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Peptide Q&A · January 2025

2026-03-29 · 32:37 · 5 min read

Pulled together another batch of user-submitted questions and tried to knock out as many as I could. Covered everything from long COVID protocols to HGH timing to whether SARMs are worth messing with. Here are the highlights.

Long COVID and mold protocols

For long COVID symptoms like POTS, MCAS, fatigue, and dysautonomia, my first thought is immune system attacking itself. I'd start with thymosin alpha-1, KPV, VIP, LL-37, and a microdose of a GLP-1. Then add BPC-157 and TB-500 for inflammation. Get your hormones checked too, because there's usually some hormonal suppression happening.

For mold sickness and CIRS, very similar protocol. The difference is you're likely dealing with more mitochondrial dysfunction, so I'd add SS-31 and MOTS-c.

B12 dosing with metformin

I take 1 mL of B12 from Global Healing Center daily. I believe that's around 5,000 mcg, don't quote me. Make sure it's methylcobalamin, not cyanocobalamin. Same goes for injectable B12.

Sermorelin vs. tesamorelin for anti-aging

Tesamorelin all day. Sermorelin is kind of worthless. It's outdated and only gets promoted because certain influencers still talk about it.

Can you lose fat on retatrutide eating at maintenance?

Yes, I think you can recomp on retatrutide while eating at maintenance or even a slight surplus. You may not lose weight on the scale, but body fat percentage can drop. Retatrutide improves metabolism and nutrient partitioning. If you're lifting and managing insulin, you can absolutely recomp effectively.

Detoxing your brain from mindless scrolling

Retatrutide actually helps here because it dulls the dopamine spike. If you can't run that, look at 9-Me-BC, which is supposed to support dopamine signaling. I don't know enough about it to vouch personally, so do your own research.

My take on SARMs

I just don't go there. I've seen too many young guys take oral SARMs, shut down their natural testosterone, and have liver enzymes shoot through the roof. Whether that's the SARMs themselves or research companies cutting them with sawdust, I can't say.

There are too many other tools in the toolkit. Testosterone, some anabolics, and peptides do the trick for me. If you want to learn more, go check out Tony Huge. We did a podcast together. He's got a different opinion than I do and that's fine.

Knee osteoarthritis and BPC-157

It depends on how much cartilage is left. Bone on bone, probably not much you can do with peptides alone. What I've seen work is exosomes first to regrow cartilage, then BPC-157, TB-500, GHK, PEG-MGF, and growth hormone or GH peptides on top. Check out Dr. Jeffrey Gross at Recelebrate in Las Vegas. Exosomes seem more effective than stem cells and cheaper.

Are research peptides as good as Ozempic or Mounjaro?

In my opinion, yes, within about 5% efficacy. Sure, pharmaceutical grade is probably slightly better. Is it worth the price? No. If you know what you're doing, research peptides are plenty.

Retatrutide and heart issues

Take 2 to 3 grams of taurine per day. Everyone on a GLP-1 should be doing this. I've coached multiple people through tachycardia issues with retatrutide and taurine fixed it almost every time. A lot of the heart rate stuff is mineral and nutrient depletion plus neurotransmitter changes.

How long until HGH benefits kick in?

The big anatomical changes show up around six months, similar to testosterone. The first 5 to 6 weeks you might feel tired and bloated because your body is going through cellular remodeling. Give it time. If it's pharmaceutical grade GH, side effects can be more pronounced because the response is stronger.

I'd recommend HGH in the morning and your GH peptide at night. That's what I'm doing right now. Works really well for fat loss and sleep.

Low-dose HGH stacked with testosterone

Yes, this absolutely has a use case. I'm running 1 IU in the morning before fasted cardio and 2 mg of tesamorelin at night. Feels great. I wouldn't stay on for more than 8 to 12 weeks, then I'll cycle back to just HGH at 1 IU morning and 1 IU night.

For someone 50 plus, your liver doesn't convert HGH to IGF-1 as efficiently and your pituitary doesn't respond as strongly. So you'll get less of a response with peptides as you age, but they still do something for you.

HGH making you too hungry

This is HGH ramping up your metabolism. Your body is asking for fuel. Listen to it. If you're trying to add muscle, you can now eat more carbs and synthesize tissue. If you're worried about regaining fat, add a small dose of a GLP-1 peptide to manage appetite. But hunger from a higher metabolism is your body sending a real signal.

