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Reader Mailbag · Episode 1

2026-04-20 · 54:09 · 6 min read

Taylor and I sat down to tackle some of the bigger questions you've been sending in. These aren't the rapid-fire Q&A types we do on Saturday coffee talks. These are the ones that need real context. Let's get into it.

A 33-Year-Old Woman With Low Hormones Across the Board

The question came from a 33-year-old female dealing with low mood, no libido, no motivation, social anxiety, poor sleep, and irregular periods. She's on Armour Thyroid and some peptides. She wanted to know which hormone to start first.

Taylor's first pick is progesterone. It helps the nervous system, the social anxiety, and regulates the menstrual cycle.

For dosing, treat progesterone by symptom relief. You're not chasing a number on a lab. Most premenopausal women start between 100 and 200 mg, days 14 through 28 of the cycle. Start at 100 mg for 90 days, see how you feel, adjust from there.

The old advice that women shouldn't take progesterone every day is outdated. There's plenty of newer research showing daily use can work great, especially for women dealing with anxiety.

How much does birth control wreck this picture? About 100%. Birth control uses progestins, which are synthetic. They lock onto your hormone receptors and block your body's natural production of estrogen, testosterone, and progesterone. They keep women stuck in a PMS-like state.

Roughly 80 to 90% of irregular periods get solved by addressing progesterone properly.

Then Add Testosterone

Progesterone alone might solve 40 to 50% of this woman's symptoms. The next layer is testosterone.

Unpopular opinion. There are probably more women in their 20s and 30s who are candidates for testosterone than men in the same age range. Microplastics, food quality, generational birth control exposure, stress, adrenal fatigue. Women are getting hammered from every direction.

For a woman in this case, I prefer injectable testosterone over cream. Here's why. With injections you can introduce a very low dose, even 1 mg per shot, and let the body acclimate over two to three weeks. Cream has a more aggressive spike in DHT, which can drive masculinization.

Injections also convert to estradiol better than creams do, which matters for libido. A typical starting protocol would be 5 to 10 mg of injectable testosterone per week, split into two or three shots, into the delts. Most women do fine with a 28-gauge half-inch needle.

If cream is the only option, rotate the application sites. Constantly putting it on the labia thickens that skin and desensitizes the area, which works against the libido goal.

On progesterone dosing, someone in our group asked if there's data showing benefits at 300 mg or higher. I went looking and found eight or nine studies showing benefits at or above 300 mg nightly for bone density and hot flashes. Some women do well at 50 mg. Some need 600. It's very individual.

Can Peptides Treat Ovarian Cysts Without Surgery?

Depends on severity. If you've got a softball-sized cyst or it's an emergency, surgery is the right call.

For smaller cysts, especially tied to PCOS, yes, peptides can help. My stack would be metformin plus a GLP, probably tirzepatide. Maybe a little Jardiance rotated in.

PCOS is really insulin resistance manifesting as a hormonal imbalance. There's a push right now to rename it Reproductive Metabolic Syndrome, which is more accurate. Every woman I've known with PCOS had lifestyle issues that needed to change. High stress, alcohol, processed food, no exercise.

A lot of women on GLPs end up getting pregnant because the cysts resolve once the metabolic dysfunction does.

The honest question is how often surgery gets pushed when three months of tirzepatide, metformin, and lifestyle changes would have done it. I'm not blaming doctors. They see the same five issues all day and most patients won't change their lifestyle. But the option should be on the table.

Can Kisspeptin Help Libido and Muscle Gain on TRT?

For muscle gain, no. There are way better peptides for that.

For libido, yes, there's something there. Kisspeptin-10 has a short half-life and needs twice-daily dosing. Kisspeptin-54 is harder to find but lasts longer.

There's brain imaging data showing increased excitability in reward regions when subjects were shown erotic images on kisspeptin versus off it. We just started using it as part of our fertility journey. Not a replacement for HRT, but a nice cherry on top.

Taylor had a client living in a country without HRT access who hadn't had a cycle in years. Kisspeptin brought it back.

Anti-Aging Benefits of Melanotan Beyond Tanning

Melanotan-1 has more going for it than just pigmentation.

Cognitive benefits are real. If you live somewhere with low winter sunlight, it can give you a similar dopamine hit to actually being in the sun. It also enhances how your body responds to whatever sun you do get. Thirty minutes of light might feel like four hours of benefit.

Vision can sharpen too. Immune benefits are well documented across the melanocortin receptor peptides, including KPV, TB-500, and PT-141.

Melanotan-2 leans heavily toward tanning. Melanotan-1 lets you get most of the ancillary benefits without as much pigmentation change. It hasn't affected my tattoos.

My Pre-Workout Stack

Right now I'm experimenting with DADA. Injectable DADA is great. Transdermal DADA also works well. Oral works fine too.

When I'm doing injectable pre-workout, my go-tos are 500 mg of L-carnitine and a blend with phosphocreatine, ATP, AMP, and choline. Sometimes I throw in injectable amino acids.

I've stepped away from injecting pre-workouts as much heading into bathing suit season because of potential lumps in the glutes.

For drinkable stuff, I like Unmatched (Chris Gethin's brand) and Perfect Aminos. Element electrolytes are clean. I avoid most commercial pre-workouts because the artificial sweeteners tear up my stomach.

When I used to make my own, the recipe was 3 g beta-alanine, 5 g AAKG, 3 g citrulline malate, 3 g taurine, 5 to 10 g essential amino acids, some L-carnitine, plus creatine HCL or kre-alkalyn capsules.

Detoxing Beyond Glutathione

You can't avoid environmental toxins entirely. You live in the world.

Wash your produce. Taylor soaks everything in water, vinegar, and baking soda for about 10 minutes, then rinses, spins the lettuce, and air-dries berries before they go in the fridge. Wet produce molds.

Beyond that, here's what we use.

Sauna is huge for detox. Glutathione weekly. NAC. Zeolite as a binder. Activated charcoal. Spirulina and chlorella, but go slow on chlorella because it can put you into detox shock.

KPV orally is great for gut and inflammatory load.

