HGH Peptides vs HGH How To Combine Them For Maximum Benefit

0:09 Hey everybody. This is Hunter Williams. I hope you were doing amazing wherever you are at in the world today. Today's video is going to be about using HGH peptides with human growth hormone itself. And this is definitely, I would say a large chunk of the questions I get are around growth and peptide, which I think is great because they're amazing. They do amazing things with the body. Especially if we look in a context of anti-aging and longevity when used properly, there's some of those powerful things we have out there. Uh, to date that we know to help, um, stem the title page.

0:41 So what I wanted to do today, uh, cause this is a very common question I get, and I haven't fleshed out in the whole video yet is explained the use case of using growth hormone itself alongside an HTH peptide and why we would use those. I don't do this all the time, but I have done it a lot and plan to probably do it much into the future. Um, because I, I think there are certain use cases where you could use both of them together to achieve a certain outcome. I could, I'd think you can even draw the analogy that using an HGH peptide with HCH itself is akin, not identical, akin or alike to using HCG alongside testosterone.

1:26 And I know those are very different things, but if you kind of think of like supporting the body's own natural production while also supplementing with the hormone itself, I think it's very akin to that. Now, will we do this all the time? No. I Think HGH is the gold standard when it comes to this. You know, rated pharmaceutical grade HCH is gold-standard when comes growth hormone supplementation or optimization. However, there are use cases where we can use peptides alongside that to achieve a certain outcome. So that's what I'm going to walk through today of which peptide we would use, why we would use them and what we use for alongside of growth hormones.

1:59 We'll see how this does. I hope it is entertaining and educational and informative to you guys. So I'd appreciate the feedback in the form of comments and everything like that. But before I jump into the slides, I just want to say thank you, guys, so much. at the outpouring of support I get. You know, so if you want to head over to the email list, check out the peptide cheat sheet, and also check our fully optimized health, which is the best private community on the planet to learn about peptides, hormones, all that good stuff. So without further ado, I'm going to share the screen. And today we're going learn, about using HGH Peptides alongside of growth hormone itself.

2:33 All right. My name is Hunter Williams. Today's video is, can we use HGH with HCH peptides at the same time? And I'm going to be walking through my do's and don'ts. So let's get into it. Obviously if you're here, if your watching this, you know that HTH for therapeutic and performance enhancing purposes has become the gold standard, like I said. But when we combine it with growth hormone-releasing peptides such as Tessamerelin and Ipamerelin, it creates this cool, unique synergy that I think has not really been talked about that well, but I've done a lot with myself and seen in a lotta clients.

3:03 And the method not only enhances our natural growth-hormone pulsation but also provides added benefits that standard HGH therapy alone may not achieve or without the HH might not achieve without running the risk of extra side effects, which are not always bad, but, um, we want to mitigate side-effects as much as possible. So let's first just kind of compare. And for the sake of this video, I'm going to be talking about Tessamerelin or Ipamerelin. You could throw in like CJC or Hexrun or some of these other ones that are popular that people like to talk about or shoot,

3:33 even, uh, Ceremorelin, you could turn that in. But I would say Tessemereline or The go-to when I'm using these are those only ones that I personally will use. But again, you can use other ones. Um, but I want to like outline how they work differently, um, just to give a overview of that. So HGH is a naturally occurring peptide hormone secreted by our pituitary gland. It simulates cell growth, uh, reproduction and regeneration and administering exogenous HCH increases serum IGF-1 levels,

4:03 promoting muscle growth fat loss and improved recovery. Now, let's look at Testimelan. So, Testimon is a GHRH, which stands for growth hormone releasing hormone analog, that stimulates the pituitary gland to release endogenous HGH. It's well known for reducing visceral fat, especially in the lower abs, and improving metabolic health without causing desensitization of the So let's look at ipamrelin, a little bit different in terms of like its chemical structure to testimrelon. So it's a selective growth hormone releasing peptide that mimics ghrelen.

