Ozempic Is Snake Venom Top 8 GLP-1 Myths Debunked

0:09 Hey everybody, my name is Hunter Williams. I hope you were doing amazing wherever you are out in the world. Today's video is going to be about how Ozempic is snake venom. Just kidding. today's Video is, uh, going talk about that a little bit, but what I'm actually going do is debunk the eight most common myths around GOP one peptide use. And, if there is any credence to these, how we can actually combat them and, end up, you know, not having any of the issues that are so widely reported in the media. So this kind of came to me this week. Someone sent a video to be of some doctor talking about how there's literally venom in GLB1 peptides that it's harvested from the venom of snakes.

0:48 And then all of these people are injecting themselves with it. What I wanted to do is just kind in my style and fashion, systematically break down if that's true and then along with some of the other myths out there, about GLP-1 peptides. And in celebration of the course that Jay and I have just launched, which is the ultimate GLp-one user's manual, how to use GLPs ones to maximize fat loss, maintain muscle, and improve longevity. I firmly believe that GL1-peptides are going to be the cornerstone of anti-aging and longevity medicine over the next 10 to 20 years.

1:22 So right now we're just using them for weight loss and diabetes, but I really believe they're the most powerful anti aging medicines that we have on the planet right Today, I'm just going to be reviewing eight of the most common myths that I found around GOP-1 peptide use. And then if there is anything to worry about there, how we can easily mitigate side effects and really use these to enhance not only our fat loss and our wellbeing, but our longevity as well. So before I do that, don't forget to check out the peptides cheat sheet. You can download that below. It'll sign you up for my email list.

1:53 I can say, stay connected with me and get updates and everything throughout the week. Also too, like I mentioned, I will put the link for the course in this video so you can check that out as well. It's very well put together, well thought out course on how to maximize GOP one use effectively. So without further ado, let's jump in. I'm going to talk about the eight most common GOPs one myths, and we're going have some fun today. All right, so today we're going to be talking about Ozempic is snake venom.

2:23 These are going be debunking the eight most common GLP-1 myths. So let's get into it. But before I do this, you guys gotta, I gotta lay the framework and guide work. What we are gonna do before we get in to these myths is just understand the history of GLp-one peptides. I've glossed over this in other videos, but today I want to just give a summary and overview of where they came from. Since this is probably going to be a big thing on the internet now about GLP ones being snake venom. Let's understand where it came. So around the 60s to the 80s, this was where the initial discoveries kind of came in.

2:55 The concept of incretins, which are gut-derived hormones that enhance insulin secretion, were first proposed, and this laid the groundwork for understanding GLP-1's role in glucose metabolism. And then in the 80s, researchers isolated and identified GLp-I,which is glucagon-like peptide-one, as a key increten hormone, And GL-P1 is produced in L cells of the small intestine in response to food intake. Leading into the 1990s, research showed that GOP1 stimulates insulin secretion in a glucose dependent manner, meaning it only works when blood glucose

3:28 levels are elevated, reducing the risk of hypoglycemia. So basically what that means is that when a blood sugar goes up, Excuse me. So basically, GOP-1 stimulates insulin secretion in a glucose dependent manner, meaning only works when blood glucose levels are elevated, which reduces the risk of hypoglycemia. GO-P1 was found to promote the survival and proliferation of pancreatic beta cells which produce insulin, and GOp- 1 was also discovered to slow gastric emptying and promote satiety, reducing food intake.

3:58 Now, this is where, sorry, I lost my spot on the screen a second ago, but this where we typically are going to derive benefit because GLP wants to make us feel fuller and more satiated. They do so by slowing gastric emptying. And I'm going go into what that means and there's a lot of like misunderstanding around that. So I might hopefully break that down in a better way for you to understand. But basically this led to the development of GLp-1 agonist The first one was called Xenotide and it was derived from Exendin-4,

4:28 which is a naturally occurring GLP-1 receptor found in the saliva of the Gila monster. And we'll get to this in a second. Um, and Xentatide became, uh, the first GOP1-receptor agonist approved by the FDA in 2005 for the treatment of type two diabetes, Which is what most people know them for. So, Uh, leading us into the 2000s, um, we had Lyric Lutide, was kind of a first mainstream one. Um, it was approved by the FDA in 2010, and, uh, It's a longer acting GLP one agonist, which allows for once daily dosing.