We also do ionic foot baths (the Ion Cleanse type). Some people call them a scam. I don't agree. Week to week you can see different things come out depending on what you ate or were exposed to.

Living near farms, golf courses, or in heavy pollen zones means you're breathing measurable pesticide residue. Detox should be ongoing, not occasional.

Teens and Peptides

This is hypothetical. I'm not telling anyone to put their teen on peptides. But let's talk through it.

For a teen athlete with an injury, BPC-157 and TB-500 are completely appropriate in my view. The evidence we have suggests they're safe and effective.

For acne, KPV, thymosin alpha-1, and LL-37 would be far better than what teens usually get prescribed. I took doxycycline as a teenager for acne. I just learned this week that the same antibiotic is used to treat STIs. It gave me ulcers, gut issues, candida problems for years. Compare that to a peptide like KPV.

Topical ivermectin (yes, the horse paste version) also works well for acne.

For obese teens, GLPs are being studied in that population. If a teen is genuinely doing the work on diet and exercise and still struggling, a GLP could have a place. If they're crushing Doritos at 2 am playing video games, fix that first.

ADHD is the one I'd push back on. A lot of what gets labeled ADHD is just kids with energy who weren't built to sit at a desk for eight hours.

The hypocrisy is real. We hand 13-year-old girls hormonal birth control without blinking, but we panic at the idea of a teen using KPV for acne or BPC for a torn shoulder.

Also, parents, stand over your teens and make them do their skincare routine at night. It matters.

My take

The big theme across all of these questions is the same. The tools work, but context matters more than the tool. A 33-year-old woman with crashed hormones needs progesterone and testosterone, not a peptide stack. A teen with acne probably needs better skincare and maybe a topical peptide before an antibiotic. A woman with PCOS needs metformin, a GLP, and lifestyle changes before surgery.

Keep sending the longer questions. The more detail you give, the more useful the answer. We'll keep doing these mailbag episodes as long as you keep supporting them.

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Full transcript click any paragraph to jump video

The end. Hey everybody, this is Hunter Williams. I hope you're doing amazing wherever you are at in the world today. And today we're actually not doing a live stream together, even though we will continue to do the live streams together.

But what I wanted to is just something a little bit newer and do kind of like a reader mailbag edition because we do lots of Q and A videos. Obviously we have our private group. We do our Saturday morning coffee talks, which again we'll continue But a lot of those Q and A's are rapid fire. And so we're trying to get through as many questions as possible because there's a lotta viewers and we are getting asked a lots of things. So sometimes we need like 10 or 15 minutes on each of these questions. I think they're really good questions to answer. But there is always the trade off like, okay, how do we make sure we get to all the questions but then also answer them in the right way.

What we wanna do today is I've taken some of the question that I get from you guys that you submit to me which you can always do down in description. video topic request form that I have a document that collects all those questions, which is very helpful from you guys. But what I want to do today is take some of these that, I think, are going to be longer type questions. And we'll probably go for like an hour or so, but we're going take these longer-type questions and really break them down. Some of them are female-focused, but get both Taylor and I's perspective on them.

And I think this will be fun. It's not just the typical Q&A. There'll be kind of a deep dive Q and A that's a little bit more situational, because thanks to you guys, I get some really amazing questions. Sometimes it's just a quick question that you can't answer in like a 60-second sound bite. Then sometimes, too, it like, a whole life situation, which I appreciate and think is good. But it would be beyond the scope of just answering that in a like 60 second sound clip. So that's what we're going to do today. We'll see how it does, but I think this could be really beneficial.

And obviously Taylor and I are already having these conversations anyway, in a lot of cases, whether it's just for people in our group, people that we worked with and whatnot. How's that sound? Sounds good. Ready to go? Ready. All right. The first one, we've got some ones more specific to women that I wanted to bring Taylor into. And the first is this is very similar, I guess that, that would say to someone in a situation like us, or at least our age age group, ironically, a lot of people that follow us are older than us.

Which I appreciate, but it just seems like people in their thirties are not as into the peptides as people. Although I think that's changing. I think it's changing, but I also think our age group is the age where I just feel like most people don't take longevity and their health and wellness really serious until they're closer into their 40s. Because that's when you really start feeling the decline of everything happening. And I people in our age group are having kids or they have young kids, or there in the process of having, kids are currently pregnant or,

you know, sometimes self care like is pushed off on the back burner because they were just trying to survive the life changes of being parents. Yeah. Well, here's a question. And I think it's, we'll probably go deep on this. As a 33 year old female with low hormones across the board, should I start one hormone with HRT at a time? And if so, which one first? The main issues I'm having are low mood, no libido, No motivation, social anxiety, poor sleep, irregular periods.

I currently am on armor thyroid and some peptides. Wow. If you had a 33 year old, that is the 33-year-old avatar of an American woman right there. Would you agree? Yeah, definitely. Yeah. What would be your first building block in a situation like this? Because obviously we've worked with a lot of people, even though like most of the people that we interact with are a little bit older, we have helped a long people like us. So I would say the, I would say the first building block would be the progesterone.

And to start with that, that's going to be most beneficial to help with the social anxiety. It's gonna help the nervous system. Its going help regulating the menstrual cycle as well too. Then I'd go in and I'll add in Well, first, sorry, not to interrupt them, I'm not trying to interupt Taylor. Dosing wise, cause a lot of women get confused on the dosing for progesterone. Would you have like a recommended starting point that's not going to be too much, but then they could kind of like. Yeah, so with progesterone, and this is where a lot of people don't realize is that you really want to treat progeterones by symptom relief,

meaning that your not worried so much about what your number range is when you get your blood work done, you're really trying to just get relieved with the symptoms. Did I say that correctly? Symptom, your really wanting more symptom really. Get relief from the symptoms. Yes. Yeah. Not symptoms from. The relief. Do you have symptoms? From the relief? Um, so most cases, most women are going to start off with, um, anywhere since you are premenopausal, I would say anywhere between a hundred to 200 milligrams.

