Peptide Q&A · December 2025

0:09 Hey everybody, this is Hunter Williams. I hope you're doing amazing wherever you might be. Well, This is long overdue. It is December now, and I am finally catching up to some of your questions, finally. But if you look down in the description up wherever you're watching this video, whether it's Spotify or iTunes, I actually have a link that you can submit

0:41 a video topic request, or if just want me to answer a question. It's a shorter question in one of these Q&A videos. To me, this is one the most helpful tools I have to interact with my audience. because I get so many comments, so any Instagram message, some of those things. This helps me organize and categorize all the questions to really understand what people want to learn more about or what I can do a better job of educating them about. So again, that is one of the most valuable tools that I have. Make sure that if you do have questions you want me to answer that you check that out.

1:11 Obviously, if your inside of my private group, which is called Axion Collective, The link will be down in description for that. You can obviously join that and we have live Q&A calls to where you can come on live and ask me questions every Thursday night at 8 p.m. Eastern. But in the meantime, if you don't wanna join the group, that is what these videos are for. I can't promise that I get to every question, but I will do my best. You can make sure you're on the email list. The link will also always be on my email to submit a topic or suggestion. And then also too, you can fill that form out.

1:41 It goes directly to me. I have a handy-dandy little document right here that I'm going to go through to answer the questions. Without further ado, let's get into it. and I've not curated all of these, so forgive me if I take a little bit of a pause between questions because some of them are either super long that people send me, which is totally fine, or they're not really questions. They really just want to send me something. So I will have to scroll through and go through those. Also too, if you want make sure that I see something, send it through that.

2:12 A lot of times people send you new studies or new things that they found out about certain peptides. That's the guaranteed way to make that see it because that is one thing I look at every single day of what people sent me. Sometimes my email inbox is just overflowing and I don't have time to get to all of my emails. All right. Oral dosing versus subcutaneous for five amino, I like one milligram per day for 5-amino injected sub-cutaneously. You can also do it intramuscularly if you want to. I feel the onset of the effects are much more rapid if it do intromuscally.

2:44 However, it's still really good to do subq versus oral. The dosage that I think you really see benefit is like 100 to 150 milligrams. Oral bioavailability is four or five amino. I'm sure it's obviously different for everyone, but I do know the injected works much better at those doses. Now I have heard of people going as high as five or 10 milligrams per day injected five of amino, if you want to do that more power to you, to me, one milligram is great.

3:14 Two milligrams for me is really strong. And so I've never gone over two, two and a half milligrams because it was just so strong, The energy was so much, I felt a little too sped up and a bit too racy. But you might not be me, and so you may need more of a dose to feel that same effect. Again, there's no right or wrong answer, but for me a great starting dose is 500 mcg or 1 mg. two milligrams as high as I would ever want to go. But hey, if five milligrams or 10 milligrams a day works for you, I have nothing against that. I just don't find it to be enjoyable.

3:45 Whereas one milligrams is really enjoyable, and I love it. That's one of those peptides. It's not a peptide, it's a small molecule, but I think it is one those ones. The injected five amino I've heard only the best things about it from people. Not really heard anyone say it didn't do anything for me if they got to the right dose. And I'll leave it at that, Moving along, flying with peptides. Yeah, Flying with Peptides, what I do is I put everything in an insulin cooler and then I will put that in my checked bag. And so I know it's a pain in the butt to have a checked back because then you got to go wait at the end of the flight to pick it up.

4:17 You got a check-in earlier and all that stuff. That's the easiest thing for me. I avoid any of scrutiny that I would have with the TSA when I'd put it in check bag I have heard of people putting it in their carry on bag and a lot of don't have problems. They just say it's their medication if they get asked, but just not something I want to do. So I get an insulin cooler, put the ice packs in there. I'll put my little peptide pins in. There are usually three or three to five different pins, depending on whatever I'm using the time. And I will take that with me. That usually ends up being the easiest thing, especially because I am usually to the next destination at a hotel where I can get a refrigerator and put

4:51 in within 24 hours. The peptides are fine. Next question. Essential amino acids, are they beneficial when not on and or on a GLP-1 and then what about injection form? I think essential amino acid are amazing, I take them every day. I get mine from unmatched supplements, they have the best tasting ones, the ones in my opinion. And they have them in a couple of different products. They have a longevity, uh, EAA formulation, and they also have an intro workout with essential amino acids in it, which is perfect for me.