Oral testosterone

Not a fan. I don't think it's strong enough to give you the full therapeutic effects, and I think it's taxing on the liver. Stick with injectable.

Estrogen, body fat, and IGF-1

The leaner you get, the less aromatase enzyme you have, and the lower your estrogen drops. I've been there. Low estrogen kills your sex drive, wrecks your mood, and makes you feel terrible.

There's also some thinking that low estrogen impairs the conversion of growth hormone into IGF-1. So if you're suppressing estrogen, your growth hormone may not be doing what it should. I need to dig into the research more, but it's a real phenomenon.

This is why I don't recommend aromatase inhibitors. Estrogen has cardiovascular and neuroprotective benefits in men. Inhibiting estrogen is as bad as inhibiting DHT.

SARMs that aren't actually SARMs

MK-677 gets lumped in with SARMs because the same companies sell it, but it's a ghrelin agonist that increases growth hormone. Just understand what you're actually buying.

Stacking GLP-1s

If retatrutide alone doesn't suppress your appetite enough, add a little cagrilintide, or run half cagrilintide and half retatrutide.

Prostate enlargement

Bioregulators are the move. Libidon is the main one. Prostomax is supposed to work well too, but I haven't used it.

Burning the candle at both ends with HGH

This question always makes me laugh. The "famous influencer" saying this is using HGH himself. He just says it on podcasts because the establishment wants him to.

At therapeutic doses restoring IGF-1 to healthy levels as you age, no, you're not shortening your lifespan. Alex Kikel talks about how HGH helps restore thymic function. Your thymus shrinks as you age and HGH supports it.

Cortisol and testosterone

Multifaceted. Lifestyle first. GLP-1 peptides are great at bringing cortisol down. Mineral supplementation matters. But high cortisol is almost always lifestyle stress, so address that first.

Metabolic inferno stack

Carnitine, L-carnitine, SLU-PP-332, and retatrutide. That's the stack. I use all of these together.

HSV1 and HSV2 flare-ups

Thymosin alpha-1 should help because this is largely an immune modulation issue. LL-37 would be another good one to look at. No specific studies I'm aware of, but that's the line of thinking.

Peptides for neurodivergent kids and adults

For adults, cerebrolysin and oxytocin. For children, I've heard of nasal sprays of P21 and oxytocin being used with positive anecdotal results. I do not recommend this and I'm not telling you to do it. Just sharing what I've heard.

My take

Q&As are my favorite format because when one person asks something, thousands of others are wondering the same thing. The biggest theme this round was estrogen, GH timing, and how to stack things properly. Don't suppress your estrogen. Give HGH at least six months. Use taurine with GLP-1s. And do your own research on everything, including what I tell you.

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Full transcript click any paragraph to jump video

Hey everybody, this is Hunter Williams. I hope you are doing amazing wherever you were at in the world. Today's video is going to be a Q and A video. So I'm going be going through some user submitted questions now. First of all, thank you guys so much for submitting all the questions. And again, the link to submit a question to me is down in description box of every video, it's on all of the footers in my emails. Um, so thank guys, I am amazed at the level of quantity and quality of questions that I get. Thank you, guys because it makes my video so I actually can answer the questions that most people have in their mind instead of just trying to shoot fish

in a barrel type content. So that's what today's video is going to be. I've got like 45 here the last time I scraped them all out that I'm going try to go through. We'll see where this goes. I'll do my best. Some of these might be longer, some of them might shorter, but thank you guys so much. I've got a lot of catching up to do with my Q and A videos. So much, much long awaited video. Before I jump in, just thank guys for all the support. Don't forget to hop over to the email list. You can sign up for the Peptide Cheat Sheet down below and also to check out Foley Optimized Health.

It is the best private community on the planet to talk about all this stuff. behind closed doors, where we really get crazy. So I'm going to go through these and let's just rock and roll. First question, please do a video on peptides that could help with long COVID symptoms. Example, muscle weakness, fatigue, orthostatic changes, dysautonomic dysfunction resulting in LRDONLOS, POTS, and MCAS. Here's the first thing I would do whenever I hear something like this, I think immune system attacking itself. The first things is thymus and alpha 1. uh, KPV P VIP, um, LL 37, and then probably a micro dose of a GLP one peptide.