5:01 And it's also approved for weight management under the brand name sex sender in 2014. Um. Other ones such as Alba, Albal Glutide and Dulaglutides, Which is Trulicity. That's very common one. were developed and approved, offering different dosing schedules and delivery mechanisms. I believe Lira Glutide, or excuse me, Trulicity, not Lera Glutaide. Trullicity I believed is a once weekly use one. And in the 2010s, so we're moving on to the next decade, We had obviously the emergence and preponderance of semaglutide,

5:36 which is ozempic. So it was approved by the FDA in 2017. It is a once weekly GLP-1 agonist that has shown significant efficacy in lowering blood glucose and in doing so, providing weight loss. Remember that's always very important as it relates to weight-loss. And it's also approved for weight management as Wigoby in 2021. So just think ozempic, blood sugar, wagovi, weight management. They're really both the same thing. GOP1 agonists began to be combined with other diabetes medications for approved efficacy.

6:06 For example, Zultofi combines liraglutide with insulin deglutec. So you have other medications out there, but for all intents and purposes, that's kind of the story arc of GLP-1s and where they come from. So that leads us to today, the 2020s, obviously the most recent one and the one that I'm a big proponent and supporter of is Terzapatite or Monjaro. And the reason Terzaapatide works so well is it's a dual GLp and GIP, which is glucose dependent insulinotropic polypeptide receptor.

6:37 It was approved by the FDA in 2022. And it's shown impressive results with both glucose lowering and weight loss. So the GIP is kind of think of that as more fat burning than GLP-1, whereas GLp-I just suppresses appetite. G.I.P. works to help burn fat more efficiently. And then we have ongoing research. Obviously we would have red atrutide coming down the pipe that's still being tested for human trials. Researchers are exploring oral formulations and other non-injection delivery mechanisms. I actually think they do have a semaglutide.

7:08 Uh, oral tablet, I don't know how effective it is. I've never used it or talked to anyone that's used. But I did see that at a pharmacy in Mexico. So who knows? Maybe it's not even the real thing, but, um, the therapeutic potential of GOP one agonist is being investigated for other conditions beyond diabetes. Like I talked about, uh, including cardiovascular disease, neurodegenerative disease and non-alcoholic I'm not even sure exactly what that is. I just came across it in my research. In that context though, I've seen a lot of benefit for mental health as it relates to GLP-1s, cholesterol health, lipid markers,

7:44 all those things have improved. And my personal blood work since using them on and off and tons of clients that I coached in our communities and everything. So they're pretty much amazing, like I said. Now, let's get into, well, before I do that, lets get in to some results. So when we look at patient outcomes, GOP1 agonists have significantly improved glycemic control in patients with type two diabetes, reducing HbA1c levels. It's basically like a six month average of your fasting blood sugar, minimizing the risk of hypoglycemia.

8:16 The weight loss benefits of GOp1 Agonist have been substantial, providing an effective tool for managing obesity and related Comorbidities, like I talked about, there's a lot of evidence that supports cardiovascular benefits, whether that's from a lipid standpoint or also just overall heart health. And as far as adoption goes, GOP1 agonists become a mainstay in the treatment guidelines for type 2 diabetes and obesity management. And, uh, increasing coverage by insurance plans has made a lot more people able to access these, which I think is a good thing.

8:49 But as the story goes, most people can't have nice things. So let's look at the myths. Why can people not have things or why can' t people have Nice things? I, I would be more appropriate. grammatical structure. So, Ozempic is snake venom. Somebody sent me a video today of a doctor talking about how Ozmpic snake venom. I'll spare the names. You can probably find it on the internet, but let's look at it. Let's take a look the biological origin. GLP-1 is a naturally occurring hormone produced in the human body, specifically in intestines in response to food intake.