5:25 Cause that's what I do anyway. And so they shout out to Chris Gethin came up with a great product for that. However, you can inject them. So there's websites like soma chems or better through biology that have different blends that has essential, amino acid in them, obviously the. efficaciousness of that is much better, and I love taking those pre-workout. I like essential amino acids. Whether or not you're on a GLP-1 that can be beneficial, I think especially on GLPs, they're going to be that much more beneficial. This will be a longer video, but I did want to talk about it.

5:57 Someone asked, can you address MS, aka multiple sclerosis and a peptide protocol for it? There's a lot out there that's more of a neurological issue. And so cerebral Iosin would be great. The peptides P21 would great, Huminin would That's where I would start. I also think SS 31 could be really beneficial to someone with that. So that's why I start, I'd also look at hormone replacement therapy because a lot of times people with MS have very suppressed hormone, whether they're a man or a woman.

6:28 Here's a good one, and I've wanted to talk more about this, is B7-33. B 7- 33 is a newer peptide that is making the rounds in the research world. I don't know that we have any human trials on it yet, but it's basically an anti-fibrotic and also a peptides that lowers blood pressure. There's lot of really cool things it does. If you look at the search, this person says, what is the dosing protocol? I know from my own experience, I have heard of people doing one milligram per day. basically it usually comes in like a five or a six milligram vial and you would do one milligram per day.

7:02 This person said some people are doing 300 micrograms every six hours. I think you could do that, but start there. If you, if you always want to start lower, you can start with 300 micrograms and then work your way up to one milligrams. So somewhere in that 300-microgram to 1-milligram per-day range, I would think would be good. Next question, and I this one would a good answer. Can you possibly, Can you possibly occasionally dose testosterone before a date? I heard it on a podcast, but the patient's doc never addressed the question.

7:33 I think you definitely can. It depends on the ester, meaning that if you dose Testosterone Cypionate before date to get a pick-me-up effect, I don't know that you'll necessarily feel that per se. You may feel it. Some people may. However, it depends testosterone suspension, which is testosterone and water, you get an immediate effect. If you use testosterone propionate, You get a little bit more of an intermediate effect than you would thecipianate. And then you could use something like testosterone cream, Which obviously has an immediately effect too. I think there's a use case for people to have a bit of testosterone on hand, like before a date night or like a workout or something where you might need

8:10 a bump. I think you can definitely do that. But if you inject testosterone, stipulate or testosterone and anti before a date, eh, I don't really know if we're going to feel anything, but I like the thought and you just want to be more strategic about which one you're using. Someone asked, just started on my peptide journey, seeing a ton of information about TFA and some peptides, how relevant is to get peptids without T FA? Obviously you want to minimize your exposure to T F A. I forget what it stands for, but basically it would be something that is a residue in the peptid that could cause harm to the end user if the amount was

8:46 too high. What I would do is just look at the COA of the peptides you were buying and make sure, if you can, to see if they have endotoxin and heavy metal testing. And if your good there, you're probably going to be good on TFA's. Also, some COAs will have a TfA amount on there and to se if it conforms, meaning that it's within the bounds of what would be acceptable and safe from a But definitely want to avoid at all costs and just ask whatever supplier you're getting them from if they test for that or if have the ability to prove

9:16 it would be good to show. There's a peptide called P21 touching on the brain benefits, of course, and note on that I help benefits. I'd love, love love P 21. haven't made a full video about it yet. Although I am working on it dosing wise, I think you could start on a low end at 100 micrograms. 250 micro grams for me to be the sweet spot, but I love p 21 it is not like a stimulant, nootropic peptides, But it definitely improves brain health. And I loved how I feel on I just get a really good, clean mental energy.

9:48 And it seems like the effects are cumulative as well. I love P21. It's going to be one that I am talking more about in the future. Let's see. This one is about SGLT2 inhibitors in metformin. Is there dual anti-hyperglycemic therapy and the risk of metabolic acidosis in tight tube diabetes? I don't know per se. There's probably some papers on that. I will say I love 500 milligrams per day of met formin with 25 milligrams of Jordiance.

10:23 is one of the most powerful things you can do for anti-aging and longevity. Maybe the SGLT2s at some point remove the need for metformin. I haven't gone all the way there yet, but I think I'm pretty close. So just love met formin for the gut health benefits that it seems to help protect my gut and keep me from having any sort of weird reactions to dairy or gluten or things like that. Not that I eat those, on a super regular basis, but it is nice to have. I feel like Metformin still beyond the SGLT2 has kind of like a bulletproof effect on my gut, meaning that it protects my good.