Then two, I'm thinking probably add in, uh. Like a BPC and TB 500 to just help with inflammation. Um, but I think those would go a long way to get you started and obviously get your hormones checked too. Cause typically there's some hormonal suppression that's going on, in that case. Next one, I would love to learn more on using which specific peptides are best for healing mold and the side effects of mold like CIRS and inflammation that results in our organs and even neuro like brain fog. I've been struggling with this personally.

So it actually would be very similar to the long COVID question. And then for, for the mold, I think you're probably going to have some more mitochondrial dysfunction than maybe like a long COVID person would have. So I would add an SS 31 and probably matzi together. Um, so, um, at the very least, if you are someone that's had mold sickness or mold poisoning or whatever, uh, you going experience some sort of benefit from all of those peptides together so.

I recently started taking metformin and feel great. I'm also on a small dose of desiccated thyroid. Saw a reel from Jay highlighting the importance of vitamin B12 supplementation with methormone. Could you clarify how much B-12 we should be taking? I currently inject 0.5 ml of B 12 twice a week. Is that adequate? Honestly, I don't know the dose, like how many milligrams or micrograms are in that. So I can't say if that's enough. Um, would say what I do is there's a, there a vitamin b 12 from global healing center I get only if I have an affiliate code for them. Probably should, because they have awesome products. But I take one milliliter of that.

I want to say that's 5,000 micrograms. Don't quote me on that every single day of B12. You want make sure it's methylcobalamin, not cyanocobalin. So methyl cobalamin. And that goes for if you're injecting vitamin B-12 too. Are there any supplements I would recommend taking alongside metformin? Testosterone and desiccated thyrin, I guess, but definitely B12. I think you'd be good with that. Next question, samireline versus tessamereline as related to anti-aging.

Tessamerline all day. Samirelines kind of worthless. It's outdated and it just gets promoted because certain influencers talk about it. Someone says, I hear you guys saying that red trutide is anabolic. I just started taking a few weeks and I'm actually eating at a deficit trying to lose fat. Not lost any weight yet. And I actually was having a hard time losing weight before I started. Taking it. Am I able to get leaner eating in a defecit on retrotide or should I be eating out of surplus or maintenance? This is a great question. Actually answered this in an email a week or two ago.

And the answer is, I think you could be at a maintenance or surplus and ready to true tide and still lose body fat. Now you might necessarily lose weight, but I because of the nature of it that you can eat like at maintenance for surplus. And because it's going to be improving your metabolism and also enhancing nutrient partitioning. If you're lifting weights, living in some control, doing all those things, losing percentage body fat while eating a mainstay surplus. And I know it comes down to like, Oh, it's calorie versus or a deficit versus surplus, like calories in calories out.

But what I'm saying is I think you can recomp with red shoot tied very effectively if you know what you're doing. Um, someone says detoxing your brain for mindless scrolling, peptides will help heal, improve the part of our brain damage from too much screen time being too connected. Yeah, I actually, This should be out after the video on Retatrutide or the cognitive benefits of GLP-1s come out. So I think retatratide does this because it's really like dulling the dopamine spike that you get from those.

Alternatively, if I wasn't able to do that, I would look at something like a 9-MEBC, which is supposed to help with like restoring dopamine signaling in the brain. I don't know too much about that one though, so you're going to have to your own research. Someone says, what are your thoughts on SARMS, which stands for Selective Androgen Receptor Modulator. So have you ever researched with them? If so, are there any that you recommend or are they a no-go? So I'll give you just why I don't make videos on sarms. I probably could, and they probably get a lot of views because all the SARMs, goblins, as they call them are out there.

They love stuff like that. But here's what I think. I think things have certain use cases. I Think even for select population SARMs potentially have a use case However, I'm not willing to go there and the reason is I've just seen too many cases of young kids that take them because a lot of them are oral products and They shut down their natural testosterone production Um, which again, isn't necessarily a bad thing, but we have to look at like the context of what's going on. And then, um, they also, uh, their liver enzymes shoot through the roof.

