Revitalize Your Heart: Powerful Peptides for Heart Health

0:09 Hey everybody. This is Hunter Williams. I hope you were doing amazing wherever you are out in the world. Today's video is going to be the peptide stack for heart health. So it is no secret and has been no secrets for a long time that heart disease and atherosclerosis and heart conditions have been the number one killer of not just people in United States, but people across the word. Obviously this is a huge problem. Again, people talk about it, it's kind of one of those things. It just isn't assumed disease that I think a lot of people assume they're going have when they get older.

0:39 and that does not have to be the case. So in light of a lot of recent personal messages and comments and everything I've gotten recently, I decided to finally make a heart health peptide stack. I made ones about high cholesterol and high blood pressure, but today I just want to do an overall heart-health one. Whether you are someone that is concerned about heart disease or you've had that quote unquote run in your family, or you just want to be preemptive and live the longest, live, the strongest, and do the best you can to optimize your health as you are aging. This peptide stack will be for you.

1:10 So I'm going to walk through all of my favorite peptides. Some are peptids and some are more just, you know, ancillary medications that I would throw in to help someone that is on the path to having severe heart disease or maybe even already be there could use. I'm not going to say this is going cure everything, but it definitely will be helpful. So again, none of this medical advice. This is just me talking and spit balling and coming up with ideas that I happen to put into very well articulated videos and research slides. That's what we're going talk about today. Before I jump into the slides, one thing that seems to have been working that a lot of people like lately is me posting the link to my slides.

1:46 So you can actually download those as a PDF. If this video gets 500 likes, what I will do is pin a comment at the top, or you could go to a link and just download this as PDF, you won't even have to opt in with your email address or anything like that. So once this video gets 500 likes, I'll make sure to do that. I just do one because it helps, obviously, push it out there, but also two, it gives you guys a reference guide and a framework with the video so that you can take it home and install it on your own life so you could actually use this to get results in your life instead of just watching it and,

2:19 uh, you know, mentally and visually look at it, but also like implement in your own life. So, don't forget, check out the peptide cheat sheet. Um, the email, sign up for the e-mail list down below and sign it up to that. And then also to, if you want to join a community of amazing, beautiful people that love to talk about this stuff on a daily and weekly basis, checkout fully optimized health. Uh, we do live AMAs inside there. every week with the group and also have an amazing forum where you can not only talk with me, Jay Campbell, but some of the other amazing biohackers and

2:50 people we have in there that have been in their four years and contribute amazing wealth of information to the space. So without further ado, I'm going to share my screen. And today we're going learn about the peptide stack for heart health. All right. This is the peptide stack for heart health and I am Hunter Williams. So let is, let us jump on into it. Sorry about that. For some reason, there's this thing that my slides do where it like blurs them. But anyway, so what is heart disease? So heart is this is basically the leading cause of death worldwide.

3:20 which is responsible for nearly 18 million deaths annually, and that's crazy. In the United States, heart disease accounts for approximately one in every four deaths, which has affected over 30 million adults at some point in time. Common types of heart disease include coronary artery disease, heart failure, arrhythmias and valvular heart. Um, and obviously the major risk factors, like I've talked about before, high blood pressure, High cholesterol, smoking, diabetes, obesity, poor diet, And obviously lack of physical activity.

3:52 And when we look at the economic burden of Heart disease it's huge with costs expected to reach over $1 trillion per year by 2035 in the U S alone. So there is no. slowing down of heart disease in the United States. And again, it's kind of one of those things. It's like, we know obesity. We know high blood pressure and all those. But why do those end up becoming a problem? Because it leads to heart diseases and heart attacks that people have that causes them pain. So I did a little thing where I think in terms of like disease, they have this thing called the four horsemen.

4:23 Well, I do a four Horseman of Heart Disease. What I Did is just basically, obviously there's many more causes and areas of disease that you would look at contributing to heart disease. But I kind of looked at these four as basically like the biggest issues. So the first one is inflammation. Chronic inflammation is a major driver of heart seas and it contributes to the development of atherosclerosis, plaque instability, and heart tissue damage, which obviously leads to a heart attacks. Then we have oxidative stress.

