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Peptide Q&A · November 2024

2026-03-29 · 46:16 · 7 min read

It's Q&A time. I sat down and pulled together about 35 questions from the submission box this month, so this is a long one. Here's the rapid-fire round on travel, GLP-1s, HGH, peptides for women, and a bunch more.

Traveling with peptides

I've actually done all three scenarios in the last few months. Road trip, domestic flight, international flight.

For a road trip, I throw everything in an insulin cooler with frozen ice packs. Put that in a Yeti style cooler. We did this last weekend going to the North Carolina mountains with our dogs (whose raw food also has to stay cold). Easily good for 10 to 15 hours.

For domestic flights, put your insulin cooler with frozen ice packs in your checked bag. Not illegal in your carry-on, but I'd rather not have a TSA agent see needles and start asking questions.

For international travel, same setup in checked luggage. If customs opens it and asks, just say it's medication for personal use. Peptides are not illegal. Needles can go outside the cooler since they don't need to stay cold.

My rule, don't carry peptides through TSA in your carry-on. Not worth the headache.

"I'm taking 20 units of HGH"

I get this a lot, so let me clear it up.

Saying you take 20 units of HGH is like telling me you drink three cups of Kool-Aid. I have no idea what that means. It depends entirely on how much water you mixed into the vial.

HGH is measured in IUs or milligrams. Always reference dosing that way. If you tell me units, I literally cannot help you.

Coming off semaglutide and gaining fat on HGH

Someone said they came off sema, started HGH, and gained three pounds of fat in six weeks despite getting stronger.

A lot is going on here, but my first suspect is the thyroid.

When you lose weight fast on a GLP-1, your thyroid downregulates. This happens whether you used a GLP-1 or not. Lose weight faster than 1 to 2 pounds per week and your thyroid responds by slowing down.

So if you're coming off a GLP-1 and going on HGH, here's what I'd check.

Testosterone (man or woman, doesn't matter). Thyroid (consider desiccated thyroid even if labs look normal). Insulin signaling (metformin can help).

Also worth knowing, if it's underground HGH instead of pharmaceutical, results vary a lot. And if you put on three pounds of fat but added 10 pounds of muscle, that's a win. Muscle is your metabolic currency for life.

Peptides for acne

Acne has been a thing for me on and off, and water quality plays a bigger role than people realize. My city water supply is one of the more contaminated in the country. I noticed less skin irritation when I filter my shower water.

For peptides, my five for acne would be LL-37, Thymosin Alpha-1, KPV, BPC-157, and TB-500. That looks a lot like an autoimmune stack, because acne is often autoimmune in nature.

Estrogen and HGH dosing

If you're on estrogen, you don't need to up your HGH. If anything, optimized estrogen helps you get more out of your HGH because it improves IGF-1 synthesis.

This applies to men too. Plenty of guys on testosterone use aromatase inhibitors and crash their estrogen, then add HGH and wonder why it's not working. They're wasting it. Aromatase inhibitors are poison for therapeutic testosterone users in my opinion.

Sermorelin and cycling GH peptides

Sermorelin, I just don't think it's good. Wouldn't use it.

People ask if they can cycle onto a different GH peptide while off another. Not really. Take 4 to 8 weeks fully off if you plan to cycle back on.

Better play, run GH peptides for 8 weeks, then switch to actual HGH for 8 weeks, then back to GH peptides. Way better response than rotating GH peptides.

Also, ModGRF 1-29 and CJC with no DAC are the same thing. So if you "switched" between them, you took the same peptide.

Liraglutide vs semaglutide

Liraglutide has a much shorter half life than semaglutide. Same mechanism, just shorter duration. Only use case I'd consider, short term appetite suppression for 24 to 48 hours. Not as powerful and you'd have to dose daily.

Tesofensine cycling

I prefer 60 days on, 6 days off, at 250 mcg per day. You can also dose every other day and get the same effect because the half life is long.

It's amazing for focus and cognition. Less so for appetite suppression in my experience. Studies have run 18 to 24 months without withdrawal issues, so long term use is fine if you need it for cognitive support.

Don't go over 250 mcg. People take 500 and get the same benefit with more side effects.

BPC-157 and TB-500: site of injury or belly?

Site of injury, every time. For elbow tendonitis, pinch the skin around the elbow and inject right there with an insulin needle. I'd even add PEG-MGF to the syringe.

Belly injection works, but you're getting maybe 60% of the effect compared to 100% at the injury site.

Stack to use during a fast

If you're fasting on weekends, swap 5-amino-1MQ for SLU-PP-332. The 5-amino is fat soluble, so it works best with food. SLU is better in a fasted state.

AOD, Reta microdoses, and CJC/Ipamorelin are all fine fasted. Add 10 mg of Cardarine and maybe some albuterol and you're off to the races.

Peptides for glowy skin

GHK-Cu, SNAP-8, and for acne specifically Thymosin Alpha-1, KPV, and LL-37.

Peptides to avoid if you want to stay lean and only build muscle

Honestly, none. The answer is hormone optimization.

Lean people, especially lean women, often have suboptimal estradiol because they aromatize less testosterone. There's a sweet spot of estrogen that helps both fat loss and muscle growth. Estrogen is crucial for muscle.

If you're prepping for a photo shoot, drop HGH or GH peptides for a week or two since they can cause water retention.

Retatrutide for weight and sugar management

0.5 mg three times per week. Done.

Peptides for oxygen uptake

Anything that promotes angiogenesis. BPC-157, TB-500, VIP for the lungs. ARA-290 if I'm remembering right is a modified EPO without the side effects, helps with chronic pain and oxygenation. Mitochondrial peptides like MOTS-c and SS-31 also help.

How to come off high doses of tirzepatide

This is one I haven't talked about much publicly.