11:02 Moving along. I'm getting sore nodule-like areas in my thighs and belly that are remaining very tender after doing peptides for many months. This is happening even with rotating where I place the needle each time. Any suggestions to help soften or reduce this? Obviously you want to move the injection site around as much as you possibly can. It will happen that you end up getting that. Now, what would we do if we're rotating as much as we can? I really love doing a lacrosse pole, and you can even do that on your belly. So if you lay on you belly and then sit a little lacosse ball around it, kind of use that as a foam roller.

11:34 Sometimes it's harder to use a form roller in those areas of your body, but if get a lot of lacroce ball or a spiky ball that is not super hard, that's a bit more squishy, you could put that there. And so I like doing that because that helps rub out the fascia there, obviously just sometimes it is a more tender on the belly than it would be on like your glutes or your calves. Uh, doing so some of these are a little bit older too, cause I've been a bad boy. And so, some these I have already answered in videos.

12:05 For instance, I made a video on testogen. I've been searching the VIP by regular peptide, which is vasoactive intestinal peptides discovered. It helps my erectile dysfunction due to type two diabetes, 20 units at the most, if possible, can do a video on to this topic. Yeah. I think VIP is one of the best peptids that no one talks about. Obviously there's a lung health benefit.

12:36 But it does work as a vasodilator, which means that it increases blood flow. And in this case, this man was saying that he got a definite benefit to erectile dysfunction, Which I think is pretty cool as well because I haven't heard that. So not really a question, but a very, very prescient point that I Think is good for people to know about and they could possibly experiment with. A lot of people talk about PT-141 that does tend to have a little bit of vaso dilatory effect for erections in men. and arousal in women. However, I think something like VIP is going to be that much better.

13:07 I just be careful about blending those two together, because it might be a little strong, it may get a bit nauseous. Just moving along, making sure I'm getting to a good question here. This would be a one second talk a little bit about this. What would a be good stack when you cycle off GLP-1s? My main focus is appetite control. I also know it's a time to add mass back. So another stack for possible muscle gain and fat burning when my appetite goes crazy coming off trans-appetite.

13:41 I really like again for appetites control or for Glypron, which is the new oral GLP one small molecule for me works amazing for appetite control. I usually at like 12 to 18 milligrams get incredible appetite and obviously it's different than trisapatite or retitrutide. And so you could use that in your off cycle. It burns as much fat as retritrutite does. However, the appetite suppression is as good if not better in a lot of cases. Now you could also use something like coagulantide, which works on a completely different pathway, but a lot of people just don't do well on coaguilentide.

14:15 So I would, you know, say coagueilantides or Orphoraglipron would be my recommendation in an off cycle. And you should get all the appetite suppression you want, obviously in a dose dependent manner from those. Just moving along. A lot of these questions I get are about sourcing, which are fine, but again, that is something that I have to relegate to the email list. That's not something I can really talk about on public platforms.

14:48 A lotta people wanna know about peptide pins. I've made videos, if you're on my email lists, you can go to Dropbox, and there's a video where I show how to make and use a peptides pin. Yeah, this person, I made a videos about split dosing GLPs. They said it could go further three days a week, four days, a weak, how to do that considering you would have to skip a day or have two days in a row. Every other day seems workable as there are no weird days. Yeah. So if you wanted to, do every other. Obviously it would be like Monday, Wednesday, Friday, Sunday, Tuesday, Thursday, Saturday, Monday.

15:21 And so you could do. That. I think every. Other day just makes it easy for you. Whatever, whatever works best for. How to. Do it in. A seven day week. There we go. Brain Protocol Pack for Dementia, kind of like I mentioned before, I think Cerebral Iosin, P21, Huminen are all good places to start. I actually think a microdose of a GLP like Retatrutide is also a great place to Yeah, taurine supplementation with the Wolverine stack.

15:56 I think tauring is just good to take with any peptide. Tauring it's such an amazing molecule. And again, it mitigates some of the weird side effects people get with peptides. For instance, when people take it at a trutide, they can raise their heart rate. A lot of times tauren will help normalize that and bring it down. The dose is kind of dependent on what you need. Usually I take up to five grams of tauran per day. You may only need one to two grams, but I find five gram is a sweet spot for me based on Here's one that's probably relevant.