Most women. Are going. To do days 14 through 28 of the menstrual cycle. I think that can work great. Now, studies and everything is changing with progesterone and I would say for many years they said like you shouldn't take pro gesterones every day as a woman because it can have negative impacts on your cycle and on fertility. That is not the case anymore. There's plenty of studies out there, published articles and studies about that.

I think for a woman that is in their 30s, I thing progesterone every day can be extremely beneficial, especially if you're a women who has anxiety and dealing with a lot of anxiety problems. And this is one coming from working with clients and coming personal experience with that as well. So I think that, you know, You can benefit from using it every day. I Think starting off with day 14 through 28 is a great way to start off though. And I would say start that for at least 90 days, see how you feel with That.

and then you can always make the adjustments and I Would do a lower dose, start with a hundred milligrams. Then if you need to work your way up to 200, it's always better to Start lower and work Your way Yeah, I think progesterone would be the one thing that I thank you, especially for women in their 20s and 30s. It solves so many issues. How much do you think of that is made worse by birth control? Meaning the anxiety, the no motivation.

Oh, it's 100% the birth control. I mean, birth controls is going to go in because, you know, there's a difference between progesterones and progestins. Progestins are synthetic hormones that they put in birth-control. And what happens is, is that those progettions actually lock onto your hormone cells. It locks onto you estrogen, and locks on to your testosterone, your progesterone, actually blocks those cells from being able to produce the body's natural hormone production. And then it also, because it's blocking that, it is keeping a woman locked in her literal phase of her menstrual cycle, which is what we know as the PMS phase.

So a lot of times you will actually get worse side effects of that, plus you're blocking your body's natural hormone production, that is what is leading to cancers. That's what's going to lead with her issues. It's also going leave with, you know, cognitive function issues, like you are going be doing your more damaging in the long term by doing that. The irregular periods part, I mean, how much of that is solvable by... I just feel like that's one thing.

You have all these women that have the irregular period and I feel the progesterone component is just never even addressed in mainstream medicine when in reality that could fix a lot. I think it's like 80, 90% of irregular So it was actually interesting, because when I was personally on synthetic progestins with birth control, I actually had irregular periods. That actually caused me to have irregular period. So progessorone is actually going to help regulate your periods and get your period more on track.

Now, 33-year-old woman, let's say we address the progeserone. Maybe that solves 50%, maybe not. I think this case is going solve, like I would say, I would say 40%. Well, then the next question would be testosterone. The next answer would for them to start testosterone, yes. Interestingly enough, I think there's probably more women in their 20s and 30s. This would unpopular opinion. I mean, there are more woman in there 20 and thirties that are candidate for testosterone than men.

Yeah. Well also you've got to remember too, like as women, you have to while your mother feed us is in like the uterus, like everything that that mother has endured in her life, that's being passed into the baby. So like if a mother was on birth control previous, before getting pregnant, I mean, That's going to be an effect on the Baby while it's in the room growing. Then you add in you know, just how much the environment has changed and how many microplastics are in the enviroment now.

Food source is so much different even like when we were kids versus like kids now and just the quality of the food, that's going to make a difference. It's gonna make difference on both genders, males and females, but it's gong to be a bigger impact I think on the women. Plus, you know, we have a lot more, there's other hormones that need to be taken care of here. And then you add in the fact that you have like all these synthetic hormones also going on now too. Most women are put on birth control by the age of 13. Yeah.

Which no one bats an eye out. Then you want to give a 27 year old testosterone because they don't have any testosterone. Everyone loses their mind because it's a hormone. Meanwhile, we're genetically engineering or epigenetically engineering women to block their hormones when they're 13, which is crazy. I think the testosterone component, if you look at women too, a lot of stress, lot anxiety, all compounds, and then a of women's testosterone, not a part of it comes from their adrenals and they have adrenal fatigue.

And so they are not getting anything from that. Then their ovaries, you know, who knows how much is coming there from endocrine dysfunction. And so there's just, it's an uphill battle. And when I see those symptoms, low mood, no libido, motivation, social anxiety, or sleep irregular periods, progesterone and testosterone would have so much of that. Now in terms of, cause the question was, which one first would you do both of those concurrently to start? I would do both of those together. Those are two that like, if you wanted to start separately, totally can.

And I always say start with a progesterone and then add testosterone. But those are too, that you can start together and most good HRT therapy doctors are going to prescribe them together Yeah. Well, and this is where it gets into then it's like, well, they get the testosterone and the progesterone from the doctor, but oh, wait, now it is a cream. And then they respond differently to the cream, which is then a whole different conversation. My preference would be the injections.

This would not seem like the case, But when you're doing the injection, as a woman, you can actually introduce a lower amount of testosterone at a slower pace with injections than you came to cream because of the nature of, the way that the creams are metabolized by the body, you actually have a more aggressive spike in dihydrotestosterone, which is what causes the mass colonization. You also have more of a punch from the cream. It's harder for the, body to acclimate to the punch, whereas the injection you can start with a really low dose, even as low as like one milligram per injection.

and the body becomes acclimated to that over two to three weeks without having too much of a rapid change, whereas the cream does kind of cause that. And so that's why we're bigger fans, especially in the case of this situation right here, of the injections, because it's going to kind ease that person into it, rather than having them have the, the creme and have aggressive. Now, does that mean that some women won't do well on the creams? Of course not. Some women will do, well, on that creams. It's just pound for pound. I would say the objections would probably be, the best place to start. And I would say when you go to your doctor, request that.

You know, some people might not be comfortable injecting or they're scared of injectings. This person said they were on peptides. So it sounds like they'd be okay with that if you inject a peptide, you can definitely inject testosterone with the 28 gauge half inch needle, depending on the preparation that's in. But most women do completely fine with and you just do it into your delts. Don't even have to worry about your glutes. A lot of women don't want the injection scar tissue lumps around the glute. they'll usually do pretty well for most women but I would say that's a short answer is 10 milligrams injectable testosterone or five to ten milligrams

of injectible testosterone per week broken up into two to three shots 100 milligrams per gesturone probably going to end up taking 200 milligrams progesterone You know, it's interesting is someone in our group asked us about 300 milligrams of progesterone. They're like, is there any studies to show that at 300 mg or higher pro gesterones, there's more benefits? And actually I was like well, actually this is a fun rabbit hole to go down. And I go looking and there was at least eight or nine studies that I found that showed that there is benefit at or above 300 milligrams nightly of progesterone for women for bone density, for helping with hot flashes, which is not the use case here, but I do think it's one of those things.

