most people come and they set their record for the most vials. I mean I've had like pretty extensive blood work done, but this is This might be the record so our next step is gonna be actually going to our IV lounge as we call it Okay, you're just gonna. Be getting normal saline So that's just going hydrate you and it's gonna help flush the contrast out of your system later It's a pretty big needle that

10:47 we use just because we have to use that contrast dye and One of the things I'd love to look at is like inflammation and like metabolic health. So like when you look in aging, a lot of times we look it inflammation, and then where someone's metabolic help is that because that's going to dictate the common buzzword now is inflammation aging. And so like how much inflammation you have dictates like the rate at which you're aging so pretty common things like, you know, fasting insulin, A1C, but then also things, like HSCRP, homocysteine, A lot of those markers are going to tell how much inflammation's in the body and

11:21 then what we can do about that. I'm sure there'll probably be, I mean, you'll know better than me. All of these are gonna be. Yeah, lots of inflammatory markers, metabolic markers and your male hormones. We do a very extensive cholesterol panel, so we're looking at different particles of cholesterol, small, big. I actually am excited to see that because I've done like a couple small particle cholesterol tests, but not, I know there's way more that can be done. So with my background, like in the peptide world and how that integrates with a lot of this stuff, you know, get blood work done and we get all of these

11:53 markers and everything. But then a of people kind of, it's like, well, what do I do now? Where do go from here? And what I'd do with. My lifestyle. What I would do from a supplementation standpoint. Even a peptide standpoint in the blood work will dictate a lot of like, okay, based on that, these certain peptides would be a good fit or a Good thing that someone could use therapeutically to help address whatever it is that comes up on the Blood work. But I think, you know, in a Peptide world, that's like all the rage right now, right? Like if it's on The tip of everyone's tongue, like different peptids. A lot of people don't get their blood work done and they just kind of jump into doing stuff without having a comprehensive background on the data of what's

12:30 going on inside of their body. So doing something like this, especially with how extensive the panel is, is really good just to get insight into one, where you're at today, and then how to build a plan around that for the future. And sometimes if someone's 40 or 50 years old, took you 40 to 50 to get to the point where you're at, it doesn't reverse in three weeks. You can't do a peptide plan or a workout plan for three week and expect a lot of it to reverse. So getting as much data as you can as a background for your plan is really helpful.

13:03 I'm excited to see everything that we have. We're all done with the blood work. That's the hard parts out of the way. All right, we're good. All right, we're good. We're going to go to the right. Okay, so we are going come right in here. So this is our IV lounge. I'll have you take a seat at this first chair here and make yourself comfortable so the chair does recline in the inner right. So this is gonna be pretty quick in terms of getting the fluids infused into your arm less than 30 minutes.

13:35 I'll check in on you and then when you're done, you will have the option to either wait in here or you can head back to your suite and wait for the CCTA scan, okay? So today we're going to do a scan of your lungs, which is kind of like a 3D scan, like chest x-ray with a CAT scan machine so we can see it in all planes.

14:05 And then we are going do scan your heart, first we will do calcium score which will look to see if you have any calcium build up in any of the arteries. After we do the calcium score, the nurse is going to come in and give you some nitroglycerin and the nitro glycerine is gonna open up your blood vessels as large as they can be and then I'm gonna inject you with some iodine and iodide is a contrast agent that makes us be able to see your arteries.

14:38 Hello. Hey. So congratulations. You are all finished with today's testing. Um, so you have some time to kind of relax, enjoy your meal, get changed back into your normal clothes. Whenever you're finished, just press your call light and I'll be in to walk you out. If you need anything in the meantime, Just let me know. Okay. Sounds good. It was a pleasure meeting you. Congratulations. Thank you And that's a wrap. It's been an amazing experience. It was really cool.

15:08 I'm excited to talk more once I get my results back to go over with you guys, to show you what it's like to be a member here. Because I think when we look at all the things that we do, right, we optimize our hormones. We use peptides to improve our metabolic health and improve injury recovery and those things. Those are great, but if we don't have a baseline to really understand what we're working with, All those things aren't going to matter as much because we don't have the pieces of the puzzle to put them together. So that's what I'm excited to do is get my data back and go over that with you guys and show you kind of what was found through the diagnostic testing

15:43 and then also to how I might alter or implement new peptide protocols or new things going forward from a supplementation standpoint as I get more and more involved in my day. And what's really cool too, I'll talk more about this is they end up building basically like a personal health dashboard for you where all of this data goes into one place to where you can access it on an app and they have an AI interface called Zory that you look at all your data and as you get more and more data through the years of being a member, you actually can compound that and figure out how to map where your health is headed and really optimize

16:20 your personal health, because that's what it's all about, right? We can have these blanket generic prescriptions or generalized protocols, but when we get the data, it allows us to build personalized health outcomes. So I'm really excited to get this back and share it with you guys. I can't recommend it enough. It's been amazing and I'll be talking much more about this. But basically that what's it been like at Fountain Life so far and stay tuned for much to come. If I had like a crystal ball, I would say like that class of medications for longevity purposes will become one of the greatest things that we have ever.

16:58 And then even in the short term, what it's doing for people's health that I've witnessed firsthand from like reducing high blood pressure, reducing cholesterol, how would diabetic drugs end up improving heart health? That much as because it is taking that metabolic burden off of. Hello everyone. I'm Dr. Bill Kaplan, the co-founder and CEO of FountainLife and your host today for the conversation here with Hunter Williams.

17:32 We're going to explore breakthroughs today, technologies and forward leading strategies that are really helping to shape the future of longevity and performance. I'm really excited to introduce Hunter here today because his work is really pushing the boundaries of what we can achieve in preventive and optimized health. And particularly, he's a peptide expert, which is an area that we're very interested in here at FountainLife. We have some peptides we offer, but we really want to increase that offering and really be able to scale that. Hunter is a respected educator, remarkable and has a remarkable ability to take complex biological science and turn it into practical,

18:07 actionable, and accessible information that for anyone really who's looking to elevate their health span. He's operating at the leading edge of therapeutic peptides, hormone optimization, metabolic function, in the evolving science of performance longevity. Through his podcast and courses and online communities, he's helped tens of thousands of people understand how to strategically leverage peptides, hormones, and intelligent lifestyle to improve their wellbeing and extend vitality. This is a conversation worth paying close attention to as we, Hunter really helps us get some insights into this really unusual area of peptide and particularly

18:45 a rare blend of scientific rigor and real world application. So it's a pleasure to welcome you and thank you for being here. Thank you. Dr. Cap. It's, uh, privilege and honor to be here I know just from talking before we started, we're going to geeking out a lot today. So I'm really excited and Thank You for having me here This is a total blessing. Well, glad to have you here. It's really exciting. This is our first podcast, so we're excited to... Oh, wow. Thank you. Yeah. So we are here to bless our podcast studio.

19:16 And then more importantly, hopefully launch us on being able to provide information. Really our goal here is really educate more than anything else. We do a lot of really cool things at Fountain, but really what we want to do is educate the public about what's available. I think that's super important. So, um, what I'd like to do is segue a little bit because, you know, a lot of our fountain life viewers, uh, be hearing this for the first time and they may not be familiar with your story and how you wound up as a biohacker because it was out of necessity. Right. And so maybe we could talk a bit about your history and then we can kind of delve into what you've discovered along the way.

19:50 Yeah. So growing up, I'll make it as short as I can, but I always tell people before I remember I wanted to be a professional football player. I don't remember a time where I chose that. Hey, that's what I did. And that what's I want to do. My parents didn't push that on me. Obviously my dad played football in high school or whatever. But they even said like before, you know, when I was three years old, I would like to be banging on the TV, like football games, You know when? I Was a baby and so for me, i was just always an athlete and to me that was everything You, know like in high school when kids go to party or whatever

20:24 all i cared about i had like one focus and that Was to go, to college to play football so that i could go To the nfl because that, was my passion in life And I did really well in school, but I always tell people like the only reason, not the reason like, the, reason I didn't well, in-school is because I wanted to play football. And, I knew like if I, didn' get a scholarship to, play, football, like I'd have a backup plan to go walk on somewhere. That's ended up what I ended doing. So played high school football, ended walking on to the football team at Wake Forest University because I was able to get some financial aid to go there and then got a scholarship and started there for three years.

