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Peptide Q&A · Fat Loss, Hormones, and More

2026-03-29 · 39:47 · 7 min read

These Q&A videos are turning into some of my favorites because the questions keep getting better. I'm going to power through a stack of them today. If you want your question answered next time, the suggestion box link is in the description of every video.

Should you buy raw peptide powder?

Someone asked how I weigh out raw peptide powder and put it into vials.

I don't. I never buy raw peptide powder. I never reconstitute raw powder into vials myself. I only buy from places that have peptides already lyophilized and in a vial.

Unless you're a chemist with a full lab, don't try to synthesize peptides on your own. If anything I said in past videos sounded like that, I apologize. That's not what I do.

Kisspeptin for women

Kisspeptin can help slightly boost testosterone, improve fertility, and help with mood dysregulation from unoptimized hormones.

The downside is the short half-life. You'll inject frequently. And like other peptides, long-term use means upping the dose or coming off.

Compared to nothing, it's good. Compared to testosterone therapy, it's pretty worthless. Check out my video on women and testosterone therapy. You'll be much better off going that route.

Are peptides different for women?

Most popular peptides dose and metabolize the same for men and women.

The one exception that comes to mind is growth hormone peptides. Women typically respond better to ipamorelin. Men typically respond better to tesamorelin. Either sex can use either. That's just my general observation.

Cycling between peptide stacks

Someone asked about doing CJC/ipamorelin/BPC-157/GHK-Cu for eight weeks, then switching to retatrutide and LL-37 before going back.

Absolutely fine. No issue rotating like that.

Oral testosterone vs injectable

The CEO of Marius Pharmaceuticals claims their oral testosterone undecanoate frees up more testosterone with fewer side effects than injectable.

I'd be skeptical. I see no evidence to suggest that, even with sublingual formulations. Most veteran testosterone users always come back to injections.

I'm not calling anyone a scammer. Oral T is better than nothing, and the world would be better if more men had access to something. But injections are usually cheaper and work better. Why wouldn't I use the thing that works better?

Desiccated thyroid

I already have a deep video on this. Standard starting dose is 60 mg of desiccated thyroid. That's Armour Thyroid, NP Thyroid, or Nature-Throid. Titrate up or down based on response.

A lot of people are scared of thyroid because they're thinking of synthetic stuff like Cytomel or Synthroid. Desiccated thyroid is different. It's extracted from porcine (pig) thyroid. Same idea as the beef thyroid supplements you can buy on Amazon, just pharmaceutical grade.

Desiccated thyroid is not something I lose sleep over. Most people on hormone optimization could benefit from it.

Microdosing PT-141

Can you microdose PT-141 daily instead of doing 8 full doses per month?

Yes. When I've used 1.5 to 2 mg, the effects sometimes last 24 to 48 hours. Honestly that dose can be overwhelming in a way that becomes uncomfortable.

Cutting it down to 250 to 500 mcg daily should give you a similar therapeutic effect without being so exaggerated. Same for women using it for libido. Some people get nauseous, so start low.

Peptides around gynecomastia surgery

For BPC-157 and TB-500 around surgery, I'd start about four weeks before. After surgery, run them at least 8 to 12 weeks, or really until you heal.

No reason to stop tirzepatide or retatrutide before surgery. If anything, they'll help with healing.

Lyophilized vs raw peptides in vials

Lyophilized peptides have preservatives added so they're more stable with longer shelf life. Raw peptides in a vial don't have those preservatives, so the vial almost looks empty.

In my experience I respond the same to both. People ask about preservatives like mannitol, whether they cause inflammatory responses, lipopolysaccharide concerns. In theory, yes, that could happen. In practice across many research companies, I've rarely seen issues. About 85% of the research peptide market comes from the same general place, and most aren't trying to sell you bad stuff.

Help for the 24-year-old, 235 lb, struggling-to-lose-weight guy

This guy is killing himself eating salad and protein once a day, running, lifting, and the scale won't move. AOD-9604 stood out to him from his research.

Here's the truth. This describes 70 to 80% of 24-year-old men right now. They've been working hard with no real guidance and they hit a wall. The wall is hormones.

I'd bet money this young man has very low testosterone. Your doctor will never put a 24-year-old on testosterone therapy. I would. Immediately.

Then add desiccated thyroid because your thyroid has stalled out from chronic restriction. You need it to up-regulate metabolism. Add metformin or at least berberine for insulin sensitivity. Keep lifting weights.

For peptides, I'd skip AOD for now. Use tesamorelin for growth hormone support and microdose retatrutide. Doses are on the peptide cheat sheet. From there you can add SLU-PP-332 and a mitochondrial peptide like MOTS-c or SS-31.

Hormones first, always. Doesn't matter if you're a man or a woman. Get testosterone and thyroid handled, throw in an insulin sensitizer, then layer peptides on top.

SLU-PP-332 oral dosing

It comes in a 30 mL bottle with a dropper, and each 1 mL contains 100 mcg.

Start with 1 mL (100 mcg) and see how you feel. Most people do better at 200 to 300 mcg, which is 2 to 3 mL.

Fertility stack for a 46-year-old

Already on enclomiphene, tirzepatide, and a long list of supplements. Wants to add to it for fertility.

I'd add HCG at 1000 IU three times per week. More importantly, add HMG at 25 IU three times per week (75 IU weekly total). Add injectable glutathione at 500 mg once per week.

You could also add injectable L-carnitine at 500 mg three to four times per week.