16:28 Someone said they purchased BPC and TB 500 as a nasal spray, but want to use it as an injection. Could I just add backwater to the powder and use as injectable? I probably wouldn't do that. I don't know where they purchase this from or whatever, But if you buy something as nasal-spray, I'd probably would not inject it. Just moving along. Someone says, I've started taking HGH at 1IU, AMMP and given that what other muscle building and or fat loss peptides are complimentary and what peptide

17:05 would be redundant or unuseful. I like a GLP-1, obviously a fatloss is the goal with HTH. You could also always try something like an IGF-1 LR-3. You can also use something, like a BPC and TB-500 to help up-regulate the growth hormone receptor sensitivity. That works really well in tandem with that. And then something L-carnitine. I think that would be a great start. So HEH, maybe a little bit of IG-F post-workout, and then B-PC TB 500 and L carnitin, you'll be well on your way. you will notice an outsize effect from adding those things to the HEh.

17:36 Again, it's pretty simple. It's not anything super sexy, but there is a benefit there. I've been getting asked a lot of questions about injectable SLU PP332. To be honest, I don't know what I would dose it at because I haven't used it yet. And I know as the person or one of the people that talks about peptides, that may sound like I'm Not meeting my expectations. I have just been very weary of injecting SLU PP332 because I don't have a good source for it yet.

18:08 And I want to make sure if I'm getting it, that it's a source that actually is what it says it is and that I would using it right. So I've heard good things. Actually heard from a lot of people that the injection doesn't do much more than the oral version. get great effects out of the oral version. So I don't know. I'm not going to tell people to go inject it. One, because I've not done it myself and I haven't seen any data or basically information that would lead me to believe that it would be any better than the world.

18:42 Someone says, I'm looking for advice on supporting my HPA axis and testosterone. Tried testogen, felt strong benefits for two weeks, then it wore off. Also tried glandicort with minimal benefit. That's the adrenal gland bioregulator. This person says their FSH and LH is normal. Free T is low, total T about 400, which is also low. And their TSH is around four. Suspect my low cortisol, HBA dysfunction is contributing to low testosterone, any thoughts on addressing the underlying HBD dysfunction? Lifestyle is pretty down. Yeah, think this is one of those things, all lifestyle variables are controlled for that testosterone will have to come into the picture eventually.

19:17 I think you're probably going to get, you could look at HCG, look it in clomophene. Those would be short-term solutions in my opinion. But unfortunately where we live in the uncomfortable and inconvenient truth is that many men need testosterone therapy when they don't want to go on it. And of course I'm on testosterone therapy. I am very open about talking about that. It started when I was 27 years old and it completely changed my life. As it stands right now, we don't have a peptide that I would say replaces it.

19:49 There is this peptide out there that's being studied. It's called ACE-167 that is supposed to help with cholesterol synthesis in the testes. Now, whether that works or not, I don't know, but I have seen that making the rounds in research world. So, hey, maybe that a peptides that doesn't necessarily work on the HPA, it actually works directly in a testese. There's obviously things like kisspeptin, gonadarelin that do a little bit too. But again, don' think they're gonna replace testosterone. And then also in case like this, If the HPA axis is not working well, you probably need growth hormone or growth-hormone peptide,

20:23 and you'll probably desiccated thyroid as well. If you're already on TRT, how do you combine it with testigen? I'm doing this right now as part of my testing for fertility protocol. So I add in two milligrams of testogen a day, five days on, two days off. And what I want to do is use that for 30 days, six weeks and see where my fertility is. It might not change at all, or it might be beneficial. I do notice that I seem to have a little bit more of like an HCG feeling without some of the weird side effects of HCGs.

20:57 So I like, I don't know that it raises my testosterone anymore than the testosterone therapy does, but so far I've been loving Testogen and I do notice probably it does feel like it's bumped up my thyroid function a little bit, which is something that is proven to do. And so I think for guys that are not on thyroid and not TRT, it could be good, But if you're already on it, that would be my protocol. Erectile dysfunction in men on TRT is too high T possible and some symptoms, side effects. I think it probably is.

