Peptide Q&A · March 2025

0:10 Hey everybody, this is Hunter Williams. I hope you're doing amazing wherever you are out in the world. Today is the March Q and A video. So after right around a month of the last Q&A video, it is time to come back with an update. And it's also my email newsletter in the footer.

0:40 My goal with that is to take all the questions or video suggestions or even things you just want to send me. If you want send a study or some cool peptide or something you found like that. I have people do that all of the time. So send those to that little submission box and I'll get to those and then I compile them and put them in this video. What I'm doing now is I am doing them by category, so obviously there's probably some overlap between categories, but in the best way I can, I take them and put them in categories. So just for the purpose of watching this video, it's cool because I kind of address questions that are grouped together by a category over time.

1:16 These are the questions for last month. I was super excited because there are some really, really good ones. There are more elementary ones, which I'll address, there is some other really really What's cool for me about these is just getting to see the evolution of the growth of audience and the questions and how much better they get over time. So that signaled me that humanity is moving in the right direction and all of this in this community are doing a good job of kind of going along. Without further ado, I'm going to look at some of these questions now what I do I don't share my screen with these because basically it's just a Word document

1:47 and you wouldn't probably be able to read it So I'll have slides or anything like that for this one. So it is just going be me answering questions. Let's get started. I have the first group as performance and recovery. So let's go over that. First question is five amino, one MQ, liquid versus pills dosage comparison. And so I think this person means the injection versus Pills to which I would say for pills, if you're doing five, amino one,

2:17 M Q, you can start with 50 milligrams and you go all the way up to 150, 200 milligrams, depending on your tolerance and how large you are. Usually, you're going to stop out around 200 mg. I don't think there's any added benefit to going over 200mg. Now, I have found the injections from anabolic synonymous, aka AA, or whatever you want to call it, which you can find on the email list, to be far superior to the pills in my experience. And the injections, I'll use 500 micrograms to one milligram per day. So if you get a 10 milligram bottle, you add two milliliters of water into it, and then you take 20 units for one milligrams a day,

2:52 10 units from 500 milligrams today. That's what I would do for that. Next question, peptide and supplement protocol for endurance events of 50K, 50 mile, 100 mile. Wow. Kudos to you. Whoever asked this question about 50 miles or 100 miles runs at is crazy. I could, I guess, if I tried, but I have no interest in doing that. But that's awesome that that person has this as a goal. Again, just don't make any illusion or delusion that it will be good for your health because it won't.

3:22 If I were to do this, the first thing I would do would be injectable L-carnitine. That's going to be huge, 500 to 1,000 milligrams per day. Albuterol, usually like five milligrams, per session. or endurance event, I think that's going to be good. Obviously, you're going need a lot of carbohydrates throughout this. I would be using testosterone probably in some neighborhood of like 250 to 300 milligrams a week. If you go too high on the testosterone, it can kind of maybe make it a little bit harder for endurance events because you might be carrying a bit too much

3:57 mass naturally. From there, there's a lot of different things that I could probably go into and do a deep dive video on about this, but those are a good start. I think ARA290 would probably be a Good one. That's kind of actually like an alteration of EPO, which is what Lance Armstrong and all those guys were using back in the day and probably still use, otherwise known as blood doping. Trying to think, Matzi would be really good. I think Matzie helps with endurance.

4:27 SLU PP332 with BAM15 would help with Endurance. So those are good starting put. And then just the last one to close out would Be Carterine GW501516 would a really Good starting point. That's what I would do. Then obviously focus on your training. A lot of the endurance side of things is going to come from being able to use carbohydrates effectively too during that. Not that I was never an endurance athlete, but even just playing football games where you're on for four hours at a time. You've got to have carbohydrates when you're doing that. So, SOUPP332, injectable versus oral, which is better.

5:01 Actually, you haven't used the injectible, but for people I talk to, the oral and the injected will actually, in this case, are pretty similar in terms of the benefit that you get. I know the injection was out there, I've just always used oral. Next question, best peptides for jujitsu performance and endurance and recovery? I would say for, excuse me, for jiu jitsu, obviously make sure you're hormonally optimized. I think for performance in the ju jutsu realm, kind of similar. You want GW501516 is going to be good.

5:32 Inject about all carnitine, 500 milligrams to a gram. Injectable l-carnitine is going to be really good. You can even get some of the aminos from AA, like Ultra Instinct, to kind of help with focus and movement during that. I think tiacrine would be good because performance, you want your brain on fire, and that's going help there. Those are a good starting point. With it, recovery wise, I definitely think all jujitsu people because of the impact to the head and the body, BPC 157, TB 500, and probably even Cerebral

6:06 Iodine once a year or so, just to help with the brain impact from the concussions. And even if you're not getting concussion, your body's getting slammed around a lot, so that can be dangerous too. In regards to brain, because the brains still getting rattled around from impact. SLU PP332 dosage for endurance, when to take it? I think probably the sweet spot is going to be 500 micrograms to 1,000 micro grams or one milligram for people. I don't think you get much more endurance benefit and it could probably go in the reverse direction in terms of impairing performance if you go too high.

6:40 So I'd think 500 to 1000 micro-gram for SLUs. Peptides to help with lactic acid buildup and gas tank for jujitsu. Kind of the same thing, like I said before, you know, You'll definitely notice things from injectable carnitine, GW501516 aka carterine and I'm trying to think if I am leaving anything else out for endurance. I think Albuterol would also help with Jiu-Jitsu for the endurance as well. So, kind of similar.

7:12 Best stack for pre and post training for Endurance and Performance. Kind of, similar to everything else I just said. Post training you would probably want. BPC 157, TB 500, I really like Growth Hormone at night just to help the recovery. My recovery is so much better. Especially, too, because I've been using an aura ring lately, and when I use growth hormone after nights on training, my recovery is so much better. One thing, maybe two, to add in that I just started doing again, except in cycling it, is low-dose naltrexone.

7:42 That really seems to help with recovery for me. I sleep better, I know it's making the peptides and the hormones and everything I'm using work better so it just seems like I slept so better when have low dose naltrexon. Now, whether it's that or the fact that it is making everything else work better, I don't know. But it does really, really seem to help with the inflammation cascade that comes from training excessively because I still do that on a regular basis. Let's move into some peptide dosing and administration questions.