If you're stalled at 15 mg of tirzepatide, don't just stop. Wind down 10 to 20% per week over about 4 weeks. Add low dose naltrexone starting at 0.5 mg and titrating up to around 3 mg.

After winding down, take 2 to 4 weeks fully off, still using LDN. Then reintroduce at a lower dose. This gives you a cellular reset and a better response when you go back on.

If you're at very high doses, your diet and lifestyle probably need work too. Fix those during the wind down.

MK-677 for a 15 year old wanting to gain weight

I won't give protocols for kids on YouTube. But generally, MK-677 wrecks blood sugar and there are better options. A growth hormone peptide or actual growth hormone would be a better path than MK.

TUDCA and blood sugar

Avoid MK-677, it makes blood sugar worse. GLP-1s in my experience modulate blood sugar rather than crash it. Same with metformin alongside a GLP-1. I haven't seen people crash low.

Peptides for postmenopausal women

The answer is testosterone. Plus estradiol and progesterone depending on labs.

I get a lot of questions about menopause and rightfully so. Hormone manipulation can wreck you when levels aren't optimized. Sure, you can use Kisspeptin or a GH peptide, but I'm never going to tell you a peptide is the answer to menopause. Hormone optimization is.

Peptides for women in general

For women's content, go check out my fiance Taylor Reed Coaching on YouTube. Best women's peptide videos out there, point blank. I'll never have a menstrual cycle or bear children. She speaks to that directly.

I do have a testosterone for women video coming.

Oxytocin not working at 50 mcg

Bump it to 150 to 200 mcg. I use 200 mcg regularly. I recommend people start at 50 because it can cause flushing and bowel movements, but if you feel nothing, go higher.

For a postmenopausal woman, also add PT-141, make sure testosterone is dialed in, and consider estrogen for libido.

CMAX response time

Depends on dosing. Most people see 100 to 300 mcg recommended. Go up to 1 mg and you'll usually notice it. I prefer the N-Acetyl semax amidate version.

Mazdutide vs retatrutide

Mazdutide is a GLP-1 and glucagon agonist, so it's like retatrutide without the GIP. Two mechanisms instead of three. Better than semaglutide probably, but no reason to pick it over retatrutide.

Cycling off CJC with no DAC at 47

Jump straight to HGH. Then you can cycle between GH peptides and HGH. Eventually most people just end up on HGH for good.

Raw peptide powder

Don't. I don't measure out raw powder. I get the question a lot because raw is cheaper, but unless you're an advanced chemist with proper equipment, it's not worth it. I have suppliers I trust and I'd rather pay for that.

My take

These Q&As are good because the questions are good. If you want yours answered next month, drop it in the question box link in the description, or come hang out in Fully Optimized Health where we do weekly live Q&As.

Enjoy the holidays with your family. All this peptide stuff exists so we can be healthier, love more, and share that love with the people around us. That's the whole point.

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Full transcript click any paragraph to jump video

Hey everybody, this is Hunter Williams. I hope you were doing amazing wherever you are in the world. Today I am bringing you a much needed Q&A video. So I've been pretty busy this month, but I finally sat down and took time to compile all the questions that I received into the question box this months. When this video is released, it's probably going to be, I think, Black Friday is when I'm going have this one released. Hopefully this some entertainment and education for you over the holiday weekend, whether you're traveling or enjoying time with your family and just need

a break from your families. So what I'm going to do in this one, like all my other Q and A videos, I am not going share my screen, but I have all the questions written down. I was just going go one by one. Hopefully I will get all through all of them. In this video I've got like 35 questions for this, so we'll see how it goes. But just a reminder for anyone watching this. If you want your question answered by me and I pretty much want a guaranteed way to get it answered. Do one of two things. You can look at the link in the description that is the video topic slash question or suggestion box that you can go in and submit a question to.

And that will go directly to a folder that I have that. I put all these questions in, or if you would like to message me or have your question answered live on a video, you could head over to fully optimized health. That is private membership group. And that is where we do weekly live Q&As where you can ask me questions any time and have them answered. Or you could also message me inside of that group to get a response. So what I'm going to do is pull these up. And we're just going rock and roll rapid fire through the Q and A. Let's get to it.

I was really impressed the last few weeks since I did the first Q & A video with the ones I had. Um, the first one, I actually don't know the answer to. I'm going to do some, uh, more research on this one. But I did a video on the last few weeks about human and, and someone asked me, have I ever heard of Cola villain, which is similar to human. Uh, but I will look into that and potentially experiment on myself and do a new video. So thank you for sending that to me.

And a lot of times too, people don' send me questions. They actually will send. Um. things that they came across. And that's actually, you know, one of the ways that I do my research is I just get all this feedback from the amazing people in my audience and do that. So again, I can't thank you guys enough. I have the best audience in the world. Next question, how to home brew injectable eucarnitine. I have done this in the past. I likely will not make a video on how to home brew injectable l-carnitine. There are other good videos out there on YouTube.

Actually learned how do that from watching a YouTube video myself. It's great if you want to save money, but fortunately I don't have to worry about spending an extra hundred or two hundred bucks every couple of months on injectable L-carnitine. There's plenty of good websites out there that can sell you injectible L carnitin. I will not mention those on my YouTube channel. And if you ask in the comments, I'll delete the comment and ban it or ban you on YouTube because that is how channels get deleted.

Knowing what I know now, that's probably how my old channel got deleted So I'm not going to do that. There's other videos on YouTube where they talk about that, but I don't do it anymore. It's pretty simple. You would just end up buying L-Quarantene powder and you've got to use bacteriostatic water. And you basically have to filter the powder through a syringe filter and then put it into the water and mix it. I've done it a bunch of times myself. If you're resourceful enough to ask the question, there are other YouTube videos that I learned from.