9:26 Okay, fair enough. So GOP1 medications are synthetically produced in laboratories using advanced biotechnological methods ensuring purity and safety. Take it from someone that understands the research chemical supply chain probably better than most because I have, you know, involvement in this with the nature of the work that I do. All the raw materials come from China and they are exported to the United States, as do every pharmaceutical drug, every supplement nearly, uh, or exported. The raw material is exported from.

9:57 Brought to United states manufactured here and then sold to people in the united States. Um, that's the case with pretty much everything you're going to take. So if you were going say that it was a big snake, then I'm well, let's look at the multivitamin that you are taking and all the other stuff you taking, but Hey, anyway. So this idea comes from the misunderstanding of Exendin-4. So the myth likely originated from Exended-Four, which I mentioned is a GLP-1 receptor agonist found in the saliva of the Gila monster which is the type of lizard. It's not even a snake, it's a lizard, but anyway, hey, I'll be honest. If there's anyone that's been more involved in exposing reptoids and talking about reptoys and stuff like this on this planet,

10:31 it's probably Jay Campbell or myself. So you can look into that on your own time if you want to. But if there is anyone against any sort of like reptoid involvement in my health, But this natural peptide inspired the development of synthetic versions, but is not used in human medications. So when it comes to nature, we can look at things in nature and then use them to inspire us to make things because of the mechanisms how they work. But that's a far cry from actually using snake venom.

11:02 in medication. And again, if there's anybody that's a conspiracy researcher analyst out there, it's me, I could have a whole YouTube channel talking about conspiracies. I actually thought about doing that. just talking about conspiracy stuff, because I could literally talk about it all day. I've read all the books, not all of the book because there's always more to learn, but you get the idea. So the nature of this peptide in this lizard inspired the development of synthetic versions. And then GLP-1 medications like Ozempic and Monjaro have been rigorously tested and approved by regulatory bodies such as the FDA and EMA during their

11:34 safety and efficacy for human use. Again, I'm no fan of FDA or EMS. I had my own YouTube channel deleted for talking about peptides. So if you don't think, you know, like, all these people that are out there saying stuff like this, why do they get millions of views on social media, and my channel got deleted last time with 2000 subscribers, I think it's like as of this video, 3400 subscribers or something like that. Again, use your critical thinking hat to take that in consideration. And so when we have molecular similarity, so while Xenobor share similarities with human GLP-1, the medications used in clinical practice are modified

12:10 to enhance their effectiveness and stability, making them distinct from any animal derived substances. So again, this is inspired by something that they found in a lizard. It is not lizard venom that are harvesting. And here's the other thing too. I think it's something like a hundred million people either in the United States or across the globe, probably just in United states alone have used GLp-one medication. If they are getting the medication from snake venom, where are the snake-venom farms? Don't you think they'd have to get a lot of snake venom, and that we'd probably have snake Venom Farms on every corner?

12:40 Again, I know that is what's the debate term. It's not hyperbole, but I can't think of the word right now. But don't you think that if that many people were using GLP-1s, that we would not have a shortage of snakes in this planet. So there's no shortage snakes out there literally and figuratively. Basically, when we look at synthesis, so modern GLp-2 medications are created using peptide synthesis technology, which involves assembling amino acids

13:13 in a specific sequence to mimic the naturally occurring GL p1 hormones. That's how they're made. Decades of research, like I talked about, and clinical trials have focused on understanding GLP-1's role in glucose metabolism and its therapeutic potential, separate from any connection to snake or lizard venom. You know, again, like, uh, I mentioned one of the, um, GLp-I agonists, they did say like oh, okay, this is working this way so that we could like maybe assemble a peptide in a chain that would benefit humans. Um, but again it's a far cry from using lizard venom.

13:44 And literally this doctor in this video is talking about like lizard venom getting stuck in people's veins when they take this. So leading endocrinologists and medical professionals endorse the use of GOP1. Again, I'm no supporter of the mainstream medical establishment, but I've just seen it in my own practice of what I do. They're very effective and safety profiles and side effects of GOP1 are well documented and monitored. through post-use surveillance with no connection to venom or other harmful substances.