8:14 Best way to inject intramuscular versus subcutaneous for different peptides? I would say most peptids, subutaneous is what you want to do. I think if you get a bad reaction from the peptid, meaning like an allergic reaction, intra muscular can be very beneficial. I actually should probably do a whole video on that, but subcutaneous for almost all peptides. Now, if you are injured and you're using BPC and TB 500, you want to inject, You know, could still do sub cutaneous around the injury, But sometimes it's better if go to the muscle depending on the nature of the So you could do that there.

8:45 But yeah, I think that the only time you would explicitly do intramuscular is if you are having a bad reaction or if it was an injury and the rest are just going to be subcutaneous. So I'm sure there's some other use cases off the top of my head I can't think of. This is actually a good question. Not something that a lot of people will struggle with, but how do you, how did you inject if you have very little body fat left? So what you want to do, I don't have a needle right here, But if I take this pen, if this is my belly, most people can just grab belly fat.

9:17 and then stick it in the belly fat. If you don't have a lot of belly to grab, you want to kind of take the needle and stick down at an angle like this, because that way you're actually getting into the little layer of subcutaneous fat you have. So instead of like injecting straight into bellyfat, like most people can because they have enough fat, and I apologize if you are listening, go down it like a 45-ish degree angle and kind go in that and it makes it easier if your super lean. That's the best way to do it if really lean and inject. Knock the camera a little bit.

9:51 Mixing instructions for Penielon, 20 milligrams of two milliliters of water. Yeah, you just add two million water into 20 milligrams. It's now 10 milligrams per milliliter. And I would do one milligram at night. Those things kind of all over the place, but I will just start there and see how you respond and do that for 20 days in a row. So one bottle is going to last you 20 years in row and you would just take 10 units if you put two millimeters of reconstituting and dosing of a blend of GHK TB 500, BPC 157. Typically what I've seen is that these come in a five to one to, one blend, meaning five, excuse me,

10:23 it'll be 50 milligrams of JHK, 10 milligrams at BTC and 10 of TB500. So what would do in that case is I would add two milliliters of water to the vial, and then I would take 10 units. And what that's going to do is give me 2.5 milligrams of GHK, which is a good dose, 250 micrograms of BPC and TB 500. That's a great dose and you'll be really off to races there and just use that five days on, two days off for about eight weeks. There you go.

10:54 Preloading multiple peptides in the same syringe, is it safe? It depends. I actually have a video on my channel about which videos you can and can't mix with peptides. So to sum up that video, the answer is basically if it is working on the same pathway, then you're probably okay to mix them together in the syringe. If they're completely different peptide like a GLP-1 and a growth hormone peptid, you don't want to make those because they are working two different pathways and then when they delivered, You know, like at least from a practical standpoint, technically you could maybe have some,

11:25 you know basically cross reaction where they're not working to the best of their ability. So I'll say that. How to use and convert doses with the auto pins. The auto pens are actually very, very easy to us in terms of the dosing. Basically you just mix the peptide the same way you would normally and you put it into the cartridge because there are three ML cartridges and then the ticks on the auto pen equal one unit on your insulin syringe. So if you wouldn't normally do 10 units of peptides, you'd just turn the autopen to 10 and that will give you 10 unit.

11:55 A lot of people overcomplicate that. It's very simple. However many units you do according to the Peptide Calculator on an insulin Syringe is the number that you turn it to on autopens. If you were to do ten units, turn to ten. 15 units to 15. The dose is just calculated the same. Do the thing that you would normally do for your regular peptides and then just translate that unit measurement in terms of the units that your dosing into the pen and you turn that and eject it. So if there's enough demand, I could make a, probably only be like 10 minute long, but let me know in the comments if you'd like to see me doing an auto

12:30 pen video and I can probably do that. Hopefully I wouldn't get in trouble. Blood test to monitor while using peptides. I don't think there would be anything that I would look at that would different from a normal blood test. So the best blood tests I recommend, you can go to privatemdlabs.com slash JC. He's got one on there. And then the one that like is from life extension. Don't have an affiliate code for it. Probably should. It's lifeextension. com and then just look for the male or the female elite panel. And I think it's like 575 bucks and get it done. That is like everything.

13:01 It's a really comprehensive one. So that's what I like. I mean, it doesn't have everything, but in terms of blood palates, really good. Moving along, let's go to peptides for injury and pain relief. Well, some of these got mis-categorized, But anyway, Let's just talk about some peptide because that what you guys want to know, right? How to mitigate testosterone water retention. it is really tough. A lot of people are just going to get water retention on testosterone. Regardless, sometimes it happens right away. Sometimes it doesn't happen for five to 10 weeks in.

13:31 The best thing is to cycle it. So you don't really want to use it more than eight to 12 weeks at a time. Not because you can't, but just because. You're going get a water attention and then most people don' t want it to look like they have water retention if you're trying to lose fat, right? So I think relatively to relative to how lean you are, you will notice the water tension more or less. Um, the leaner you, are the probably more you' re going notice that water So I would say for mitigating water retention, one, if you do five days on, two days off, that's going to help because you're taking two day off or even if did every other day.

14:01 So if he did testosterone, 2 milligrams, took a day, off did another two milligrams kind of the same way you could do growth hormone. If you were trying to mitigate water attention, I think then from there you doing what you can from a dosing standpoint. And then you say like, okay, well look at my lifestyle. Am I doing fasted cardio? Am my living insulin control? And I'm doing all the things that are going keep water, retention off anyway. And in some cases you are and you'll still get water retention to which point you can just say cycle off. But you know, you could do to, uh, I've done this past. You just take one week on and one weak off, and then you take on the test from Rellen.

14:32 And you get the benefits of it. Then you kind of maybe notice start to get a little water attention. They just took a week off and they're good to go. So, there's no perfect answer for that, but that would be my best one. Next question, peptides for lower back pain and localized injections. Yeah, I think BPC, TB 500, PEG, MGF are a really good start. Depending on the nature of the backpain, sometimes peptide are going to do anything because if you have a bone-on-bone injury, it's really tough for peptidies to anything in terms of regrowing the tissue. You can look into exosomes and stuff that would help regrow the Um, but I think the same that would work for knee pain or shoulder pain,

15:07 or whatever. I've strained muscles in my back before and I'm telling you, I put, you know, 500 micrograms of BPC, five hundred micro grams of TB 500 and 250 micro-gram of PEG, MGF. Stuck it right in the muscle in back right there. And because it was a muscle injury where I was having like muscle spasms, bam, like in a day, it's crazy how good it is. So, uh, that's what I would do. Best peptides for tendon and ligament injuries? Yeah, same thing. BPC, TB 500, PEG, MGF. Then you could add in GHK. The thing that sucks about GH K is it just kind of burns.