They have all this inflammatory cascades. So I don't know if that's the SARMS themselves, or if it's, the research company selling them, that are probably putting sawdust in them along with other stuff. But, I just don, it, It's just for me, and I want to go there. The reason is, is like I have, There are so many other tools in the toolkit to use that we don't need most of the SARMS for. I will say there's a lot of products that get lumped in with SARMs because SARM companies sell them and a Um, but they're not really a swarm.

So, uh, you know, like MK six, seven, it's not a really, a song. It's a grill an agonist that increases growth hormone, and it sold with swarms. Cause typically people that are dumb enough to take that also will take sw arms. Um. You know I'm not huge fan of them, But you go check out Tony huge stuff. I've done a podcast with Tony. Huge. He's the man. And I love that guy. He has lots of good info and he has a different opinion than I do, and that's totally okay. If you want to use them, go check out Tony Hughes' stuff. He had recommendations of how to us them and what you would use it for.

But for me, testosterone, some anabolic,s some peptides, they do the trick. I know within a certain range that there's lots evidence showing that they work and I can maintain my health accordingly. Questions, is a 10 ml vial of testosterone only good for five to six weeks? My pharmacy provides only one ml for this reason, this is true. Typically you'd use one mL if you're doing 200 milligrams per week of the testosterone, so that should last you 10 weeks, just depends on your dose.

This is a two part question. They said I had knee surgery for a fractured tibia bone when I was 13 years old. Fast forward 25 years, I now have severe stage of knee osteoarthritis. Will BPC 1% help to improve or reverse the arthritis in the knee? I think it definitely will. I always say with peptides it's relative to how much cartilage is there. So if it is bone on bone, probably not going to do a lot. Um, but what will help that I've seen is exosomes. So you can check out Dr. Jeffrey Gross. He has, um, a clinic called re-celebrate in Las Vegas and he's doing some pretty, pretty cool work with exo zones.

And the cool thing about them is I think they're more effective than stem cells and they are cheaper. But if you were to use exasomes and then come in with a peptide after, cause the exa zones help regrow the cartilage, you could then, get more effect out of the BPC because now there's cartilage there for it to heal. And then also TB 500 and GHK and PEG-MGF and growth hormone or growth peptide really do the trick. So I know it's not the answer you want to hear probably, but yes and no.

If non-FDA approved peptides are safer, better than prescription name brands such as Ozempic, Manjaro, et cetera. My opinion is, I think, pretty much anything out there that's in the research world is just as good as you're going to get from pharmaceutical companies, within 5%, I will say, of efficacy. So yeah, sure. You're gonna get a better response to the actual pharmaceutical stuff, probably. But is it like that? Is it worth the price? My opinions, no. Just know what you are doing, and if you were smart and you follow me in ways that you should, you'll know exactly what to do.

Next question, is it okay to take metformin 1000 milligrams daily split into two 500 milligram doses on an empty stomach while practicing alternate day fast and give it as typically recommended to taking food. Yes. And I actually prefer to it on a empty. Stomach while I'm fasting. You can take it with the food, it just slows gastric emptying. So you'll actually, if you getting bloating and cramping from met formin is probably because you're taking it food so if that's something you experience, try to to get on empty, stomach and see how it works.

Um, someone says, I have a friend who is an ex Marine and athletic weighing 245 pounds. He wants to get back in shape and reach two 15 2018, he had an irregular heartbeat underwent a heart ablation. but hasn't had issues since and isn't generally healthy. He's concerned that red tritide might affect his heart. What are your thoughts on this thing in advance? So it won't if you take two, three grams of taurine per day. So yes, I've seen this in multiple people now that I have coached. If you are using taurean, which everyone should be using two to three of grams tauring a day, in my opinion, you won' experience any of the tachycardia

that comes from GLP-1 peptides. I can't guarantee that, but with almost certainty, like I've heard people that had like really, really bad heart rate increases or tachycardia with red trutide, two grams of taurine gone in a day and then they're good. And a lot of times too, I think it's just because of the mineral nutrient depletion. Um, and also too probably something that's doing to neurotransmitters brain. Um, next question. I recently started using exogenous HGH about two weeks ago. Congratulations.