But now I just buy it from other places because it is a little time consuming, but if you want to save the money, it's definitely worth it. Next question, someone said, I think a great topic to cover, especially with the holidays coming up, would be traveling with peptides, traveling by car, by plane, United States, and then by plain internationally. I know for me, meaning this person I traveled to Europe every summer in the past I've just left peptides behind because I wasn't sure how that would work. I mentioned this before but this is a good question just rehash in light of the holidays.

So I personally I'll give you how I do this because i've actually done all three of these things within the last few months. Last weekend, I actually traveled on a road trip to the mountains here in North Carolina. It was amazing. Me and Taylor went hiking and it was a phenomenal experience. But what we did with our peptides is I put everything in an insulin cooler and I had the packs frozen, the ice packs, frozen. Put that in there. And then we brought a cooler with us because we bought our dogs with this and their dog food has to stay frozen because they eat raw dog foods that's frozen

And we put all of that in basically just like a Yeti cooler. We had a big one, but you can get like, a small one. So you could do that. And then if you're driving for like 10, 15 hours, it should stay cold enough for you at least to like make it to a refrigerator or a hotel or wherever you were going. That's easy by car. If you are going by plane in the USA, I personally would put all of these in my check bag. I would not put it in a carry-on bag just because, again, not illegal, but you don't want to run into any issues with people at TSA that may see needles or anything like that in there.

So I will just put my insulin cooler with my frozen ice packs in checkbag, put in in and you'll be good to go. You just in the check and then go there As far as international goes, you would really do the same thing. You may just have to be aware that at customs, wherever you go, if they open your bags and look at your bag when you're coming in, even if it's a checked bag, because some countries do that in customs. They may ask you what it is and you just tell them it was medication for personal use and just told them is peptides. Again, it not anything illegal. But again, just put it in an insulin cooler with frozen ice packs in there.

And you can put your needles outside of that, because obviously the needles won't have to stay refrigerated, but you just put those in there. So again, very easy to do. But my recommendation, generally speaking, is to not put it on your carry-on bag and go through TSA. I've heard plenty of people say they've done that with no issues, I just don't want to get hung up or whatever in T.S.A. and have deal with that. Good question though, in light of the holidays. So next question is, these are some good ones this month. I'm coming off some agglutide and I've just started taking 20 units of HGH.

So let me stop right there. I don't know what 20 units of HGH means. That would be like telling me you're drinking three cups of Kool-Aid.I don' know how many calories that is. It could be a hundred calories, it could 300 calories. Could be five calories depending on how much you use. So I dont know. What that means when you say you've taken 20 Units of HDH. You either would have to say, you are taking a certain milligram amount or a Certain IU amount of hgh because that's how Hgh is measured. You can use either one. Typically we're going to refer to HGH and IU. So I don't know how much it is.

My guess is it would be somewhere between one to two IUs. I dont know though. If you ever send me questions like that, understand that I can't help you if you're saying I'm drinking certain numbers of cups of Kool-Aid. BPC, I'm thinking 20 units of HGH. I don't know how much that actually is because it can be different depending on how water was mixed with it. Just so you guys know that and learn that, you'd never reference how you're taking something in units.

You never do that. Um, carrying on it's been six weeks and I've gained three pounds, uh, that the in-body says is fat despite being much stronger. I do feel bulkier in general, especially in the belly and there's more fat to pinch on my back and belly. Am I doing something wrong? Should I be stacking something to prevent fat gain while coming off SEMA? There's a lot to unpack there. First, let's say, yes, if you're taking HGH, you typically will be slightly more bloated, retain slightly water, and in that process you may gain more fat.

Now, I don't know if this is pharmaceutical HTH versus underground generic HGH. In the case of underground generic HGH, I would say that's very plausible. If you're taking one to two IUs, and I don't know how much in this case, maybe they're takin' eight Ius and they don' know it. But I'd say if it's pharmaceutical HTH, you are definitely going to get benefits and if its at the right dose you probably should be losing fat. all things being equal. Now, what I don't know is if a person is hormonally optimized, meaning that it's great to take HGH, it is great take pharmaceutical HTH.

However, I would want to know, are you using therapeutic testosterone, whether it a man or a woman? I think that would be crucial. And then also too, you need to optimize your thyroid. What happens a lot of times is people will come off of a GLP-1 And they've usually lost weight, and they usually lose weight pretty fast when they come off a GLP-1. And in the process of losing weight fast, whether or not we have a glp-one. So this can happen whether you have GLp one or whether don't. When you lose weigh rapidly, the thyroid tends to down regulate.

I won't go into that on this video. Probably should make a video about that separately about why when you loose weight the thyroids down regulates. So my opinion of what is happening here is this person lost a lot of weight or lost weight fast, and now they're taking HGH. They're obviously doing resistance training, it sounds like, because they are getting stronger. but they're saying there's more fat. And in my opinion, my first suspect would be the thyroid. Because if you're not optimizing the thyroids with desiccated thyroid, and you lost weight fast, whether or not you used a GLP-1,

I don't care if did or didn't, if lost weigh fast faster than you normally would, or faster like one to two pounds a week, which typically people are doing, with a glp-one, you are going to likely I wouldn't say like have a rebound weight gain, but you will notice that for the same amount of calories that you're eating versus the amount exercise you are doing, you probably are gaining a little bit of weight. Now, I don't think essentially it's such a bad thing if you put on muscle in the process. So if your putting on three pounds of fat but your adding 10 pounds muscle, well for me that would be well worth it because the muscle is my metabolic

currency for long term for my life, meaning it is going to help my metabolism for a long run. So there's a lot going on there, but I would say if you are coming off of a GLP-1, typically you have lost weight. Look at testosterone levels, look at the thyroid. And then also obviously too, we want to look insulin signaling, so I have to use something like metformin to ensure. So this is actually a good idea because I'll probably do a whole video of like what to do when you come off a GOP one to make sure that you don't gain fat. So thank you for that question, but I would say look at testosterone, look of the thyroid, and you're likely going to want to supplement both of those

pathways to make sure that she sustained the momentum you had with fat loss, that can also kind of work to rebuild muscle in the process because you are going back into a caloric surplus to build muscle. Next one, simple question. Peptides for acne. I will say right off the bat, first, if you have some, let me know. No, but acne is something that I've struggled with more or less for long periods of my life. And usually don't have acne because of a peptide deficiency.