15:38 So depending on where and when you're injecting it, it burns so for instance, I'll just tell a brief story. Uh, two or I think it's been three weeks ago. Now at this point I dropped a 45 pound weight on my foot at the gym. I was going to rack it and then like I wasn't paying attention and I, Didn't have it all the way on to the pole that I was racking it on and so when I went to go push it it wasn't all The way and then it like bounced back off and just dropped on my foot now luckily it was only probably eight or 12 inches

16:08 off the ground, but still it, it hurt really bad. And immediately like my shoe got covered in blood and it got everywhere and I was black and blue. I don't think it ever broke, thankfully. Cause I still couldn't move it all the way, But it was just swollen really badly. That was injecting BPC, TB, PGMGF, and then also GHK and the GH K would literally burn so bad around the toe. Now, some places you inject, doesn't burn as bad other places it does. but it burned so bad it kept me up for a couple nights where I would wake up every other hour because it was throbbing from the GHK injections.

16:40 I dropped the ghk injections just kept with the bpctb 500 and pgmgf and it ended up being fine. So peptides for nerve pain neuropathy the go-to one's going to be are 290 you could also use bbc 157 and tb500 together alongside the are I wouldn't put them in the same syringe Those are going to be a really good start. You could also potentially look into thymus and alpha 1, 2, because there's going be some healing that would probably come from inflammation there. So those would be my starting ones.

17:12 Is a BPC-157 cream effective for sports injuries? I don't know. I've never had a bpc-147 Cream. But if you go to BioLongevityLabs.com, we have a cream called Bioregenics that is better than a BBC cream if there was one for healing sports injury. So that's what I would try. Let's move into some muscle building questions. Peptides for a 20-year-old baseball pitcher, are GH peptides safe?

17:42 Yes, they're definitely safe. If your child was 20 years old that you could use for baseball pitchers, that would be totally fine. I would have no issue with that. People that are administering growth hormone itself to their teenagers that our athletes to help them with growth recovery and performance I don't know that you get that much of a performance benefit from the growth role, but you definitely get a recovery benefit From it and then this same person also has peptides for muscle growth at age 20 test morel and CJC Yeah, those are good. Just always remember that a lot of the muscle building comes from their levels of hormones in their bodies so I would look at injectable carnitine alongside those.

18:19 I'd look maybe at something like a testolutin alongside that's a bioregulator that helps increase testosterone naturally. It's not going to do the same thing that testosterone does, but it's better than nothing. That's what I pair with those to get the best bang for your buck. How to cycle off Ipamrelin and the best replacement? I would typically use Ippamrellin for 8 to 12 weeks and then I'd come off of it. And then the replacement, if you wanted to use something else in that time, testosterone, you could use CJC or you can use even something like an IGF-1LR3 for 4 to 6 weeks, and take Iphamrelin off.

18:51 I would actually probably lean on doing like the IGF because it's working completely different than the growth hormone sacretagogue peptides are. And then you can use that for 46 weeks and then go back on the Growth hormone peptide like ipamrelin. So now that I think about it, that might be a good thing because IGf is shorter, last shorter in terms of like how fast you put up tolerance to it. Then you could use for four to six weeks, take off and go on your Growth Hormone peptid, assuming you didn't want to use Growthhormon itself, which will obviously be better than all those.

19:22 Next one, microdosing MOTC with retitrutide, optimal dosage. I actually wrote an email about this a few weeks back, but I would use 0.5 milligrams of retritrutite three times per week. And that would do one milligram of Motsy per day. That's a really good micro dose. Then you can titrate there. You could probably go up to two milligrams MotC per and do that five days on two days off. Eventually get up two, two and a half milligrams or retrutides split into three to four doses per That's what I do and they work really synergistically

19:54 together for sure, especially if you're using SLU and then BAM-15 and some of this other stuff we have access to now. So the best stack for muscle gain in a 45-year-old woman on turzapotide? First, I would say testosterone. My guess is a forty-five- year- old woman could be either perimenopause, postmenopaus, maybe you are still premenapause. But I'd say look at your testosterone, that's going to be the ultimate dictator especially on GLP-1. a GLP-1 and they are hormonally deficient. Most people are hormoneally-deficient and so the GLp- 1 just kind of exacerbates that because you're in a caloric deficit,

20:28 because they're not eating as much, and then you kind-of notice how bad it really is. So I would say testosterone, the first thing, then obviously too, I think it should be standard practice to prescribe a growth hormone or growth-hormone peptide alongside a GLP-1. So for a woman, I would say Ipamerelin would be something you could at least add in to help support some of the muscle maintenance or muscle growth, assuming you're lifting weights with the trisapatides. That would the first thing I'd say is check your testosterone levels, use growth hormone or a growth-hormone peptide.

21:02 Next question, kind of similar peptides for building muscle in adults 55 plus. Again, the answer is going to be testosterone. This is actually something that I think if you guys can think about muscle building in this way, there's really three ways to build muscle. In the body, you have the testosterone pathway, which is for men or women. both for men or women, you have the growth hormone pathway, and then we have insulin pathway. Now, what can we do for testosterone? Obviously testosterone itself works really well. We can throw in other things. You can through in anabolic steroids. That's what bodybuilders would do.

21:32 They'll take their testosterone up to the max dose they can tolerate. Then they'll throw some anabolic steroids on top of it, which are really a lot of times DHT derivatives. Maybe they are, maybe they aren't. Or they will throw on oral steroids or whatever it is. Then they look at the growth hormone pathway. So growth, hormone itself is going to be king, but you could use ipamrelin, CJC, tessamrelin, IGF-1, any of those things to help assist the Growth Hormone Pathway, because that's going be crucial for building muscle. And then lastly, we have the insulin pathway, so bodybuilders will use insulin itself. However, you can use something like a microdose of erythritide to help with insulin sensitization, to helps with nutrient partitioning.