20:55 Ended up having a pretty successful career. I by no means like All-American or anything like that. But for me, it was like validation because that was my dream is to play football especially in the ACC because i'm from North Carolina. you know, what my dream was as a little kid. And so for me, that was like validation. I played linebacker. When I look back, there were times when I was eight years old, 15 years, 22 years to where I would have some of these hits that were just insane. It's like where you kind of don't know what's going on. and I never diagnosed with a concussion because back then there was no concoction protocol.

21:28 It was like, you got your bell rung and you either knocked out or you're good to go. And so I grew up doing that. I remember looking back, there was one time in high school where I got hit in a game. It's like a playoff game and the next three weeks I had AP US history, which was in like AP or pre-calculus or something like that, and I remembered trying to do my homework for weeks after that game, I could not sit down. Every time I would try to my do homework, my brain would just throb or whatever. I was like, okay, there's probably something going on here, but also to my livelihood depends on me being good at this game to like be able to pay for

22:02 my college. You know, my parents weren't going to play for college and like to, to make it in life. And I. Okay. I'm not going say anything. So anyway, go through that similar things happen in college, you know where you have hits that are just like man, like. See your life flash before your eyes. I remember one time we were practicing, we're about to play Notre Dame my senior year. And so for me, as like a kid that grew up being a football fan, this was like everything. It was, like, I get to playing Notre dame at Notre Dame my Senior year, you know, go out there, rank like number three in the country. Remember the Thursday practice, which is usually like walkthrough practice.

22:34 Um, I remember a wide receiver ran across the field and I just didn't see him and we like ran into each other and he went down, he like pretty much like blacked out. And I had just got up and remember thinking like, Oh, like couldn't C straight. I was like don't let them see that something's wrong with me because I didn' work for 16 years to not get to play my senior year at Notre Dame, even if we're going to get our butts whooped. Like I wasn't going let that happen, you know, and be a captain and do everything that I wanted to do. Um. And so that's just how it was. And, so graduated, like wanted to make it an NFL, didn't make the NFL.

23:08 After that, got into working in real estate and I was like 24, 25 years old. I started to notice like, I'm eating like very healthy. I am training, you know, not like an athlete, but like, very similar, like staying in great shape. And my health is just not seeing there. Like my mental health was not good. It was kind of like depressed and anxious. So I was like well, maybe it's just, stress from work and life and figuring life out when you're in your twenties. But it just kind hung around and I never felt right. As like I don't feel like myself and have never.

23:38 Felt like this. Anyway, thanks to through like we were talking about Dr. Mark Gordon earlier. And I realized that there could be an association, which at the time I didn't know anything about testosterone levels. I was like, I'm a football player. Right. Used to run into people for a living and, uh, between testosterone, levels and post or traumatic brain injury and concussions and heard them on a podcast. And, well, let me just like go get blood work and find out like what it would be.

24:08 Luckily, was in the care of a great doctor at that time. he was able to put me on testosterone therapy when I was 27 years old. Um, and so I've been on that sense and it completely changed my life. And then being in the hormone world, uh, that kind of gets you interested in other stuff like peptides. So I started researching peptide and learning more about them and learn more those. Then, um, fortuitously just like started publishing stuff online, just talking about it and talking my personal experience. That led me to coaching people and you know, doing what I do today.

24:38 But, Um, yeah, it kind of came out of necessity because I was like, Hey, I've got to fix this problem in my life, which is that like I don't make as much testosterone as I should. And that led me into that. The peptide world. Then you realize once you get into, that there's like this whole other world out there that had I gone to like a regular doctor, he probably would have said, you need an SSRI and you probably like Cialis or Viagra or something. And luckily that's not what happened.

25:08 I had a good doctor and he took me through tests and everything to make sure everything was okay. But unfortunately that what we're up against is like that would have been the pathway of matching the symptom to the drug versus like actually optimizing and healing the root cause. So this journey from kind of where you went into the peptide world, let's talk about that a little bit, because I'd like to talk a bit about where peptides are today. And there's a lot out there, you know, obviously, but we should, maybe for some of the people that are going to listen, talk to them about the history

25:39 of peptids, kind where we think they may have started, and we know they've got a long-standing history outside the US. and then kind of where they are today. And then I'd like to get into some specifics about, you know, different stacks and things that you might find really interesting and the things you think people should definitely look at. Which ones are legal and which ones aren't? We'll kind evolve into that. Yeah, for sure. I love peptides. Obviously, I talk about them all day. If you go back to the history, my best guess would be that insulin was probably the first like widely Discovered and synthesized peptides.

26:11 I don't know exactly what year that was. We're probably going back a hundred years ago or more We had insulin to be able to help people with diabetes. So that the example. Hey, here's an exogenous Peptide that we can take to use to heal disease now, that's obviously we have way better things than that now to Help people that are diabetic. But to go to your point Peptides, most of them were actually born a lot out of Russia. And if you look at the Cold War in the United States and Russia, in Russia they were kind of forced to figure out some of this stuff to be able to like

26:46 either help their soldiers or their space program or whatever. Then even when we had Chernobyl, which was the nuclear disaster that happened, I've actually talked to people that are from Russia that were born out that they had to figured out a way to heal some radiation poisoning. And so a lot of the peptides that are now becoming mainstream in America actually have been used in Russia for 70 or 80 years. There's even some of these peptide called bioregulator peptids, which are very short chains of amino acid peptidies that in some cases are actually bioavailable orally,

27:18 so you can take them oraly. Um, that were born out of the Kevinson Institute, a guy named Dr. Victor Cabinson, uh, was kind of. The mastermind behind a lot of these peptide protocols that came out Russia. So when we look at clinical data, A lot people will say, well, like, Hey, we don't know about peptides, right? Cause it's a gray area. They're not FDA approved. And we do have a lot of data on them, maybe not so much human data in the way that we typically would for like a Prozac, but we have lot a data that's either in Russian that hasn't been translated into English or just other countries that have used these Um,

27:53 just to give you an example, for instance, one peptide called thymus and alpha one, it's kind of considered an immunity peptides that's approved in 35 countries, actually as an adjunct to chemotherapy, because when you do chemotherapy it suppresses the immune system and thimus alpha helps stimulate the system. So it actually, whether or not you believe in chemotherapy. It actually improves patient mortality outcomes for patients that are using chemotherapy because it helps support theimmune system, which is obviously so. press from chemotherapy.

28:23 And so in the United States, that's not FDA approved, but in 35 other countries, they see it's good enough to another good example would be cerebral Iosin. That's a peptide that it actually is derived from pigs. If we think about peptides, like people are very familiar with taking like organ extracts of an animal. Like we have desiccated beef liver extract that you can go buy on Amazon. A lot of peptides are derived in similar ways and cerebral isin is derived that way from porcine material and actually it's common practice in a lot countries

28:57 in Eastern Europe to keep cerebralisin on an ambulance so that if someone has a stroke, they immediately administer an IV of cerebral Isin to help with any inflammation that would come in the brain as a result. of the stroke. So, peptides have a much longer history than people realize. In the United States, they've probably been around the way that we think of them. For like the last 20 years, you started to see like compounding pharmacies that were making them, like your BPCs and your GB500s.

29:29 started doing that about 20 years ago. You kind of had like this whole research world that kind sprouted up as a result of that, that was in a lot of cases like compounding pharmacies, just selling them out the back door. So kind like populated the underground in the bodybuilding community. And there was kind a grassroots movement there. But now you've seen it obviously take hold of mainstream medicine because When doctors look, like I've talked to so many doctors, including yourself, that really care about the patient, or they say like, hey, I have someone that has a torn labrum on their shoulder.

30:00 Do I want to give them surgery or could I potentially heal this with a non-surgical intervention? There's overwhelming I guess we would have to call it anecdotal because we don't have like PubMed studies on it. There's overwhelming anecdotally evidence to say like, hey, I had a patient that took this and it prevented them from having surgery or it helped them heal in half the time that they would've normally healed with their surgery. So contrary to like what might be like popular that people would see online, peptides have been used going back tons of time. And just now that we're talking about it, there's a peptide called DCIP, which is called Delta Sleep Inducing Peptide.