4:53 So oxidant stress leads to the oxidation of LDL cholesterol, endothelial dysfunction, and direct damage to heart cells contributing to progression of heart disease. Obviously, that's huge and contributing all these things that end up causing heart attacks. Then, we endo-thelio dysfunction. Don't get intimidated by that, but basically, it's just how well our blood vessels function. So endothelial dysfunction impairs blood vessel function, leading to hypertension or high blood pressure, which eventually leads to atherosclerosis and increased risk of heart attacks and strokes.

5:23 And then we have metabolic imbalance. So metabolic syndrome, Dyslipidemia is obviously a major risk factor in heart disease. And a lot of people, for whatever reason, they know that this is a role in diabetes, but they don't necessarily make the link as much to heart diseases. Obviously, it's a huge thing. Especially too, when we talk about the peptides in a second, that's going to be massive in terms of determining what peptide to use. Let's now look at the peptide stack. So yes, BPC-157.

5:54 You're like, oh, come on, Harri. Pick the most boring, most popular peptides. There's no way Bpc- 157 has anything to do with heart disease, right? Well, not so fast. Let me look it up. Bbc 156 is obviously known for its regenerative and healing properties, and it promotes angiogenesis, which is the formation of new blood vessels And also tissue repair. So when it does this systemically, it also works on the heart. BPC helps support cardiovascular health by repairing these damaged blood vessels, reducing inflammation, which is obviously rampant,

6:25 and also protecting against ischemic damage, damage caused by restricted blood flow. So I know that's another intimidating word you hear a lot, but like ischemic, that just means damage caused by restricted blood flow, which obviously comes from, you know, for more or less lack of a better term being a flaming dumpster fire. So when we look at dosage or the context of heart disease, this would be a little bit different if you are looking to heal. If you're looking on the peptide cheat sheet, yes, it's a bit, maybe a different than the dosages there. Basically, we're doing 250 micrograms per day, five days per week administered subcutaneously.

6:57 I did it orally because PPC is available oraly, but for the context of helping with heart disease, you're just going to get much, much more benefit when you do a sub-cutaneous injection of it just into your belly. And you would typically take this in the morning alongside drum roll for next one, TB 500. So that leads us to the next, which is TB500, also known as thymus and beta-4. TB-500 is involved in wound healing and tissue repair. And what this does is it promotes cell migration and reduces inflammation. So in the context of heart disease, it's going to aid in repair of the tissue in heart and around the heart, particularly after myocardial infarction,

7:35 like a heart attack, and it also reduces fibrosis or scar tissue formation. Whether you're on the path to having a heart attack or have had one in the past, because I've talked to a lot of people that have that as well. TB 500 is massively beneficial. And again, this dose is a little bit different than you would use maybe if you had like a broken arm or something like that. But I would do 250 micrograms per day, five days per week, administered subcutaneously, taking the morning alongside again the BPC once The great thing too is you can buy from a research chemical company, of which I can't recommend publicly for obvious reasons to keep my channel afloat,

8:09 but you could buy a blend of those so you don't even have to buy them separately and inject two separate times. Or you buy then separately, and then put in the same syringe. You could obviously do that. And for recommendations on that, check out my how to mix peptides in same Syringe video that I released recently. Now, the next one, and this is going to hopefully take the world by storm over the couple years, is the peptide SS31. I think the name that you will also hear called is elamepritide. SS 31 is a mitochondrial targeted peptides that protects mitochondria from oxidative stress and improves their function.

8:48 So again, when we look at those four horsemen of heart disease, one of those is oxidative stress, and this is where SS31 really shines. So basically it enhances energy production in the heart cells. It reduces oxidate of damage to the hard cells and tissue and also is going to protect against heart failure. And I didn't cite them here because this was outside the scope of the video. There's numerous studies, I know in mice on SS 31 and what it does for heart health and mitochondrial function. For the specific use of, you know, heart-disease prevention or therapy.