14:15 And there's tons of different medical journals. Again, I'm not one to poo poo studies. I am not a fan of scientific studies because I don't think any of them are replicatable, but we understand where these are coming from and they're not coming snake venom. Moving on, yeah, I mean, that's a lot to unpack with the snake venom, but hey, do what I can to help people out. So thyroid tumors. I've actually had to have this brought up several times to myself.

14:46 And basically the origin of this myth came from rota models with these medications developed C cell tumors after being administered GOP1 medications leading to the boxed warning labels and public fear, obviously. That was another thing I heard in this video that you were guaranteed, this doctor said you are guaranteed to get thyroid cancer within 12 months. So let's look at this. So the initial studies that observed thyroid C cell tumors were conducted in rodents, not humans, which have a different thyroid physiology compared to humans. Rodent thyroid c cells are more sensitive to the GLP-1 receptor agonists than human c-cells.

15:18 Thus, the results observed in Rodents are not directly applicable to Humans. Also, when we look at dosing, we don't know, I couldn't find the dosage that was given, but I would imagine it was far, far more in terms of the relative body size of erodents to what humans are taking, that's just my own two cents. So extensive clinical trials and post-marketing surveillance have not shown a significant increase in thyroid tumors among humans taking GLP-1 medications. No causal relationship between GLPs and thyroid cancer has ever been established, even though you hear this all the time.

15:51 So despite the boxed warning regulatory agents like the FDA and EMA have approved GOP1 medications for use, the Boxed Warning advises against using GOp1 medication to individuals with a personal or family history of MTC or MEN2. And this precaution helps ensure that those at a higher risk are not exposed to potential, albeit unproven risk. So that's about thyroid cancer. Now, next one is ozempic face and ozepic butt. And this one's kind of funny to me because if you look in the Google search terms, it's like the most searched term around Ozempic is like Ozmpic face

16:27 or OzMPic butt. So let's look into this. Let's take it seriously. You know, let us not like throw it aside. Um, so rapid or significant weight loss from any cause can lead to changes in facial and body fat distribution. I know that myself, I'm having competed in bodybuilding competition in past and just dying down really hard. This is not something that is unique to Ozempic. It is a common effect when you lose weight, that you can have changes in your facial structure or your body distribution, i.e.

16:57 your butt. So, Ozmpic self does not cause localized fat loss in the face or buttocks. The term OzMPic face, or Ozmbic butt, incorrectly attributes the overall weight loss to specific body areas when it's really just the weight that's coming off. So this would be like seeing a dead animal on the side of the road and seeing the vultures that are there eating the animal and saying the Vulturs killed the animals. To someone that doesn't know about cars, they would say like, Oh yeah, that makes sense. The vulture's are eating it. So they wouldn't have killed it, right? Well, of course not.

17:27 The animal's on the side of the road dead because it was hit by a car. If you lose weight, you are going to have a gaunter faced because you lost weight. if you had a bigger butt and you loss weight you're going have smaller butt because your lost body fat. So, and potentially muscle too, which we're gonna get into. Weight loss achieved with Ozempic is generally systemic, so it affects the entire body rather than targeting specific areas, as does any weight loss. The Ozmpic just enhances your ability to, or Ozimpic or Manjar enhances you ability lose your weight So appearance of facial or buttock changes reflects

17:59 overall body fat reduction. Changes in facial, orbutic appearance due to weight loss vary greatly among individuals and depend on your genetics or baseline weight and other factors. And then also too, when it comes to this, most people mess up what I'm going to talk about, but maintaining a healthy diet, engaging in regular exercise and proper skincare can help mitigate the appearance or sagging skin or other changes associated with weight-loss. If you want to live on this planet, being fat will be a hindrance to that.

18:30 Even if this were true, which is not, it's just when fat people lose weight, they will have a more gaunt appearance and their butt will smaller. If that was true what is going to kill you faster? Would you rather be fat And then not like, it's just to make sense to me. So it was like these medications are helping people lose weight and, uh, you know, we need to appreciate them as such. Okay. Submit number four. I kind of grouped in a lot here.