4:35 It stimulates the pituitary gland to release growth hormones in a pulsatile manner. so it is renowned for its minimal impact on cortisol and prolactin making it a safe option for extended use. I think you probably, in term of looking at side effects and attenuation or tolerance built up to the peptides, Ipamrelin, you can probably use a little bit longer than Tessamrelin. So it kind of depends on the person, man or woman. But I would say ipamrellin is actually probably the best gateway peptide, meaning that pound for pound in terms of if you look at benefits relative to

5:09 side effects. I think it's like the best profile in that sense. So if someone's new to peptides, um, I usually recommend it because you're going to sleep better. They're gonna burn fat, build muscle better, they're, gonna feel overall better and by itself has relatively no side effects for the most part. Can't say, you know, blanket statement, but, uh, You know like injection pain, injection issues, Um, like water retention and everything, and I, think is the, best like gateway peptide. And then people can get in comfortable with peptids and then kind of, build their own reference range from there.

5:43 So, let's look at the synergies of combining HEH with HE peptides. When we use HE alongside Testimonella and Iporella, it is leveraging this exogenous and endogenous mechanisms, which creates a dual pathway to optimize the levels. First it's going to enhance the pulsatility. How about that for a word? Um, it promote intestinal and encourage natural growth hormone secretion in arrhythmic pulses, which compliment the steady, steady elevation from exogenous HGH.

6:14 So this mimics our body's natural hormonal rhythm. We're going to go into like timing around that, like morning and night, night timing. Now even exogenous HCH still pulses cause it's got a pretty short half life. I forget off the top of my head, somewhere probably around like six to eight hours. But when we look at it, it's going directly into the body. So it is coming from an external source rather than like stimulating our own source. The second benefit and synergy I would say to this is combining the peptides with the exogenous HH allows for lower HEH doses while achieving comparable benefits.

6:48 To reduce the risk of side effects like insulin resistance or edema, which again, if managed properly, you don't really have to worry about those. However, if we look at like, okay, can I use two IUs of HGH and a milligram of tessameralin or two milligrams of Tessamaralin instead of having to do six Ius of HDH? Because while some people may respond great to six, I used of hgh, you may be able to get almost close to the benefits for a short period of time without the side effects. So we'll look more at that, but It's going to have targeted benefits.

7:21 I think this is where you could make the argument. This is the most useful is that testosterone's metabolic improvement such as visceral fat reduction pair well with the the anabolic nature of HGH. Not that HCH doesn't help with fat loss, but it's kind of like, I think testosterone pound for pound burns more fat than HTH. Obviously you can look at dosing to see what does better, But then that comes into like managing any sort of side effects. And then also, ipamrelin further supports recovery, sleep quality, and muscle repair. Then it was also to, if this is ever a concern, And for some younger people, using peptides help maintain pituitary gland function and prevents long-term

7:56 suppression that may occur with HGH therapy alone or HCH monotherapy for the long haul. You know, I personally don't fret about the suppression of the pituitary from HGH as much as I would something like testosterone therapy, but then the last there still is a negative feedback loop there. And I think when we look at the peptides, like I was comparing with HCG, you can kind of like, in theory, make the same argument, so let's look Use cases. So what are some practical applications and dosage?

8:27 So let's look at these and understand like why we would do certain things. I'm going to kind of pull up like these different use cases and explain like what we do. Human growth hormone, so the typical dosages in synergy with a peptide would be one to two I use per day. You could go higher if you wanted to, but I think again when we look You know, not in the context of bodybuilding, it's not the contexts of like driving as much mass muscle mass as possible or getting down to like 3% body fat. Um, when we look at like anti-aging longevity in these use cases, that's what I would do.

8:58 So why does this work? So dividing the, um, dosage helps replicate the body's natural biphasic growth hormone secretion pattern higher at night and lower during the day. So the reduced likelihood of overloading the system and maintaining optimal IGF-1 levels. Research shows that low dose HTA therapy improves metabolic function, body composition, and recovery without causing significant side effects such as insulin resistance or water retention. So again, when we're looking at just the growth hormone, this is why, you know, for these purposes, one to two IU per day works great.