9:19 I would use two milligrams five days per week administered subcutaneously. Obviously you could go up on that, but I know it can be cost prohibitive for some people. So the next one is going to be carnocene. And carnicene, you probably think of carnitine. Carnicine is a little bit less popular, um, I've actually played a lot around with lately injecting, and I definitely noticed something is going on that's beneficial here. So, carnosine is a dipeptide with strong antioxidant properties, capable of neutralizing free radicals and reducing oxidative stress.

9:51 And as it relates to heart disease, it's going to help protect the cardiovascular system by reducing oxytocin stress and inflammation, improving endothelial function and preventing the development of atherosclerosis, which is heart And so for dosing, what I would do is I inject 200 milligrams intramuscularly three to four times per week. And I'm typically going to do this in the morning because it does give you a nice energy burst. You can also take this orally, but in just my own experience, I have found the injectable carnosine to work wonderful.

10:25 Now I've gone as high as four grams of this and it works really, really well for endurance. at that level. But even at 200 milligrams injected, it does really well. So the next one is going to be RETA. Reta is a multi-receptor agonist. We have moved on from trisapatite now just because that is harder to get. I've been experimenting a lot with this lately. I actually made a video about it and well, I will just leave it to your imagination what happened when I tried to upload that to my channel.

10:55 So that video didn't get published, but RETA is a multi-receptor agonist, which works on GLP-1, GIP and glucagon receptors that helps regulate glucose and lipid metabolism. reduce body weight and improve insulin sensitivity. So again, with RETTA, we are attacking the metabolic pathway as it relates to heart disease. Uh, so Retta helps manage obesity and improves metabolic health, reduces risk factors for cardiovascular disease, and it also improves lipid profiles and reduces inflammation. So again, this is so, so powerful.

11:25 And my recommended dosage for this would be 0.5 milligrams subcutaneously every other day in the morning. I would just avoid consecutive days. You could do consecutive day, but I think for me, it just makes it easy. That's still a very low dose. So, relatively speaking, it's been really, really powerful for me. And I know a lot of other people because of the nature of what's going on in the GLP-1 research game right now are using it. So very, very powerful.

11:55 I don't think in terms of when we look at attacking that metabolic pathway, there's much more out there that we have right The next one, a little bit lesser known, but still very powerful is called ARA290. So this is derived from erythropoietin and has anti-inflammatory and tissue protective properties. For those of you from the sports world, you probably remember that was what Lance Armstrong got popped for back in the day, was using EPO, which is erytropoieten. This peptide is to ride from that. It reduces inflammation.

12:26 and promotes repair in heart tissue, which is beneficial for conditions like ischemic heart disease. And the dosage would be, when you do the math and just titrate it out, it's 1.3 milligrams per day administered subcutaneously for 30 days. Then you typically want to cycle that maybe, you know, three or four times a year, maybe more if it's really severe. But that's what I would do. And that one, again, it is going to specifically work on that inflammation and tissue repair in the heart. The next one is gonna be Fox04 DRI. So again a much lesser known one but very, very powerful.

12:58 You know, this one along with ARE290 are still like on the forefront of coming out. I mean, heck even SS31 is, but FOXO4 targets cellular senescence, which promotes the removal of senicent cells and reducing chronic inflammation. Basically, these seniscent cells are like zombie cells, meaning that they are existing past the time they should have died, at which end up causing a lot of oxidative stress on the body. And a lotta people struggle to clear these cells because as they age, their detox pathways don't work as well, and so we have these cell floating around

13:28 and they end causing, a bunch of waste products on body that causes to age more rapidly. Basically, this peptide will reduce chronic inflammation and improve heart function, especially in age-related cardiovascular diseases. What you would do with this one is three milligrams subcutaneously every other day for six days, and then you can repeat the cycle up to three times per year. It's not one that you're going to be using every day like some of the others. But you would kind of cycle it on and off. But again, very powerful. And a lot of people that I've talked to have used it, have really liked it. It's one of those like underlying peptides where you might not feel something right away, but it's definitely doing a a to the hardware of your body.