19:00 Um, but what I did is I took all of the side effects off of label for church appetite. So what I'm gonna do is run through those and then I am going to provide a rebuttal to all those side effects because I believe if these are side-effects that are caused by the medication, it's really a side effect of a person not managing their lifestyle, their diet, they're exercising, training properly. So brief overview, let's view the side affects on the label of these medications. One, nausea, or these were the common side affect. There's common effects, there's less common effect and there are rare but serious side of effects.

19:34 Let's look at common set effects nausea, diarrhea, decreased appetite, vomiting, constipation and digestion. Okay. Less common side effects. Abdominal pain, indigestion, fatigue, injection site reactions, dizziness, belching, GERD or gastroesophageal reflux disease and flatulence. Pretty much the same first is the first one, just different words to say the rarer but serious side effects, so much more rare. Pancreatitis, hypoglycemia, acute kidney injury, small virus and disease, severe gastrointestinal disease hypersensitivity reactions,

20:07 thyroid C cell tumors, and increased heart rate. Okay, fair enough. So let's walk through each one of these and talk about them. Nausea. Why do people get nausea when they use GOP ones? One, because they are used to eating a ton of food. And if they continue to eat that amount of gastric emptying, slowing down is going to cause you to have nauseous. So how do you combat that? You eat smaller, more frequent meals to avoid overwhelming the stomach, especially on your eating days. I recommend you have fasting days and eating when you're using GOPs.

20:37 You also are going want to drink water and avoid fatty, spicy or greasy foods that can exacerbate nauseam, which you probably should do anyway. Okay, moving on, we have diarrhea. So why do people get diarrhea? Well, I think these medications are more or less, they kind of bring to surface a lot of the issues going on with people. Basically a poor state of health. And then you bring in a GOP one and then introduce, you know, uh, very poor lifestyle habits to it.

21:09 It's going to bring to issue a lot of these services. So basically to combat the diarrhea, You want to include fiber rich foods, help regulate bowel movements, obviously stay hydrated with electrolytes and avoid dehydration and incorporate probiotics. I would add in metformin to do so. Decreased appetite. Obviously that is a side effect because you want it to be a site effect. So to basically offset the decreased appetite, you'd want to eat a high protein diet. You want focus on eating nutrient-induced foods to ensure adequate nutrient intake despite the reduced appetite and maintain a regular eating schedule

21:45 like I talk about in all the books and everything that we have and all of the courses that So we have vomiting. So how do we combat vomiting? So eat slowly, chew food. You should always be chewing your food, you shouldn't be like wolfing down your foods. Consider consuming ginger or ginger tea, which can obviously help with nausea and vomiting, we can do other things too like glutamine, lemon juice, apple cider vinegar, all those things should help. And avoid overeating and large meals, what can trigger vomiting so a lot of people will do this. They'll like use Ozempic or Manjaro and their appetite will be way down.

22:16 And then they'll just have like these huge gorge meals who like, well, I haven't been eating that much. Then they do it and there's not enough room in their stomach because they haven' been. Eating as much for those foods. So they have obviously negative side effects in the form of vomiting. Constipation. So on one side we have diarrhea and then on the other we had constipations. This, in my experience, comes from a lack of magnesium. Obviously the gastric emptying slowing is going to mean you have smaller and less frequent bowel movements. But again, with everything, you want to increase your fiber intake.

22:51 And I will say, bare minimum, everyone should be taking at least 500 milligrams of Magnesium Citrate per day. Then from there, if you still have constibation, just titrate up until you no longer have I believe for everyone, there is a threshold at which you will reach a magnesium citrate to which, you no longer have constipation. Try me on that one. It will work, I promise. And then there's obviously too, people are just not exercising when they're taking these medications. So regular physical activity. I've always had this idea and thesis around like moving the body helps with gastric motility because you're moving your stomach around,

23:23 so it helps like move food through the system. Now that could be completely crackpot, but I think the exercise helps the digestion. Go figure. Um, and then there's indigestion. So avoid lying down immediately after eating, always try to walk for 10 minutes after your meals. Uh, again, eat smaller, more frequent meals throughout the day, you know, on your eating days, I recommend five to six meals and limit intake of foods and beverages to cause indignation, such as caffeine, caffeine. Alcohol and spicy foods going to get to alcohol on second. Okay, so let's go into some of these larger side effects. So we have pancreatitis.