After completing a 12 week cycle of CJC and Impli and testosterone, I'm 45, six feet tall, 9% body fat and they're very optimized. Also on 225 milligrams of testosterone per week broken up into small daily microdoses. I've noticed a drop in my energy and vascularity right away. And honestly, I don't feel as exceptional as I did with my previous stack of GHRPs. I read and heard that HGH often requires consistent use over a period of time before the benister felt. To provide some insights on how long it typically takes for the benefits of HH to be expected. Planned to wait about eight weeks before I reintroduced GHRP peptides back in the regimen in evening.

While I do two IUs of a HG in morning. Thank you for everything you do. Well, thank you. It's a good question. What I would say is that One, HGH is so much more powerful. I think you're undergoing more of a cellular remodeling process that is causing you to be tired and probably feel a little bit more bloated. That being said, that usually goes away after I would say like five to six weeks.

And I will say anatomically speaking, when we look at the structure of our body and our muscle, did the benefits of growth hormone really kick in around six months? kind of similar to testosterone. And so if you give it six months, you're going to look back and be like, Whoa, I noticed a difference. The only other caveat I'll add to that is if it's pharmaceutical grade growth hormone, meaning that if Gotta be careful because the response is always at the same and there's gonna be more like side effects. So that's all I'll say, but I will say give it a little bit of time and you'll be okay.

And you're gonna throw back in the peptides. I like the HGH in morning. Two I use the morning and then take your peptide at night. That's actually what I'm doing right now. It works really well for fat loss and just sleeping really too. Oral testosterone used to start testosterone replacement therapy while maintaining fertility and some natural production, instead of having to take injectable testosterone, HCG, and HMG for a limited cost.

I'm just not a big fan of the oral testosterone. One, because I don't think it's going to be strong enough to get you the therapeutic effects testosterone on the body. Alcohol, too, I think is probably taxing on liver, so I would stay away. From that, and people are saying, well, yeah, it's not as strong, so it doesn't suppress your fertility, but I just think go with the tried and true that we know works. Next question, is there a valid use case for low level HGH, which is one and a half to two I use daily with testosterone? Yes, I think so.

I'd think if you take one to I used in the morning before your fasted cardio and take I've been doing two milligrams of Testmerone at night. You're absolutely going to have a good response to that. And I won't stay on that for longer than probably like eight to 12 weeks, but it does feel really good. Then I'll go back to just doing HGH, you know, one IU in the morning, One IU at Night. I'm always kind of like playing with that to see what works best. But yes, absolutely. The second part of that question is that there's any possible synergy on total GH production there for someone 50 plus who does not produce it FDH or would

Tessa only help from the visceral fat loss perspective? I think it would help them both. Like you just have to realize like it's not that testosterone is not going to do anything the older you are, but the order you're, the harder it is for your liver to be able to enzymatically convert HCH and IGF and for like the natural process from your pituitary to basically be stimulated to it. So it doesn't work. It just doesn' work as well. 40 versus 50 versus 60 versus 70. You're just going have a less pronounced response to the peptide. But some people still like. and it still can do things for you. So, good question.

Next question, so I recently discussed disked thyroid with my optimal health doctor who also prescribed my testosterone. I requested either 30 milligram or 60 milligram, but she prescribed 15 milligram of MP thyroid, stating 30 or 62 high of a dose. Since you take six milligram daily, I mentioned that anything under 30 may not be effective. How would you suggest I express my desire for higher dose while respecting your expertise? 6 foot 200 pounds currently is sitting at 9% body fat. Um, I would just go get it myself and do what I know I want to do. So that's what you can do and obviously I can't tell you where to get that or recommend in the comments or anything like that.

But if you're smart, you'll know where Are there any peptides to avoid when doing a parasite cleanse? And what do you take for a parasite cleanse, for example, ivermectin? Yeah, Ivermectin is great for parasite cleans. LL37, BPC, TB500. Erasotide is another gut health peptide. KPV, Tributrin, those would all be good ones to take. So thank you.

Can you do an episode for older females who actually are hormonally optimized and on desiccated thyroid for that same period. I follow a carnivore diet active and want to maintain muscle strength. Uh, I think the first thing is to help support muscle growth and muscle. Gotta eat some carbs. Probably should do like a different video about that, even though I'm like, not like diet guy. so to speak, about the importance of carbohydrates. And now we have tools on our belt too to really mitigate any of the damage from carbohydrates, I don't think there really has to be damage if you're eating insulin controlled, but anyway.