It's going to be different for everyone. Some people need 50, 100, some people 200, 300, something we need 600, But I think that it is one thing that there are benefits as you go higher for a lot of women with the projesterones. But you get those thing, the testosterone, projesterone, peptides are going work better. The thyroid is good to beyond, it will not solve everything. Also, I wanted to touch base going back to injectable versus cream. One of the other things that's going to be beneficial for this case in particular is the injectible testosterone I feel like is going be better because

it's also going help convert testosterone into estrogen even though I would not suggests a woman at this age going on estradiol, depending on where she's at in her fertility journey, and she might not need it yet. With cream, you don't convert testosterone cream into estridiol. That conversion rate is a lot lower, whereas then when you have an injection, your actually are gonna be able to convert, testosterone into estrodial better. So in that case study, plus she saying that she has low libido, she's going to feel a huge difference in her libido with injectable testosterone versus

a cream because of that conversion happening. And that's the other thing is too, is that again, there's nothing wrong with cream. Like if that is your only option, it's still great. I would just highly recommend you really rotating like where you're placing your cream, How well are you absorbing it? Because a lot of women will constantly just put their cream on the labia area. That's actually going to cause a thin stick, like the thin to actually get thicker. And the thicker that skin gets onto that area, you're going lose sensitization to that.

area and if libido is already an issue and then you become desensitized to. that, area you are not going be able to even enjoy intimacy at that point. Yeah. Yeah, which again is just an opinion, but yeah, that's not, I'm not saying every case is like that, Well, I think that's very beneficial for a woman that is kind of out there and also don't feel bad too. I would say the women in their twenties or thirties that I've just seen in the world that we are, and they don' really know where to turn.

And they actually think hormone therapy is for them. In the woman's world, we think of just post-menopause hormone, when in reality it can be. That's why I said, even I, think there's more women that are a candidate for testosterone in there twenties and thirtees than probably Yeah. Yeah, I mean, there's a lot of candidates in their twenties and thirties as men, but I think we see a lots more of this. Whereas a man in his twenties, and 30s can do a loss to optimize naturally. That wouldn't be, you know, always going to be a proponent of testosterone. But yeah, it's much more beneficial to a woman in that case.

It can help with fertility, use testosterone therapy and IVF to help conception. in the lead up to pregnancy, not during the pregnancy but to help with IVF. Staying in a vein of women, I kind of self-selected these, can peptides help treat ovarian cysts without surgery? I'd say yes, depending on the severity of the cyst.

I'm not going to sit here and say that if you have a massive cyst, like a softball, would that be your best option? I just wish. Well, in some cases it could be an emergency. that would be, if there's an emergency case, then it needs to be surgically taken out. It needs be surgery taken now. But if you're somebody in the sense that like has like smaller ovarian cysts, something that I experienced in past with,

I think peptides can definitely be beneficial. I mean, you control, that you can, definitely help with that. Would be like, not a peptide, but metformin would, be one. Um, and then are the GLPs. Yeah. I think metformin plus a GLP, even if it's just a low dose, if even it was just semaglutide or zaptide, retitrotide would be king for fat loss. Probably trisaptides. Trisapetide is my choice of a glp to use in the case of like specifically for ovarian cysts, PCOS.

They're usually in same category. A fun fact was actually reading this morning. They're actually, there's a, being a big push right now, I think amongst a lot of practitioners on a specific group to change the name of PCOS to actually reproductive metabolic syndrome, which is really what it is. It's high testosterone levels. PCOS is insulin resistance. Yeah it is and that it manifests in the sense for that and I think that's why so many people if you have a GLP it ends up helping them get pregnant because

it gets rid of the cyst because again it's a metabolic thing that is happening but I Think metformin plus a glp plus even a little bit of Jardience here and there could be very beneficial for That and i think if You approach those things and then Don't even get me started on the hormone piece because yes, like you said, they call it high testosterone. I think it's an imbalance of androgens to estrogenes that are caused by the metabolic dysfunction that ends up looking on paper. It's like, oh man, this woman, she just has high testosterone. Is that really what's going on?

She just got bit by a testosterone bug. Now she has testosterone, it is an imbalanced because of the nature of metabolic disfunction. Every woman that I have interacted with and has dealt with PCOS, even prior to being in working in the health realm, all had lifestyle issues that need to be changed. High stress levels, tons of alcohol intake, poor dieting, doesn't exercise. I mean...

Chick-fil-A. fillet. Inside joke. Yes. So, I mean, a lot of it is lifestyle-based and diet makes a huge difference. Even if they don't drink, the amount of processed foods and sugar that's also recurring in that diet is... Well, let me ask you this because I don t know enough about the women's side of things, especially in the cohort. Just because we had a family member recently How many do you, okay, I've fully acknowledged there may be cases where a doctor needs to do surgery on a

cyst because that could be potentially life threatening, right? That's granted. How often do think the surgery is pushed in lieu of adjusting lifestyle? Meaning that like, if you said, Okay, this woman has a sys, it's non life threat. You had cysts, they were very painful, but you didn't have surgery. No, they wanted me to do surgery on my fibroids and get like basically the essentially like it's like a birdings and like. Right. Meaning that how many times, and this is across the board of medical, there's lots of great doctors we love, but this was just kind of the nature of beast.

Are they pushing surgery in lieu of those lifestyle modifications to where it's like you go have a surgery that costs 20 grand to have the cyst removed. You have to do the trauma of surgery when all it would have taken is three months on turzapotide, metformin, some Jardians. That was the last time I ever went to a OBGYN. Yeah. That, that long ago. I don't think that it's not like they're bad intended. It's just, imagine if you saw five women with PCOS per day.