23:57 First, I'm not a doctor, but how do we avoid this? So be vigilant for symptoms such as severe abdominal pain and seek medical attention, obviously diet. And then I think the big problem with this is people are drinking alcohol and You know, ironically, this helps people not want to consume alcohol, but people will still do it anyway for social pressure or whatever. Yeah, when you drink alcohol with this, the GLP ones and alcohol do not mix. Again, GLPs ones will expose you for what you are.

24:28 And if you're a flaming dumpster fire, they're going to bring to the surface. So if have pancreas problems, most likely it's from the alcohol consumption, not the GLP one. Next we have hypoglycemia. so again, just eating regular balanced meals to maintain blood sugar and not taking too huge of portions with your meals and regularly monitor blood sugars. That's very easy to do with a blood glucose monitor. The next one is acute kidney injury. So this a lot of times comes from hydration and inset use, which is non-steroidal anti-inflammatory drugs like ibuprofen.

25:02 First thing, you have to drink electrolytes when you're using GLP-1s. Typically you are going to deplete minerals, I think, in my experience, a little bit faster and a more than you would without a GOP-1. So definitely you should always use electrolytes, but in the case of GOp- 1, you definitely want that. You're typically going to be fasting more and eating less. I would say electrolyte are key for that too. But then another thing too that I didn't really think about because I stay away from these is the use of NSAIDs.

25:32 And I think if there are any sort of things that come up with people's kidneys, it's probably in conjunction with other medications like NSAIDS that they would be using. Um, gallbladder disease. I don't really know too much about this, but this is like, you know, obviously one of the big ones. So, uh, just incorporate healthy facts like avocados, eggs, and olive oil, um, a diet high in fiber can help reduce the risk of gallstone formation. And then also regular exercise. Um. We mentioned the thyroid CTEL, CTL tumor. Again, with this it's really just monitor yourself.

26:02 You know? Like if you have a family history, it just monitored. But I really think you. Have nothing to worry about. And then the heart rate, um, this is a weird one. I haven't heard this as much, but it was on the label. So I wanted to include it. Um, obviously manager, you know, monitor your heart. And, and then you should always be exercising. so it kills me how many people will use a GOP one and they don't exercise and don' diet whatsoever. It's just kind of mind blowing, that you're paying to use this medication to achieve a result. You would think you would want to funnel everything in, But I understand that human behavior.

26:32 Just exercise in stress management is going to really help with any sort of like increased heart Now, myth number five, you have to take it in the light. Hunter, I would love to use this, but I don't want to become dependent on it. So let's look at this in practice instead of theory. Research indicates that many patients successfully taper off GLB-1 medications after achieving their health goals such as significant weight loss or improved glycemic control. For instance, healthcare providers often recommend that patients gradually discontinue these medications once they reach their desired outcomes,

27:03 emphasizing the importance of monitoring and lifestyle adjustment during the period. So, there's some real-world adherence data we have here. A retrospective cohort study from the UK found that while adhering to GLP-1 medications can be challenging, meaning people can't take a once a week shot, A significant number of patients discontinue these treatments within 12 to 24 months, often after achieving meaningful weight loss or improved health metrics. So most, the majority of, patients come off of these within twelve to twenty four months once they get where they want to go.

27:33 And then healthcare professionals, including endocrinologists, advise patients to use GOP-1 as part of a broader treatment plan that includes diet and lifestyle modification. Obviously, you can take all the turzapetide in the world. You take 30 milligrams of turazapatide a week. If you don't do your cardio, if you Don't exercise, don' resistance train. if You don''t drink water, If You Don'''t eat healthy, only so much is gonna help you. So clinical guidance and patient experience to show that many individuals can successfully reduce or stop GLP-1 therapy once they get to where they wanna go. And factors contributing to this include follow-up visits, comprehensive lifestyle support, and adherence to healthy diet.