21:27 It's probably a lot higher number than your doctor would tell you. They'll tell 900 testosterone is way too hot when it could even be low in some cases. There is a point. Whether the level is 2000, whether it's 5000, or whether is 20,000, I it yet to see. What we probably could all agree on is that there will be a level of testosterone where the side effects, meaning that the increase in blood pressure, the increased in nervous system activation, which is gonna be a different dose for everyone, The side-effects become a burden so much so that it could

22:01 affect erectile function. And I think there's probably a sweet spot to where we would say, okay, Maybe 2000 is a sweet spot for me. But if I go to 5,000, the bloating and the increase in blood pressure and things that not for everyone, but for some people may happen at that level would potentially affect erectile dysfunction. I think if anything, it could be the higher blood in a lot of cases that would mess with the erectal function. Peptide stack for seasonal allergies. Yeah, I thing my first go-to would be thymus and alpha 1. Thymalin would also be another really good one to add.

22:36 I also really like KPV. And then you could also potentially add an LL37 if you feel like there's any sort of like bacterial or viral or mold type stuff going on there because it's an anti-microbial agent. This is a good question I've talked about before, but they say does metformin affect your blood sugar if want to take it for its health benefits, But already have low to normal blood I think yes and no, metformin does not directly lower your blood sugar like insulin would.

23:10 However, I have seen it in people that are very insulin sensitive potentially drop it a little too low. The danger is not super, the risk is high, I will say. There's not like a high risk in doing that. You're not gonna notice a big benefit. you're just gonna be a little bit more insulin sensitive with metformin. So the point is yes and no, but it's gonna not be dramatic and I wouldn't worry about it if I wanted to take met formin for the anti-aging benefits.

23:40 Should a female inject Ipermrelin before a workout in the morning? Would that be a benefit or a waste? And does a calorie free pre-workout containing caffeine negate the effects of the peptide? Yeah, I think you can. Obviously with growth hormone peptides, if you have higher insulin, they're going to work less effective. It's not that they are not going work at all. I Think if wanted to, you could definitely take it pre workout, but I would, my opinion would be to still eat food because if take on an empty stomach and only food, especially if it's a strength training workout.

24:10 I think it is fine to take if you're doing it before cardio, like a fast cardio session. But if its a strong training work out, I want food in my system. And so maybe you could do it, before, maybe could you do after. the efficacy of a single injection, I would take it away from food and not do it pre-workout. But you could break up your dose and take a pre workout with food, knowing that's not going to work as well, but it's still going work a little bit. And then take the other dose at night, that that one's going be better because you're doing it on an empty stomach.

24:40 Up to you at the end of the day. Obviously it is a personal preference thing. So I'll leave that up to Here's a good one. Cloudy peptides. I'd say one out of 10 of my peptide go cloudy post-reconstitution, usually one or two weeks later. If you look closely, you can see it's actually mostly small threads floating around. First of all, assuming this is not okay to inject in best of disregard. It kind of depends on the peptid. Most of the time though, if a peptite is cloudy inside the vial, it is no longer good.

25:10 That means it has been denatured. This person says, I get peptized from reputable companies, use backwater to swap the vials. Transfer to insulin pen cartridges. Yeah, it could be. So a lot of times when you mix peptides together, if they do not play well together they'll get cloudy, meaning that they denatured. And so usually that's my rule of thumb with like, Hey, okay. A peptide is denatured. Now in this case, they're talking about the threads, which sometimes you'll see like an NAD or glutathione, it can kind of like crystallize. So I don't know what you could do if there's like crystalization of a peptides is put a little bit of acetic acid solution,

25:43 like maybe 10 to 20 units at the most in there. And that usually will help break up those crystals and get it more to like a pH that it's manageable. But I mean, It is what it is. If it's one out of 10 peptides is obviously not really a sourcing issue. It sounds like because the other ones are doing fine. I think it was just more of the peptide getting denatured at which point it is useless. So it isn't really worth injecting. Let's see, drinking alcohol while taking testosterone or Rachele run, how bad does it affect the peptide?

26:17 I wouldn't say it doesn't badly affect a peptid, it badly affects your body. So it's kind of like saying, okay, I ate a salad for lunch, but I'm going to eat cherry pie for dinner. Okay, you had a healthy lunch but you got a bad dinner, so does that make the salad bad for you? No, But it kind negates the health progress per se. Obviously, everyone's not going to be like this. I choose not to drink alcohol. It's a part of my life. My life is much better without alcohol in it.