And honestly, how many of them are going to change our lifestyle too? I think also too, like, and this is where I do have to have more compassion for medical providers is that they're seeing case after case, after a case. And I remember when I did, when, I was a stylist and, um, one of my clients was, was doctor and she worked in family practice. I her saying, you know, this was like when semi-glutide had came out and it was like starting to be talked about a little bit.

And I remember her just being like, I don't want to, give it to anybody. But like after a while, she's like I just get tired of like hearing the same thing over and over again. So I'm just like here, take it, go. I think of a lot of doctors after awhile, like imagine having to deal with the five topics, dealing with that eight times a day. Probably more, depending on. So I do have more compassion.

watching the show, the pit on TV made me have enough compact, like man to have to deal with this stuff. I know that's a TV show. It's dramatized. Yeah. But we have friends that have told us that that is very much what like the E which that the ER, I can't imagine the stress of doing that on daily basis. Like emergency, but again, depending on the field of medicine, just seeing the same thing. We both learned that we could never be in that kind of, we had been like oncology, not dealing with like, Emergency medicine.

Yeah, we couldn't be in an emergency. No, I don't do like I had to get the dog. I gave one of our dogs a shot of LL 37 and I was just like, like having to give him a shop was like. Well, let's say for the. Dog, it hurt you a lot less. It hurt me more. He didn't hurt him. he could have cared less doing it, but injections. They have a very rough hide. And he cried more when I. Was just trying to look at his ear.

Good question though. I think it's one of those things. It's like a very large cohort of women, underserved, very, a lot of, let's just say lack of education in that area. Last part of the women's health. This will probably be a quicker one. If a woman is already on TRT, can KissPeptin further help with libido and muscle gain or is that overkill? I'll actually say we just started Kiss Peptine just to have some cherry on top with our fertility journey. Probably is not going to do much relative to what we're already doing. Yeah. I will say this, I wanted to select this because a lot of people throw kisspeptin in the wayside because it's not a replacement for HRT.

I would never say it is a replace for H.R.T I had a client use it though who did not have access because of the country that she lived in to hormone replacement therapy and she hadn't had cycle in several years and used Kisspepton and got her cycle back. Well, in that case, I think it's obviously, it is better than nothing. What I would say is that long-term, for the next however long or live, hopefully longer, but just say 50 plus years, you can't use kisspeptin for 50 years.

But I can use testosterone for fifty years but to the point, the reason I say that is because people are like, oh, kiss peptine, not testosterone, throw it to wayside, is just a poorer version of testosterone. It's not that. There's actually a lot of data. You have two forms of kids peptin, kids peptin-10, and kids Peptin 54. It's hard to find kids. Pepton 54, it's got a longer half-life. Kids Pepsin 10 has short half life, meaning that you would probably need to administer it twice a day to really get the effects. But. there is data around kiss peptide actually increasing people's libido.

And so they show me, I think there's a study, it's men and women. They showed them erotic images and they got more excited. So they monitored their brain when they were being shown the erotica images, they get more exited. Yeah. How about that job? Do you think that I go through and like picking the pictures out that they're going to show them? Oh, pick that one. I want that job. That'd be funny. they have the brain data to show that whatever region, I forget what region it is in the brains associated with like reward,

pleasure and everything, is more excitable on kids' peptin than off of kids pepton. And so I think in a lot of cases for this person's purpose, muscle gain, eh, no, don't think so. But I mean, there's way better peptides to help with muscle, kids, pepton, that's for sure. but if someone's on TRT, especially a woman, i think the kids peptin can help drive some little extra libido. Yeah. Maybe that's more so for men. I don't know how much it would be for women, but I do think there is a use case. And there's no harm in it. It's relatively affordable at the worst case you're like, yeah, maybe it didn't do anything.

But I have noticed that myself just a little bit more excitability. Yeah. But again, the female libido is going to be very complex. Testosterone is not always the cure for female labido, although it can help a lot. It's not really secure. So to go back to the adrenal component too, I think that can have lots to do with it as well. Here's an interesting question. What are the anti-aging benefits of melanotan beyond tanning?

Does it preserve hair pigmentation? As someone that is one of the premier purveyors of The Ancillary Benefits of Melanotan to the world, what would you say? We can talk about anti-aging benefits. Do you think there's benefits beyond tanning for Melana? I think it has a lot of cognitive benefits for the brain. Absolutely. Tell more. I mean, I can't really give you the scientific backing on it. But the cognitive function that you get.

People don't want the science backing. They want to know what it does for them. What it is that when you're using melanotana, it gives you that same cognitive benefit that get from going outside and being in the sun and getting that sun exposure and creating that cognitive feeling just from using that peptide. So you still get that. I think it enhances my receptivity to the Sun. Yeah. Meaning the sunlight feels better when I have... It does, but if you're somebody who lives in an area where you don't get exposed to sunlight for a certain period of time of year,

it can actually give you the same dopamine, cognitive benefit of being in the sun mentally too though. Yeah, I wonder if it's because basically it enhancing the melanin receptors in the skin. And say like you live in like Buffalo, New York and it is January, you might get like 30 minutes of sunlight per week. If you go in to the sun, it able to absorb that good 30-minutes of sun light a lot more effectively than you would if you didn't have it. I mean, we still got the sunlight, but it like, maybe it turned the 30 minute into more like four hours of some light to then confirm the benefits.

And it enhances your vision too. So like that's also like gonna help too, it's not necessarily going to like, I don't like to say it, like I think of it more so it was like being able to see like HD or what's higher than, what is higher, 40 now, was higher. K, UHD 4K, 8K. All the TVs at Best Buy. I like these super expensive TVs. It's funny because like 80% of the TV's when you go to Best buy, they kind of all look the same. And then it's like, whoa, you see that one TV.

Really clear. Yeah. They have like the nature. So it looks even cooler. That's why am I looking at nature inside of a TV, inside a place called Bestbuy that has tons of Wi-Fi and email. You love going to Best Buy though. I do, that's what I'm saying. But then you realize I give it fries, I couldn't imagine working there, how much it would fry you. To the benefits, there's a lot of immune benefits to Melanotan-1. A lot of the MCR peptides, accordion receptor peptide, KPV, 10-1, PT-144, there is a lot immune benefits to those, which is really cool.