The GLP-1 will actually help with fertility because it heals metabolic dysfunction. Lots of fertility issues are downstream of metabolic problems.

I'll probably do a deep dive video on fertility stacks soon.

Tesamorelin/ipamorelin blend dosing

For a 10 mg tesamorelin / 5 mg ipamorelin blend, I'd target 500 mcg tesamorelin and 250 mcg ipamorelin per dose.

Add 2 mL of bacteriostatic water to the vial. Use 10 units (0.10 mL) per injection. That gives you 500 mcg tesa and 250 mcg ipa per shot. Use the peptide calculator if you want to double-check.

Metformin and birth defects

A 45-year-old wants metformin but saw a study saying it could cause birth defects in his future kids.

Worthless study in my opinion. What are the chances that diabetic men have higher rates of birth defects in their children? A lot higher than the general population. So a diabetic man on metformin probably has the same elevated risk as the average diabetic, not because of metformin.

Free testosterone of 126, total of 1475

If you have no side effects and your other blood markers are fine, no, that's not too high. Sounds about right for a total T of 1475. I wouldn't worry about it. Doctor opinions on this vary, that's just mine.

Pins, needles, water retention on CJC-1295 with DAC

This is exactly why I don't recommend CJC-1295 with DAC. The DAC extends the half-life dramatically, which causes water retention, that pins-and-needles feeling, and the brutal injection site reactions with itchy lumps.

Throw the DAC version in the trash. Get CJC-1295 without DAC, or just use ipamorelin and split the dose twice a day. The side effects will almost certainly disappear.

Pre-loading syringes

Yes, you can prep your week of injections on Sunday like meal prep. Keep them refrigerated.

I wouldn't go beyond two weeks. The peptide solution sitting against the rubber for too long can get a little thick and not inject as smoothly. Within a week, you're fine.

47-year-old woman with constant tendon issues lifting

Knees, tennis elbow, aggravated tendons every time she pushes the weight up.

This is hormonal first. A 47-year-old woman is most likely testosterone deficient and probably approaching or in menopause. As estrogen drops, your connective tissue feels awful. I know because my own estrogen has crashed multiple times and that's exactly the feeling.

Get hormones addressed before chasing peptide solutions.

Retatrutide vs tirzepatide

Tirzepatide is probably a bit better for appetite suppression. Retatrutide is better for fat loss. You can stack them together for serious results.

Peptides for winter and seasonal mood

Melanotan-1 and thymosin alpha-1 are my go-tos. I'm using thymosin alpha-1 right now to support immunity. Melanotan-1 enhances absorption of the limited sunlight you do get.

GHK-Cu copper toxicity

To even approach the upper recommended daily limit of copper, you'd have to inject around 55 mg of GHK-Cu in a single day. Most vials are 50 mg. And it clears the body in about 12 to 16 hours.

If you're injecting 2 to 5 mg daily, you're nowhere close. Don't worry about it.

Clenbuterol and stimulant fat burners

Someone asked about Super Helios (likely clenbuterol and yohimbine).

I stay away from clen. If you have albuterol, that's enough. If you have SLU-PP-332, that's enough. I know what injectable albuterol feels like and I have no interest in finding out what injectable clen feels like.

I'm not a stimulant person. If that's your thing, fine. Not me.

Cycling peptides

Ask yourself, what's more damaging? Staying on the peptide and increasing the dose, or coming off it?

If you're severely overweight or have a severe injury, the damage of stopping is bigger than the damage of staying on. Stay on, increase the dose if you need to.

If you've already hit your goal and you're maintaining, cycle off and rotate in another peptide. The answer depends on what's actually at stake for you right now.

Peptides for post-menopausal women

Yes, 1000%. But every post-menopausal woman should be on hormone replacement first. Testosterone, estradiol, and progesterone. No questions asked.

If you're looking at peptides as a post-menopausal woman without hormones in place, nothing is going to work right. Your body needs the hormonal foundation. The fact that frontline care for menopausal women isn't HRT is one of the things that genuinely infuriates me about the medical establishment.

NMN vs injecting NAD+

People take NMN orally because NAD+ has to be injected to be effective. Supplement companies can sell you something you swallow, and most people don't want to inject.

If you're already injecting NAD+, adding NMN doesn't hurt because it acts as a precursor. Using them together makes sense. The "just take NMN, you don't need NAD+" pitch is mostly marketing.

My take

The pattern across most of these questions is the same. People reach for peptides before they've fixed the hormonal foundation underneath. Testosterone, thyroid, insulin sensitivity, estrogen and progesterone for women. Get those right and the peptides actually do what they're supposed to do. Skip that step and you're spinning your wheels.

Thanks for sending these in. Keep them coming through the suggestion box and I'll see you in the next one.

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Full transcript click any paragraph to jump video

Hey, you're right. This is Hunter Williams. I hope you were doing amazing wherever you at in the world today, we have a Q and a video. So these are actually turning into be some of my favorite videos because the questions are getting so good. so I'm not going to do a bunch of intro for this video, I'll just going pull up my screen. Uh, won't share it with you guys to protect names to the innocent, but, um, just turn it into really good videos, because of the question I am getting are so, so the only plug I will make for the video is check out the link in description of every one of videos.

I have a little box you can submit a video topic suggestion or question, or if you just want to send me something like research or whatever. A lot of people do that now through that. So that's a perfect place to go. If you want your question answered on these videos, head there and that where I get these from. I've got them pulled up. Some of them I'll probably have to filter through because there are a lot just like random questions like, how do we get the peptide cheat sheet? I usually get like two or three questions a day of like how I got the Peptide Cheat Sheet. Unfortunately, all I can say is it's not me. There are hundreds of per day that sign up for that and get it.