30:35 That was actually studied all the way back in the eighties for opioid withdrawal. And so what that does is a peptide that stimulates, uh, deep sleep to raise your Delta wave sleep when you're sleeping. But through doing that, somehow it was discovered in eightie that it would prevent severe opioid withdraw symptoms. So you had people coming off opioids and they could actually administer this peptides to where it calmed their nervous system down. and prevent some of the withdrawal symptoms. So if you do some digging, there is a lot of data, but as we well know, we're kind of up against, you know a bigger side of the equation of an industry

31:12 that might not want to necessarily heal some of those root causes because, like you said, some those prescribed drugs are pretty entrenched monetarily and financially. Well, they're part of culture, unfortunately. It's interesting. I think I was listening to R.F.K. Jr. recently speak about the U.S. consumes 90% of world's opioids. Wow, that's great. Prescription opioids, right? I mean, I was telling people, we're one of the two countries in the world that allow you to advertise drugs online.

31:43 Yeah. Everybody else has kind of banned it, but the drugs are all for symptoms. And I wasn't joking with my wife because we were watching, she likes to watch the Hallmark channel Christmas. There was a drug there for which it was for what they call OIC. Everything's got a nice little acronym, opioid induced constipation. And I'm like going, okay, well, you probably shouldn't be on the opioid at the first place, but now we've got a drug when you get constipated, we take that too. So what we're finding, and we see this in our Fountain Life patients, people come in and a lot of times they're on 10, 15 medications.

32:16 And once again, it's one drug to chase the symptom. But yet we have these things like peptides, which are normal peptide. A lot of them are normally constituents either found in other species or in your own human body. These are things that your body just makes and it just stops making as much of it or for whatever reason. And then we can't give it back. right? Because there's no, quote, double-blinded study through the FDA. So, let's talk a little bit about, you know, I mean, first of all, outside the U.S., obviously, these are widely available.

32:50 In the US, what is widely-available and which ones, and then, obviously we have the ones that are, research-grade only, which is kind of just a way of kind-of get around some of the F.D.A. regulations. But, of, the one's that you're familiar with here, one of things we're very interested in at Fountain Life is, providing a a cache in an area of peptides that will get in trouble necessarily, but at the same time being able to offer those as an adjunct optimization.

33:20 I think the first and probably the class that most people are familiar with now is the GLP-1 peptide. Those are huge. And I'll say like in our longevity community, probably in the last couple of years have viewed those more in a negative light because of some of the media around some the side effects that come out of them. And so when we look at those, it's like, okay, well, let's look what's really going on here and let us drill down to what is happening. So on one side of things, you have physicians that are prescribing GLP-1 peptides, which would be like your Wigovia, Ozempic,

33:56 ZapBound or Monjaro or the names for Terzapatide. And you have physicians that are prescribing them. And in order to maximize insurance reimbursement, they're escalating the dose way faster than you would actually need to get a therapeutic effect to help a patient lose weight. there's been a lot of bad press around those peptides because people haven't treated them in the right way. What I like to tell people is they're more a catalyst to create weight loss and change in people's life than they are a lever,

34:30 meaning that you just hit the button and the weight comes off, right? And you can do that, but you're going to have pretty bad consequences. But when we look at it from a longevity perspective, if we at like, okay, what causes aging the fastest metabolic dysfunction is going to cause inflammation that leads to aging and chronic disease. And if you look what GLP ones are doing at the right dose, administered the way and without being like overdosed and not as an adjunct to lifestyle intervention

35:00 and also other interventions like hormone therapy, if necessary, like other peptides that are endogenous to us because even though they're very similar, you don't have terzapatite in your body. Or it's like a BPC you actually have, we all have in our stomachs. But I think when you look at what they do from a metabolic health standpoint, as it stands right now, they One of the best, if not the longevity medicines that are available because they help stem the tide of inflammation. Meaning the metabolic dysfunction that leads to inflammation that causes aging.

35:34 They can help reverse that if you use them properly. The problem is most people, you know, they might need to lose 70 pounds. and they start at two and a half milligrams of Monjaro and then they go to five milligrams and the go out of 10 and 15 and look in their 25 milligrams. And they may have lost weight, but they've shut down their thyroid, they have stomach paralysis, their constipated and have all these issues. They can't eat enough protein, losing muscle and so they all have these issue. So I think for familiarity sake, The GLP-1s are some of the greatest interventions we have, but I would say, and there's discussion around what this means,

36:12 using them at a microdose periodically throughout the year is one of like the best longevity medications we had. And that could be if you need to lose like 50 pounds or even if don't need lose any weight, What I've seen in myself and a lot of the people that I coach that are on these that have them prescribe from their doctor is nothing but improvement in lipid panels, which is crazy relative to like statins, what it does to, you know, all the catastrophic consequences of statin. Improvement in inflammation, improvement in chronic pain, reduction in alcohol consumption, all these other things.

36:46 And there was actually just a study that came out in October of this year that of all of metabolic associated cancer, which I think is 40% of diagnosed cancer is associated with metabolic dysfunction. All together, there is a 17% reduction when they control for every other variable reduction risk in that cancer in the last 10 years for people. And when we look at that, those are not really people that are changing their lifestyle. They're really just injecting whatever the doctor tells them to. And they're still eating the same thing.

37:17 I think it was 86,000 patients in that analysis. When you look that and you have a 17% reduction in cancer, and then even some sub-sex, in ovarian cancer there was a 47% percent reduction. there's something that's going on there with those that we're just like scratching the surface of. And I think in the next few years, hopefully we figure out a better way to implement those intelligently rather than just doing the same thing we've done with every other drug, which is like give people as much as you can and get them hooked on it, you know, as long as, rather using it in a cyclical manner

37:54 and also using at a much lower dose than people probably think they need. Well, I love to hear you talk about that because I think that they are one of the longevity drugs and I we're going to see this. Interestingly, at the age-related drug development conference that was just in Copenhagen, the CEO of Eli Lilly was there. Oh, wow. And he basically stood up and he said, semiglutide is the first longevity drug. We believe this at Eli Lily. I think you're totally right. The doses are way off the chart.

38:26 I can tell you, our data at Fountain Life has been really interesting because what we have seen is it crushes liver fat. Because we measure everything, as you know, because if you can't measure it, you cannot manage it. But one of the things we do is we look heavily at what people's liverfat is. And literally, 26% of our members, and by the way, we a fortunate group of people that are able to come in and go through testing and can afford it, and we're going to democratize it over time. But 26% of you elevated liver fat.

38:56 And these are people who know about diet and exercise. Literally, when you put them on GOP1s, it crushes their liver of fat to well below 4% in a very short period of time, And so it's probably going to address that. And then as far as the ovarian dysfunction, PCOS, Polycystic Ovaria Disease, which is one of the biggest problems we're dealing with, and people talk about it being like type 3 diabetes, right? It's blood sugar inflammation issues. And so blood sugar is the number one inflammatory substance in your body, whether you bring it from the inside or when you get it,

39:32 for instance, as you age, your hormonal decline happens, right? And particularly males, testosterone level drops, muscle mass drops which is your number 1 glucose sink, and so you're going to wind up with higher blood sugars over time. And that bloodsugar we believe long term is what stimulates this whole inflammatory cascade. So I think it's a great drug. And I you're right. I there are a lot of ways that we have to get around that one. In terms of getting people dosed on a microdose, cycling, like every other part of your body, I it is super helpful.

40:04 Outside of GLP-1s though, what's the next one you would recommend or that people should really be looking at? Because there's lots of things, obviously losing weight is one, another thing I should mention is that there is some really interesting data around cognitive improvement. on GLP ones as well, right? So people who have early stage cognitive decline or have just seen, you know, really big improvements in that, particularly with things like dementia. Yeah. Another class of peptides, and there's a bunch of different ones in this class, some are FDA approved, Some are not, is the growth hormone peptide class.

40:36 So you'd have growth hormones releasing hormones and then growth hormonal releasing peptids. For all intents and purposes, both of those classes of peptides or hormones work to help the body raise its natural growth hormone production. And what I always like to tell people, because if I'm like building out a comprehensive plan or working with someone to do that, a lot of people are like, okay, well like I can take a GLP one, right? But don't I have to like keep upping the dose? And the answer is no. In a of cases, like we want to use the GL P one as a catalyst, and then we can actually use some of these other peptide.