But I'll say there are certain ones. So LL37, great one for acne, thymus and alpha 1, BPC157, TB500, I would probably even look at something like a KPV that helps with gut health and suppressing inflammation that will ultimately help with skin health because KPB does help skin. So if I had five right off the bat, it would be LL 37, diamonds and alpha one, KP, BPC 157 and TB 500. And that looks very similar to like an autoimmune

peptide stack. And more or less, a lot of times acne is auto immune. One thing that I have been experimenting with, and we'll see how this goes, I've noticed I tend to get more acne when I am home versus when i travel. When I'm traveling, typically the water supply is different from when at home. And I looked up the city water supply that I have is one of the more contaminated in the country. Go figure. And, I've noticed when I filtered water for my shower that it tends to cause less irritation on the skin. So that's something I'll probably report more back on, but I think also too, if you're dealing with that, look at the quality of water that you are taking

a shower with and see where that leads you. Next question, if I'm on estrogen, do I need to up the dose for HGH? I read mixed messages online. Currently taking four IUs. Thanks. I would say not particularly. Um, If anything would probably be the other way around, meaning that again, this is bro myth lore. Not saying this rooted in any study that I've seen or anything like that, but. Optimized estrogen levels lead to optimal synthesis of IGF-1 out of the HGH that you're taking, meaning that if you are taking HCH but your estrogen has crashed,

it's probably going to have much less of an effect of the desired effect that you want from HGH. So I would say if anything, if you are taking estrogen, make sure that your levels are optimized to get the most out of your 4IU. But I don't think increasing the amount of growth hormone you're taking would necessarily do anything in the presence of low estrogen levels, if that makes sense. So I would say no need to up the dosing.

But if you're on estrogen, probably you had a deficiency at some point. I'd say to look at making sure your estrogen level are optimized to get the most out of your HGH. What's funny is I don't know if this person's a man or a woman. My guess is they would be a women, but I think men could also benefit from supplementing with estrogen. You have a lot of men that are on testosterone therapy plus an aromatase inhibitor, and they don't need an Aromatases inhibitors because they're poison, especially for therapeutic testosterone users. And so they use testosterone, they used aromates inhibiters, but then they've used growth hormone and don t realize that they re probably wasting a lot

of their growth hormones because their suppressing estrogen to such low levels. So just my opinion, I know there's like lots of debate on that, me personally, in my personal experience, When I've had crash estrogen versus optimized estrogen, the growth hormone seems to work better. And that's just my feedback. So next question, any opinion on seromerelin? Also, what is the difference between ModGRF1 and I think they mean Modgrf129 and CJC? I cycled off CJT and apamereline and started ModGrf1 I'm trying to stay as lean as I was on the other peptides.

Thanks for your content. It's the best. Well, thank you. Um, my opinion of seramarylene, I just don't think it's very good at all. So I wouldn't use it. I would be more inclined to just cycle off those completely. and then cycle back on them. And then there's other things you can take in the process of cycling off. You know, people all the time say, like, can I cycle onto other GH peptides while I'm off of other ones? I don't think so. I mean, you may get like a decent response from the other ones, but I think you really do want to take at least four to eight weeks off of the GH peptides,

assuming that you're going back on the change peptide in the future. So I would just say cycle off. Now, if you wanted to use GH Peptides for like eight and then cycle to growth hormone for eight, weeks, and they go back to GH I think you're going to have a much, much better response to that than you would cycling GH peptides in between the off of whatever you are taking. So in relation, they did ask, what's the difference between Modgrf-01 and CJC? So ModGrf129 is CJc with NODAC, and then CJs with DAC, I thing, is something else.

But ModGRf 129, it is the same as CJ with NoDac. So unless I'm reading this wrong for the person, they were taking the same thing. So again, I am just going off of memory here, so there's a lot of letters and stuff there. If I misspoke on that, don't crucify me. But ultimately, the moral of the story is if you're just using GH peptides, it would take eight weeks off in between and then potentially use a GLP-1 or

something else in between if you're worried about losing your gains. But for me personally, I would choose HGH in-between. You don't have to worry about it. And I will just use HTH, period, assuming you can afford it Um, next question, Lyric Glutide, basic overview as well compared to other GLP ones. So if I'm going off of memory here, I believe Lyra glutide. Um I just don't think it's as effective as even Cima glutides. I also believe it has a much shorter half life.

so I have heard of people using it as a short term intervention to suppress appetite, meaning that you could take it on one day and really suppress your appetite for like the next 24 to 48 hours. and then it goes away. So I believe that it works the same as semaglutide. It just has a much shorter half-life, meaning that's out of your system. the effects of it, you would have to take it every day, pretty much. But you could use it. I would say like the only use case I'd have for it now is to have a short-term intervention to suppressing appetite and getting the affects of the GLP-1,

which a lot of times is not the weight loss, it's more just the appetite suppression. So that's my thought on it but I probably won't do a comprehensive video on that just because it is relative to what we have access to out there. It's just not as powerful and not beneficial. Next question, women going through perimenopause and on menopausal, which peptide do you use to optimize health and prevent weight gain? Testosterone. So this is another one of those questions that someone says, I have, what's the peptides for this? I would say testosterone.