9:31 For example, a study published in Indocrine Reviews highlights that lower dose HEH reduces side-effects compared to high dose protocols while achieving more or less similar anabolic benefits. Um, so if I were just using HE itself, I would do HGH in the morning to align with natural fasting states where insulin levels are low, enhancing the efficacy for fat metabolism. And then an evening injection, I will do to support recovery muscle pair during the body's nocturnal healing process and to assist with sleep. So that would be if we were just doing HTH, but now Let's look at what if I was just doing Tessamerelin.

10:05 So what I would do is one to two milligrams subcutaneously in the evening. Testamerelin stimulates the pituitary gland to release growth hormone, which amplifies the natural surge that occurs during sleep. This aligns with the body circadian rhythm, ultimately maximizes IGF-1 production and the repair that we're looking for. So there was a study in Journal of Clinical Endocrinology and Metabolism demonstrated that testosterone effectively reduces visceral fat and improves IGF-1 levels in patients with lipodystrophy, which is basically a lot of visceral body fat that a lots of times stems from HIV or AIDS,

10:41 and metabolic disorders. So these findings support its ability to enhance body composition while protecting against growth hormone desensitization. So testosterone selective action on visceral adipose tissue makes it particularly useful for individuals with metabolic syndrome or stubborn central fat. And then you would take this at the evening, obviously because it works synergistically with the body's peak HGH secretion enhancing nighttime recovery and fat metabolism. We look at testosterone that really relative to HHH itself, it's going to shine when it comes to fat loss.

11:11 Now let's look it from Maryland and kind of like what we can expect around it. So this is going be 200 to 300 micrograms subcutaneously, one to three times daily based on the desired level of support. And so it stimulates growth hormone release in a controlled manner. Producing predictable pulses without overstimulating cortisol or prolactin, making it safe for more frequent use. So administering Ipameral and post-exercise has been shown to amplify the natural HGH surge induced by physical activity. Research in Peptide's journal has highlighted its ability to promote muscle repair and recovery with minimal side effects.

11:45 And then other, unlike other peptides like GHRB6, ipamrelin does not significantly raise appetite or prolactin levels, which in my opinion, I feel like HGH does. The more HHH I take, definitely get hungrier for obvious reasons, but it makes it suitable for individuals focused on body composition that are especially trying to lean out. And so timing wise, I like it injecting at 36 minutes before a workout to enhance the body's natural exercise, induce growth hormone surge, improving recovery and fat oxidation. If you're really anal retentive, you could do it before and after exercise and obviously pre-sleep.

12:17 So it works synergistically with testosterone, so maximizing nocturnal HGH pulse at night to support deep sleep, tissue repair, and muscle growth is possible. Let's look at the timing of using all of these together. So evening injections of tessameralin and iparelin amplify natural growth hormone pulses rather than suppressing them, ensuring the pituitary gland maintains stability to secrete HEH naturally. So this approach prevents the down-to-regulation, same with long-term exogenous HGHUs alone, like we talked about.

12:49 And then morning HTH administration complements the natural nocturnal growth hormone peak, which balances the 24-hour secretion pattern and provides continuous anabolic and metabolic support. So you can see where we're going with this. And then we have an exercise in due synergy. So HGH and peptides administered around workouts enhance the body's anabolic window where nutrient uptake and muscle repair are maximized. And the additional growth hormone surge from epinephrine strengthens these effects. There was a study published in Sports Medicine confirmed that HTH released during exercise peaks about 30 minutes into activity,

13:22 which can be amplified with peptide timing. That's why, you know, again, taking a pre-workout. And then we look at fat metabolism optimization. So fasting states in the morning create in an ideal environment for exogenous HGH to promote lipolysis, which is burning fat as insulin levels are the lowest. And similarly, Tessamerelin in evening targets visceral fat more effectively due to its alignment with nocturnal HCH secretion. Let's look a practical protocol if we were to use all of these or even just two of them. So in the morning I would do one to two I use subcutaneously of HEH itself to enhance fat metabolism and energy levels.