14:04 That's really, really powerful And then the last one, no, it's not a peptide, but yes, It is very helpful as it relates to heart disease. And that's going to be Tadalafil. So Tadelafill is a PDE5 inhibitor that increases nitric oxide levels, which leads to vasodilation, Which is the widening of the blood vessels and improve blood flow. Um, and it is commonly used to treat rectal dysfunction, But it has significant cardiovascular benefits, power and properties up to Dalafil. So it improves endothelial function, reduces arterial stiffness, lowers blood pressure, and also enhances cardiac output.

14:37 Anyone that has used it as a pre-workout can definitely attest to that. And it's particularly useful in managing pulmonary arterio-hypertension, which is high blood-pressure and preventing heart failure. The dose for that would be five milligrams daily, taken orally. That's a pretty low dose, but I think good enough and kind of the minimum effective dose to help with heart disease. So let's look at the four horsemen. So for the inflammation, we've got the ARA 290, the BPC 157, and the TB 500 and RETA TrueTide. The AERA 2 90 reduces inflammatory cytokines, BTC and TB promote tissue repair and reduce localized inflammation.

15:10 And then the Reta improves metabolic health, lowering systemic inflammation Then we have oxidative stress. So the SS31 protects mitochondria from this oxidant damage. The carnosine neutralizes free radicals in the FOX04, clear senescent cells, which is in turn going to reduce oxidated stress, and then we endothelial dysfunction. BPC repairs endethelal lining. Tadalafel improves nitric oxide production for better blood flow. Carnosine protects the endithelium from damage, And lastly, we have metabolic syndrome, metabolic imbalance.

15:43 So the RETA improves insulin sensitivity and lipid profiles. That's our cholesterol. And then the SS31 is going to enhance mitochondrial function and energy metabolism to really up-regulate the amount of energy we're going expand, which again, relates to our metabolism. so that's how we attack those with this. and then lastly I have the calendar. This would be what is beneficial if you want me to post the slides in that link. So you just got to remember to like the video. If it gets 500 comments, I'll post all this. You can download it and have it as a spreadsheet for yourself.

16:13 It's pretty simple. In the morning on Monday, you'd have Tidalofil, BPC, TB 500, and RETA. And then the evening you have SS 31 and ARA 290. Tuesday, Tidalofill, Cornucine. Then in the even you would have TB500 and BTC, which you can always do in evening as well as the Then Wednesday, we have the Tidalafil, BPC, TB, Reta, ARA290, and the evening, SS31 and FOX04. And then we kind of go from there and you get the picture. So again, most of these are not ones you're going to really have to worry about taking in the morning or evening.

16:44 None of them are necessarily going be like stimulatory to keep you awake at night. But that's just kind the calendar that I planned out. Again, if it gets 500 likes, I'll post that so you can have that. Uh, for reference there, or you can screenshot it if you want to. I know people ask me that all the time. So that is it for the slides and that. Is the comprehensive peptide stack for heart health. Hopefully that was helpful to you guys. Um, again, pretty simple. It doesn't have to be anything crazy. And obviously too, this is going to work best when you're optimizing your hormones, when are living a low body fat lifestyle,

17:14 meaning that you are eating healthy, you fasting on a regular basis, um, your training with weight or doing cardiovascular disease. None of these peptides can replace that and just remember that. I know that I say that all the time, but hopefully this was helpful to you guys. So if you have questions, comments, concerns, definitely drop a comment below. Also, don't forget, if have you questions there is a link in every video to submit a video topic request or question to me. And those are the ones I'm using for my Q&A videos now. Um, so I can't respond to every comment, but I do my best to look at those, uh, emails that I get and put those questions in the Q and A videos.

17:45 So, um, hopefully you guys enjoyed that. Remember 500 likes and I'll post the slides and then, yeah, much more to come. Stay tuned. Appreciate you, guys. Love you. And I will see you in. Peace.