22:08 You could use something like metformin, you could do something dihydroberberin. And the reason we're using those, most people wouldn't think of those things as muscle building agents. What they do is they help drive the carbohydrates that we need into the right places and partition the nutrients in the most effective way. So we have the testosterone, we the growth hormone, and then we an insulin or an Insulin-Mimetic. A lot of times a GLP-1 can act kind of act like an insulin mimetic, meaning it allows us to partition the nutrients in the right manner as we're eating carbohydrates. And remember, what does this all go back to? Well, it comes back how well we can tolerate carbohydrates to build muscle.

22:42 The rate limiting factor for muscle building is always going to be the amount of food you can take in. So many people don't realize that you have to eat carbohydrates, one, period, because we have a lot of carnivore and keto people out there, but you gotta eat carbohydrate if you wanna build muscles. Then also two, in a process of eating those carbohydrates, you have to be on a caloric surplus to able to put on muscle because the body's not going to accrue muscle tissue if you don't have enough calories to fuel the exercise that it's doing. So that's why we need that insulin pathway.

23:12 And again, bodybuilders will use insulin itself. That would be like a very advanced thing that you could do. But to the average biohacker, or you can use metformin, dihydrobermarine, Jardience, a GLP-1 peptide to help with that insulin pathway, to the insulin sensitization that we need in order to build muscle. I think when we look at peptides, it's so easy to just say, Oh, I'd love to take this peptide and it'll take the training that I'm doing and then just amplify the results and make me automatically put on muscle.

23:43 In some cases, is that true? Yeah, maybe. Maybe like newbie gains. But I, think in most cases we got to be working all those pathways about muscle and if you're not doing something to address one of those, whatever it is, you gonna be kind of tough to build muscle is not just the peptids. So let's talk about some GLP-1 peptidies. First question, should you cycle off GLP-1s or stay on long term? So this is, it's kind of a loaded question but it is a good question. At high doses, yes, you should cycle of GLPs. However, the deeper and deeper I get into this game, whatever this The deeper and deeper I get into the game, the more I realize we could potentially blast

24:22 and cruise GLP-1s, meaning that we can use very tiny microdoses. And if I'm talking about Reddit True Tide, I am talking maybe half a milligram a week in what would be considered my cruising phase, and then for a fat loss phase I can go up to two, two and a half, maybe three milligrams a day on the higher end, or higher depending on how bad the fat-loss or the body fat percentage you have is to address more of an aggressive fat loss phase. So the way I kind of am shifting to think about this is blasting or cruising.

24:55 Throughout the year, staying on a really low dose. And then when I need to move into a fat-loss phase, I can go up. What's going to happen is during those times where I go, and again, we're not talking about huge doses here, two to three milligrams a week, When I go up to those doses, I get the response that my body needs. And then after eight, 12 weeks I can come back down to a low dose. In the process of having a load dose, the GLP-1s provide from an anti-aging inflammatory gut health standpoint. So maybe that's the future. Maybe blasting and cruising. I kind of joked about that on the live stream with Jay, but maybe blasting cruising GLPs is the because of the amazing benefits they provide.

25:32 So time will tell, and I'm sure there'll be much more things that come in the future that maybe far surpass what GOP wants to, but that's my guess. Why do GOP ones stop working and how to restart results? This is a good question. One, it goes back to the dose. So GOPs ones stopped working a lot of times because you've built up a tolerance to that dose, so you either need to increase the dos to keep getting the same effects you were getting before, or you have to come off. And this goes to back the question, right? Can we blast and cruise? can we do a little bit and then go up to dose we need and go back down to a bit, which would technically be our cycling off,

26:06 but I still get some of those like background benefits that we know are so powerful. They stop working because you build up a tolerance to them. And then also to, if you are simply blasting one pathway, which is the GOP-1 pathway. There's so many different areas in the body that work on fat loss. We've got mitochondrial health, we've hormone health with our reproductive hormones, We got the growth hormone pathway We've got all these different things. We got injectable carnitine. And if you're just using a GOP-1 peptide, it's going to help with fat loss, but there's other pathways that you can hit in order to continue pushing fat-loss

26:41 and push through plateaus. This seemed to be big for a few weeks. There was probably some news stories or something. I don't read the news, so I didn't know. But there seemed be a big thing with trisapatides affecting people with blindness suddenly when they first start taking it. I, again, I didn't see anything. No one sent me any articles about this, but apparently there's been a non-zero number of people that have gotten suddenly blind from taking Trisapatite. I don't know that that's Trasapatide. And I've never heard anyone directly report that back to me. It's all kind of hearsay.

27:11 However, if it is happening, and I would just say it's probably not Traspatide, It's probably, I mean, it could be, but it's something going on with that person's health. I would venture to guess they weren't in the best health initially. So I can't really speak to that. If you guys have, you know, reports or whatever, please send them my way. But I haven't dug deep enough in it to say, i'm not afraid to, say I don't know. And in this case I, don' know but my best guess would be you, know maybe it was something that that, person had, poor health before and increasing GLP-1 in,

27:41 the body, either kind of push them over the edge. Reddit TrueTide cycling, what should I replace it with? Well, I think what could work well alongside Reddit, True Tide, or you could intersperse this like in a four to eight week window off of Reddit true tide would be Krugrelentide. So Krugerlentides amazing. I've been using it now for probably about six weeks, and it really gives you the little bit of extra appetite suppression you need in way that is not similar to how GLP ones work in appetite, suppression. And what I mean by that, is the satiety I get from Kruegelentied is actually more of a mental satiety than it is a physical satiated in my stomach.

28:20 It's hard to explain unless you know and have done it, but the satiety is more mental, meaning that like I kind of just look at food when I'm eating, I get to the point, like, no, good, my brain is good. But I don't feel sick or nauseous. So now I am sure that's dose dependent. I m sure if you took enough grill and tide, you'd probably get nauseus because I've heard of people doing that. but I would say if want to cycle off at a true tide because that is the smart strategy, or even go down to a lower dose, but still have the appetite suppression. Coagulantide works great. Dosing wise, I would start with 0.25 milligrams two to three times per week, and then you can go all the way up there.

28:52 I know people are taking three or four milligrams a week. So again, use at your own risk. that would come from a higher dose of a GLP-1. You probably don't have as much of that with Krugrelen Tide, but there may be some other effects that I've heard people say they kind of feel anhedonia, which is just a lack of ability to feel pleasure of anything. And that may come come, from the fact that Kruegelen tide is working more in the brain because it's an amylin analog. So we'll see. But definitely Krugerlentide would be the answer to that.