28:09 Again, this is just human error and human fallacy is that people need support and they need to stick to a plan. The GLp-one is simply a tool that helps you create the environment, to have a healthy diet, have healthy lifestyle, train properly, eat properly and all those things. Moving on, myth number six. This is a big one, GLP-1's cause stomach paralysis. Let's look at what stomach perlalysis is. Basically, GOP1 medications can slow gastric emptying as part of their mechanism to enhance satiety and control blood glucose levels.

28:46 So their effect is different from gastroparesis, which is a chronic condition where the stomach cannot empty in a normal manner. So the temporary slowing is controlled and reversible, unlike the pathological delay in gastro paresis. Let's look at clinical evidence of this, again, not the biggest fan of obviously, but let's just look what happens. Clinical trials and post-marketing studies of GOP1 medications, including SEMA Glutide and Leroglutides have not shown significant increase in incidence of gastoparesia among users. Many patients experience gastrointestinal side effects like nausea or delayed gastric imping initially, which often subside with continued use as the body

29:24 adapts to the medication. So again, this is a transient effect, not indicative of permanent stomach paralysis. This is very similar to metformin. As the microbiome is remodeling itself through these agents, People will take metformin the first 14 days they're having, you know, nausea, stomach upset, all these problems, diarrhea, whatever. It's because their gut is so toxic. I think it's really this to their guts. So toxic that the body is having trouble moving all the stuff out, which leads, to this quote unquote gastric paresis or stomach paralysis.

29:59 As of now, you know, this is always subject to change. There is no substantial evidence leaking GOP one to permanent damage of the stomach muscle or nerves, which are involved in true gastroparesis. So a lot of times people are experiencing a transient effect as their microbiome remodels to the medication. Um, and study has shown that any slowing of gastric emptying induced by GOPs is temporary and reversible on upon discontinuation of. And, uh, most medical experts agree, like again, I'm not a fan of expert consensus, but there you go after years of using.

30:29 Now, this is one that someone sent me again today and I was like, well, let's address it. So somebody said that GOP1s cause fat cell hyperplasia, which is basically the enlargement of fat cells. Now let us look at this. GOPs work by enhancing insulin secretion. They slow gastric emptying and promote satiety. Their effects are centered on regulating blood glucose and reducing food intake, not on increasing the number of that cells or hyper plasia. So clinical evidence on weight loss. Numerous clinical trials have demonstrated that GLP-1 medications like semaglutide and their glutide lead to significant weight-loss in patients by reducing

31:04 appetite and calorie intake rather than increasing fat cell numbers. So the focus is on decreasing body fat through energy balance rather that altering fat-cell biology. If there are studies, it's hard to find. I couldn't find anything. And so when we look at GLP ones, you know, temporary versus permanent change. They may cause temporary gastrointestinal side effects to the body. Just, they do not equate to permanent changes like fat. So hyperplasia, um, and the side-effects are manageable and typically subsided with continued use, whereas hyperpleasure would play a lasting alteration

31:36 in that tissue structure. Again, just wanted to throw that out there because that was a popular video. Some. Myth number eight is going to be GLB ones cause muscle loss. Obviously this is one of the larger claims about GOP, the ones that they will make you lose muscle. Right? Let's dig deeper into this. So what, again, is the mechanism of action? So GOP1 medications primarily target insulin secretion and appetite regulation aiding in blood glucose control and weight management without directly affecting muscle mass. Studies have shown that GOp1 medication do not cause significant muscle loss.

32:06 Again, I'm not one for studies, but that's just what we've seen. Participants experience fat loss with preservation of lean body mass. So combining GOP1 treatment, again, this is the key, combining GLP one treatment with regular physical activity and a balanced diet, particularly resistance training helps maintain and build muscle mass during weight loss. Again, when you lose weight, some of that will be muscle because you are losing weight off the body. Most people do not do resistance. Training when they were losing. Wait, I have seen time and time again. Clients that I've had in my own life.