13:59 Pre-exercise, I will do 200 to 300 micrograms of Ipermellon to amplify the HEh response during training. And then pre-bed, would take one or two milligrams to maximize nighttime recovery and fat loss. If you wanted to, You could add in another 200 to 300 micrograms of ipamrelin to enhance sleep. I would say if you're doing two milligrams of testamrealin, you don't really need the ipamelin. But if we're going one, You can argue that, hey, adding in 200 or 300 of Ipamrelin would be good there too. So, what are the use cases of this?

14:30 Fat loss and metabolic optimization. So this would be if I am trying to maximize fat loss. Obviously, testosterone reduces visceral adipose tissue, HEH enhances lipolysis, and amperomereline complements both of these by amplifying growth hormone. I would do morning HE, pre-bed Tessamerelin and pre exercise Ipameralin. So again, use case for most fat loss possible. That's what I would do. Now let's look at muscle growth. We can also use these to enhance muscle grow.

15:00 I'd do morning HGH, pre workout Ippamerelin and Pre-Bed Tessa Merlin again. You say, why is that different than fatloss? That sounds like the exact same thing. Yes, it is the same exact thing and the difference between the fat-lost and muscle-growth is going to come in the calorie deficit or the calories surplus. So again, if we are looking at those things, The growth hormone optimization protocol that we're doing is doing just that. It's optimizing growth hormones.

15:31 And whether we are going to build muscle or burn fat or do both kind of comes into nutrient timing. So I'm not going get into that in this video, but again, it's going be the same thing. We've got anti-aging and longevity. Again, that's gonna be same. You know, for anti aging purposes, I don't know that I would need to put Testimonella and Impronolella together. So I would do a low dose of HGH in the morning, like one IU, and then one milligram of tessameralin in evening. And then you could just alternate the tessemeral and imprimralin back and forth, you know, over four to six weeks periods,

16:03 if you were focused on like a cycle of four or eight weeks of just anti-aging. Now, let's look at athletic performance. I would, again, do HGH in the morning, Ipameralen pre-training and potentially after training. Or what you could do is do Ipmeralin pre training and then Testimeraline post training, and also do Testimaline pre bed. So again if you're playing a sport, Performance is the goal to be able to recover as much as possible. ACH first thing in the morning, Hippomerelin pre-training, Tessamereline post- training, and then Tessa Merelline pre bed.

16:37 And if I was doing that, I would do one milligram of Tessemerellan post training and one milligrams of tessmereline before bed Post injury recovery. This is actually like very important. And this is another use case where I would say just HGH alone might not be enough. Or again, it might cause too much side effects when we're doing a higher dose. If you were to have a surgery or get injured or some traumatic event or something like that, I wouldn't use all three of these. So I will do morning HHH for the anabolic support. Tessamerelin pre-bed for the metabolic repair and Impramrelin as needed for additional recovery boost.

17:12 Obviously, you wouldn't do the Impromelin around training because if you're injured, your probably not training that much. But you could either alternate between Tissamerelin or Imbramrellin, or you can just do like one milligram of Tismerellin before bed and then 200 to 300 micrograms of Imrum before But as you probably know, those are all part of the Wolverine healing stack to help with healing. So obviously, you want to use BPC, TB 500, PEG, MGF, and GHK with those. But if someone was going through a surgery or something like that, I would absolutely, without a shadow of a doubt, use these.

17:45 And so why would we do this overall, just to sum up? So I think, again, for those use cases we just described, we're maximizing results with lower risk. I've taken higher doses of HEH up to like six to eight IUs. I do like it, but there is a little bit more of a side effect profile, especially for me, I'm not trying to become like a, you know, 280 pound bodybuilder that I don't necessarily just want the extra mass and extra water retention, But I like the fat loss benefits that get from like 6IUs of growth hormone.