29:24 What add-ons help with fat loss when on a GLP-1 long term? So good question. Kind of like I just mentioned a second ago, but what I would use alongside of a GOP1, definitely BAM15 and SLU PP332, shameless plug for Metashred, go get it from wherever you can find it out there because I think everyone should be taking that. Injectable oil, carnitine, 500mg to 1,000mgs a day. From there, I would look at growth hormone peptides, kind of like I mentioned, and then also too, hormone optimization is going to be the best thing for sustained metabolic health for the long run.

29:54 And then something, again, to hit that insulin pathway, so metformin slash and or dihydrobarbarine and, or Jardience and-or, you know, potentially something else like an alpha-lopoic acid or something that's kind working to help with insulin sensitivity and inflammation in the body. So those would be my off-the-dome answers. Servo-Dutide versus Trujapotide and Reddit TrueTide, what are those similarities and differences? So I think this is kind of where we get into this, where a pharmaceutical company is just working to come up with things so they can patent.

30:25 Servodutides, all it is, is basically is if you took Reddit true tide and you remove the GIP component. So trisapatite is GLP plus GIP, servidutide is GLP plus glucagon. So I personally, I don't think that would necessarily... I dont know why anyone would do that versus just taking rid of tritide. Other than the fact that you're buying it from a pharmaceutical company, maybe it's cheaper than retitrutide itself, which is still a research chemical. So, servidutide, think of retritrutite as GLP plus GIP plus glucagon, and then servadutite is just GLPs plus glucogon.

31:01 There's another one named masdutides which I think would probably have a little bit more utility because that removes the GLp1 component, so it is G.I.P. plus glucose. And in that case, some people just may have a bad reaction to the GLP-1. So if you don't do well on semaglutide itself, and you seem to do better on triseptide or retitrutide, maybe you would want to use mazutite. That would be my answer to that. But again, I think retritrutite, in a sense, is still going to be so much better because you're hitting all three pathways.

31:32 Let's move into a little bit of a hormone questions. So testosterone and high hematocrit, is TRT safe? So I think they'll cut off on the blood work for men from hematic or it's like 50. If you go to 51, they say you have high himatic and you got to donate blood. That's absolutely a farce. You definitely don't need to do that. I would say that hermeticret levels wise, I don't want to give a blanket answer because someone can have a 58 hematocrit and be totally healthy based on whatever else is going on in their body, but someone else could not and they could have high blood pressure and issues that the hematicret could be indicative

32:08 of something else wrong. However, generally, Generally speaking, the fear of high hematogrid TRT is completely overblown and it is absolutely safe. And even if it increases your hematurid to like 51, I think on my last blood work, mine was 51. Oh no, oh my goodness. I'm perfectly healthy. My blood pressure is totally fine. The inflammation in my body is still fine, so. Next question, optimal testosterone levels for a 59 year old man, I would say as high as you can get them without any side effects. It's going to be different for everyone. I'd say what you want to potentially look at.

32:38 The best that we have now is to look your free testosterone. And I'm not saying that's everything, but if your testosterone is over 40, then you're good. If you are not over forty as a fifty-nine year-old man. Well, you should do something about it. and I have rarely seen any 59-year-olds men that I've looked at their blood work that have over a 20, 22 free testosterone. So you're probably deficient if your free testosterone is not over 40. Um, there's this thing, uh, someone sent me this, a 17 alpha estradiol apparently is an estrdiol that is a non-feminizing form of estridiol, that men could supplement with.

33:15 I actually don't know anything about this. And I'm going to dig deeper and look further into this because I've actually began estrodiol micro supplementation alongside my testosterone therapy and it's done wonders. For me, I will say for mental health and heart health, and sexual health. But I don't know about this one. I got to do some more reading on that. So thank you, whoever sent that, And this is just a good plug. If you do come across stuff like this, send it my way if you think it could be useful to everyone out there. Post-cancer hormone use, should you take estrogen progesterone?

33:46 I personally would, but your doctor will never tell you. So I would take testosterone, estrogen, and progeterones as a woman. At the airing of this video, my WHI video should be out. You can go back and refer to that, post-cancer hormone. Your doctor never will let you because they'll tell your cancer is estrogen fed. But if you look at breast cancer, one in three women after menopause get breast cancer 1 in 48 get it before menipause what's one variable that they don't have testosterone and estrogen so and you know oftentimes progesterone too so can adding well speaking of can add low-dose estradiol to trt improve libido

34:23 absolutely a thousand percent and i think too if you're especially if your running lower estrogen In the 20s, you can absolutely bump that up into the 50s 60s 70s and even higher to improve sexual functions. So a lot of times you get estrogen as a man up to 100 and that's where your sexual function is going to be through the roof and you'll be uncontrollably horny. Funny enough, estrogen for men a lots of time dictates sex drive and testosterone for women dictated sex drives. Contrary to what most people think.

34:53 To go back to the hematocrit, someone asked me, how do I manage hematochrine RBC levels while on TRT? Well, one, you can improve your lifestyle. So if you improve, your cardiovascular fitness and endurance, You will likely bring down your hematechrit if it's high. Some people will say to donate blood. That's just the easy way to cop out. And over time you probably do more harm than good. But I would say the first thing is making sure that you're doing four to six cardio sessions per week of at least 30 to 45 minutes in zone two cardio.

35:24 At least bare minimum. And typically most people that do that are going to be completely fine with their hematocrit. So other than that, you can get into like taking natokinase or even I think telmasartan, which is a blood pressure medicine, probably helps a little bit of the whole picture there. But that would be my recommendation. What can postmenopausal women take instead of HGH and test SIP? You could take some bioregulators. You can take Xenolutin. I don't know why you wouldn't. So I dunno why someone wouldn' take testosterone, Sipunate, and HTH if you're a post menopause woman.

35:58 That's like saying, you don' have any vitamin D, but you refuse to supplement with vitamin. D. What Can I take Instead? It's Like, well, You Could Just Take Vitamin D And that would be my answer. I mean, sure. Can you take kids' Pepton? Sure. can you Take Ipramelin? sure, but why would you in this case? So I think hopefully one day the testosterone and growth hormone deficiency is addressed as easy as a vitamin D deficiency. So let's go into some blood sugar questions.