Definitely some brain health benefits, I would say. I mean, it's not going to be as strong as like a cognitive. No, it's not. Some brain health benefits. Hair pigmentation. Would that mean, I guess, like if you have dark hair, if your hair keeps you from going gray? I don't know necessarily like hair pigments. It can shift the pigment of your hairs. So if there's somebody who has like lighter hair it can actually like darken. Make sure they're darker. I think it makes my hair lighter.

But I get kind of lighter... No hang on, now I'm getting like Does it make it lighter? I can't, now I'm can remember. I feel like it makes my hair lighter in the summertime, but I am also outside in sun and it gets. Yeah, it does make your hair later. But does that mean it will make someone. Or is it DHK that makes. DH K makes her hair darker. Okay. Sure. So it'll make her lighter, But it doesn't affect my tattoos. Cause I know a lot of people are worried about that. And it has not affected my tattoo.

Several years ago. Yeah. But lots of benefits. I think you could say Melania Tan 2 would be much more focused on the tanning. Melana Tan 1, you can really take and not necessarily get overwhelmed by the tannin. You'll probably have a little bit of pigmentation change, but you kind of get all those benefits without it. but I do think it's a great peptide. Here's the juicy one. What is your pre-workout stack and what do you think about commercial pre workouts? Have you ever taken C4?

That's kind of like the age-old like bro C-4 or pre-workout C four, as in like explosive C 4. Like Hydroxycut? I wonder if they're from the same, I think it's Cellucor is the company that makes C for, yeah. I feel like they may have been affiliated with Hydroc. It's like, the one you would see a lot at like Walmart and GNC and Costco. Yeah. I think pre-workouts, I mean, definitely go through my phases right now.

Like I'm just like not. You could drink bum pre workout. Not sponsored. Shout out to bum come sponsors. Um, all right. Now I am not a fan of injecting. a ton of pre-workout into my glutes, just cause I know like we're going to be traveling. I'm going be, it's becoming like bathing suit season. So I don't like doing it as much because I will get lumps. But right now I would say I've been liking experimenting with Dada.

That's been one of my favorites, but if I were to do a pre workout injection, I think like injectable Dado is good. Injectable O-Carnitine, injectible Choline, Injectable choline is probably one of my favorites. And when I say I'm not doing it, this has been a two week thing I haven't been injecting. I think, yeah, what else? My stack would be, this is kind of what I'll rotate back and forth.

I've got some injectable L-carnitine, typically 500 milligrams of injectible L carnitene. And then I will do a little blend that has phosphocreatine ATP, AMP, and choline in it. Sometimes I would throw in some injected amino acids. It's in a blend. Research companies, so some lysine. Those are really good. So those are my favorite. And then Dada is great too. We've used a transdermal version of DADA.

That's been, I've been liking that, the trans dermal data. I actually did trans dermals and I took the oral data yesterday. Yeah. The oral works pretty good too I like injecting the DADA, but the Transderma does work pretty well. Dado just kind of makes you keep going further. I honestly have not been using, admittedly, too many pre-workout mixes, like a scoop powder mix that you would mix in water. I used to be the biggest, drink a pre workout, drive in my car, or drink it on the way there.

Actually, you remember when we first met and we were making our own workout powders? That was probably the best one. And I kind of want to go back to trying that again and see if I can drink it. Because my issues with the drinkable pre-workouts and a lot of the essential amino acids My issues with a lot of those is that they,

it's the sugar substituted in the flavor enhancers. I cannot drink a lotta them. Like I just, one, I'm just somebody like, obviously I am drinking an energy drink, but what I like about this, is it not like overly powerful. And if it has like a, like I don't know. You don' do well with beta-alanine. No, that gives you the tingles. Yeah. I love that. I like the tingles. It's not that it's my stomach. Every time I drink them, I just feel like I have like intergestion and I can burp them up.

I do like Perfect Aminos. They're vanilla amino acids. I like that one the best even though like it's vanilla flavor and like using that as like in my water while I'm working out is not like ideal. But because like the flavoring is very light, it is overly like sugary tasting, I don't get like the upset stomach from it. It's like when stuff like has like that overpowering like sweetener, like flavored enhancement to it, and I like it which I dont really drink.

I just like to take a place of like plain water words and you'll put more like electrolytes and flavored enhancers in your stuff. Like I can't do that. like I feel like just tears my stomach up. And it makes me thirstier, like it just like, I feel like that's never, it's not refreshing. I like my, my intro workout really sweet. I'll do some amino acids, some essential amino acid with some electrolytes. Like when I'm working out, I was just thinking about the funny, like the group, how you get so is so grotesque to you.

Or to me, love like something sweet while I am training, something about, even if it's just like sipping on it, while training like when i'm like sweating and stuff. Because it's something like Powerade and Gatorade brings you back to like football, whereas in like... I actually didn't really drink powerade in Gaterade while I was playing football because it would hurt my stomach. See, that's where I get a hurt stomach is if there's like a lot of sugar or high fructose corn syrup in those cases. That would have hurt me. I mean, I wasn't playing, so I didn' like it. Then Troy Palamalo used to always say that Gatterade was a scam.

So I remember Troy So he, he doesn't drink it, but no, it would actually, all the Steelers fans will literally come after you. You don't know. Sorry. But anyway, I didn't like it when I was playing football because when you're running around the sugar for whatever reason, like I always just would get like crampy in my stomach feeling. However, intro workout when i'm weight training, i like the sweet feeling because it makes me drink versus just regular water.

If I sip regular, water I won't drink. Like it was plain water, but if I have that like sweet feeling, it like makes me want to drink more than just having the regular water intra workout. But I'll just do some essential amino acids. I like the unmatched brand from Chris Gethin. They're really good. And then I will throw it. The perfect amino is good too. some electrolytes. Usually just kind of like whatever, like Electroshred from Unmatched is pretty good.