Currently on Tesmorella, when I'm done with the current cycle, can I start AOD 964 immediately after the TESSA or do I need the eight week cool down period to start the AOT? No, they're fundamentally different. So I would absolutely, I could, even use them together. I've done that before. Um, so yeah, you could definitely, um, start AOD right away. Um, next question. I've just finished one cycle of red and Tessa, and I'm super happy with the fat loss. Uh, 50 years old, perimenopause, previous insulin resistance. Following up, I tried a couple of days of one IU of GH, but I got scared how hungry and foodie it made me feel.

So I stopped afraid how to put the weight fat, weight, uh, fat I'd lost back. Any advice? I am already on metformin, dihydroberberine, hormone optimized desiccated thyroid. Um thank you to Jay, you and Taylor. Want to use my HH for all the amazing benefits. but it's just making me too hungry. Or maybe I should wait until I cycle it the right way again, any input. Yeah, so this is actually what's happening when you start the HEH is so powerful at regulating your metabolism and increasing your metabolism that you get hungrier. So if you don't have Ritratide with it, which I think It's fine to take without, of course, but when you are increasing your metabolism,

your body's going to be hungry more. So one, listen to your buddy. And two, if you can handle it, you now can eat more carbohydrates to synthesize muscle, which the HGH is going allow you to do. But if feel like you have to, especially if your fat and lost weight, sure, add in a GLP-1 peptide that can help do so. Just understand that when your your gets hungry for a reason, it's sending you signals. Sometimes that's good, sometimes it's bad, but if it is a good reason because your metabolism is higher and it needs more food to grow muscle,

then I would listen to the body. Someone says, did Eli Lilly invent the active ingredient trisapatite? Cause so many people give them credit for creating this. So I was just curious to actually research and create this, or they just researched the dosages and health benefits we can gain off of it and have the money to do the research of bringing it to market. Yes and no to both. I'm sure there were people out there that were using it before they came out with it, but a lot of these things are like done years in advance and then they come to the market and it's out. There.

Um, next question. I've been taking Regenishred aka SLUPP332 for a month and I love it. Plan on taking the 500 microgram a day for two months. Can I stay up for longer or should I come off of it for 2 months before cycling back? Um during the months I'm off SLUP, do you recommend I incorporate another mitochondrial peptide for the time being? Yeah, I would say so. Um I will check out the podcast we did with Alex Kickle to which we're going to be doing more of those. Um, and I would say yes, because like if we're constantly overspending the mitochondria, there's no like recourse for that.

And so whether it's five days on two days off or like one month on one, month off, I was on it for five months and i've been off of it. For like two weeks now, i'll probably go on another week or two, just take like four weeks off. So it should be up to you. Um but just be conscious that you don't want to like over-spend the Mitochondria. Um, is there a scenario where daily pinning HHH at low levels would work synergistically with testosterone? I think I already answered that question. Um. Yes, you can definitely do that. And then, uh, see what happens guys is these questions.

There's whenever one person has a question, there's really like 10,000 people that have that and that's why I do these is because two different people ask the same question So like, if that's something I'm like oh man, that like a signal to me, like I need to talk about that or figure it out, you know, it's like how to communicate that better. So thank you. I was watching a certain podcast that talked about gray marker peptides. He discusses major issues in cleanliness and purity. It has lipopolysaccharides and serious life threatening consequences of taking these peptide not for human consumption.

I've seen a different video of a woman saying heavy metal poisoning that happens with reservations peptids. How do I vet a peptid group? I have PCOS, perimenopause, pre-diabetic and massively overweight. Also brain fog, loads of inflammation, hard time losing weight, metabolic issues. I've been dealing with bad doctors for seven years, I'm on some HRT now, and I must take care of myself. I have to start peptides. No, you have too. Be in control of your life.