41:10 To. increase our metabolic health on a completely different pathway through a complete. Different mechanism that is contributing to the same goal, which is obviously longevity. And we look at that, like for instance, one would be Sarah Morelin. Another one wouldn't be Tessa Morel and Tess Morels a little bit stronger. Both of those are growth hormone releasing hormones. What they do is they stimulate the pituitary gland to go through bunch of processes, but basically raise the body's natural growth. And if you look at growth hormone and IGF, what happens is after the age of like 25 or 30, that just falls off a cliff.

41:43 And then we get into our forties and fifties, and we really don't have that much left. Some people may or may not as kind of variable to the individual. Uh, but I know for me, like going back to a pituitary function, That was another thing alongside of my testosterone that was also impaired. because the pituitary is involved in that process of producing growth hormone. And also growth among peptides made a massive improvement in my life, particularly for me, like with my sleep, because if you have lower growth from on it affects your deep wave sleep. If you raise that, it can do it.

42:14 What's cool about the peptide is as opposed to exogenous growth, hormone administration of like bioidentical growth. It's sending a signal to the body to make more of it as if we were young. So it's raising that, um, now you still have to use intelligence around those because you wouldn't want to, use too high of a dose for too long. And if we raise growth hormone too much, there could be some like downsides such as like insulin resistance and things of that nature. But when used intelligently, and if you were to like use a growth, hormone hormone or peptide alongside of GLP one, all of the sudden now I'm retaining

42:45 more muscle. I'm burning more fat via a completely different pathway than the GLP. And so I can stay or use a lower dose of that GLPs and then also get all these other cool benefits, which is better sleep, usually better hair, better skin, but her nails. Then also to easier to build muscle if I am weight training and easier, to burn fat if you know, living healthy. And so that's another class that I think should be kind of like one of those things that, like, as we age, that should kind be like a stock consideration of, okay, let's look at that first in blood work and different tests.

43:17 And then what can we do to improve that? And when we look those peptides, some of the data is pretty cool around what they do with visceral fat, improve deep sleep, and just overall make us healthy. So do you need to cycle those? Cause there's some people say you should cycle these five days on, two days off, or, you know, just cycle. I mean, what are your thoughts around that? Because I think, more is not always better. And I, think people forget that the body does need some recovery time. What do, do do recommend for people? I'm a big fan of cycling those and a lot of times too, I actually would recommend cycling shorter cycles than maybe even some of the pharmaceutical prescribing

43:55 guidelines around those. So for instance, Tessa Morell, and it was originally developed for men with HIV lipodystrophy, which is where they get, you know, really nasty visceral fat around their midsection. And if you look at studies of that, I think it's within, quoting off the top of my head, but within six months, like over half of the people develop anti-drug antibodies to the peptide, meaning that the body is having kind of this innate immune response to a foreign substance. It's not bad, but basically like you inject something foreign to body, it's going to start to build up tolerance to it as with pretty much any medication.

44:30 And the benefit of cycling is that one, we can take like an eight or a 12 week window where we're using that peptides. to get all the benefits that we want. And then we cycle off of it for, you know, usually around the same amount of time that I was using it. There's a couple of benefits to that. One, we avoid any sort of the negative side effects that would come from like elevating growth. So a lot of people get concerned with like growth hormone and cancer risk growth, hormone, and increasing insulin resistance.

45:00 When you're cycling, you kind of pulsing. And so you are going up and then the body is coming back to homeostasis. We harness these benefits without chronically elevates the hormone that we wouldn't want necessarily elevated for a long period of time. There's, there's that benefit. And then there was also to the benefit of keeping the body sensitive to it. Meaning that if we're developing these anti-drug antibodies to what eventually will happen is that you will have to increase the dose over time. So maybe that doesn't happen for someone for a year.

45:30 Maybe they could stay on it for year and get benefits before they have start doing it, everyone's going to be a little bit different. But when you cycle, you're maintaining sensitivity to the peptide. And so it allows you to harness the benefits and then resensitize yourself to it and stay in a healthy range without having to worry about escalating the dose to which, not that this would happen in every case, but in some cases there could be bad, like a lot of these have like parabolic curves, right? There's like, a therapeutic threshold dose. If you go too high, it falls off a cliff. So I'm a big fan of cycling and also to, It allows people to like get familiar with it because I think a lot of times when we're using a peptide,

46:10 the best way to explain this is through an example is like we get accustomed to it. And so people will use a GLP one and I'm a fan of cycling GLPs because it's the same thing. So they'll use it for a year and then they come off and now they're ravenously hungry. And I always say, well, like, let's think about this for a second. Are you ravenously hungry? Are actually just going back to where you were before, but your body became so accustomed to blasting this one pathway, which is the GLP one path way that all of a sudden you've like dysregulated your appetite a little bit now and you don't know what it feels like.

46:42 And I think when we look at cycling, it helps guard against that. So even if we took the sensitivity issue out of the equation, It allows people to get really familiar with their body and have a sample size of like, okay, I know that this peptide is going to have this effect, but I don't want to like get so accustomed to that, that my body necessarily becomes like in need of that all the time to, like have the intended effect. So let's talk a little bit about it. You talked about Tessa Moreland and Sir Morelan, and those have been around for a while and obviously available, legal, off label indications that we may

47:18 want to use them for. What about some of the ones that are not, quote, legal, but they're kind of in this gray zone, like CJC 1295, Ipamorlin, there's a bunch of these. I mean, you know, and then, what are your thoughts around, which of those are, first of all, the FDA is hot and cold, one day compounding pharmacies can't make them and the next day they can make him. And so we're kinda waiting for clarity on that. But what, are you thoughts, particularly things like CJC, because a lot of people really like that and it's got great function and great ability.

47:52 Yeah, I'm, a big fan of them. Obviously the FDA is not. There's actually, it was September of 2024. They came out with this list and it's called the BULKS list. And there was probably like 20 of the most popular peptides on there. I am quoting off of memory, but it is basically like as the FTA, we advise guidance against prescribing these because there's not enough. Human data. Well, I've probably seen more human data just anecdotally coaching people that are using these than like what you would see in a published study that gets approved for something. Again, that is not like clinically rigorous enough, but in practice, of CJC and when you see CJ C 1 2 9 9 5 no DAC, what that means is that it's actually

48:34 just CJ. There's another version that has something called drug affinity complex on it that extends the half life, which a lot of cases you don't necessarily want for a growth hormone peptide because you want a pulse, which means you like want to raise it for short window and then have it to like return to baseline levels. I'm a big fan of both of those. And I can talk about two of like, so CJC exists. It's like seramarylin and testamorylin on the growth-hormone-releasing hormone side of things. Then ipamrylin is a grow hormone- releasing peptides.

49:04 And all that means to say is that they work slightly different from a pathway standpoint. So if a Morellan is a ghrelin agonist, which means that it tells the brain to make more ghrelin, then causes more of a growth hormone release. Whereas CJC, Tessa Morellin and Sarah Morellen, they are a Growth Hormone Releasing Horman, through a couple of different pathways that is different than the ghrelin pathway to release growth hormone. And what happens is you get this one plus one equals three effect, because you hit two different path ways in the brain to reduce growth hormones.

49:36 You get more of an effect than just taking double the dose of one of them. I really like CJC when we look at it from a, an effect standpoint, because it's a little bit more mild than Testimone and Testimonial is pretty strong. And so a lot of people, it works, but they might get bloating, they make it water retention. Um, where CJ see, you don't see that as much, and it pairs really nicely with it around.

50:06 So again, not FDA approved is obviously on that bulks list. But when you look at it in practice, I've seen time and time again, people, usually those are like gateway peptides. So it's kind of like their first foray because they're pretty much, you can't say nothing is side effect free. They're relatively side-effect free, they are easy to use, and almost everyone, young, old, man, woman, benefits from them. So I'm a big fan of those. I like the pairing of two different ones together because it hits two slightly different pathways to get kind of a synergistic effect.

50:42 You can't get that through most compounding pharmacies. Where do people get them? And then where do you get it that they're safe? Because one of the things we know is China has flooded the peptide market through all kinds of different areas, making sure what you can get if you got it online. Where's the quality control? I mean, it's one thing when you have a compounding pharmacy that's regulated, you know, and at least we know that they're atleast checking the bulk substances. But, there are people that will sell these online and you don't always know where you're getting them.