And depending on your hormone levels, estradiol and progesterone from a woman in menopsis. I get so many questions around women in Menopas and rightfully so because It's something, assuming they live long enough, every woman deals with, and also too, it can be very difficult to deal with. And I know from hormone manipulation in the past in my life, experimenting with all this stuff, that you can a wreck when your hormones are not optimized. So that would be my first thing. Sure, you could use KissPeptin. You can use a growth hormone peptide to build muscle and burn fat.

But I'm never going to sit here and tell you that the answer to menopause or perimenopaus is a peptide because it's not it. It's hormone optimization. Um, so I would look into that and, uh, stay tuned for a video I have coming up, a four hormone observation for women. Next question, tesofensine is amazing. Thank you for recommending it. Do I need to cycle it? Would it create receptors resistance or can I just keep going? So I personally prefer to use teso-fensin 60 days on and six days off. I actually haven't used it in probably like three months.

And I will say it's one of those ones at 250 micrograms per day, or even if you're taking it every other day which you can definitely do and really get the same effects because it has long half-life. I think it works amazing. It works. Amazing for focus and cognition. I don't get so much appetite suppression from it, but I will say that. You could use it long-term. I just don't know that you would need to. Meaning that if your goal is fat loss and appetite suppression, there's so many better things out there. If your goals is cognitive enhancement, you could it for the long term.

But they've definitely done studies, I think up to like 18 or 24 months where people haven't come off and they stop it and there is no sort of like bad effects or withdrawal effects, or anything like that. I think you'd be fine to stay on it.

I would say for someone that's new, cycle on, and cycle off, you're just going to get a better response, I think, for the long haul. But if you need it, if need for focus or wakefulness or something like that, because it definitely helps with that. I would say use as needed, and I wouldn't be so worried about it in terms of just creating receptor resistance. But again, that's a lower dose. I don't recommend going over 250 micrograms. A lot of people take 500 micro grams, but I just think you get the same benefit. 250 is to do a 500 without any of the perceived side effects.

Next question, the BPC 157 TB 500 combo, should it be injected into the area of the injury or just subcutaneously into belly fat? been researching. I'm getting a 50-50 split on the answer. For context, I have tendonitis in my elbow from lifting and also lower back chronic pain. Thank you. So in that case of tendonitis and lower-back pain, you definitely want to inject an injury site.I would even throw in some PEG, MGF into that syringe with the BPC and TP 500 and do it. If you inject it into your belly, it's not that it won't help. but I would say it's probably like, you'll get 60% of the effect instead of a hundred percent of effect if you inject an injury site.

So a good question. And like for instance, when you're injecting the elbow, I'll try to show you this. Like you just want to like pinch the skin there. I don't have like a ton of fat on my elbow. But like if your watching the video, can see you would just like kind of pinch right there and then inject in that little pinch spot. With an insulin needle, very easy to do. Next question, what stack do you recommend to use during a fast? Currently I fast during the weekend and I use five amino AOD and one of my Reta TruTide microdoses during week at CJC, Ipotest,

Mirelin, RETA Tru Tide. Also how to sloop work into this mix and it's a good add to the stack. Definitely would be a good add to this stack. To that point, you could use 5-amino during a fast, but it is fat soluble, so I particularly don't like to use it during fasts for that reason, meaning that it works best in the presence of fat, which obviously if you're ingesting fat it would break your fast. So I would replace the 5 amino with the sloop in that. And AOD is fine, red trutide's fine in a microdose.

And CJC, IPA, Testimonella, and red-trutides, those are all fine to do. In a fasted state, but if you're eating on an eating day, it's find. But over the weekend, I would say sloop. I will throw in maybe some albuterol, maybe a little bit of carderine, 10 milligrams of carterine. You'll be off to the races during a Fast, especially if your doing it over a weekend. done before. So I would just change the five amino to sloop and add in 10 milligrams of carterine and you'll be off to the races.

Next question, what are the best peptides for beautiful glowy skin, reducing wrinkles and acne? Specifically, I would say GHKCU, SNAP8, and especially for like the acne, maybe like Thymus and Alpha-1, KPV and LL-37, because that's gonna help with the skin as well. So that what you can do. You can obviously look up all the doses that I have recommended to that. Easy enough there and kind of related to one of the other questions we had. Next one is which peptides to avoid when you want to stay very lean and only grow muscle?

Female, 38, fashion model physique. Doing La Grie for weight training. I'm not familiar with that. Two times a week. Plus cycling and hiking sessions, one to two times week in addition. Peptides that I would avoid. Trying to stay lean and only grow muscle. Don't think there's anything specifically I'd avoid, honestly, this is probably not the answer. you guys or this person wants to hear, but again, it goes back to hormone optimization. So someone, if they have a fashion model physique and they're very lean and there are trying to put on muscle, a lot of that's going to come down to hormonal

optimization and also to, If you're using an HGH peptide, which I would recommend for that. A lot times men and women that are super lean, their estradiol levels are not optimized because they aromatize less of the testosterone into estrogen and their Thus they have less circulating estradiol in their body, which a lot of times can relate to fat loss and actually inhibit fat. And that sounds crazy because a lotta people suppress estrogen to lose fat, but if you look at it, there's actually like a sweet spot of estrogen that would be beneficial to losing fat and also growing muscle.

Estrogen is crucial for muscle growth. So I would look the hormones first if I'm doing this. Peptides to avoid though, I don't think there is any that I specifically avoid. If you are trying to stay very lean and in Bodo shoot shape, I wouldn't use HGH or an HGA peptide just because that will create a little bit more water retention, even though it will help you gain muscle in the process. So maybe cut that out a week or two if you are a fashion model and looking to do that, but have a photo shoot. Next question, how to use red trutide for weight and sugar management.