A lotta times it is your email provider. It's security restrictions you have around your e-mail. So again, that's not me. And I usually reply to those people and do what I can to get it to them if they can't do it and I'll just send the attachment. But anyway. Let's get into it. And we've got some good ones today. Some of these are a little bit longer. So we'll just wrap and see how long this goes. Let me pull it up and go through these questions. We will just start knocking them out.

I may have a voluntary pause in between some of this. But first one, this is actually a very in-depth question. I don't think it will be relevant to a lot of people, but I think its still an important answer. So someone said, I would like to ask for guidance on how to handle raw peptide powder. I've watched you and James videos that basically say that raw powder is basically the same as its vile package form is. You also mentioned that you mostly buy raw power these days. It's much cheaper, isn't it? My question is, what tools do you do to exactly weigh five milligrams of rawpower, which is a very small amount, and put it into a vial for reconstitution?

I wouldn't be done without the advanced lab equipment. never, never do that. I don't ever buy raw peptide powder, and I'll never put raw type powder into vials. So I only buy places that I know for research have peptides that are already lyophilized and are in vial. Never, ever do, that, I'm sorry if anything I said came across as that to be that so never buy, raw, peptid powder and try to synthesize it on your own, unless you're a chemist and have a full lab to do so of which I am not even, so.

Next question is, I would like to see more videos on bioregulators if you have knowledge. Stay tuned, that will be coming. Kisspeptin for women. Kispepton for woman's great. The pros of it are that it can potentially help with boosting testosterone levels slightly, improving fertility, and also helping with some mood dysregulation that women have from unoptimized hormones. On the cons are, it has a really short half life, you'll have to inject it pretty frequently. And like other things, it's a peptide, so if you use it for a prolonged period of time, you're going to either have to up the dose or come off of it.

So relative to nothing, its great. Relative to testosterone, It's kind of worthless. I would say check out the video I have on women in testosterone therapy and you'll be much better suited if good on that route. Another question specifically for women, are there peptides that work best for woman by indication? Do they have the same effects? Are there any women should avoid? Or are they metabolized the thesame? Honestly, not really. I would say for the most popular ones, they're pretty much going to be the sames dosing, the samest metabolization for wome.

When you look at growth hormone peptide, women typically respond better to ipamrelin. Men typically responded a little better testmrelon. Not that either can't use either. But I would say offhand, that's the only thing that comes to mind that I think you would maybe, you know, for the most common peptides that you'd see. Um, let's see. After doing a cycle of CJC 1295 and Ipamerelin, BPC 157 and GHK CU for eight weeks.

Can I do Reddit True Tide and LL37 my next cycle for a week before I go back to my first cycle? Absolutely. I see no issue with that whatsoever. And if you want to rotate in between and do that, that sounds good to me. Don't know anything about your goals. but I think that would be good. Here's a good question. I definitely wanted to talk about this one. How about oral testosterone versus injectable testosterone? The CEO of I don't know if it's spelled right, Marius Pharmaceuticals, I dunno, say that his oral TU, which is testosterone undeconite,

frees up more testosterone, has less side effects than injectable T. I think whoever is saying that, and I know them, but I would be very skeptical of them. So from what I now, don' see any evidence to suggest that. That would just not make sense, even if its a sublingual formulation. relative to injectable testosterone. However, they do know that more people will buy it because a lot of people weren't scared to injection needles. So in my experience, most veteran users of testosterone always come back to using testosterone injections.

That's my opinion. I'm sure it works better than nothing. And again, I don't want to make it sound like that person's a scammer. Um, I didn't know them, so I can't say, but like oral testosterone and deconate is almost better, a guaranteed better than nothing that you have. So like the world would be a better place if more people had that. I. Don't think that's necessarily like a bad service, But it's just like, eh, why, if I could have something that is cheaper, which injections are typically cheaper. That has better effect. Why am I not going to use that? Of course I am. Uh, next one.

Um, hi, what'd you think about doing a video on the use of desiccated thyroid? I actually already have, uh, so that I have an extensive video and desicated thyroid. If you want to look that up. Um. Yeah, I think it'd be beneficial on dosage amounts, frequency. Uh, yeah, absolutely. You can check it out. I do have it. It's typical standard dose of 60 milligrams, desicate thyroid get started. Obviously that would mean you can use armor thyroid, MP thyroid nature thyroid um, and use that. And that would start from there. You may have to titrate up, titrated down based on your response.

But I think everyone, particularly people using hormone optimization could definitely benefit from supplementing with thyroid. I will say, I this would be useful for everyone to understand. When it comes to thyroid, one, it's very hard to look at lab ranges and treat the thyroid and that's why a lot of people fail to treat their thyroid properly at least. Also, when we have thyroid, a lot of people are scared of taking thyroid but what they really think thyroid is, is synthetic thyroid like Cytomel or Synthroid,

dust cage thyroid it's much, much different. It's actually extracted from porcine thyroid or pig thyroids, the same way that you can go on Amazon and buy beef thyroid. the pharmaceutical version just comes from pigs, but it's a natural thyroid version. It's very common for people to use beef liver supplements or beef thyroid supplements, or be thymus supplements for whatever. Um, so I would say in terms of the things that I lose sleep overnight, the fact that they use desiccated thyroid is not one of them, meaning that, I'm not worried about that. In terms like the side effects or anything like that because if there was a pharmaceutical that was like a national thing,

desicated thyroid would be one that that would Um, this is a really good question too, which is about PT 141. So someone said, can PT one 41 be microdose daily versus only using eight times per month at a full dose? I think the answer is absolutely. You know, it doesn't have a super long half-life. I don't, I, don' remember it off the top of my head. But I think for a man or a woman, you could definitely use it at a microdose probably to achieve the same relative therapeutic effect.