27:00 and your peptides are gonna work a lot better without it. Now I realize not everyone is going to be a tea totaler and choose not to consume alcohol, but in that case, I will say, just be conscious that don't expect tessameralin to dramatically change your life if you're still consuming alcohol. Even if it's just one to two times per week, it will limit the benefits, not because it is gonna interact with the tessemeralins per se, But it can interact through their body and it a toxin. So again, if your toxifying the body, It is not gonna have good benefits.

27:30 I know it probably sounds like I don't have sympathy there, but I would say if you're going to drink alcohol, just have some NAD, have them glutathione, and have 5-amino on hand because it rapidly depletes NID levels, which is obviously not going be good long term. Could you run in the five days before vacation the suggested dose of 500 micrograms per day of Melanotan-1 followed by the 5 days at 1 milligram when you're actually on vacation enjoying the sun? Yes, absolutely. So do a little bit of a loading phase leading up into the vacation with Melantan 1 to build a base and then take up the dose if you are going to have a

28:05 lot of sun exposure at the beach. That's what I do. Then they say question two, I always go on a beach vacation during January to get away from the snow where I live. There are multiple days where I do not see the sun during this time. Can I take the peptide and use it in the tanning beds with the same results? I'm not a big fan of the Tanning Beds, but yes, you could do that. I have heard of people saying that Melanin-10-1 enhances the TAN that they get from the tannin bed. So maybe, maybe it actually is beneficial because you're not getting as much inflammation from tannings bed and maybe there's more advanced tanting beds now that don't have those same effects.

28:35 so I would say, yes you probably could. Do you believe it would be beneficial to use BPC 157 or the Wolverine blend for my bulge disc in my lower back? It's not bulging enough to pinch anything, but was curious if it will help with pain or movement if not help absorb heal. Yeah, you definitely could. I would add in Carlax. Carlex would have a more profound effect on the bulged disc, fool myself into thinking that it's going to solve the problem.

29:06 Again, peptides don't necessarily solve a lot of structural issues in themselves. They can help with recovery, they can helps with inflammation, that can't help the pain. But if there's something structurally wrong, a lotta times that has to be corrected. And so obviously every bulging disc case would be different. I think it's better to take peptides than not take them with it, but I just always forewarn people it is not going to be something that dramatically fixes everything right away.

29:38 Someone said, I read your newsletter about timing for GH peptides. I'm already very lean and need to increase muscle. And only to do strength training in the afternoons. Is evening dosing the way to go? I think that would be fine. Just moving along. What stack of peptides you recommend for energy, lose weight, and gain muscle as a 36 year old female?

30:08 I think that would be pretty easy. Lose weight would right atrurotide. Gain muscle would Ipermrelin, or Ipermelin and CJC for a female. And then energy you could throw in some MOTC and 5-amino. Boom, you're off to a races. Those, what would that be? Four to five peptide right there. would absolutely be life-changing. And obviously 36 year old female probably want to get your hormones checked, could be deficient in testosterone, probably deficien in progesterone if you're not sleeping well.

30:39 Yeah, I get this question a lot. Someone that's 64 years old, they're pretty healthy. They're using peptides. they started Tessemerolin and Ipomerolin. I know this is going to take longer to see results, but I'm wondering if I am too old to get good results? I wouldn't say you're too to old get results on it. You will get much better results in HDH, as do most people regardless of age. But I think, particularly in the realm of someone that is in their 60s, people in 60 respond better to exogenous HDh. Again, it doesn't mean that the peptide is not going work or that it's bad.

31:09 It's just that they're usually the better option is going to be HGH for someone that age. Coagulantide in combination with Reda, I think that's great to do. I like a four to one ratio of Redo to Coaguilentide, meaning that if for every one milligram of red, uh, like 250 micrograms of coagulin tides. So if I'm doing two milligrams of RETTA, 500 micro grams or 0.5 milligrams coaguillentides, and you can kind of scale it out from there based on what you need.

31:39 But a lot of people don't get the appetite suppression they want on Reta. which I think a lot of times comes from the increase in metabolism because they're burning more calories because of the glucagon agonism. So that would be my answer. Play around with it and see what you like best, obviously. But there are some research companies that do make those as a blend now. Just moving along. Benefits of creatine for women starting in 20s? Absolutely. If you're a woman in your 20's, you should take creatinine.