It's pretty simple, 0.5 milligrams three times per week. Boom, there you go. Easy enough. Hydrate the dose as needed. Next question, are there peptides that might help directly slash indirectly increase oxygen uptake in the bloodstream? So anything creating angiogenesis would benefit such as BPC, TB 500, and there are other options. There definitely are. So I would start with those because obviously those help with oxygen outtake. Um, there's another one called VIP. I don't know specifically it helps with the oxygen take, but it does help the lungs, which will also be beneficial to that.

Some research companies sell EPO, which is what Lance Armstrong was using to perform better in the cycling races. I'm not a fan of that. You know, I would say probably ARA-292 would be beneficial for that purpose as well. If I'm not mistaken, and don't quote me on this, ARI-290 is a modification of EPO without any of the side effects that helps one with chronic pain,

but then also two with like oxygenation of blood. And then I think a mitochondrial peptide like MOTC or SS-31 would really beneficial too. So those would what I'd add in. Next question, we'd love to see more information on bioregulators, specifically the synthetic versions that are being used and the three stacks that were done two or three times per year. Yeah, so I actually don't. I will say stay tuned for this because I'm going to be doing a lot more experimentation. The problem with many bioregulators is just sourcing.

In a large scale right now, it's hard to source. So I would do much more educational content on this in the future once I have them and can accurately and in a detailed manner give you my feedback. So stay tuned for that, but I don't want to speak too soon before I know. I could, I just want everything together before. I'm making sure someone does not take too much copper peptides, calculating to ensure that they don't overdose or have copper toxicity. Can you explain the math on this?

I don' really know the map on these. I know anything, I think over 3% copper, 3%, grade GHK typically isn't allowed to be sold for human consumption or use. So I would probably not go over like 5% or 6%, but again, that's just off the top of my head. And I dont know what level it becomes toxic in the body. And I think for people running GHK as a peptide that they're injecting, as long as you're using the recommended dose for 8 to 12 weeks at a time, you are not really going to ever run into any issues.

Next question, how do you organize your peptides vials and how you chart and track your usage? I don't have like a notebook or anything. What I do do is I have a notion planner that I track everything. So I'll track my physique. I tracked my hormones, what hormones I'm using. And I tried my peptides and everything, so that's how I try that. Then as far as the use it or the vials, I actually will rip the labels off and just have the bio and then I take my own labels.

and I write on it what it is and then I right on that how much water I mixed into it. So I know exactly what I'm doing and when I am dosing it, but that's what, I would say. Hey, maybe if enough people would be interested in the notion planner I have, just built it for myself. I could sell that and make it like 20 bucks or something. When it comes to a lot of the stuff I had for A lot of times I'm like, it wouldn't even be worth my time to do it because I know people would buy it, but it's like if a hundred people buy, and it has 20 bucks, you know, is that $2,000? If I spend a bunch of time like making that and then no one really

buys it. So I don't know. It'd be one of those things like I have to like tease out the demand. What to Do If TURS Gives You Low Blood Sugar? What Peptides Help Improve Blood sugar? Which ones to avoid? I would say to avoid MK-677, because I did get some questions about that, which I'm not going to answer, cause I just think it's worthless, that will make your blood sugar worse. So I'd say, to, avoid that. Typically in my experience, even though people think that taking GLP-1 like trisapatite is going give them too low of blood trigger,

it actually kind of has more of a modulating effect. In my, experience it doesn't cause people to crash or have low blood sugar and even if it does lower the bloodsugar, they don't have the effects that people tend to have from low-blood sugar. So obviously if you have low bludger, there's one way to fix that. You eat sugar, but in my experience, like the GOP ones do better to modulate it rather than like suppressing it too far. And also to be like, well, if I take metformin alongside GOPs, is that going to cause my blood to go too low? My experience no.

Again, it works more to module it. Next question. This is going to be a longer one. So I'll strap in. Um, they said, I listened to your video on why peptides don't work for some people and made a list. They said I started HGH, H G H eight weeks ago at 17% body fat and 145 pounds. Now 19%, body, fat, and 150 pounds and the in body says that I've actually lost a pound of muscle and I have gained four pounds of fat. I don' know if this is the same person.

But I said it, was taking 2.2 I use daily and increased for about two weeks to four point warrant and decreased back down to 2 point two when that didn't I'm also coming off someone goes dead. Maybe this is the same person. I've gotten stronger, but I can tell I am fatter. Live five days a week and do the Stairmaster 5-6 per day for 20-30 minutes. Eating 1600 when I started. Reversed diet to 1850. Meat, sweet potatoes, protein powder, gluten free bread made from oats from a local company, ghee, cream cheese, cheese. coconut aminos plus honey in my baked chicken recipe I eat the same things daily 200 carbs 150 protein 50 grams of fat I had insulin resistance PCOS prior

to taking some glutide and losing 40 pounds and I redo my blood work three weeks ago my insulin resistant is gone my thyroid is good I refrigerate my HGH I dose every night So it sounds like they covered all their bases and Maybe this is the same person.

So I've got to be doing something wrong by getting this much fat and absolutely no muscle, spending so much money on, and I'm so bummed I can't afford a coaching call right now, but love some guidance if I was to listen to your HGH episode. Taking all of that into consideration, I, again, if you're not supplementing with desiccated thyroid, even if your thyroid numbers are normal, I could see this being a problem here. So again a lot of times when we look at the thyroid and again I'm on estradiol testosterone, progesterone levels are good.