I mean, I noticed when I've used it like 1.5 or 2 milligrams at times, like the effects last for like 24 to 48 hours sometimes. So if you wanted to cut that down into maybe like 250 micrograms or 500 micro grams and use it every day. I think you're going to get probably the same therapeutic effect, maybe not the exaggerating, you know, to the, the extent, honestly, we're not taking like 1.5 milligrams before. Um, sometimes The erection is overwhelming in the sense is like becomes uncomfortable to an extent.

So I know some people don't experience anything from PT 141. And to those people, I'm sorry, they don' get to reap the benefits from it. I m not sure why that is. But for me, it's not a bad thing, but it s also too. Uh, for anyone that's experienced it, you know, like it might not be the best thing, but I think for women too, uh, because it does help with women's libido, um, You could do that. So yeah, if you want to try it and also to some people get really nauseous from it.

Next question, this is a really good one. Someone said, I'm getting a gynecomastia surgery in the spring. Two questions, how far in advance should I start taking BPC and TB 500 optimized recovery? I would recommend like four weeks before. Then in terms of after the surgery, i would say at least like eight to 12 weeks, but really until you heal. So four week before and then like 8 to12 weeks after. Then the next question was, I'm also on turzapetide and retrutide. Any reason I would need to stop taking this prior to surgery?

Absolutely not. I think if anything, it's only going to help improve the healing. And if you're taking them post-healing, so you can definitely do that as well. So really good question. Someone says, please discuss the difference in efficacy of differing lyophilized peptides as supplied by manufacturers. That's kind of hard to say. I guess I can say that the difference between lyophilized and raw peptides is that lyrophilize have preservatives in there to specifically make them longer,

more stable and have a longer shelf life than raw peptides. Both in practice to me, I respond the same to lyophylized raw and peptide. And raw meaning not outside of a vial. raw peptides and some peptide is coming to vile. And when it's a raw pep that it actually doesn't look like there's anything in there because there is no preservative in their with the peptid. But if it comes as lyophilized, there a preservatives in ther to keep the peptide stable for a long shelf life. So you could get into like what Preservatives that are used is like mannitol bad, is it good?

Do some of these preservatives have lipopolysaccharides that could cause an inflammatory response? I think potentially the answer is yes to those. I, in my experience, and I've bought from a lot of research companies, have rarely have ever seen that. Again, I'm not saying people can't be doing bad stuff that is peptides, but I like 85 ish percent of the peptide market in the research world. They all kind of come from the same place. And most of those people aren't trying to sell you bad things. So I think you're going to be okay. Let's see.

Just scrolling through some of these are not worthy of being answered. Next one. This is a long one, so I want to break this down. But I think it's important, because I this would apply to a lot of people. I've recently gotten into the peptide field. Initially, not knowing a single thing, or that peptides even existed, and the more and more I have learned through work and your videos, the I'm interested in getting into peptids and I would love to increase my knowledge and learn again using them. Very good. Unfortunately, I'm not in a financial position for a one-on-one call.

Well, i'm actually taking my one on one calls away, so no one's going to be in financial positions because I am not going have them. But this is what I have these questions and answers for. So I was hoping if I could explain my situation, you could possibly give me more guidance on some peptides, which I should begin with also and possibly place me a place for me to begin to expand my knowledge on peptide to help me in the field that I am working in now. Word to the wise, if you ever send a question, and I'm not trying to be condescending here because I want to get through the rest of the question. Words to wise though, If you've ever sent me a questions, it would help if just put it in a chat GPT.

And even if have like a 700 word question put in chat gpt and say turn this text into an answerable question that someone can answer. So that when I read it, I can answer it. And again, not trying to be mean or judgmental with that. But sometimes I have to do that because people will send me like a thousand words. After I've read three times, still don't understand the question that people are asking from there. Anyway, continue on. I'm 24, about 235 pounds, between 25 and 30 percent body fat. I work out with weights three days a week and I've been for about two years when I began my journey.

The only way that I could lose weight was running two miles a day and eating once a and when i ate with salad and protein and i was losing weight rapidly and one day it just stopped so i began weight training to put on muscle to hopefully improve my weight loss journey Though I've been putting on muscle and becoming stronger, it is almost impossible for me to lose weight unless I'm an extreme calorie deficit. I was just wondering if I could get your opinion on what peptides to begin with, hopefully to help me lose weigh while also improving muscle building and possibly boosting my metabolism because I feel like it's practically non-existent. With the small research that I have done and watching majority of your videos for some reason, AOD 9604 stands out to me,

but at the same time I felt like there were better options out there and just wanted to ask somebody who knows way more about it than I do. would love if you could give me some pointers to get me started on my peptide journey and completely understand. If you cannot, I'm really going to learn more about peptides. So, and hopefully give the tools to better improve others' lives through the work that I do. Thank you for the question and the sincerity in the questions and I will do my best to give you a sincere answer. This is kind of a weird situation in a world at large right now because the man that wrote this to me God bless them, is probably like 70 to 80% of 24