36:31 Is metformin necessary when using a GLP-1? No, but you should. So that's the short answer. Is it necessary? But it's a better, yes, absolutely a thousand percent, even if it was just 500 milligrams or a 1000 milligrams a day. Metformins and muscle loss, how to avoid it? Well, you avoid muscle eating protein, eating the amount of protein that you need and resistance training. And if you do that, you won't have to worry about metformin causing muscle loss, just as if your not taking met form, and you don't want to have worry bout muscle lost. So, um, You know, that's kind of my answer to that.

37:02 I have a video called a hundred reasons everyone should take Metformins. Met formin, hopefully after that it's a no brainer as to why you would take it. How do I use Met Formin properly? Very simple. If you're just starting out, if You're a woman and your smaller, I'd start with 250 and 250 milligrams AM and PM. then I would go up to 500 milligrams a.m. and p. m. That's where I'd start if I was a man. And then you can go from there, you could go all the way up 1,000 milligrams A.M. to 1 thousand milligrams P. M. If you're worried about some of the side effects right away, You can get the XOR version, which means Extended Release, and that tends to negate any of

37:33 those side-effects. So, there you go. Can metformin help gut health? Absolutely, a thousand percent. The primary way it does it a ton of ways is through upregulating achromatica, which is the good gut bacteria. So, met formin helps up-regulate my achormatia in the gut, thereby improving gut-health and thereby reducing systemic inflammation in body because of what it's doing to the guts. That would be my first line defense or first-line explanation as far as how met-formins helps gut Best approach for improving insulin resistance in diabetics,

38:08 kind of everything we talk about, microdose of a GLP-1 to start using metformin, living insulin controlled, fasting two to three days per week, doing resistance training, all those things help with insulin resistant. So there's one thing about diabetes type two, it can be reversed through diet and lifestyle changes. It is not a death sentence and it's not something you should quote unquote manage. You should eliminate it from your life. Let's talk about some longevity and mitochondrial stuff. So how long can mitochondria peptides be used safely?

38:39 They can be safely for the rest of your life. You just got to be smart about how you cycle them. I have a video called how to avoid a mitochondrion overspend and what you would do to cycle it. Refer back to that video for a long explanation. Basically, you could use one mitochondrial peptide for month one, the next one for my two, then next from my three, and then take a month off. And then also use antioxidants like injectable glutathione, like urolithin A to help with the mitochondria recycling process. You can take things like carbon 62. So that's the answer.

39:11 SLUPP332 and mitochondrial dysfunction, how to detect and fix it. I don't know if this person is referring to SL you causing mitochondria dysfunction or improving it, but you could definitely, I would say mitochondrion dysfunction you'll know you have because you feel exhausted all the time. And SL, you can definitely improve this and you probably need a higher dose closer to like two milligrams a day. If you severe mitochondrical dysfunction. But there are blood markers you can look at, like inflammation, things like that. So that's where I would start.

39:42 Someone says SS-31, Huminin and Matzi for CKD, which is chronic kidney disease dosages. I'd start with 10 milligrams of SS 31 per day and give that at least 30 days. You could place in Humenin and matzi, but I'll just start there because a lot of times that is going to get you going in the right direction. Someone says oxytocin for weight loss and body recomp best dosing schedule. I think Alex had talked about this at one point. People love to just say the word recomp because what that means is they need to lose fat a lot of times, but they don't have any muscle or their skinny fat.

40:12 So he's like, yeah, I need a recomp, which means that they have the amount of muscle they want and they needed to loose fat the first thing you need. To do is lose that like point blank period. Yes, you should resistance train in the process of losing fat, grossly confused about Recomping because what they really are saying is that like I look sloppy and I want to look better and the best thing you do to Look better first is to lose fat and in the process you're doing resistance training to like maintain muscle But you are not going to be a chloric surplus to build muscle because you obviously need to loose fat now best dosing schedule you could

40:49 do I would do start with a It's different for everyone, but you could start with 50 micrograms injected pre-workout and see how you feel. And then that's going to be the easiest thing to do and just do that pre workout. Then you can potentially go up to a hundred micro grams. Typically like the longer you do it, the higher the dose you run. You can use the nasal spray in like a 100 micro-gram but I think the injectable is so much better. Anything over that can oftentimes cause a really aggressive bowel movement, so you probably wouldn't want to take that pre-workout.

41:19 But I would just say pre workout, take 50 micrograms, work up to 100 micro grams and use that and see how your response is. It's pretty cool because it does rewire your brain to enjoy the activity that you do. after you use the oxytocin. So if you don't like working out, it could help, but there's no magic formula for like oxy tosin and recomp other than to just use it and train. Let's talk about some autoimmune disease stuff. Best peptides for lupus. I think you could lump in a lot of these autoimmune diseases together.

41:50 And I'm going to talk about this. So I'll probably repeat myself a little bit here. Best type for Lupus, which is low platelets, muscle pain, hair thinning. Thymus and Alpha-1 would be the first line of defense. Then you can look at LL-37, thymalin, within A I believe is the immune peptide there. and then I would look the Immune Bioregulator stack like Vladonix, and there's a couple others in that stack to help there, Same thing, peptides for autoimmune diseases like arthritis and Hashimoto's, thymus and alpha-1, LL-37, the auto immune stack of the bioregulators,

42:28 and then for arthritis you can also add in BPC-157-TB500. Peptides for long CV, POTS, and Ehlers-Danlos and younger individuals, same thing. So thiamin-sulfo-1, LL-37, BPC-177, TB-500. Thyroid, health, peptides, for grave disease, again, pretty much the same. I would say in these cases too, I would look at testosterone deficiency. I think a lot of these autoimmune diseases, you know, severe, CFS, all these things can be greatly improved by supplementing with hormones and what hormones do,

43:05 because a lotta times these people have severely low hormones. It's kind of like you look at it, if you looked at from the outside looking in, you'd look objectively like, why does someone have no energy? Why does somebody have all these things? Now, is hormones going to fix every single thing? No, but I'm telling you if someone came up to me and said like hey, I have these symptoms, they didn't say it was an autoimmune disease, let's say you have testosterone deficiency, man or woman, and I would look testosterone replacement immediately. You almost never hear someone on therapeutic testosterone talk about having an autoimmune disease.