Whatever I have. I like the Elementi electrolyts. Those are pretty too. Like the salty nature of those. The Strawberry Cooler from unmatched, that one's the better. That one I can handle more. Yeah, so that's my my pre-workout injection. Yeah. I don't really do Drink pre workouts that much anymore. Although I used to make ours and what I would do is I just buy like the bulk supplements off of Amazon and I Would do five grams of Beta alanine,

which is a lot compared to like what you would get in your typical mix. Five grams of, or no, three grams beta alanines, five grams arginine alpha ketoglutarate, AAKG. Three grams, of what was the other one that I would have that's kind of like, Three grams of citrulline malate. Citruline Malate's a really good vasodilator. And then I would do some creatine. I do take creatinine HDL, but I just take the capsules. Creatine or kregatine is another good form of creatines.

Is there taurine in it? Or is that the nighttime form? I'd put tauring in as well. Yeah. So three grams taurenine, five to 10 grams essential amino acids all blended together. I think that was it. Oh, I put some L-carnitine in there, so I like to put, you know, L carnitene powder in. You do that. And honestly, for me, could drink those without even flavoring them. The beta alanine has like a little bit of sweetness. So the sour and the sweet of the betaalanine, if you just have the raw powder, it is pretty, It's an acquired taste.

It was pretty nasty, but you were to make your own. I used to that because it's hard with the supplement. We used the drops. What drops? For the flavor drops we used. Stir. Yeah. You have the stir, S-T-U-R. They're pretty good. There's Stevia. Do you feel like you have a stevia distaste? I wonder if that's why you get so sick, but some people have, well, a lot of people think that stevea tastes like cilantro.

Oh, I love cilantro- No, no, wait. People that don't like cilantro tastes like soap to them. Yes, that's cilantro. Yeah, but I think with stevia, there's a lot of people that have this visceral nasty reaction to steve. I don' like it as much. It's not good for you, Sucral is better. I mean, it probably tastes better. To me it tastes. I have sucralose, like yeah, whatever.

It's like, that's what takes us down. If I'm at a coffee bar and I having to choose what to sweeten my coffee with and like sugar is not there, I would do probably, the Splenda over the Stevia. Yeah. And I was looking on the bum to see, do you like these? I think it's monk fruit. Sucralose, see? That's what I like. Oh well, we're going down. The sucralase is going to take us down Speaking of which, on to the next question.

Beyond weekly glutathione, what else can we do to protect our bodies from environmental toxins, especially pesticides on fruits and vegetables? Why don't you first talk about what you do, to our fruits, and vegetable? I guess probably how do you clean the fruits? Just soak them. I soak it in water, vinegar and baking soda. Soak everything in that and let everything soak for like a good like 10 minutes. And then rinse them, put everything through like, a lettuce spinner.

And then I let all the, all, the berries have to let air dry. That's the key to is like letting all everything that you wash, letting it air drive before you put it into the fridge. Cause that's when like it can create mold. If you'd put in there wet. I think you have the option to have like a small like sustainable, like garden like that obviously would be the best. It's not realistic for everybody though. That way at least you're being able to source it yourself and you know what's going into it.

I think as far as like to be able true that I like KPV would be beneficial to use. That's where like oral peptides can come into good play as well too. Also too like sauna, sauna makes a big difference. Sauna is huge for detoxifying. One of those things like you're, we're going to get exposed to it. You can't help the fact that we live in the world that you do. Unless you live under, like in your bubble, you are going get to expose to when you go out. Yeah. I think one thing we probably, I know we haven't really talked about or talked enough is Quicksilver Scientific has the,

It's like a binder or something. We have activated charcoal, zeolite. Zeolight is a huge one that is kind of a binder that will help pull toxins out. And then I think it has, I don't know, maybe it had like inacetylcysteine, spirulina and chlorella are really good for pulling some of those things out Be careful with chrorellia when you first start it. Yeah. I would say spirullina. It can put you in like, a detox shock if you overuse it, and I did that. Yeah, but, uh, glutathione, inocetylcysteine, zeolite, activated charcoal, spirulina.

One thing I used to do, I don't like, if I was to eat like a really bad meal, you just take some activated, charcoal and spirullina powder, and you talk about nasty, But it will like help get the nastiness out. So I think if you do that a couple of times a week, that probably helps. Obviously the sauna is huge, getting stuff out, sauna. Foot baths, we do a foot bath. Yeah. Can you can talk the footbaths? Yeah, the foot detox baths. I don't like what's the technical like? The name of the brand I think is like Ion Cleanze maybe. But it basically, cause a lot of our toxins are like around like what area it kind of just like runs like an electrical current that like helps dry out

some of those toxins. It is interesting like week to week you can kind see different things that will pop out that you probably like, Oh yeah, I did eat a lotta bread this week. Some people will say like there is a scam, but it's not cause there's definitely times. Peptides are definitely a scam and they're Chinese. And they have endotoxins. You should never use them. Their endo toxins are from China. Yeah, exactly.

Anyway, the foot baths are really good. I think they're great. Question, do you have more toxins in your peptides or just from breathing air in the United States? Breathing air? I'm going to say breathing in United states. We live in Carolina. Most of the areas in The United, well, we choke on pollen. You actually, there's a measurable roundup in that air and a lot of, it's meaning you're just breathing it in air. Especially like if, sorry. Especially if you live near farms.

That's the thing too, it's like living in the country is amazing and being free and on the land and having that freedom, yes, that's great, but if are living on a farm, or your case, growing up basically in tobacco fields and farming, like that also Those pesticides are going into your water system. Like you're sharing the same soil and water source with that. Now the guy that lived across the street from us growing up, he was a farmer and had farmed for his whole life there.

The area was like a tobacco farming. And this has been years ago now, but he died of stomach cancer. And I always just wondered how much of that was caused by being around all the stuff that gets sprayed on that, the water table you're drinking. Well, water that is in an aquifer that's directly under where they're spraying pesticides year after year. Golf courses. Yeah, golf courses too. The big one. meaning that regardless of how healthy you are, you should be detoxing all the time.