32:10 I definitely think you can do that. What's the difference between ATX 304 and BAM 15 plus SLU? ATx 30 4 is I would say more of a longevity. It is it is a quote unquote fat burner because it activates AMPK. So it indirectly can help with fat burning. I think ATX is more of a longevity type molecule that you could use all the time. And maybe ATx, because of what it does, could even be better to replace metformin than BAM or SLU. Bam is obviously a mitochondrial coupler.

32:42 SLu is a small molecule that is an estrogen receptor agonist that basically works on PGC one alpha and all these other things to help improve mitochondrial biogenesis. And so obviously all those have a use place and I've used them all. I would say ATX would be more one that I think you can use more of the time. Whereas BAM and SLU, I'd like to cycle off those more or less every eight to 12 weeks.

33:12 Chronic pain peptides and how we, each one mitigates pain. I like ARA290 for chronic pain, that would be the first line defense. Obviously then you could bring in Cardilax, you can bring it in BPC and TB 500. So I would say hierarchy would BRA 290, then Cardalax then BTC TB500. obviously all the dosing was on the cheat sheet, I don't need to rehash that here, but it's also good. Someone said they started taking SLU PP332 at a hundred micrograms and have the craziest fatigue that makes me sleep throughout the afternoon.

33:48 And they switched to the night dosing. Based on my understanding from other research that I have seen and anecdotes from people, I think what SL is probably doing is it's reflecting the mitochondrial state, meaning that if your mitochondria are impaired, it could potentially amplify the impairment rather than amplify them mitochondrion. What does that mean? I think probably you could benefit from using SS31 before SLU because it would help repair the structure of the mitochondria to which then you can use SLu to amplify that new repaired structure to get the benefit.

34:20 And I have heard of that and I thing what it is, is that people have mitochondrial impairment and it's amplifying through gene signaling the impairment of mitochondrion which could cause the fatigue. I've had terrible resting heart rate and HRV while on Reta the past three months. I'm going to switch to Terz, hoping to have a better sleep recovery while I still have the improved biomarkers out on Reda. So, I mean, maybe not so much around the liver because Red does more on the lever than Ter's appetite does, but yeah, absolutely. It's going move direction.

34:50 And I always tell people like Terza appetite is still an amazing compound. If Red is not working for you, do not get FOMO around going back to terz appetite. Terzer appetite's amazing. I like it is almost as good as red. I think there's just a little bit more fat loss benefit from right. But yeah, sometimes the red, the increase in heart rate is too much for people and they do better on her's appetite. So I love it. There's been a lot of talk about GHKTU peptide and darker skin.

35:20 What are your thoughts on it? Yeah. I think it depends on the person. It definitely can cause darker in some people. And to that, I would say probably not use it. Or if you want to lighten your skin a little bit, you can also use glutathione. So glutothione is something you could use for skin lightening. You know, obviously this dose dependent, the higher the dose, so the more it's going to like your scan. But I know that's a concern for some and it definitely, definitely could happen. I do want to drop this.

35:51 I don't know anything about this, but someone sent me there is a peptide called LZ1 for acne. And they stack it. They're stacking LL37 and KPV. I wish I would have had that when I was prescribed antibiotics for my acne as a teenager, because those made my life really bad. But no, I will look into that. And if you guys are listening to this, i will drop stuff like there in that because the more we know about it, the better.

36:21 So I don't know anything about, but it could be cool to explore. For the NAD plus MATC5 amino stack, N80 plus seems to need to be an IM injection. So we do this all IM since it's all together. You could do that IM, you could it SUBQ. It's up to you. I would say if you want it to hit faster, do IM. If you wanna a little bit more sustained release, and do SUBCU. Do SUPCU first just to make sure it is not too stimulating. And then if wanted to try moving IM you can do it as well.

36:53 Someone said I request that you start your own group. Well, I do have that now, so you can check out the link in the description for that. It's called the Axion Collective. Have I done a video on hypothyroidism? Yes, have. I could probably do many, many more though, especially in relation to testosterone replacement therapy. And we'll go through a couple more here because I know we're right at like 37 minutes right now. Do you have any experience with modafinil?

37:24 I don't, I know that probably makes me less of a biohacker. I've just never needed modaffinill from a focus standpoint. Always tell people though that I have coached or walked through that. Start with 50 milligrams, you might not feel anything. And then 200 milligrams per day would be the upper end of the range. But also too, what I would say is if you're going to use it, don' use on a daily basis. Use it as needed and then on the days that you're not taking a backfill with Alpha GPC just to help with some of the recovery because modafinil is so powerful in driving neurogenesis.