51:12 And so, where do people source those? And I'm not looking for an advocating this. I am just saying that we now that people are getting these. So, if they are geting them and they determine to get them, You know, you could go overseas and get them probably and try to bring them back in the US. But what would people do with those? I mean, where do they source those yet? Here's, here's kind of the misnomer right now is a lot of times you have the compounding pharmacy world, which obviously if you can get from there is great because there's a chain of custody around the whole manufacturer manufacturing process.

51:43 Some compounders I've heard they're like, Hey, we're not going to play around with us. We're done with them. I heard other ones that they've built. several, like a hundred million dollar businesses on making peptides, whether it's GLPs or growth hormone peptide or whatever. And they say, Hey, we're going to roll with it until maybe the regulation changes and kind of roll the dice and say like, if the enforcement doesn't come for us, We're gonna keep doing it. So you could go that way, but you know, like it's obviously kind of dicey, it like, hard to find and it out there.

52:13 Now we look at the research side of the world. That's like a good chunk of market where people are buying from a website online that says for research purposes only. And the thing with that is that the website is selling it. They're indemnifying themselves and saying, Hey, we're selling this to you. If you use it, that's on you because we told you not to use as a human. This is not for you to us as human now. Does that mean that all of them are bad? Not necessarily. What gets kind of weird is that as far as I understand it, there's no raw material peptides made in the US right now.

52:45 And so all of the raw ingredients to make peptide are coming from China. In a lot of cases, that's even the case for compounding pharmacies. They just have a chain of custody of like where it's made and then like how it gets synthesized here in US. It's the same thing with research peptids. All the raw materials, to my knowledge, come from China, and then they're either made here in the US or they are made in China and sent here. So what people have to do, again, I'm not advocating for this, but if you're going to go that route, please be extremely diligent in your research around

53:15 purity and quality testing. And so what I tell people is like, Hey, if you're going to go that route, there are third party labs that you can send samples of these two. So take the money. If you could invest in peptides, take money, send off a sample and make sure it is what it says it. And a lot of cases, the worst case, I think they're just getting like. you know, sugar in the vial. So there's not like, you have, I've really seen a lot of stuff that is like negative reaction. Ironically, have seen like a lotta cases where people have negative reactions from stuff at compounding pharmacies, maybe more so than the research world.

53:48 But there is, like it's an unregulated market and much like cannabis was 15 or 20 years ago or these other things that are out there, there are people that were out they're doing it. I always tell people like Again, to go to the idea of being the CEO of your own health, take that in control, test for purity and quality. It might cost a couple hundred bucks, but at least you know. And then also if a company is selling those online, if they're reputable, they are going to offer those for you. So they will have them third party tested on their own. And they're going to say, Hey, look, this came back with no endotoxins, no lipo polysaccharides, No sort of impurities or anything like that.

54:24 It is what it says it is. And yeah, you have to take that at face value if you're relying on the company provided, but reputable ones will do that so it's one of those things like. people are going to do that. You know, like obviously in a perfect world, we'd be able to get a prescription and walk down to Walgreens on every corner in America and be about to, you know high quality peptides. Um, in my experience, most of the companies are trying to the right thing for people, but it's also one of those things, to like Ronald Reagan said, trust, verify and trust it, also do your homework and verify it because You know, it's just like anything else.

55:00 And I think I read a study, not to, like say that, you know all peptides are good, but 80% of the supplements sold on Amazon either don't have what they say they have, or they less than their advertising. So it is kind of same thing, just know who you are buying from. Like all the supplement that I buy, I know they are from reputable companies that do third party testing. Same thing with like any peptide that get access to is I'd know where it comes from, how it tests out, and I am regularly looking at those things. So it's tough because, you know, like we'd love to be able to tell people like, Hey, there's an abundance of compounding pharmacies and there there is

55:35 no issue with it. But unfortunately the world we live in now, it is kind of, well, the challenges, I mean, they're just not a lot of companies that are going to spend the hundreds of millions of dollars to take these through testing. And the reason they are not is because even if the evidence is there, uh, You know it, is very difficult to keep somebody from making these, Uh, on a black market, so to speak, if you will. And then, uh, once again, you know, like I have a very good friend of mine, he used to live in Belize and you would hear he was on testosterone and, it was just going through all kinds of rigmarole to get testosterone, get his doctor to prescribe it and everything else.

56:09 and down in Belize, you just walk in the grocery store and buy it off the shelf. So, I mean, this was the, and he was like, it's exactly the same because it was exactly, the manufacturer, exactly same vial. And yet, we vilified testosterone for years in The United States because of the bodybuilding community and some of abuses. All of things that they told us, is going to cause prostate cancer, It's going cause heart disease and all this. It turns out, None of that was true. Just same thing with women's hormones.

56:39 So I think, look, buyers need to be aware, obviously, and there are different ways. Trust but verify. I that's a great thing to think about. Let's talk a little bit else because one of the things we're really focused on at Fountain Life, when we talk about optimization, not just the hormones and obviously getting growth hormone up, which is super important, But it's metabolic health. So I want to talk a little bit about the mitochondria, which is really the power plant of the cell. You know, we all remember from high school biology, right?

57:09 I mean, this power plan of a cell and what we knew about them by mitochondrion then, you know 30 years ago versus what know today is very, very different. And now I know and we'll talk, we should talk about some of the peptides that are available now and some that have just gotten recent FDA approval. And then, you know, so let's talk a little about the mitochondria and how critical that is and what these peptide are that available. Yeah. If you look at, like a lot of things in the body, natural processes through environmental stress, through aging, all those things decline over time.

57:40 Mitochondria are a big piece of that. particularly when you look at oxidative stress on the body, impairing mitochondrial function. So that could be environmental and me could mean that like we're exposed to bad food, bad water, you know, toxins in the air, pollutants, things of that nature that causes oxidate stress. Too much exercise causes oxidative stress. If you tax your mitochondria too much, the too-much exercise, that's going to have a negative side effect. And so when we look at mitochondrial basically being those power plants, if we're throwing too in there, think of like throwing a wrench into them,

58:12 you throw enough wrenches into then eventually They're going to stop spinning and they slow down. And because of that, kind of the energy cycle in the body, looking like the electron transport chain, ATP, and all these things start to slow it down, but what happens? Practically speaking, we get fatter. We get sicker because that's starting to show down so what's cool is the peptides. we have things that can address that. There's a really cool peptide. I've been a fan of it for a long time. It's called SS 31. This is actually another endogenous peptide. So we all have SS 31 walking around in us.

58:44 And as we age, of course, those levels decline. But what SS31 does is it binds to cardiolipin and then by doing so improves the actual structure of our mitochondria. When we look at someone that's aging, like I said, keep throwing wrenches into it. They're going to stop spinning and everything gets jammed up in there. What SS-31 is, it actually is remodeling the hardware of the mitochondrial. And it was actually, it's funny how like drugs and peptides work, right? Because there were these guys and they were working on people with mitochondrial myopathy, another syndrome called Barth syndrome,

59:20 which is a genetic disease. And that's originally where SS 31 kind of came from a drug pipeline. standpoint, but along the way, it kind of made its way into the research world. And then people said, Hey, well, if it helps with mitochondrial health, that could probably help with some of these things. Then we start to find out that it. Clean up reactive oxygen species. So it helped someone like that oxidative waste byproduct that's building up over time. Um, actually just recently got approved for Barth syndrome. And the dose I think is like 40 milligrams per day intravenously.

59:51 What's cool is that for someone that might not have Barth syndrome, which is obviously a severe genetic deficiency, you can use a much lower dose to get this therapeutic effect of remodeling the mitochondria. And so the same way as like maybe testosterone or estrogen declines with age, mitochondrial function declines with age, especially relative to our environment. And we can use a peptide like SS31. I think SS 31, what's cool about it is I've talked to so many people that have used it.

1:00:23 There's not necessarily what you would say is like this, like super turbo charge effect or anything. Like you're not going to take it and feel like. Superhuman, but what it does the same way that a lot of like mitochondrial health agents do is improves the function, remodels the hardware of the mitochondria and in doing so allows all those processes to work a little bit better. So what'd you'll notice is if you use SS 31, even at a low dose sleep just gets a bit. Better. my exercise gets a little bit better. Even in my studies, they like, it's something crazy.