I think there's like many things that you can do. Obviously like there was like huge crazy protocols you could do, but just like on a regular basis, glutathione, sauna, some of those binders that we talked about and just be like moving that stuff out. And yeah, like you'll be exposed from it time to time, it's still a good practice. All right, last question today, because we've been rambling for a while. What are your thoughts on teens using peptides for acne, acne scars, even for weight loss, for obesity, ADHD, and maybe even BPC for sports injuries? Is any of this appropriate?

Are teens absolutely not a candidate for peptide? My teens will be taking them. Well, I would say if they were going to use anything, there were probably certain ones like I will not gravitate towards first. Yes. Like the GH peptides, can a teen use those? Yeah, think they would be fine with them, but that would not be like, wouldn't go there first, But for instance, like if you had a, a team athlete that had an injury, and I think PPC and TB 500 are completely appropriate.

I don't see what evidence we have to suggest that that will be appropriate, Now, I'm not telling you to use teens. Actually, the purpose of this video, you should never use peptides in a teen. Hypothetically speaking, though, for the purposes of doing fantasy role play, there's absolutely that you could use it, especially for an injury like that. I think for something like acne, Man, I wish I would have as a teenager had some, some KPV and some thymus and alpha one and LL 37 for acne. So I think they're absolutely can be used.

You know, ADHD is a weird one. I wonder sometimes how much of ADHD teens and kids just have a lot of energy. And so if we say that they don't sit at a desk for eight hours a day, compliant. Or they just learn different. or they learn differently, or if they don't do that compliantly that they all of a sudden have ADD. Yes, I realize in some cases that some kids are going to be very ADT, and I understand that. And there can be behavioral issues that stem as a result of that, but I do think peptides could be appropriate to help manage or improve the environment

in which it's causing some of those things. I think GLPs, they're being studied in teens right now. If I had an obese teen and they were doing everything they could to lose weight, meaning that they weren't like shoving Doritos and Mountain Dew down their mouth at 2am in the morning playing video games. I would fix that first, but I do think the GLPs could come in and help there. But acne, yeah, I think all the normal peptides that we would say that would use for things like that in adults, it are appropriate for teams. Usually people are very smart about how you do it.

One is like, okay, are they obese? Well, if they're not exercising and they are not changing their lifestyle and are eating crappy, then don't give them a GLP. There should be kind of the same thing for adults ironically. So I think it's one of those things like it, it it a contextual thing, but I don't think there has to be like a hard pass rule of like, no, until that teen turns 18, he can never have BPC or KPV or whatever. Well, here's the thing too, is that like with teens, especially with the acne issue is at, they will jump to put a teen on a antibiotic that can do- Or Accutane.

AccuTane that could do horrible damage. Like, you know, like one of the antibiotics to treat STIs is the same antibiotic they use for acne. You know that? I didn't. So like think about that. how powerful that is. I took antibiotics for acne as a teenager and it ruined doxycycline. It ruined me and I found out actually this week. They use that to treat STIs.

Yeah. Well, I mean, it makes sense. It's an antibiotic, but I found out this week you can actually get ulcers in your stomach from taking it, which explained probably why I had a lot of gut issues after that, that were for several years, you know, Candida, and then it can go into your brain and you go crazy. And then you have ADD cause you've got Candid in brain. Cause you took an antibiotics for your acne, You know that was probably hormonal and probably just part of being a teenager. But it's crazy to think that you couldn't give a teen that. Yeah, But then we're going to sit here and say like BPC, Well, if teens can get to bring it back together to close the loop,

teens and get hormonal birth control. Why can't they get KPV? Yeah. You know, like, yeah. Or LL 37 for their acne, or if they tear their shoulder in a sporting event. Yeah, BPC. Also with the acne like topical ivermectin horse pace can actually work really great for acne. And I know it sounds a bit much and this is where like I got it. I'm not a parent yet. We don't have kids yet, but this is where like honestly staying on top of your teens with their like nighttime and morning skincare routine.

Like, might suck but you might have to stand there and watch them every night do their night nightly skincare routine until they just automatically do it because that makes a huge difference especially dealing with acne and you know as much as It's interesting because my mom really drilled that into us growing up. And I remember being a teenager and going to girlfriends' houses and stuff, and my friends would go to bed with their makeup on.

I was like, oh no. Like, I had my whole bag ready to go with my skincare routine. But I remembered one of my friend's mom, it was probably like 14 at the time. It was maybe eighth or ninth grade. My friend mom was just like... You have a very sensitive skincare routine and her being like, this is what you need to be doing with your skincare. Yeah. And peptides could be a part of that, even if they're not injected ones. So you have to make a judgment call as a parent. We can't tell you how to parent, officially don't use teens or don' use peptide routines.

But I will say I have personally witnessed that and it's always gone pretty well. Anyway, all right, well, that is the reader mailbag for this week. Thank you guys for sending those questions. As a reminder, make sure you send those question over so we can do great things like this. And hey, if you wanna write a thousand word essay in your question, by all means do so because I think in this we'll be more able to kind of break down like we did today. I'll make your Hunter reads that one.

The more info, yeah, I will read it. Well, do summarize these because some of these were like paragraph, But it's helpful the more information guys like if you need help with something and you're submitting one of these questions the More information the better. Yeah, because we don't know your history Yeah. And you ask things like, I don't know, like okay, what peptide isn't working? You know if you're 72 and you are using RETA and it's not working anymore. It's like maybe you have no testosterone in your body. That's why the Reta doesn't work. So anyway, thank you guys so much.

As always in closing, we are blessed, privileged and honored to be able to bring you these messages. Without you, We don' exist. support us. We appreciate that more than you know. And as long as you guys keep supporting us, we will keep bringing these to you. So let's know what you think of this format, if it was helpful. I know sometimes in the comments, people were like, like get on with it, stop the BS. But I think there's a lot of context and nuance around some of these conversations that it takes a while to like flesh out in a longer form podcast like this.

Anyway, in closing, We love you, guys. See you in next one.