18:15 That does come at a cost though, and we just have to decide for ourselves what that cost is. But I think to maximize the benefits, we can lower the risk profile of getting higher levels of growth hormone in our body when we use this method. So combining these compounds reduces the need for higher doses of exogenous HGH and minimizing the side effects like insulin resistance or water retention. I ultimately think for me too, how can I drive as much IGF as possible that's healthy without the side effects of water retention that becomes like the

18:46 game you have to play with growth hormone and growth from on peptides. But whether we're focusing on fat loss, muscle gain or overall health, the flexibility of timing and dosages allows the protocol to fit specific objectives and obviously support for aging. So for younger individuals, this combination provides a way to safely restore growth level levels without suppressing natural production. in their 30s and 40s, this is a good way to get the best of both worlds. And if you are concerned about pituitary suppression, I think just based on my own research and everything, that it's the thing that you can do if that's

19:19 a concern. Then by leveraging both exogenous HGH and peptides, we can address multiple health and performance goals simultaneously. Like I talked about with the building muscle and the burning fat, something neither approach can achieve alone. Like I said, I wanted to make this comparison and maybe I'm crazy. Maybe this is completely wrong, but I thought of the, you know, is this similar to TOT with HCG? So when we have, uh, TRT with ACG, the body's natural production of testosterone, and the testes is suppressed because of HPG axis,

19:49 detects sufficient levels of testosterone in the bloodstream. So we use HC to stimulate the lytic cells in testies to produce testosterone. and maintain testicular size and function and also fertility. When we have HGH with peptides, when we use exogenous HCH, the body's natural production of growth hormone can be suppressed, it's less likely, but it can suppressed due to feedback inhibition of the hypothalamic pituitary axis. So HTH peptide like Tessa and Ipah stimulate the pitutary gland to release endogenous growth hormones, preserving the glands natural functioning and preventing

20:21 atrophy over time. So does it lower the risk of long-term suppression TRT with HCG? Yes, it does. It can lead to testicular shrinkage. Testosterone can to lead testicular shrinkages, infertility, and complete shutdown of endogenous testosterone production by itself. But HCT mitigates these risks, making it more sustainable for the longterm. And then HGH with HCH peptides, long term HTH use without peptide can leads to pituitary suppression and desensitization. And so when we add peptides like Tessa and Nipah in, the natural signaling pathways remain active, allowing the body to maintain its ability to produce

20:54 growth hormone endogenously. So I know no one's really talked about that before, but just a thought that I have. That is it for the slides. And that is how you would use HGH with HHH peptide at the same time. Again, this is something that maybe doing one or two times throughout the year. maybe in like a fat loss phase where I'm really trying to get lean. I want to give the extra benefit of the testosterone or upper melon. Um, fortunately for me, I haven't been injured, but if there was an injury phase, definitely would. And then also too, um, you know, for a muscle building phase probably like four to six week window, You could do this just to kind of take the load off

21:30 of higher dose HGH. If that's some things you were doing. So again, really not like what I would tell a bodybuilder, body builders love higher doses of growth hormone and rightfully so. But I think for the anti-aging longevity, health-focused community, and just want to look good naked, there definitely is a use case of lower dose, precise dose of HGH with some of these peptides, whether it's just to maintain any sort of defense against the pituitary suppression or to get the most bang for our buck. So I when we look at the risk profile of doing this, it is kind of like the best of both worlds where we can probably push the benefits we're getting from

22:05 the IGF and HTH a little bit more then we would without having to worry about some of the water retention or insulin resistance that results. So hopefully that was helpful to you guys. This is a very common question I get. Hopefully this made sense and I would love to hear your feedback, good or bad on this one. But don't forget, check out the email list. Peptide cheat sheet will be down below. and then also to join Fully Optimized Health's best community out there on the planet. So much love. I appreciate you guys. Thank you so much for all the support I get.

22:35 You know, I'm humbled and grateful to the max every single day of what I can do and bring to you, guys, so thank you. Love you and I will talk to in the next one. Peace.