year old men now. They're either like skinny fat or they're in a situation like this. And unfortunately they don't know any better because they haven't been taught any in the world. The existence of the word is predicated upon them not understanding this, so kudos to this guy for trying to change his life and reach out. to me and like get some answers and do what he can to research. So the problem here is that someone becomes overweight or they've been overweight their whole life. They try to do all these things and they work really, really really hard to those things like exercise, diet, live right,

all those and it just gets harder and harder, and they just want to give up. And like this guy, he's eating salad and protein and I'm eating one time a day and just nothing seems to be working. Well, you can manually do all those things and i'm not saying it's manually bad to Eat, right, train hard, not drink alcohol, do all those things, but you're going to hit a wall. And the reason is going come down to hormones. So I'll get to the peptides in a second. But when we look at hormone optimization, I would be willing to bet that this young man, 24 years old, has very low testosterone levels.

And if you have no testosterone levels, everything that you're doing from a weight loss perspective gets that much harder. So your doctor will never say, if your 24 years old to get on testosterone therapy, even as for the purpose of weight-loss, I would say immediately get onto testosterone-therapy. Immediately start taking desiccated thyroid because what's happening is your thyroid is stalling out and shutting down because you've been losing weight and you been trying to restrict, restrict. And you actually need the thyroid to help up-regulate your metabolism and help you burn calories more.

Um, and then I would begin to use, uh, potentially metformin or at least berberine to help with insulin sensitivity. I will continue lifting weights. And when you lift weights, you're going to put on more muscle from using the testosterone. So that would be the first thing. Then from there, I wouldn't look for a growth hormone peptide. In this case, probably test morellum. That would look to a microdose of a GLP one in this caserated trutide, wouldn' really worry about AOD right now, because even though that's more of like a fat loss peptides, it works better in the presence of someone that really knows what they're doing from a training perspective.

But I think you get the hormones addressed first. You come in with a growth hormone peptide like Tessamerelin and then Ritrutide of which you can all look up the doses on the peptides cheat sheet and everything. Um, you will be off into the races. Then you could even further add an SLUPP332, maybe even a mitochondrial peptide like MOTC or SS31 and boom, we'll be off to the races. So to this young man and to all the young men or people that you know that are struggling like this, even if you're older, SS 31, MOTC, SLUPP332, testosterone, renitrutide will knock it out.

But obviously I wouldn't do any of that until I have my hormones addressed, whether I'm a man or a woman, look into testosterone therapy, and look at your thyroid and obviously use an insulin sensitizer like metformin or berberine or even an SGLT2 that I am going to not talk about here. That'll be my response. So thank you for the thorough question. Hopefully it was a thorough answer for you out there and also hopefully it helped other people. Um, a little bit simple question, but important nonetheless. I purchased Sloop from Anabolic Anonymous, AKA AA, aka Amino Somewhere, which I cannot name because I think they don't like me saying that on my channel.

But basically it came in a bottle with a dropper top. How do I take this? So basically in that, It is a 30 milliliter bottle and each millilitre contains 100 micrograms. So what I would do is get a measurer measuring dropper that has one millitre and for every one milli liter, that's 100 micrograms, so start taking one millimeter first, see how you feel that'll be a hundred micro grams. I think you'll probably be better at 200 to 300 micrograms, which would be two to three millilliter. Very simple there.

Quick Google search will help you. Um, this is also a really good question. So appreciate and love your content. I'm a 46 year old that has gone from Clomid to Enclomophene to preserve, preserve my fertility while also raising my total testosterone. Actually feel a difference just on enclomorphene. The regular Clomet, uh, anastazol, gonadrolone, I originally was prescribed by a sketchy optimization clinic, had me feeling off. Well, no wonder you're taking an Astrazole. Way off, my wife and I are just starting to try for a little one. I know I can't be the only one going through this.

You and Jay's audience is mostly not young men. About to do a fertility test obviously, but barring any fertility issues, what do you think is the best fertility stack to help with motility, energy, sex drive, exercise performance? and recovery, old joints, et cetera. I eat very well, exercise hard, just lost 10 pounds using True Zapetide, which was awesome. Wanted a couple months, waiting a few months to try to run a True Tide. Currently on Sloop, Enclomaphene, Fertility Supplement Proxy, I don't know what that is, B12, D3, K2, Metformin, Nitric Oxide Booster,

Tadalafil, Fish Oil, Turmeric Sea, Magnesium Citrate, Sublingual, Hippomerelin, that's worthless, wouldn't use it. that I'm not use is doing anything, but I still buy from. Oh yeah. So he's saying, uh, he not using it because it doesn't do anything. But he bought it from a compounding pharmacy yet. They'll take your money. Um, so I want to take all the, a expensive crap, But we'll go to HGH when I finished that supply. It's a lot, probably poultry in comparison to what you take lately. I mean, it just depends. Thank you for what. You do is open my eyes.

No, post pandemic peptides, people's shrouds have been my mouth. you guys are doing good work. so thank you. I will say this, basically the question is fertility stack. All those things are okay. The enclomaphen is good. I would actually add in HCG and more importantly HMG. So off the top of my head, I'd probably start with 1000 IUs of HCGs. in addition to the Enclomaphene, three times per week is what I would do.