I don't know what that means and I know delivery mechanisms. Again, almost all the time, especially when someone loses like in this case 40 pounds really fast, it can be traced back to that. Even if the Thyroid numbers were good, you could likely still benefit benefit from desiccated thyroid. A lot of people for whatever reason are really afraid of that, even though it's a natural supplement and just happens to be prescribed. Um, but that would be like almost all the time. I see this. That's what happens also too, to go to the HGH.

This sounds like it may be underground HTH, which in that case, it would not have the same effect as pharmaceutical HCH. Cause I've tried both and I know, but that's typically what happens. So I would also recommend shifting down the lifting days from five to three, and then focus on more longer, lower intensity, steady state cardio, because I think that is probably also stressing the nervous system out. Based on the parameters I've been given, those would be my best recommendations.

Um, next question. My 15 year old son is trying to gain weight and wants to start MK six, six six seven seven, uh, to help him increase his calories. What do you think from a safety perspective? I don't think safety prospector really worry about it, except that it will ruin your blood sugar. And I wouldn't just not use it at all. I know a lot of people will give their teenagers this and it helps them like eat enough so they can put on more weight. Yeah, maybe it works good, but in the longterm, I just think MK is not a great one to use. There's so much better things out there. Um.

I know for teenagers, this is an oral, so they don't have to inject it. But I would be more inclined to even use a growth hormone peptide for a teenager or growth from oneself. And I cannot recommend for children anything, So don' ask me about protocols for Children. That's not for YouTube. Next question, I have a question about stacking Reda and Terz. I am currently at 15mg of Terazapetide since March. Neither my doctor nor myself knew not to jump to higher doses so quick. Been on Terizapotide for 59 weeks total.

Am at a stall since July and just last week started 2mgs of Redda but still took my TerZapitide 15 at 10 days post last injection. How would you recommend I stack these now? I was planning on doing Terzz 15 milligrams every 10 days and read it every week. I'm scared to game way back, especially if I stopped his turds completely. And you talk about stacking, but it's always the low doses. So I don't see too much about what to do once you reach those high doses, I get my turs in a pen, so I can't split that, But I have peptides of peptide. Well, here is what I would do.

For this person, and I'll know if i've talked about this publicly as much, i would take those doses and actually start to wind them down. Now this person is stalling at the higher doses, but what the winding down is going to do is gonna allow some sort of like receptor reset in a way. So I would actually like take the doses down like 10 to 20% per week to the eventually to point of getting off them completely. And yes, you may be stall out, what you're gonna do in the process is allow yourself to get back on them faster. I will also use low dose naltrexone at starting at 0.5 milligrams probably gonna be close to like three milligrams after the first week or two to titrate up.

So I would take low dose naltrexol, I'd wind down the dose eventually until I'm like at nothing almost. And in that process, i'm going to build up a cellular reset and then maybe only have like two, three or four weeks off of the peptide completely. Then I'll reintroduce it at a lower dose. And I think if you combine the naltrexone with the wind down over like a four week period, so like take four weeks, winddown to zero, use naltrexol in the process, go another two to three weeks off, keep using naltraxon. Obviously you want to make sure your diet and lifestyle. If someone's taking this much of the peptide, to me, I see that their diet lifestyle is probably not in check.

So in process of you winding down, if your doing everything right and your hormonally optimized, You should be okay. And you shouldn't gain that much weight back if any, and then you're going to build up a tolerance. Then you can kind of reset and go back to like, Oh, I don't need to go to the higher doses. So that would be my recommendation is I'm more of a fan of like winding down. Even though you are not going really see an effect because you'll be winding on the dose, if you introduce the naltrexone, it's going help with that. You can come off completely, go two to three, four weeks off. Kind of in a six to eight week phase of coming down, and coming off and then you reintroduce it and hopefully in the process of re-introducing it,

you get a better response. So that's actually another good long form video for me to explain because I've helped people with this and just haven't talked about it a lot publicly. But basically to say like how you can come off high doses, then reintervene them at a more appropriate dose and do everything right. Um, would you do an HGH in-depth video? I actually have, so you can look up Hunter Williams HTH. I think it's like my HHH fat loss protocol. Um. And then they said as a separate question, can you use HCH immediately after an eight week test at IPA cycle during the eight-week receptor break?

Yes. Actually answer that, uh, unknowingly earlier, but yes, if you're taking tests on IPPA, take eight weeks off of that, use HGH and go back to testing it. But you could do that. How much would that be? That'd be two months on. So basically you'd have four months of it and do it three times per year. Then you're using HTH, what would be six months out of the year and then peptide six month out the other year? And then there you go. You're good. Can you do an episode on TRT benefits for women, also maybe specific peptides that women would benefit from? Sure. I would say too, if you are interested in women's stuff, go and check out my fiance, Taylor Reed coaching on YouTube.

She has the best women peptide videos, point blank, period. Who else is out there? She is the Best Peptide Videos for Women. So go look her up. If you don't know that, we probably should do a better job of doing more cross collaboration on our channels. Um, but anyway, go look that up, and I will be doing a testosterone episode soon for women. Um. What is PA 496H, a novel peptide that targets AMPK?

I don't know. They sent, this person sent me a study from Johns Hopkins. I'll look more into this. The, the only issue with this is like, there's a lot of these amazing studies out there. So what I would say is. I don't know. I will look up and do more research on it. And then also to, uh, it's kind of like blue balling people is if I go and tell all these people, like all of these things about these crazy things that are coming out, they're going to be so good for fat loss and longevity, and then you can't get them.

So until we can get it, I won't note it because I want to test it on myself and report back to you guys. I'm kind of as in the dark as a lot of people, but it helps to send it because we can get the word out. So this one was just more a recommendation of someone to use the Katsu device, which I think is either a blood flow restriction training or like a vibration. I've seen it before. Just don't remember exactly what it is. But they say using Katsu while on a GLP-1 helps maintain muscle.