43:38 Why? Because testosterone helps all those things. So for any of you out there that are listening that trying to solve an Autoimmune Disease, whether it's for yourself or a loved one, please, look at testosterone. And even if you're a younger person, I know 20 year old women that have severe testosterone deficiencies because they've been on birth control. What are you going to do about it? Are you gonna take thymosanol for one? Yeah, sure. Is that gonna help? But it's not gonna replace the testosterone. So that's the thing I'll say kind of like putting the lid on autoimmune disease is sure there's all these other things out there that can help.

44:08 You can even look into mitochondrial peptides like SS31, MOTC, and humanin, but please look at testosterone for people that are afflicted with auto immune disease. Let's talk about some, some mental peptides. So peptide is for anhedonia, motivation, ADHD. That's a tough one. I, you know, when talking about the cognitive things, it's tough because everyone is so neurochemically different. So like someone will respond great to one cognitive peptide and someone won't feel anything and other people may get an adverse reaction to it.

44:43 I would say for anhedonia, motivation 8 HD, a lot of times that can be a dopamine thing. You could look at like 9 MEBC. Um, I wouldn't say all people should have alpha GPC. That's a great, uh, basically way to help with choline in the brain. And then I think too, for some of those things that if people have really, really bad ADHD, look at methylation pathways in the body and look like how you're supplementing with methylated vitamins, methylated B12, methylfolate, and then also to how much phytic acid you are getting,

45:19 because I thing a lot of that is, a lof those neurochemistry things come from poor methyulation. that end up going into your brain, that ends up affecting the neurochemistry of your brains. So there's things you can take. You can test of benzene, you take all that stuff, but this is one that a lot of people are just going to have to try. We also have a new, nootropic coming called Biomind that has a really cool product called J147, and it's got dihexanupep, which are all great, But some people might not respond the best of those. I don't want to give that as like a blanket, like, hey, just take this and that's going fix all those things.

45:52 Next question, does BPC-157 improve mood? I think it does, but for some people can also down-regulate, well it technically down regulates dopamine, so for people it might not. Now for me, I feel like I'm in a better mood when I have Bpc- 157 because I thing it's clearing inflammation in my brain that may have accumulated through several concussions over my lifetime. So that's kind of the answer is yes, but just understand that it does down-regulate dopamine in the brain. In acetyl-C-link amidate for stress relaxation, I would say start with 500 micrograms and then you can move up to one milligram.

46:24 But it definitely works. Again, it just depends on how well you respond to it. Peptides in women's health, best weight loss and anti-aging stack for women, 50 plus, that doesn't increase cortisol. I would say testosterone, probably estradiol if you are post-menopausal, progesterone are going to be the best thing for weight-loss, and then I will throw in human growth hormone, then you know, 1.5 to 2 milligrams of red trutide per week.

46:54 I would throw in SLU PP332 and BAM15. And from there, I think you will be well on your way. Maybe even throw on some injectable carnitine 500 milligrams to 1000 milligrams per Someone asked about for women, peptides for fertility, pregnancy, prep and pregnancy. I'm not going to go super deep on this just because I am not as well versed in it, but I will say for Taylor and I, I think a lot of women actually can improve their menstrual cycle through a therapeutic dose of testosterone.

47:28 with testosterone than without it. And then from there, I would say just live insulin-controlled. A lot of times a GLP-1 peptide can help get rid of PCOS or some of these things that impair fertility in women. So I'd say a microdose of a glp-one peptid would also be a good place to start, but from here it gets much more deep for women, so I don't want to take a whole hour to talk about that. I'll do a separate one on that Peptides for menopausal fat loss, is NAD plus the best option?

47:58 No, it's not the option. It's a good option to throw in, but again, hopefully you notice a common theme here of a lot of questions I get about menipause, and rightly so because meni-posal women are the most underserved market. You need testosterone, I will say it time and time again. I'll probably say million times the rest of my life. Postmenopausal women for fat loss need testosterone. Then once that's addressed, you can move to addressing the thyroid through desiccated thyroid. You can address the insulin pathway with the GLP-1 peptide to help with fat lost, but it's always going to go back to that.

48:32 There's no peptides that is going magically create fat lose when you don't have hormones in your body. I hate to be the bearer of bad news, that what it is. Hairy growth for women with male pattern hair loss. This is a tough one. I don't know if this is dependent or independent of maybe their testosterone use. One, you could have low testosterone, which could actually make the hair loss worse. You definitely have some thyroid issues, and I think desiccated thyroid supplementation would help with that.

49:06 But yeah, that's a tough one. Again, I don't know, as far as like a women's stack for hair-loss, what would be the best thing. She can obviously use GHK products to help her with hair lost. That does really well. GH K with carbon 60 for her loss. If you apply that topically, it works really And then we're just going to kind of get into some miscellaneous questions. So fat loss stack for fasted cardio, L-carnitine, the shredder, etc. All those are good. The shreder does have L carnitin in it. I would say like I kind have like a like an arsenal that I will just rotate through for my fasted cardio.

49:40 So like for today, today I did fast cardio and I took Shred X, which has SLU, Carterine and Liposomal AOD. And I take five milligrams of Albuterol and that was great. Then I Biosculpt which is the cream product and rubbed that on my abs. It increases localized heat and sweating in your abs to just burn a little bit extra fat there. There's a ton of products from Amino Asylum that you can go crazy with. I will say maybe one thing just to give you guys a nugget to not be a broken record.

50:10 There is a product there called Pyro and that is albuterol and yohimbine injectable. And I did 20 units of that one time and it was some of the craziest sweat that I did. Now it wasn't fun and it will like send your heart rate through the roof. So you, the funny thing is you take that and you have no choice but to do cardio after. You have to, otherwise you will go nuts because your heartbeat will grow up. I would say avoid that if you're someone that's like sensitive to stimulants or whatever. But I had 20 units of that.

50:40 And literally within five minutes, I was like, Oh my goodness. It was an amazing cardio session. My endurance was crazy. Obviously, the localized heat from the yohimbine, because that kind of burns fat and stubborn fat areas, was really good too. Raw wall scene is the alpha yhimbene that works really well. You can use that too, like three milligrams, six milligrams of raw wall seen is going to take two. Coagulantide, how does it fit into fat loss protocols? I think coagulentide is really a lever that you can use to basically turn on and off your appetite when you need it, when don't.