Just take everything you hear from people with a grain of salt, including myself. So like if I promote something, go out and do your own research and put it to the test. Like if you here something from really big time influencers that trash peptides because they make money on selling athletic greens to you and they would rather you buy athletic Greens and have something that completely revolutionize your health. Yeah. Then like put that to test too. I don't want to go off on a tangent, but if your sourcing your peptide from reputable research companies, in my opinion,

you have nothing to worry about. But you just have to do your own research and be an active agent and take an act of role in your health and do you own your research. So, interesting your thoughts on Hypoxin and Bono Marlowe, which are the bioregulators for red blood count optimization. I don't know much about Hypoxin, but I do know Bonomarlowe does really well, so you can check that out. from the company I work to buy regulators with This is a good good question slash comment to estrogen and it's conferred benefits of men I love you could

do a dive deeper into a previous mentioned other videos on its relation to IGF one conversion protective benefits optimized levels And they influence lower body levels have on this quantity of the body. Thank you for you. So this is good point basically The less fat we have on our body, the lower we convert testosterone into estrogen, meaning that we aromatize less of our testosterone and estrogen. Now for guys that are really lean and I've done this myself because I'd been like really leaned at certain points in my life, my estrogen goes low because i don't have enough aromatase enzyme because I don't have enough body fat to convert the testosterone estrogen.

My estrogen is low and then you have no sex drive and you, uh, have a really bad mood and don t feel good. And that's why I dont recommend that you should press estrogen, um, there's also this thing that I do not know cause I'm not a scientist, but the probe myth says that if your estrogen is too low, that it impairs the conversion of growth hormone into IGF-1. So you could be taking all this growth hormones, but if you're estrogen's too lower or you are suppressing your estrogens, it's not going to do as well as it would if the estrogen were high enough to support the So I'll need to do more research on my own end to that and who

knows what's out there. I think at best, even the smartest people in the world probably could just speculate right now until they could really find out. But it definitely is a thing. The leaner I am, the less estrogen I'm going to have in my body and the more of a chance that I will need supplement with estrogen exogenously. as a man or depending on like whatever I'm doing with my hormone. So just be conscious of that. I don't think it's bad for men to take estrogen in certain cases where it is warranted to put you in a therapeutic range to which you're going to get all

the health benefits of estrogen, which include namely cardiovascular protection and neuro protection. Someone asked me about the glow peptide combo GHK TV 500 BBC one seven. It's amazing. Works great to heal injuries. Or if you just want to take it for overall inflammation and skin and hair health. Um, Would you consider doing a video on how to read and translate a male hormone panel tests and maybe explain approximations on ranges of where numbers

should be? I definitely could actually just got my blood work done today. So maybe what I'll do, if this gets like enough likes or comments, or I just get like, enough feedback from people, I could pull up my own bloodwork and go over it. I wouldn't mind doing that. It's kind of hard to say though, cause like everyone's different. Like it's very nuanced, but I can definitely do it for myself. If that's something people would be interested in. Um, benefits of stacking GOB1s for optimal gains. Um yeah, if I were to stack any right now, it'd probably be like, If you don't have enough appetite suppression from Retta,

you could do a little bit of Cagrillian Tide, which I haven't talked about that much. Or you can do like half and half Church Appetite and Retto True Tides. Peptides for prostate enlargement, definitely check out Bioregulator for that. The main one would be Libidon that you would want to use. There's also Prostomax, which is supposed to do really well, Which is like an injectable air regulator I've seen. I just haven't used it, so I can't really speak specifically to that one. Is Regina Shred the same as Ban15?

No, but stay tuned for more info about Ban 15. And I'm kind of researching that in the background right now. I have clinical SLAP tears in both my shoulders. Recommendation, any peptide that might work. Um, I'd say check out the exosomes. Like I mentioned, PPC one 57 TB 500. Just see how it does. It's like, you can't promise anything. Someone says GW501516, which is carterine. I saw it on TreadX from BioLongevity and loved it.

Here it compares mechanistically with L-Carnitine as well as potential for stacking with SLU and RetroTide. All of the above are good. So I use carteryne. L-Carnitine, SLUPP332, and Retatrutide. That is a metabolic inferno stack right there. So good stuff. I don't need to go into like all the dosages of it now, but those are all good things that I would use and have used and do use together. Um, I recently heard a famous influencer.

They said the name. uh, talking about by using HGH, you're burning the candle at both ends because anytime you were forcing growth, your also forcing going to shorten your lifespan. Is there any basis to what he's talking? It seems like you and Jay have a totally opposite view. I do. And the reason I'm laughing is cause I know for a fact, the guy saying is using HDH, but they go on podcasts and they say stuff like this. Cause they like the establishment wants them to say it, But it's just hilarious to me. Like, If you're using it at therapeutic doses, of course not.