That's actually a really good idea, whether it's like the blood for restriction or whatever sort of like, novel tech people have to help, you know, people maintain and gain muscle for people that for whatever reason struggle to go to the gym. It would be awesome to use alongside of the GOP1. So for all you people out there, check out the Katsu. I don't have an affiliate link. have them reach out and sponsor me. So another one on testosterone for women. Wow. You know why I filmed a testosterone-for-women video? So that one is coming up.

Pre, peri, and postmenopausal. Yes, I understand testosterone is important for woman. I get so many emails from women, almost like furious at me because they claim I don't talk about stuff for I do. And again, if you want the inside scoop on women's stuff, go check out my fiance Taylor's channel on YouTube. She speaks specifically to stuff for women. The stuff I talk about applies to women, it's the same for men. But as much as I can talk for stuff women I will never have a menstrual cycle, I'll never bear children, and I never know what it is like to be in the

body of a woman. I don't plan on doing so, so please go and check her out. You guys trust me and stuff. I'll do as much as I can. What to take when cycling off GLP-1 and growth hormone peptides so that you don't gain weight or you lost or lose muscle you gained. Desiccated thyroid, testosterone, human growth hormones itself, those are what I would do. And a lot of people make the mistake of using GLPs ones and they have hormones that are in the tank.

Which peptide works as nasal sprays? Typically ones that across the blood-burn barrier to have an effect on cognitive function. So pretty much like CMAX, CELANC, PT-141 can work with a nasal spray, OXYTOSIN works well as a nasals spray. I probably wouldn't use anything other ones, although they exist. I would like to see a video for those of us who are lean and fit for peptides can be used to maintain current weight body comp.

All a lot of the products are for weight loss without ongoing maintenance. It's pretty much the same thing. it's just relative to the dosing. So I'd say look up the Godstack on jcampbell.com and you can look at a couple of my other videos because what I talk about is obviously I'm a Fancy myself as a leaner and fit individual. How about Mazdutide? Well, Mazduetide is a GOP-1 and a glucagon agonist. So it's like retitrutide without the GIP. I haven't tried it, but I don't know why I would use Mazdotide instead of retritrutite because retrutitite has three stages of action where Mazdatide just

has two. Um, so I'm sure it is good and better than semaglutite, But I wouldn't use it over retretrutate. Next question, I was using CJC with Nodac for eight weeks. I love how I felt and look, and I'm currently cycled off. What is the meantime that I can cycle in to keep up the momentum or even just to maintain? 47-year-old female, workout five to six days a week. For a 47 year old female I would say jump straight to human growth hormone and then we can do that protocol we talked about where you cycle on and cycle off between your peptides and your growth hormones. And then eventually you'll probably just end up using growth on the cell.

Next question. This is a really good one regarding oxytocin. The cheat sheet says use as needed and several times I've taken 50 micrograms and had no effects My husband is disappointed lol. I am 52 and postmenopausal Should I try increasing the dose or maybe take it every day for a while? Or maybe it's just not effective for me I would say to that probably go up to like 150 to 200 micro grams. Everyone's a little bit different I recommend people start at 50 grams because it can cause a lot of flushing and and bowel movement. But I think for someone, if they don't have any response to it, I use 200 micrograms all the time and you can do that.

I would say if you're using the nasal spray, you'd actually want to go higher because typically there's a little bit less efficacy for dose for those. So, but I'd say go to 150 micro grams, see how that does. And you'll probably notice it for one and two. Also say introduce PT 141 and then obviously to make sure you have testosterone. because that's going to be huge for a woman's sex drive, especially for someone with post-menopausal. But also too, I would look at adding in estrogen because it's gonna help with a lot of libido issues that a post menopause woman may be experiencing.

Next question, should I feel the effects of CMAX pretty quickly or is that something that is just more subtle or may take a while? It kind of depends. I prefer the Inacetal C-Max Amidate, but also too, this is relative to the dosing. So like a lot of dosage you're going to see like 100 to 300 micrograms, But I would say like go up to one milligram. And I think that's usually where people will see a better response, at least one that they notice. This question I'll say it, but I don't really have an answer. So someone said, I would like for your guidance on how to handle raw peptide powder.

I wouldn't. shelf stable for as long. It also mentioned that you buy mostly raw powder these days. I don't, but it's much cheaper, isn't it? It is. So my question is, what tools do you use to extract away five milligrams of raw power powder, very small amount, and put it into bio for reconstitution? How are we going to be done without advanced lab equipment? I would personally not do that. Again, I understand people trying to save money.

All of us are, but I just wouldn't do that unless you're like an advanced chemist and know what you are doing. So I will never teach people how to do just because I don't want to myself. And I have places that I buy from that. I trust. That is it for the questions. We actually went pretty long today. It ended up being 45 minutes. Let me know what you think of this one, guys. And again, remember these are made excellent because you ask excellent questions. So I would say if you have any questions you want answered within the next month, hop down to the link in the description to go to that question box and

leave me your question. I'll make sure I do my best to get to it. Typically, if do ask me a how to reconstitute question, I'm not going to answer that. uh, cause it's out there, but anything else is pretty much fair game. So appreciate you guys much love. Uh, don't forget to check out the peptide cheat sheet, sign up for the email newsletter. That's where it really at. And obviously to fully optimize health. If you want to be in the best community of, uh peptides users, therapeutic common users and biohackers on the planet. Much love again. Thank you so much. I have the audience on planet, I hope you enjoy your holidays with your family and share some love with you.

Your family this holiday. Cause that's the most important thing. All this stuff is just to make us healthier so that we can love more and share that love with other people. So thank you guys much love and I'll talk to you in the next one. Peace.