1:00:54 Like the aerobic capacity goes up by like 30 or 40% in aged mice when they're using SS 31, even in human trials for a bar syndrome, there's their six minute walk test goes off. I think something like 15 or 20% when are using that because it is improving the robo capacity of the mitochondria, which ends up leading to all these energy related things. So, um, It's really cool. And when we talk about like aging and longevity again, You know, we have GOP ones, right? But do we need to use those at a high dose or can we use like a tiny dose? And then we had, Hey, like, here's a time dose of SS 31 that improves mitochondrial function, which is going to clean out some of the oxidative byproducts

1:01:30 and the RLS in the body. It's going improve energy efficiency. And it's gonna like help you sleep better and all those things that kind of just feel better. There's use cases actually in like chronic diseases forts, chronic kidney disease. massively helps people with chronic kidney disease. I've seen people, this is just like anecdotal, but I have seen with like a GFR of like 55, you know, that are like right in that range. Like in eight weeks, like double their GF R and get it up on SS 30. Yeah. Just with SS 31, it does a lot.

1:02:00 And again, This is like, anecdotals. So like there's not published studies or anything, But I seen guys like in their eighties take it and their PSA drop from like nine to two. Okay. It's improving mitochondrial health, but what in the world is going on that it's like in a matter of like, you know, six months. That's interesting. I think that's an interesting point because I, think one of the things, there's the Warburg effect, which is really highly tied to cancer. And so it is mitochondria dysfunction. So whether we're talking about senescent cells and mitochondrion dysfunction, or we are talking cancer cells, mitochondrian dysfunction there is kind of

1:02:34 a theme here. So, by the way, now that SS31 is FDA approved for one indication it can be used off-label, is it going to change the availability? I mean, if somebody is going lock down the ability and block that from other compounding pharmacies from being able to make it? You know, I hope not. And I. If you look at the name of the company that's on it, it won't name names. It doesn't start with an E and end with. So it seems the companies with the largest legal defense funds are the ones that are basically in this battle.

1:03:09 I say, and if you. The owners of that, don't remember specifically who owns that one. In a way, I think it actually brings more attention to like a smaller pharmaceutical or biotech company that has that. And maybe it makes it like an acquisition target for a larger one, but I hope it brings. Attention to it because when you look at like peptides, we'll say like, okay, well, if someone's coming into the peptide world, they're going to trust probably FDA approved. more and so it's like, Hey, well now I can use that off label. And then I think with SS 31 relative to like the GLPs, which have so much street cred and media cred, everything was like SS who's talking about SS31.

1:03:45 Right. So like The more we can get it out there, I hope that's the case. Maybe that does happen eventually, but it kind of like whack-a-mole if you look at it. It's going to be this battle like back and forth of Okay. Well, we have SS 31, but now there's MOTC and now these other mitochondrial peptides. We should talk about MotC because that's been around a little longer. And what are your views on MotsC in terms of versus SS-31 in term of one versus the other? I love MottC. Another works distinctly different than SS31 mechanistically.

1:04:18 Um, but still has like a really good effect. I'll say MOTC is probably again, another endogenous peptide that declines as we age. It has much more of like, a performance enhancement benefit for people, meaning that like. You know, someone might take SS 31, they may or may not feel anything, But you get their blood work done six or 12 months later after cycling it a few times, and you're going to notice something in most cases. Uh, whereas M.O.T.C. Most people within, you know, a very short time horizon are going to notice like, man, my energy is like through the roof in a good way.

1:04:51 You know? Like I have like better insulin sensitivity. And again, to go back to GLPs, like if people just had a GLP plus a little dose of a MOTC, what they would do for fat loss, because Motsi is working on the mitochondria, then you have a bit of GLB stimulation is so powerful. And it also, too, a lot of times when people are taking GLPs, those are so powerful at inducing a calorie deficit to help people lose weight. What happens when we have a calories deficit without a GLP?

1:05:21 We get tired, right? Because we don't have as much food and we're burning more calories. Well, MATC helps kind of like bring that up because it improves mitochondrial function, which then raises energy levels, Which for someone that might need to lose, weight is going to, help them get to the gym. and do all of the lifestyle things. So I love it from that standpoint, but again, there's tons of data, especially around heart health of improving like cardiac function, improving heart tissue that's there. I like to tell people too is like, What's cool about like the mitochondria peptides, you can almost use like cycle Matzi and SS-31 at different times throughout

1:05:58 the year and get an amazing effect over time. Because what SS 31 does is it kind of, if you think about building a house, it's going to help repair the foundation. It's gonna fix the holes in the walls and Matzie comes in and it decorates it. And it makes it really nice inside. So it is more of a software remodel for the Mitochondria. I think people, just based on my experience, they get more like a performance benefit, meaning that they'll probably see a little bit more fat loss. They're going to feel it if they're exercising, like their VO2 max is going go up.

1:06:28 And so there's a bit of a performance benefit from that. But again, the difference between a pill and a poison is the dose because some people will do like 10 milligrams when I would recommend staying with like, you know, half a milligram or one milligram. And sometimes it can be so powerful, it actually can like induce hypoglycemia in some people or actually cause like a little bit of anaphylactic shock because it's so. Powerful. And again, where it was like SS 31, because of the nature of how it works, you wouldn't see that as much. You'd have to go probably to like, a dose to where we just become.

1:07:01 which was like MOTC, um, you can get to a like pretty cheap, depending on where you're getting it from dose that becomes like, wow, like that's like kind of making me like tachycardic or hypoglycemic because it's so powerful at modulation. Obviously, we're going to open a Fountain Life in LA sometime next year. Let's talk about the Hollywood community. There's no group that's probably more eaten up outside of maybe the UFC fighters with peptide stacks. You hear a lot about The Wolverine Protocol.

1:07:32 What are these common ones that you're seeing in really the celebrity community? Because they're the first to try everything and then if they find it, they really glom onto it. And we have some, you know, actresses and actors that don't look like they're aging very much, and obviously, it's not all plastic surgery. So, I mean, what are your thoughts around those stacks that they are doing, like Wolverine, for instance? Yeah. Yeah, so Wolverin would be typically you hear BPC 157 and TB 500. And I don t know who coined that.

1:08:02 It was one of the greatest like marketing in the peptide world, whoever coined it back in a day. But basically, that helps you heal much faster. What's taken off a lot is what you've probably heard of as the glow protocol, which is actually BPC, TB 500, and GHK, GH KCU, the copper peptide. And what's unique about those three things is when we look at inflammation, injury recovery, but then also, too, just kind of like an overall anti-aging

1:08:32 effect to skin health and hair health, things of that nature from a very aesthetic perspective. They're helping with angiogenesis, which is helping blood flow around the body. TB 500, that's going to be your BPC. Tb 500 is something with stem cell migration. So if you have an injury site, it's gonna help get stem cells to that injury side. But if your injecting it subcutaneously, its also just going help improve the amount of stemcells circulating in the And then you have GHK, which is like the GH K is one of the, or GH case, you is of like, the most multifaceted peptides because it works like at a DNA signaling level to do a

1:09:10 bunch of things that like helps with collagen synthesis. So primarily, like if you were going to inject it into. injury or people are injecting it into their face. That's going to help with collagen synthesis in those areas. But it's doing a ton of other things too. What's crazy is like, this is what I do all day is go and read stuff about this, is that there's actually evidence to show, I believe this isn't animal models, the GH KCU reverses emphysema and it's because at a DNA level, it going into those inflamed cells,

1:09:40 particularly in lung tissue and saying like, okay, the DNA is now transcribed to express emphazema. Let's wind that back and express a more youthful state. And so it was actually doing that. So counter to like what a lot of people would think is like oh, well I'm going to take the glow because it can make my skin glow. It's actually having a lot of these other ancillary benefits that people don't realize, which in tandem will probably make people look better aesthetically. But those three right there, what's cool about them is you can inject them into an injury.