And then the HMG, I'd do like 25 to 75 IUs three time per weeks. So you'd probably want to land, excuse me, 25 Ius three-times-per-week for a total of 75 of HMG. So that's what I would add into the enclomaphen and also to injectable glutathione, I'd use like 500 milligrams once per week to add in with that. And that should help. Obviously, if you're using trisapatite and lost weight, that is going to help the GLP ones actually do really well for helping with fertility because obviously

it helps heal a lot of metabolic dysfunction. So only thing I would add into the anaclomaphene is HCG, 1000 I use three times per week, HMG 25 I used three time per weeks, and then injectable glutathione 500 milligrams once per a week. And that really should get you going. There's other stuff too, but I will try that first, see where it goes, where helps your semen go. And then also to, um, you could potentially add an injectable oil carnitine, 500 milligrams, three to four times a week. So that would be, uh, my fertility stack recommendation. I'll probably make a deep dive video on about that soon though.

Um, next question, is armor thyroid the same as desiccated thyroid? Yes, it is. Armor thyroid is just the name brand, kind of like, Viagra is the named brand for Sudenafil or Cialis is a name for brand Fertidolophil. so armor, thyroid. Yes. That is same. As desicated thyroid, Um, information on peptide blends. I get this question all the time. It's probably a time that I just answered again, specifically Tessamerelin 10 milligram and Impramilin 5 milligram. What's the recommended dosing?

Um it's up to you. Um I would say if you're going to use a blend, it is very simple. So if I had Tesamerelin 10 milligrams, Impromiline 5 milligrams I know that i want to basically 500 micrograms of Tessamerelin in conjunction with 250 micro grams of Ipamerelin. So if those were in the same vial, let's do math off the top of my head. I would add two milliliters of water to which I use 10 units of that water 500 micrograms of Tessamerelin and 250 micro grams of Ipamerelin.

Yes, I just did math right off the top of my head. So if I can do it, you can too use the peptide calculator. Uh, but that would be my recommendation dosing for that. Um, can you do an episode on which peptides work best to turn white fat into brown fat? I actually don't know off of the head, so I will research that, that is a good question. Next question. I'm 45 and was on the verge of getting a metformin prescription when I came across a study said that met formin use of men could possibly create birth

defects in their children. Not sure if I've done having kids yet. Just want to get your take on this as I do want start met forming. It's worthless. Did look at that study. What are the chances that diabetic men have birth effects in children? They're a lot higher than the normal person would just as a diabetic man taking met-formins. would probably have the same, you know, like a higher amount of birth defects than the average person would. So next question, 45 year old male, been on testosterone therapy for a few years, feeling great.

Been using peptides for about three months, microdose of RETTA three times per week, daily CJC, ipotessa, sloop, and five amino. And the results have been insane. I've been doing a variation of you and Jay's 30 days of shreds with mainly animal style diet and Martian great. Two questions. Thinking of switching over to HGH from CJC, Ipah, and Tessa. Can I take an HCH secreticot in the evening with HTH dosage to I use each morning? Yes, you can. And I think if you are really trying to lose fat, You definitely should. Or would that be a waste of time and instead just do one IU of HEHAm and one IUPm?

You could, I would say, for short term fat loss, probably the peptides are going to have a little bit more of a pronounced effect. For long term sustainability, i would use HEHam and PM. But you got to experiment and see what works for you. I've done both extensively and that's my take on it. He says, just want to run my testosterone levels by you. I feel amazing inside now, I'm muscular and lean. Currently my total T is 1475 and my free T 126, listen to your episode on TRT, your recommended free should be around 50 or 60 or up.

Wasn't sure if 12 6 sounds too high. If you don't have any side effects, no, I would say it's not too hi. I also don' know what the measurement of that is. It sounds like it is about right if your total T is 1475. So I'd say no. You know, like I really wouldn't worry about that. Yeah, he said thank you for all you do and I've learned some from you and feeling the best I ever had. The answer is no I wouldn' worry if all your other blood markers were fine. I don't care what the doctor says. So that's just my opinion, not telling you to do it.

Next one. Hands are up, you're doing well. I want to request a topic for your next video. Could you please cover out and mitigate the negative effects of the following protocol? Ipomerelin, 300 micrograms Monday to Friday. CJC with DAC, total weekly range of two milligrams split into two one milligram doses. Been following this cycle for eight weeks. Notice improvements in my workout muscle mass. I've been experiencing some side effects, pins and needles, starting with half with the recycle. Been waking up every morning with pins of needles in hands.

Water retention, I know significant water retention after using CJC a couple of times, which has progressively worsened over time. Injection site irritation. Despite rotating and injection sites, I'm experiencing irritation from CJC1295 with that causing a lump that lasts about three days with severe itching. I realize this is a common issue, but wonder if you had any advice on how to alleviate it. Context, a 30-year-old female, five feet too tall, weighing 52 kilograms and followed by a bounce on it and well hydrated.

Very simple response. Throw CJC 1295 with DAC in the trash. This is what happens when you take DAC. And I wanted to do this question because it's actually a good question, because people just buy this off a peptide site. DAC is terrible because of what it does. It extends the half life. And so in doing so, it causes water retention, the kind of like pins and needles feeling where your hands are falling asleep or whatever. Um, so yes, this is why I never recommend people use CJC with DAC. Get CJ C without DAC almost likely like guaranteed all those side effects are going to go away.

You may still have a little bit of injection site reaction, but either way you could just use it from Maryland and then just split the dose in a half and use that. you know, two times per day if you wanted to, but I would just throw the DAC, CJC with DAC in the trash. Next question. Can I prepare my morning injection to syringe the night before and keep in the refrigerator or night? Additionally, in a spirit of convenience and efficiency, can I prepared my injections for the week on a Sunday, similar to food prepping?