If using to restore IGF-1 production to a healthy level as you age, course, not, but I don't know why people out there are clowns and literally will be doing one thing and then tell people, oh, you are burning the candle at both ends, so it's pretty comical to me. No, and to the notion of HGH, Alex Kickle talks about this. is how it like helps restore thymic function because our thimus shrinks as we get older and helps to restore and support that.

So no, I don't agree with the famous influencer that said that and you could probably look in this fridge right now and there'd be like 10 pins of growth sitting in. How to control cortisol levels and impact on testosterone. That's a multifaceted approach. Obviously you got everything you can do from like a lifestyle standpoint. And then also to, I think a GLP-1 peptides, and I've talked about this, are really big at bringing cortisol down. Obviously, mineral supplementation is key, but a lot of times cortisol is up because of stressful lifestyles.

So it's very, very rare that you have someone that is not stressed out that has high cortisol levels, unless there's something weird going on. Um, what happens when you block estrogen to a woman? It is not good. Get some stuff out there for women and post-menopausal woman. There is such a thing. I actually have a video. It's called testosterone therapy for woman and I talk about that, but, um, we're going to find a book on peptides and what is for what? What do you recommend? Um. You can check out Jay Campbell's book, uh, obviously my YouTube channel.

Um so yeah, check that out. But, blocking estrogen in man or women, a man, or a women is bad. Here's another Sarah Morellin question. So someone says, um, I'm new to your podcast. I haven't found any information on Sarah morellon. It seems to be popular, you know, like your opinion about it. I just person at a max and add a link and there's not much info on it.

It'd be great to know. Yeah, I should do that because those are a little, they're pretty cool little peptides. They're harder to find. Um, there are just no tropic peptide. I think probably people will respond better to them than, um, see max in saline themselves. Next one, NA931, which is basically retitrutide, meaning that it has GLP1, GIP, glucagon, plus an IGF1 agonism. It's potential long-term use without it, with it being a small molecule, not a peptide. I'm really excited about this.

And if you stay in communication with me and just continue to follow me, be on the lookout for something that potentially we could release this year that I'll just say we'll be similar to something like this. Um, estrogen conferred protection for men, any possible relation to why we should avoid AI's while on TOT. Well, it does seem like the people are starting to like pick up at least the that are sending me questions, um, that we never want to suppress estrogen. And I'm not saying you want like 200 estrogen as a man, but we don't want it to press estrogen, especially when we're suppressing in the brain.

It does really bad things in That's why I would stay away from our own taste inhibitors, not only because of suppressing estrogen in the body, but also to like what it's doing to the expression of the brain. So yeah, I think inhibiting estrogen is bad as inhibitting DHT. The new peptides that could help reduce or eliminate the expression or flare up of the HSV1, HVS2. Current stats are 80% of Americans have HSv1 and 1 in 6 have Hsv2, an edgy subject no one wants to talk about.

Yeah, it's true. No one does really want to about it, but I would say thiamin-sulfo-1 probably would help again because From my understanding, this is more of like an immunomodulatory thing. And also I think LL37 would be a really good one for this. So who knows? I don't know specifically if those have been shown to help, but that would kind of be my line of thinking. Peptides to use for neurodivergent behaviors. I'm not going to say the A word. but neurodivergent behaviors and communication. So it kind of depends on you for a child or an adult. For adult, I would just go cerebral liason, because I think that's going to help also oxytocin.

But for child, you can use these in nail sprays for compliance. And I don't recommend this ever. This is something I heard. I never recommend doing this. take that with a grain of salt. But nasal spray of P21 and nasal spread of oxytocin has been shown to help. And I've heard anecdotal evidence from people that have messaged me that has said that it's helped. So that is the final question. Looks like we're ready 32 minutes. That's the Q&A for today. Hopefully this was helpful to you guys. Again, don't forget, check out the link and you can go submit.

There's a URL that you go to submit a question to. It's in the description of every video that I publish and also on my email list. Thank you guys so much. Hopefully this was helpful to you, guys. And don't forget, be signed up for the email list because that's where all of the stuff that I kind of had to self-censor today happens and you can find and goes down. So, appreciate you you much love and I will talk to the next one. Peace.