1:10:10 So if you have like a torn shoulder or torn knee or something, you could inject in that area to help with repair, but you're going to also inject systemically just to helps with overall health and gut health, lung health. All those things that they're gonna help in the function of doing. I would say from like an aesthetic standpoint, whoever invented, you know, the Wolverine and now the, glow protocol, um, which is those three together. Um, it's amazing. And I think again, when we look at those, all three TB 500 is a fragment of thymus and beta four, Which is another endogenous peptide,

1:10:41 but BPC, that was in beta for GHK to you. Guess what? All endogynous human body. and from the time someone is 20 to their 60, their GH K levels are going to drop by 80%. And so you take, you know, a man or a woman that's 60, all of a sudden you help GHK restore back to youthful levels. Now what's going to happen? Their skin's gonna look better. Their bodies recover faster. So, um, pretty cool. And again, for people in the peptide world, they've been using those forever, but for someone that is new to this, it's amazing to like see them for the

1:11:12 first time, like say like, Hey, I took this and like, all of a sudden, like this like shoulder that I've had has been bothering me for years. Like the pains are starting to go away and help repair. And it's because we're giving the building blocks to be able to get some of those processes the body's trying to do anyway, but just doesn't have the tools. So, so let's talk about administration because one of the, there's a lot of controversy I mean, there are people with selling sublingual preparations saying, oh, you know, it'll absorb in, sub-lingually like we do other drugs and we've done that for years. There's others injected, they're oral forms.

1:11:43 I means, what are your thoughts? I obviously you're an expert in the field because I look at these and like, so for instance, BPC-157 is kind of one of those FDA ones where the FDA doesn't know. So they just, some people say you should get it. Some people said you can't, but obviously these are stacks. I mean, can all three be combined? Are they best injected? Or are they the best sublingual? What roots and what do you recommend, obviously, for people? Yeah, it kind of depends on what you want to use it for. So I would say like, okay, let's say that we have shoulder issues.

1:12:16 The most direct efficacious way is going to be to inject it into the site. Now that doesn't mean that you could take it like subcutaneous in the belly and still not yield some benefit. But if we're talking about an injury, usually a site injection close to the side, you might not want it directly into. Um, but close the sight is to help. And then when we look at some of those other ones, what I'm actually really excited about is companies right now that are working on bringing some those alternative delivery mechanisms into a way that's efficacious to some peptides, even those three that we just talked about BPC.

1:12:52 Okay. You can get some bioavailability orally out of them. Now, how much is it enough to help heal a shoulder? In a lot of cases, no, but it might help someone with gut health. So if they have leaky gut, you might get enough out it to prepare the gut lining, which is going to some autoimmune diseases in some cases. So there's that, but I think there are two that are really cool. One I know is that they've actually developed buccal mucosa, or I don't know if you pronounce it, buccal or buckle mcosa.

1:13:22 Yeah. Buccal. Is it what part of the country you're from? I'm from North Carolina. So we say buckle, you can put it on your tongue and then it sticks to the roof of your mouth and it absorbs systemically through the bloodstream in there. I've tried these before and although maybe the injection If the injections, you know, 100% 10 out of 10, I noticed that I get like 60 to 70% efficacy out. But then again, it's like, okay, well, if you have a torn shoulder, It might not be the best to absorb it that way because it was going to be like injecting

1:13:53 it into your belly to where it doesn't have the practical application. but for hair health, i've done a GHK buckle. administration before I wake up and the next day for me, like people at darkens hair because it's working to like help hair. GHK is, you know, a very powerful hair health help pet type. Um, for, if I get like a little graze in my beard, I'll wake him the day. And then my beer is like jet black, and then I will get more, my hair will start to get a bit darker. And so I know what's working. So although it's like, you know, if I tore my shoulder, it was probably not going to help as much absorbing that way.

1:14:25 There definitely is efficacy. And I've even tried like a CJC buckle, absolutely like improve my aura ring, sleep scores, help my deep sleep and everything on my or a ring. Um, and so that's an efficacious one. One that I'm really excited about, I actually probably going be trialing these soon is, uh, there's a company that has developed patches. that actually has micron needles that they have published data to show that you reach the same serum concentration levels as a subcutaneous injection. And it's actually needles, but what's cool about it is you apply the patch, you leave it on for 20 minutes and you take it off and it feels like you just

1:15:00 put a bandaid on, But there's small enough needles to where it can like puncture the skin to get efficacious delivery into the sub cutaneous fat tissue and then deliver. And what they've been able to do is pretty much synthesize every peptide that we have, you know, in the compounding pharmacy space or the research space onto those patches. So I'm excited to try those. And the reason is like, yeah, is injection going to be the best delivery system? In most cases, yes. but I was talking to the nurse earlier today who was doing my blood work in my IV.

1:15:32 And I said, I'm usually, um, fine with needles. Like I've never been bothered by needles, but, uh, how many people sit down with you and they start like hyperventilating and yeah, she's like 80%. And it's, like, well, you know, if 80% of people aren't going to inject something, what does it look like when we can get some of these things? Cause we could talk about the benefits of peptides all day, when someone's scared to. Yeah. They're not going to inject, let alone go out of their way to source it from a compounding pharmacy or the research world.

1:16:02 Um, so I'm excited for those, even if they don't work as good as the injections, just the fact that people can get the therapeutic benefit from them and say like, Oh, okay. Like I can use, you know, BPC or GHK and it works more than maybe like some like collagen supplement that I bought on Amazon. Not that those wouldn't. Work for what they're trying to do, but. I'm excited for those because this is hopefully going to expose more people to peptides. I mean, GLPs have done a pretty good job, right?

1:16:32 You know, I have like a hundred million people that have been using those. But I think it's going expose people. To some of the wonders and benefits of them. So we'll see where that's headed. And I can say like, okay, if I could wave my wand and get the most peptides to the, most people to help the people, you would have to find a way around the injection problem because you're always going to run into that where people just like don't want to. Well, we have a lot of people, a of our members, you know, they have them, but they don't want to, They're terrified to take them out of the country.

1:17:05 Yeah. Because then you got to them and then they're like, Oh, hey, what's this? You know? Yeah, yeah. And, oh yeah, You have syringe and you've got this unknown vial here. It's got a bunch of letters on it. You're just telling me it's peptides. Right. So I mean, this is the challenge. A lot them just don' take em. They are gone in the summer to Italy and they are off of everything. So I'd like to kind of wrap up and talk about peptides for cerebral function and neurodegenerative issues and, and neural function. So, you know, because we don't, we talk all the Wolverine stacks and they're really popular and you kind, the weight reductions and all that,

1:17:42 but you obviously neuro-d generative and Neuro-cognitive issues are huge. things like cerebral license and things. So what's available out there that people might find interesting and in things that they might be able to get? Yeah. There's a couple of peptides. These have been used in Russia for ages. Probably going back to the 1950s, there's published information in Russian. One's called CMAX. Another one's call Selenq or C-LENQ. Basically what those are, they're kind of like modulators of neurotransmitters.

1:18:12 I wouldn't say like a lot of people look to those as kind of like nootropics to like, Hey, so like I'm going to massively like enhance my brain function the way that someone taking like the stimulant would. And they don't really work that way because they help modulate neurotransmitter function. But when we look at neurodegenerative disease, healing inflammation in the brain is going So I really like those, not so much because you're going to get like these crazy effects from them, but just because like over time, it's one of those things that can kind of be like a background insurance policy on

1:18:43 making sure that we're minimizing. GLPs are obviously good because of not what they're doing to the brain. I mean, we do have GLP-1 receptors in the. But because, of what, they are doing from a metabolic level to stem the tide of neurodegenerative disease from like, you know, amyloid plaque buildup and all the things that come from that. Um, but there's two that I'll just throw the name out there because they really cool. And there was like some research being done around them right now. One's called J147 and that's actually an, it's an orally bioavailable peptide that you can take.

1:19:16 And what that does is it enhances mitochondrial function in the brain. So creatine is all the rage right now in our world, right? Because of the, brain health benefits, because it is increasing mitochondria function of brain, increasing the amount of ATP they can get into the rain. J 147 is doing that. It's just a little bit more potent than a creatinine. So I've used that it does work to like increase focus slightly. But what I would be interested to see is like over time for people that have some of these neurodegenerative diseases is what that helps do.