32:36 I'm seeing this in. My girlfriend's life, if I had seen this and my clients, When you are resistance training, you can actually increase muscle while losing fat while taking a GOP-1. I can probably make another video about that, but GO-P1 medications improve overall metabolic health, including better glucose control, reduced inflammation, and improved cardio health which contribute to maintaining muscle integrity and function, not losing it. And then obviously we have not seen this at least like in a substantial way. Now, are people losing muscle when they're taking these?

33:06 Of course, but those people are not doing resistance training. So they don't have a comprehensive plan to support resistance. They don' use growth hormone peptides, they use hormone optimization, and they can help support muscle growth. If you take a GOP-1 and do not resistance train, you're going to lose muscle. But if you do it properly, then you will not lose muscles. All of that to say after debunking and evaluating some of those myths, what are the best practices? So I always say keep getting low.

33:37 So stay at the lowest recommended dose for as long as possible. Now, depending on your situation, I can't speak to everyone here. Uh, you should be able to get really good results with that lowest dose. And then once you go up in dose, uh, Try to keep the lowest dose possible. I realize like some people have to use these again for extended periods of time. Um, but you never want to just keep upping the dose and uppeding the does for no reason. Uh, I say fast 19 to 22 hours per day, three to four times a week to get the best results. Now that is something that not a lot of people are talking about around these.

34:09 If you do that using these medications, you will blow the doors off results, um, that anyone else will get. I also recommend looking at hormone optimization. So we have obviously like the reproductive hormones that I'm a big proponent of. You can look up other videos on my channel, but I'll also highly recommend for muscle preservation to use human growth hormone or a growth hormonal agonist peptide to preserve muscle during fasting and the caloric deficit that we're going to be in. Uh, on those fasting days, like I recommended do two fasted cardio sessions, one in the morning and then one right before you break your fast.

34:43 This is probably the biggest mistake and also like the thing that you could do to, um, enhance the results you're going to get with GOP ones is to train with weights at least three days per week. If you can do that, I promise you, uh, all of the muscle loss nonsense is going. Um, basically be something that. You don't have to deal with it. I know I didn't put the myth of muscle laws on here. But basically, GOP1s don't cause muscle loss. People not resistance training cause muscles loss, consume adequate protein. Again, when we talk about muscle losses, it's because people are not eating enough protein to eat at least one gram of protein per pound of lean body mass.

35:20 Take magnesium citrate and electrolytes. So take magnesium sitrate before bed and electro supplements daily. Obviously, I recommend atleast 500 milligrams of magnesium. Um, and this is also to where people mess up. They do not take breaks. So I recommend, you know, for every eight to 12 weeks of use, take four to eight weeks to maintain sensitivity to GOP one so that your body, do you not have to keep increasing those effects. And then, uh, obviously this should go without saying, but avoid alcohol consumption. Like I said, GO P ones and alcohols. alcohol do not mix.

35:51 So stay away from those. And that is it for the slides. That's going to be the eight most common myths of GLP1U. Hopefully that made a strong case in the other direction because so many influencers on the internet now are talking about how dangerous and how bad all of these So this was just my best attempt at an argument on the other side, because I think it's really important that we, you know, kind of evaluate these. And before we throw the baby out with the bath water, really look at what's going on here.

36:22 Kind of like the analogy I talked about with, the, dead animal on this side of the road is really the vulture that killed that animal. Or is it that it was hit by a car? And I, think a lot of times people have tons and tons of health problems, and then they blame the animals. a peptide that helped them lose weight for those health problems. So again, those are going to come back to diet, training, lifestyle, exercise, all those things that everyone should be doing anyway, whether or not you have a GOP-1 peptides. Again, like I said, I think these are gonna be the hallmark of anti-aging and longevity medicine, probably over the next 10 to 20, maybe 30 or 40 years,

36:53 depending on what else comes down the pipe. But Um, thank you guys so much. Uh, and, you know, as always leave comments below. If you feel like I left something out or could have dressed a better, definitely let me know. I definitely, even though I can't respond to all the comments now, cause there's so many, I'll definitely take you guy's feedback into consideration and I use it to help drive, uh, content on the channel. Cause again, this is just about serving you, guys, making sure this content is useful and has a place in the world and makes a difference in people's lives. So thank guys. And I will talk to you in next one. Peace.