37:55 So start with 50 milligrams and kind of go up from there but I wouldn't go over 200 milligrams per day. How to get rid of floaters in the eyes. I've seen a lot of good things with BPC, TB500, KPV, eye drops and also SS31 eye drop so I have seen those do wonders. Should you use Prostomax or Libidon for an enlarged prostate? I think you should do both. Then you also should use another peptide called Desolute that you would do. I've got the dosing for that on the cheat sheet. That one works a little bit more on bladder but also helps the prostate.

38:35 This is a good idea here. Someone just says, have different people submit their personal daily regimen and critique it, show benefits, discuss the positive negatives, actually be a idea. I'd love to actually do that on some of our live streams, which we will be doing more of very soon. We're in the process of making a cool podcast studio. I was listening to a podcast, they said BPC-147 can increase the size of tumor, so that increases the sizes of lipomas. I don't know, I would say I wouldn't inject Bpc directly into a tumor because it can be a growth factor, which could cause it to grow.

39:10 So again, we don' have a lot of data on that. And in some cases, there's a study where BPc shrunk tumors, not shrink, shrink's not a word, but shrug tumors. It's just one of those things we really don''t know yet. Let's see. HGH versus HHFRAG 176191 47 year old optimized woman.

39:43 So I don't think HFrag does that much. If I was going to use another one that's similar, I would use AOD 9604 and I will do like 300 to 400 micrograms of Aod. That's going to be basically the fat burning fragment out of the growth hormone sequence versus growth hormones itself. So you don't get any of IGF benefits. You just get more of fat-burning benefits, so they're not the same thing. An HH frag is basically very similar to AOD 9604. I think Aod is probably a little bit better and I would use like 300 or 400 micrograms with that.

40:20 And I'll close out with this. This is a question around women and testosterone. Oh, excuse me, this is not a woman, but they say this a man. So man and testosterone. They say, I'm 61 years old, have been on 100 milligram once a week of testosterone for three weeks. I am having a side effect of feeling lightheaded at times. One, there's going to be an adjustment period of getting used to the testosterone and it might take a couple more months for you to acclimate to it. But also two, what I would do is break up that dosing into three times per week.

40:53 I think the dosage might be a little too low, but what i would is just take the 100 milligrams and then break it up into 3 shots of 33 milligrams, and maybe start to increase the dose over time. But typically you're not going to have the same peak and trough with the splitting up of the dose instead of doing one dose. And again, I know if you are someone that listens to me a lot, you were probably like, how do people still do this? But it's just what a lotta doctors prescribe to people. So I would move from doing once a week into three times a weeks. Keep the dosage the the if feel okay, and then see where you land from there.

41:25 Let's do one more. Let me find a good one here. Peptides used post-surgery. I'm a 58 year old woman having a knee replacement in December. What peptides should I use after? For that, I really like BPC 157 TB 500. You could use GHKCU and then I would also use KPV and Cardilax. So that would be five peptide right there that will absolutely benefit the post surgery to accelerate healing, to accelerated how you feel and everything.

41:58 check out the doses on the cheat sheet. And I'm gonna go ahead and shut it down. We're right at like 42 minutes for this one. So I'll go and turn it out for those one, but again, thank you guys so much. I always tell people without you, guys, I don't exist. and especially without the help I get from you guy submitting these questions, and I can't do videos like this. They really informed the content that I published. Am very spoiled because I have the best audience in the world. You guys give me all these question, you give all the feedback and then I could take that and use it to create some of the best content. So again, without you guys, I don't exist.

42:29 Don't forget, if you have a question, submit it down below. I'll do my best to get to it on these. Or if just want to make sure, If you want a message or something you wanted to give to me, you wanna make that I end up seeing it. That is the way to do so. Thank you guys so much. Whatever way it is that you support me, whether it's listening to this, liking, commenting, subscribing, I can't tell you how far that goes and helping me get to do what I do. So thank you, guys, so, much for that. I have the best audience in the world. And as we are in holiday season, and I just want to make sure people know how thankful I am for you. Guys, because this is a dream come true for me to get, to, do this.

43:00 and want, make, sure that, you know, whatever it, is, that ,you support, me that that go, a long way in helping, bring this content that hopefully improves your life. That's it for this one. Don't forget to submit your questions. and I will talk to you in the next one. Peace.