1:19:48 Because if we can increase the amount of oxygen, the about of ATP and everything that's getting to the brain is going to help more blood flow, obviously, which then will helpfully lower inflammation, Which then stems the tie of those. Um, there's another one called P 21 and P Is actually, if I'm quoting off of memory, right? A component of cerebral iso. So it's a peptide that is in the blend that they make when they're making some. And so it kind of like cerebralized and light, but it was one of those that no one really knows about and also to from a regulatory standpoint.

1:20:22 If we're saying like, okay, well, like Cerubilis and so powerful and maybe powerful people want that shut down. P 21 is going to kind of give you like 50 or 60% of the benefits of it without maybe drawing the attention of, you know, because through the license being porcine, there's like a lot of stuff that goes into quality control and then they can use that as like fodder for. like information to maybe stop it from getting out. But P21 is really cool. What I like about it is it helps modulate neurotransmitters in the brain, but also bring down inflammation.

1:20:54 So we don't have a ton of human data on it right now, But if you look at mouse models, they give it to mice with Alzheimer's disease, it brings down all of those inflammatory markers related to brain health and everything. So I'm excited about that actually. And I don't talk about this publicly too much. The way I found, I find out so much information just because I publish information. So. I get people that reach out to me. Um, what I finally found out was that I got tons of messages from parents with autistic children and they would use P 21 as a nasal spray.

1:21:26 They said it would like clear up like 80 to 90%, 90% of the symptoms of autism because it's helping a lot of cases. Autistic kids may have like dopamine. or serotonin dysregulation. And so it kind of affects their mood and it would improve a lot of their symptoms, help them with mental clarity, helped bring down to like more of like a stable kind emotional state. I was like, wow, that's pretty interesting. You start looking up data. It's like well, it was actually in the pipeline because it's an Alzheimer's peptide that has been used. So I've used that one personally and seen other people use it to great effect.

1:21:56 That will probably be one like years from now, obviously cerebral isin is amazing at doing what it does, especially when we look at like stroke and Alzheimer's disease. That's like more late stage to where you like actually will see like reversal of it. So I love cerebral ISM. The only issue. Can you get that now? Is it, it's tough. It's really tough, so there were actually compounding pharmacies. I believe this was like last summer, compound pharmancies and research companies were selling it. No, the research that we're selling.

1:22:28 Got letters from the FDA, which is kind of funny because these, these research. We're. Which is like, you know what the. FDA cares about going after, they didn't even care about it for that. And they went after cerebelliocin, which market wise is like pennies compared to the amount of GLPs. Cause you know, like a lot of people out there buying it. Um, but basically it was like, a cease and desist. So I know that happened. I knew a a compounding pharmacy. There are ways to get it. It's just one of those things from like a commercial supply standpoint until, because a lot of this rublescent that I know of comes from Russia or like

1:23:01 not Russia, but like the Eastern block to where it's like made around Russia because we plants there that. make it for hospitals there that it's used and hospitals that they have there. Um, and so a lot of it is coming in from overseas, but yeah, it, It's tougher to get, But if you can, um, absolutely amazing. And I would say, you know, for someone that is already like got good brain health, You might not want to use it maybe more than like one cycle a year or even one Cycle every two years. But for instance, like, with me, Like a of my mentors and former football coaches I have, I talk to them now and they're like in,

1:23:36 you know, in their sixties and I can see them having this cognitive decline because they had a lot of head trauma. And I was like, man, if I could get them some cerebral is and it would help, You know if it's like 20% progressed, cause I saw this with my grandmother, like twenty percent progress, Like stop it in the tracks there, instead of letting it get to like 80 or 90% to where it like might be too late. So look, I get it. So you're gonna ask a ton of questions that we could go on for hours. What I'd like to end with though, is we do a lot around longevity.

1:24:06 I mean, what is in your mind, the optimal longevity stack for somebody, let's say, our average age is 50 in our company, of our members that come in. And we have CEO types and hard chargers, and they're at the top of their game, they wanna stay at their top at game. But in you mind you know, the go-tos that, you should be part of everybody's stack. Yeah. Just quick hitting, I'll go through what I would say, a microdose of a GLP, whether that's semaglutide, trisapatite, or whatever comes in the future.

1:24:39 I think a microdose in those in right form or fashion, absolutely a component. And again, that irrespective of whether a person needs to lose weight. Obviously it would help if they do need to loose weight, The second one I would say is SSRT1, like we were talking about from my mitochondrial cell standpoint. Third would be a growth hormone peptide or a Growth Hormone Releasing Horman, Ceramorelin, Tessamerelin. I actually advise people to kind of like alternate through those and see which ones you like because everyone's going to have a personal preference and you can cycle them so you don't necessarily build up tolerance to one. Find out what you like.

1:25:09 Fourth one would be, it is technically a peptide would, be glutathione. I love glutethione, actually got a glutothione IV today, feel good. But I'll do that like two times a week, intramuscularly. And from like an immune health standpoint to an antioxidant defense standpoint, since I've been doing that, when I look at like some of those inflammation things on my blood work, cholesterol panel, inflammation markers and everything, liver health. I mean, it's crazy what glutathione can help do for that. Just one of those things is it literally is a pain in the butt because it stings if you're injecting it.

1:25:40 And obviously doing the IV is cumbersome too. Uh, and then the last thing, this is not a peptide. One thing that in a last like two years that I've seen completely transform and that the data on this, that's emerging as crazy is the SGLT2 inhibitors. Hmm. Mm. But anyway, what that does in principle is it blocks the reabsorption of glucose by the kidneys. So what, that means is that for people that are on the blood sugar roller coaster all day, which obviously creates all the metabolic havoc we were talking about,

1:26:13 it just, you end up peeing out the excess blood. So relative to the benefit you get from that, you do have to be careful with it because you can get like UTIs and things of that nature if you're using too much of them. But the. Benefit I've seen to people using those with GLPs, like a micro dose of a GLP plus an SGLT2 is insane. Like how good they work together. And I think there was a couple of recent meta-analyses published. Like there was a 50, when you have those two classes together.

1:26:43 So a GLP and an SGLT two 50% reduction in all cause mortality post heart attack when have both of those together? And so it's like, how would diabetic drugs end up improving heart health that much? It's because it is taking that metabolic burden off of the body. I don't know where that ends up going. If I had like a crystal ball, I would say like. that class of medications for longevity purposes will become one of the greatest things that we have ever. And then even in the short term, maybe that doesn't come true, but in a short-term like what it's doing for people's health that I've witnessed firsthand

1:27:18 from like reducing high blood pressure, reducing cholesterol for me, like taking in, the, in course of a year using those myself, my HDL went from around like 45 up into like the high sixties, low seventies. which independent of like anything else that I had been doing before. Um, and again, it's like, well, It's not directly doing that, but by like alleviating some of the metabolic burden that we all bear from living and having to eat and do stuff. It does cool. So I'm excited about those. We'll see where it goes. Obviously that's, not like what it prescribed for now, cause it is a diabetic drug, But there's more and more people in the longevity community that are

1:27:54 figuring that out and then using it to be a part of their protocol. So what I love about that is every one of those things you put in the stack, because this is for our physicians who are nervous about peptides, but everyone you just talked about is available. Yeah. And they're not like, we're talking about the... Not to go like some crazy website. We have to do research only. So I think this important because we are working on what is the longevity stack for physicians. Look, some physicians are very cutting edge and we have others that are more nervous.

1:28:25 This is kind of a gray area. But I love that. But look, I really appreciate this was great. Very educational. I learned a ton. Sure. Our listeners learn a lot as well. Uh, have learned and, um, and appreciate all your work and look forward to having you back again. Yeah. Thank you guys. It's been amazing here. Can I, uh, only been here half the day, but I cannot rave enough about how nice everyone has been. How about like, you know, given all the clinical stuff I did today from a testing standpoint, how much of like a spa environment.

1:28:55 It was once you're talking about like doing, you know, like CT scans and MRIs and stuff. That's usually not like very, um, welcoming warm environments, very sterile in a lot of cases. So I can't thank you guys enough. I'm excited. You know? Whatever we do in the future is going to be awesome. And the more I could help just get information about peptides to people, it's so powerful. The stuff I've seen in my life and the people I have coached and and if I, if you can help anyone by doing that, that's what I mean.