If not, what's the most amount of time anyone can prepare syringes beforehand? Thank you for your endless time and energy. Thank YOU for asking questions. Without you I'd be lost, and I know I'm speaking for thousands of others. Well, I appreciate you. That means a lot to me. Thank you for being kind and courteous. And the answer is yes, you can definitely do that. I probably wouldn't do it much longer than a week. You'd probably be okay, but you could definitely it like one week in a time in advance, as long as they're refrigerated. So as you like pull it out in the syringe and then put the Syringes back in refrigerator, You're completely fine to do.

It. and you Can prep your injections like you prep meals and be good to go. so you don't have to sit there and pull out injections every single morning when you want to take your peptides or every night when your peptides. So you actually can absolutely can. And, uh, I just probably wouldn't do it for more than two weeks. Cause sometimes if it sits in the, um, like with the rubber near the peptide too long, you can kind of get like, Um, Like thick and not as inject as well, because of being like next to the Rubber and the syringe. But if you it's there for a week, You're not going to really have that happen.

Good question. Um. Next question, Uh, Eight weeks on, eight weeks off. On the off time, can you introduce new peptides? For example, Eight Weeks on BPC, TB 500, Bremerelin, L-Carnitine. on the Off Time, SLU or other peptide? Yeah, absolutely. You can take peptidies when you're taking time off of other peptides. So you definitely can do that. Hi, I'm Jordan. I am a 47 year old female and focus my time in the gym on weightlifting. My muscles could lift, increase weight, but when I increase the weights, that can always end up with an annoyed knee, tennis elbow,

or some aggravated tendon involved in a lift. Regardless how I'll care for him with the form and then feel like my progress goes backwards, need to doing, uh, do need the, needing to back off and rest. Um, There's a lot there. I would say first, I don't know this person's hormonal status, testosterone therapy, 47 year old woman, most likely testosterone deficient at this point. Menopausal status or whatever, but as testosterone decreases, estrogen decreases you have no synovia or you much less good feeling in your connective tissue

because of estrogen being depleted. I know because I've had my estrogen crash multiple times in my life before and that's exactly how I feel. So I would say this is a hormonal issue first. And that would be my best response to that question. Reddit True Tide versus True Zap Tides, I actually have a video on that. Reddit true tide is great. I think there's appetite probably a little bit better for appetite suppression. Red True tide better fat loss. True zap tide a bit a better appetite suppresion. But you can use them both together if you really want to get good effects.

Um, peptides for winter for seasonal affective disorder, uh, to boost immune system and any others. It's 10 degrees Fahrenheit. I'm freezing in limited sunshine. Thanks. Uh, absolutely. Melanotan-1, thymus and alpha-one, um, definitely would be my go-to for those. So thimus alpha one definitely, I am using that right now in the winter time just to help with the immune. And then melanotane one, for the time that you're outside is going to enhance the absorption of the sunlight that your getting when you do get the limited sunlight you can.

Um, just blasting through. Hey, so in your episode on Ip and Rella, and you mentioned you were going to say what to use between epicycles, but I don't think you got around to it. Uh, was curious because I'm currently on the epiCJC and test it with my cycles about the end. I want to stay lean. Also, you mention you use it in the AM and Tessa in evening. Is this cycle simultaneous with HGH? Recycle HCH went off of the GH peptides. You can do all or either. So if you use ipamrelin, you can go to testimrelon.

You're still using a peptide that does that. They work a little bit differently. But I think if that's like all you had access to, You could do ipimrelin for eight weeks, then testimon for 8 weeks. And then take 8-weeks off if You wanted to. Or you could ipumrel, and then testsimon, for a week. Then human growth hormone. and then cycle back through. So really, there are infinite amounts of combinations you could have. My go-to thing would just be human growth hormone, regardless. I would do that regardless, like I mentioned earlier in the video, you can use a peptide in a morning and growth hormones at night,

or vice versa, growth in morning, and peptides at nights. It really just kind of depends on the goals, but you definitely do all, I think everyone should, just to see what works the best for them. Um, someone asked about GHK you injected. Is there a potential toxicity? Um I should, I'll probably do a longer video on this, but if I remember right, cause I started researching this in order to even be close to getting, um, close to like the upper limit of the recommended daily amount of copper in the body, you would have to inject like 55 milligrams of GHK.

And then it's usually excreted with the by like 12 to 16 hours mostly. So I think to breach getting close, to copper toxicity from GHk, You'd have be injecting like a whole bottle, because most bottles were 50 milligrams. To even get close it was like, 55 mg, and that's the limit for the daily recommended amount. Um, so again, that's not the toxic amount. It's just the upper end, uh, recommended upper limit. Um. And then, you know, it's out of the body. So if you're doing two milligrams to five milligrams daily, they're not even gonna come close to that and I wouldn't worry about it.

I'm so don't. Worry about that. People kind of, me know like, Oh my goodness. But. Someone asked me about Super Helios from Amino Asylum, which I think is like Clinbuterol, maybe Yohimbine. I just stay away from ClinButeril. If you use Albuterole, that's enough. if you have Sloop, That's Enough. You know, and even if he used Mirabegron, Which is a B3 agonist, Beta-3 Agonists, I don't really want to play around with that one because I know what it does to the heart rate.