51:14 And if you're microdosing it you kind of attack the next one to two days with your appetites and then it kind wears off because you are doing a little dose and you use it from there. So I thinks it's a level that allows you to control your hunger as needed. If your hung is through the roof you could use that to increase it the dosing and the frequency to move the hunger up or down. It's not going to do anything to like necessarily drive fat loss the way Reddit True Tide will. However, it allows us to kind of have a lever on our appetite, which is pretty nice. Like at what time in human history could you say that you could just lose fat? It will, because you can control your appetite.

51:45 It was pretty cool. Next one, BPC-137 in angiogenesis. Does it increase cancer risk? No, it doesn't in practice. But if you listen to big name influencers that love to scare people away from peptides, yes, It will. So I would just say, no, doesn' t. That's the last thing I'm worried about. I wouldn't mind using Bpc-127 every day for the rest of my life if I had to. Uh, I m not going to worry about that. Can Matzi and L-Carnitine raise heart rate? They definitely can.

52:15 I have seen L Carnitin raise my resting heart, which I don't get all upset about. But if you have a high resting rate and you don' want to be higher, yes they will. And the Matzzi, not so much in my experience with L carnitene can just because of what it does, but it's not like overwhelming. When I sleep, a lot of times is right around 58, 59, 60. Maybe it goes up to 65, 70 again. And then it kind of normalizes once I started using it every day. But when you first introduce it, you will have like a one to two day period where it does.

52:46 Again, I'm not super worried about that because I know what's going on. I knew what I was doing and I don't freak out. So injectable versus oral acetylal carnitine, which is better. Well, if you inject L-carnitin, it's just L carnotine. It's not acytole carnatine but acytole carnutine is for the brain. You notice more of a cognitive pick-me-up from it, whereas the injectable is more systemic. You noticed fat loss, muscle building, increased mitochondrial health and everything there. So I would definitely say the Injectable's always going to be better, but you can stack them together too. And you could stack the oral at 1,500 to 2,000 milligrams per day alongside the 500 to 1 thousand milligrams.

53:30 PPC and TB 500 blend to one vial, how to adjust dosing. You don't really adjust those things because they're in there together. So I would just add usually two milliliters of water to the vile if it's a five and five blend and then take 10 to 20 units depending on what you need it for. Someone sent me info on a peptide called SB-01 for degenerative disc disease. I don't know anything about it. But I did do a little bit of reading on it and it looks promising. If people are out there, let the community do what it does and go find information on that and hey, maybe it will be something that we can end up bringing

54:08 to the market. Peptides for lung health, COPD, phlegm, et cetera. There's, I would say first there's a bioregulator stack for respiratory health that will help a lot. If you look at the literature, and I don't need to go into it in this video, but you can look the legislature, the bi oregulators stack, for long health. there is one called tax arrest in there. That's the bio regulator for your lungs works really well. From there, would look Thymus and Alpha-1. LL37 and then another peptide called VIP.

54:38 I would also probably look at a peptid called KPV as well. That does really well for inflammation. So I say if you're doing injectable peptides, Ll37, VIP, KP and thymus and alpha 1 are a really good start and throw in the lung health or the bioregulator stack for respiratory health and you'll be well on your way. By regular timing, do I take it with food or before meals? Yes, you do want to take with it before meal. I've actually had a lot of people asking, can I not take them when I'm fasting? It's better according to the manufacturers and the creators of those to them with the food.

55:08 And so I would say if you're fasting, just wait and take your two capsules with your meal of the day. If you are waiting later to eat dinner. Or if your just fasting for the whole day, wait, and you can double the dose up when you take the next time. So you totally fine with that. It is technically better to take it with food, which I know goes against a lot of the other things that we take in regards to peptides. How can it make peptide injections less painful? Well, it kind of depends on the peptides. Some peptids are just going to hurt point blank period. You can always add in more backwater if the peptide stings really bad.

55:39 And typically that will negate the sting. Sometimes too, if you actually inject intramuscularly, It burns a little bit less than if inject subcutaneously, you at least a lot of times have less of an immune response that way. So it's kind tough. some of them just burn. It's tough, sorry. Can BPC-177TB500 use as a nasal spray or use it as an eye drop? I actually have been experimenting with it. It's an eyedrop for the last couple of days. I want to give it some more time before I make a comprehensive video, but yes, you definitely can.

56:11 it seems to have working, been working pretty well, But the verdict is out for it, at least for me to see what it does. So I'm going to it a few more days before the ways that I'm doing it and how to do it. You can use it as a nasal spray, too. I know companies make that. Does it work? Probably not. If anything, it's helping with brain inflammation, I would think, if you're taking it is a nail spray. But if have a bum shoulder and you snort BPC-TB nasal-spray, you probably not going to anything. VIPs, in the last question, will be VIP nasal versus sub-q injection, which is better.

56:41 In the case of VIP, it's almost always made as a nasal spray, and because it is more one that works on the lungs, probably the nasal is spray is probably better, actually off the top of my head I don't even know the subq dosing for VIP so I'd have to look that up, but almost with VIP at least in reading that I can find the nasals spray works better so. That is that. And coming right up on an hour, that is all of the questions. So that was the question from the last month since the Q&A video.

57:11 I think I got everything in there, at least everything that was worth doing. So again, thank you guys so much for the questions that you submit to me. These are the most powerful things because for me, it kind of gives me an indicator of where the audience is at, what you need help with, and how I can make that happen based on everything I know and learn and do. I appreciate you, guys, so, much. To close out, obviously, you know where to sign up for email newsletter and all that stuff. There's a lot of very valuable information on there that is not necessarily on YouTube.

57:41 And also in the private community, there's even that much more valuable that's not on Youtube. So thank you guys for everyone that in those communities. At the end of the day, I just want to say thank to everyone out there who supports me and the people alongside me in this journey. It means the world to me. I am humbled and privileged every single day and I mean it from the bottom of my heart. Every day I overflow with gratitude seriously to get to do what I do. So I thank you guys You make this so enjoyable for me and I really I feel I have the best audience the world Yeah, you might have a negative person here

58:12 and there but really for the amount of people that I just get an outpouring of support from each and every day Thank you, guys. You made this not only worth doing, but I get up excited every day to get to this. So this is what I planned on doing for the long haul. And I definitely know that this Is my purpose and I can't thank you guys enough for helping affirm that for me. But then also just being a support there. Thank you so much. That's it for this one. Don't forget, check the question box, submit your questions there and i will see you in the next one, peace.