So I know what injected albuterol feels like, and I don't really want to find out what injectable clenbuteral feels. So if you want and you're about that life, go for it, but I'm just not going to use it. There's one called Pyro that's injectible albuteril, I think it's yohimbine as well. And you inject like two milligrams of that. you, you feel it like no questions asked. So, um, I just don't like my heart rate being that high. I'm not like a super like stimulant type person. If you haven't figured from my personality, no, not a big like stimulate lover.

Um, go figure. Uh, how important is cycling peptides and which ones have the most risk of desensitization? Um I think it's, it's important relevant to your goals. So like, what is more dangerous? If the answer of like whatever, if you ask, is it more for me to cycle off the peptide or to not have the peptide? And it is dangerous or more damaging to have not the Peptide, then probably stay on the Peptide until whatever is damaging becomes not damaging.

To you. so like ask myself, Is it damaging more to stay this Peptid? and have to increase the dose, there's more damaging to be away from the peptide because of the results I'm getting. Meaning that I am like severely overweight or I have a severe injury. I think that would be the answer. And if it's like, Hey, okay. Like I need to cycle off my redhead trutide, like okay, what's dangerous? just take the time off the Reddit True Tide, right? But if I'm 39% body fat, I probably need to stay on Reddit true tide and figure out a way to maximize the benefits over the longterm.

And then they just said HGH. I do have a comprehensive video on HTH if you want to check that out. But point being is like, what's more important, cycling off peptides or becoming desensitized to them? Well, it's important to not be in a situation that's harmful to your body for the longer term. If that means you have to increase the dose on the peptide to heal an injury or to lose fat then I would do that. But if it doesn't mean that, then I would probably cycle off the peptide and use another one in between or just cycle it off immediately. Someone asked about PNC27. I'll do a comprehensive video on PnC 27. Just got to be careful with that one because it's talking about the C word and tumors and stuff.

Are peptides and reginistrate appropriate for post-menopausal women? They 1,000% are, but every post menoposal woman should be using hormone replacement therapy. I think that is like the one case where that has no questions asked. Post-manopause women should on testosterone, estradiol, and progesterone. No questions ask. Don't want to hear it. No questions asked. If you're looking for peptides as a post-menopausal woman, you better be on testosterone. That's one of those things. Like if we look at like the one group of society that's so like ostracized and, uh, gaslighted by the medical establishment,

it is menopause on postmen, a woman women because uh, of the fact that they don't have hormones. So like nothing in your body is going to work right. No peptides are going work, right? If you don' have hormones in our body. It's really sad that that's not like frontline care for a woman after this. She goes to menopause to give her testosterone and give estrogen and progesterone. Kind of infuriates me. Um, that, you know, like people don understand this and you have all these people with like degrees, out the wazoo that don''t understand it. All right, so this is a good question.

How should I start a peptide and optimization plan? For instance, how do I choose my priorities? And then what do work on muscle gain, cognitive, longevity, immunity, joint health, sleep optimization, sexual function? How many things can be treated simultaneously? and what would a game plan look like starting a Peptide rookie all the way through a master biohacker? Well, that would be like really like a whole course that I would have to do that'd be hours and hours long. And then how does one find a list of peptide and optimization physicians? Yeah, that's good luck doing that.

But I would say like the first thing is like, what is your bleeding neck problem? So if you look at someone's life, are they in pain? Are they suffering greatly? Well, how can I address that with peptides? Okay, let's get that through and then like kind of move up like Maslow's hierarchy of needs of like helping me. Like the highest is self-actualization. ultimately like that's the master biohacker, right? They're just using peptides to amplify and improve every area of your life. So I would say, um, the first thing like, are you fat?

For most people, it's gonna be like are fat. Okay, yes. Let's get that under control and then get everything working from there. Um, but it might be, or you injured. Well, let's give the injury under because injury would be uh, you know, more important than fat loss. So get that in control and then work on the next. Um, it really kind of depends on situation, but that'd be my goal was like, think of like the bleeding neck problem, address that first and kind move up Maslow's hierarchy of needs. And it's like okay, like I want my eighth app to show more, because I have a six pack one on my eight app.

Okay, now we can address with peptides or whatever. That would be how you move. Next one, do you take NMN and why is there longevity space in people that take M&M to boost NAD instead of just taking Nad? One, because you can take in NmN orally and NAd to be effective has to injected. So that's why people do it because they can sell a supplement that you need to take oraly and most people don't want to inject stuff. That's the first reason. But I think it would behoove you if you are supplementing with an Nd to use Nmn as well because it helps as a precursor to how your body uses it.

It doesn't hurt to But a lot of people are like, oh, just buy this. You don't need to take an AD and inject it. And yes, in theory, being a precursor, it would help theoretically raise an ID levels, but I think you would use them together if you wanted to maximize it, so it looks like that is it for the questions. So a really good bunch of questions, looks we've been going for almost 40 minutes now. Um, hopefully that was helpful to you guys. And again, all I'll say in closing out this one is first of all, thank you because I have the best audience. I don't know any YouTuber in the world. There's some out there if they get the quality of the question.

So thank guys, um, and remember to, to make these Q and a videos good, uh, leave a question in these suggestion box, which is in a link, a description at every video. Uh, again. Thank you so much. Um I dunno exactly when this will air, but if it's around Christmas getting close to Christmas, I hope you have some time to spend. with your loved ones and family over the holidays and really think about what's important. I know I will be, and I hope you do the same. So appreciate you guys, much love. As always, my heart overflows with gratitude to have any sort of connection or interaction with you and to know that we're all on this journey together.

Appreciate you, guys. And I'll see you in the next one. Peace.